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| 1 | The Heat Transfer Coefficients of the Heating Surface of 300 MWe CFB Boiler显示文摘A study of the heat transfer about the heating surface of three commercial 300 MWe CFB boilers was conducted in this work. The heat transfer coefficients of the platen heating surface, the external heat exchanger (EHE) and cyclone separator were calculated according to the relative operation data at different boiler loads. Moreover, the heat transfer coefficient of the waterwall was calculated by heat balance of the hot circuit of the CFB boiler. With the boiler capacity increasing, the heat transfer coefficients of these heating surface increases, and the heat transfer coefficient of the water wall is higher than that of the platen heating surface. The heat transfer coefficient of the EHE is the highest in high boiler load, the heat transfer coefficient of the cyclone separator is the lowest. Because the fired coal is different from the design coal in No.1 boiler, the ash content of the fired coal is much lower than that of the design coal. The heat transfer coefficients which calculated with the operation data are lower than the previous design value and that is the reason why the bed temperature is rather high during the boiler operation in No.1 boiler. | WU Haibo ZHANG Man LU Qinggang SUN Yunkai | 2012 | Journal of Thermal Science2012，21，4： | 3 |
| 2 | Effects of Statin Therapy on Inflammatory Markers in Chronic Heart Failure: A Meta-analysis of Randomized Controlled Trials显示文摘 | Lei Zhang Shuning Zhang Hong Jiang Aijun Sun Yunkai Wang Yunzeng Zou Junbo Ge Haozhu Chen | 2010 | Archives of Medical Research2010，，6： | 1 |
| 3 | Phosphorylation of PHF2 by AMPK releases the repressive H3K9me2 and inhibits cancer metastasis显示文摘Epithelial to mesenchymal transition (EMT) plays a crucial role in cancer metastasis, accompanied with vast epigenetic changes.AMP-activated protein kinase (AMPK), a cellular energy sensor, plays regulatory roles in multiple biological processes. Although afew studies have shed light on AMPK regulating cancer metastasis, the inside epigenetic mechanisms remain unknown. Herein weshow that AMPK activation by metformin relieves the repressive H3K9me2-mediated silencing of epithelial genes (e.g., CDH1)during EMT processes and inhibits lung cancer metastasis. PHF2, a H3K9me2 demethylase, was identified to interact with AMPKα2.Genetic deletion of PHF2 aggravates lung cancer metastasis and abolishes the H3K9me2 downregulation and anti-metastasis effectof metformin. Mechanistically, AMPK phosphorylates PHF2 at S655 site, enhancing PHF2 demethylation activity and triggering thetranscription of CDH1. Furthermore, the PHF2-S655E mutant that mimics AMPK-mediated phosphorylation status further reducesH3K9me2 and suppresses lung cancer metastasis, while PHF2-S655A mutant presents opposite phenotype and reverses the antimetastasiseffect of metformin. PHF2-S655 phosphorylation strikingly reduces in lung cancer patients and the higherphosphorylation level predicts better survival. Altogether, we reveal the mechanism of AMPK inhibiting lung cancer metastasis viaPHF2 mediated H3K9me2 demethylation, thereby promoting the clinical application of metformin and highlighting PHF2 as thepotential epigenetic target in cancer metastasis. | Ying Dong Hao Hu Xuan Zhang Yunkai Zhang Xin Sun Hanlin Wang Weijuan Kan Min-jia Tan Hong Shi Yi Zang Jia Li | 2023 | Signal Transduction and Targeted Therapy2023，8，4： | 1 |
| 4 | Parametric analysis and multiobjective optimization for functionally graded foam-filled thin-wall tube under lateral impact 显示文摘 | FANG Jianguang GAO Yunkai SUN Guangyong | 2014 | Compu Mate Sci2014，90，： | 1 |
| 5 | Determination of zinc in food using atomic fluorescence spectrometry by hydride generation from organized media 显示文摘 | Sun Hanwen Suo Ran Lua Yunkai | 2002 | Analytica Chimica Acta2002，457，2： | 1 |
| 6 | The thermal- hydraulic calculation and analysis of the medium temperature platen superheater in a 300 MWe CFB boiler 显示文摘 | Wu Haibo Zhang Man Sun Yunkai | 2013 | Powder Technology2013，235，： | 1 |
| 7 | Simultaneous determination of trace cadmium and mercury in Chinese herbal medicine by none-dispersive atomic fluorescence spectrometry using intermittent flow vapor generator 显示文摘 | Sun Hanwen Suo Ran Lo Yunkai | 2003 | Analytical Sciences2003，19，7： | 1 |
| 8 | Simultaneous determination of trace cadmium and mercury in Chinese herbal medicine by dispersive atomic fluorescence spectrometry using intermittent flow vapor generator显示文摘 | Sun Hanwen Suo Ran Lo Yunkai | 2003 | Analytical Sciences2003，19，7： | 1 |
| 9 | Neurobiological mechanisms and related clinical treatment of addiction: a review显示文摘Drug addiction or substance use disorder(SUD),has been conceptualized as a three-stage(i.e.binge/intoxication,withdrawal/negative affect,and preoccupation/anticipation/craving)recurring cycle that involves complex changes in neuroplasticity,reward,motivation,desire,stress,memory,and cognitive control,and other related brain regions and brain circuits.Neuroimaging approaches,including magnetic resonance imaging,have been key to mapping neurobiological changes correlated to complex brain regions of SUD.In this review,we highlight the neurobiological mechanisms of these three stages of addiction.The abnormal activity of the ventral tegmental,nucleus accumbens,and caudate nucleus in the binge/intoxication stage involve the reward circuit of the midbrain limbic system.The changes in the orbitofrontal cortex,dorsolateral prefrontal cortex,amygdala,and hypothalamus emotional system in the withdrawal/negative affect stage involve increases in negative emotional states,dysphoric-like effects,and stress-like responses.The dysregulation of the insula and prefrontal lobes is associated with craving in the anticipation stage.Then,we review the present treatments of SUD based on these neuroimaging findings.Finally,we conclude that SUD is a chronically relapsing disorder with complex neurobiological mechanisms and multimodal stages,of which the craving stage with high relapse rate may be the key element in treatment efficacy of SUD.Precise interventions targeting different stages of SUD and characteristics of individuals might serve as a potential therapeutic strategy for SUD. | Yehong Fang Yunkai Sun Yi Liu Tieqiao Liu Wei Hao Yanhui Liao | 2022 | Psychoradiology2022，2，4： | 1 |
| 10 | High-Order Extended Strong Tracking Filter显示文摘A novel High-order extended Strong tracking filter(H-STF) is proposed for a class of nonlinear systems. All high-order polynomial terms in the state model are regarded as implicit variables;the original state model is equivalently formulated into a pseudo-linear form;the dynamic relationship between each implicit variable and all variables is modeled;original state model is rewritten into an augmented linear model;the nonlinear measurement model can be rewritten into linear form;taking into account the problems of modeling errors and state mutations that may be caused by the introduction of implicit variables, a high-order extended strong tracking filter is designed. Examples are presented to demonstrate the effectiveness of the new algorithm. | SUN Xiaohui WEN Tao WEN Chenglin CHENG Xingshuo WU Yunkai | 2021 | Chinese Journal of Electronics2021，30，6： | 1 |
| 11 | Study on adsorption of Th (IV) using surface modified dibenzoylmethane molecular imprinted polymer显示文摘 | JI Xuezhen LIU Huijun SUN Yunkai | 2013 | Journal of Radioanalytieal and Nu- clear Chemistry2013，295，1： | 1 |
| 12 | Determination of zinc in food using atomic fluorescence spectrometry by hydride generation from organized media显示文摘 | SUN Hanwen SUO Ran LU Yunkai | 2002 | Anal Chim Acta2002，457，： | 1 |
| 13 | Impact Increment Based Hybrid Reliability Assessment Method for Transmission Systems显示文摘This paper proposes an impact-increment-based hybrid(IIHybrid)reliability assessment approach for power transmission systems.The proposed approach integrates the advantages of the impact-increment-based state enumeration method(IISE)and impact-increment-based Monte Carlo simulation(IIMC)to improve computational efficiency and accuracy.The IISE can efficiently assess the impacts of low-order contingencies.The accuracy is,however,sacrificed as highorder contingencies are usually neglected.The IIMC is more suitable for large-scale contingency spaces compared with IISE,although the calculation process is time-consuming.In this paper,the proposed IIHybrid takes advantage of its strengths while avoiding its shortcomings.The IISE and the IIMC are applied to lower and higher contingency spaces respectively.The high-order contingencies elimination technique proposed in our previous studies is still applicable to the IIHybrid.In addition,efficiency can be controlled by modifying the preset parameters to adapt to various scenarios.Case studies are performed on the IEEE 118-bus test system and PEGASE System.The results show that the proposed approach is more efficient and practicable than traditional methods. | Yunkai Lei Yeguang Sun Kai Hou Pei Zhang Lewei Zhu Xiaoxi Yang Xiaonan Liu | 2022 | CSEE Journal of Power and Energy Systems2022，8，1： | 1 |
| 14 | A CRISPR activation screen identifies genes that enhance SARS-CoV-2 infection显示文摘Dear Editor,Identifying the host factors that are utilized for virus infection and mapping their cell-type expression profile can help to understand the viral tissue/organ tropism and pathogenesis.Much effort has been devoted to the identification of SARS-CoV-2 infection-dependent host factors.CRISPR-based activation(Konermann et al.,2015). | Fei Feng Yunkai Zhu Yanlong Ma Yuyan Wang Yin Yu Xinran Sun Yuanlin Song Zhugui Shao Xinxin Huang Ying Liao Jingyun Ma Yuping He Mingyuan Wang Longhai Tang Yaowei Huang Jincun Zhao Qiang Ding Youhua Xie Qiliang Cai Hui Xiao Chun Li Zhenghong Yuan Rong Zhang | 2023 | Protein & Cell2023，14，1： | 0 |
| 15 | A Dual-Promoter Gene Orchestrates the Sucrose-Coordinated Synthesis of Starch and Fructan in Barley显示文摘因为它在植物个体发生和复制期间为生长和开发保证精力供应,顺序的糖类合成为植物幸存是重要的。淀粉和 fructan 是在许多 flowering 植物并且在人的食谱的二个重要糖类。理解这协调淀粉和 fructan 合成并且解开植物怎么分配 photosynthates 并且为幸存优先考虑不同糖类合成,能为更大的食物的目的在农业导致改进到谷物 ? 安全和生产质量。这里,我们在大麦从单个基因报导一个系统 ? 雇用二个其他的倡导者,一 intronic/exonic,产生二个重叠顺序却机能上地反对的抄写因素在察觉到蔗糖,潜在地经由 sucrose/glucose/fructose/trehalose 6 磷酸盐发信号。系统在在一个倡导者上察觉一项控制蔗糖的 trans 活动并且安排采用自动调整的机制 ? 由另外的倡导者上的竞争抄写因素绑定的协调淀粉和 fructan 合成。作为在为系统的生理的角色的点的一个案例,我们证明了这个多任务系统能在与 fructan 的定制的数量引起大麦生产健康食物成分被利用。在招待基因的一个 intron/exon-spanning 倡导者的鉴定,与不同功能导致蛋白质,增加植物染色体的复杂性。 | Yunkai Jin Mingliang Fei Sara Rosenquist Lu Jin Suresh Gohil Corine Sandstrom Helena Olsson Cecilia Persson Anna-Stina Hoglund Gunnel Fransson Ying Ruan Per Aman Christer Jansson Chunlin Liu Roger Andersson Chuanxin Sun | 2017 | Molecular Plant2017，10，12： | 0 |
| 16 | Polycyclic aromatic hydrocarbons in benthos of the northern Bering Sea Shelf and Chukchi Sea Shelf显示文摘Eighteen polycyclic aromatic hydrocarbons(PAHs)were detected in benthos collected onboard the‘Snow Dragon’in the Northern Bering Sea Shelf and Chukchi Sea Shelf during the 6 th Chinese National Arctic Research Expedition(CHINARE 2014).18 PAHs for all biota samples ranged from 34.2 to 128.1 ng/g dry weight(dw),with the highest concentration observed in fish muscle(Boreogadus saida)samples close to St.Lawrence Island.The PAH composition pattern was dominated by the presence of lighter 3 ring(57%)and 2 ring(28%)PAHs,indicating oil-related or petrogenic sources as important origins of PAH contamination.Concentrations of alkyl-PAHs(1-methylnaphthalene and 2-methylnaphthalene)were lower than their parent PAH(naphthalene)in all biological tissue,and their percentage also decreased significantly(p<0.05)compared with those in the corresponding sediment.There were no significant relationships between PAH concentrations and trophic levels,which is possibly due to the combined results of the complex benthic foodweb in the subarctic/Arctic shelf region,as well as a low assimilation/effective metabolism for PAHs.According to toxic potency evaluation results from TCDD toxic equivalents(TEQs)and Ba P-equivalent(Ba PE)values,whelk(Neptunea heros)and starfish(Ctenodiscus crispatus)are two macroinvertebrate species showing relatively higher dioxin-like toxicity and carcinogenic risk. | Yuxin Ma Yurong Sun Yunkai Li Hongyuan Zheng Wenying Mi | 2020 | Journal of Environmental Sciences2020，32，11： | 0 |
| 17 | Telemedicine and digital management in repair and regeneration after nerve injury and in nervous system diseases显示文摘To the editor,We read with interest the article,'Facilitating transparency in spinal cord injury studies using data standards and ontologies'by Professor Vance P.Lemmon,University of Miami,USA(Lemmon et al.,2014)and would like to add to the discussion on digital management in spinal cord injury.We have analyzed the advancements in the treatment of | Weijun Zhu Yunkai Zhai Dongxu Sun Jie Zhao | 2014 | Neural Regeneration Research2014，9，16： | 0 |
| 18 | The Research of an Incremental Conceptive Clustering Algorithm and Its Application in Detecting Money Laundering显示文摘Considering the constantly increasing of data in large databases such as wire transfer database, incremental clustering algorithms play a more and more important role in Data Mining (DM). However, Few of the traditional clustering algorithms can not only handle the categorical data, but also explain its output clearly. Based on the idea of dynamic clustering, an incremental conceptive clustering algorithm is proposed in this paper. Which introduces the Semantic Core Tree (SCT) to deal with large volume of categorical wire transfer data for the detecting money laundering. In addition, the rule generation algorithm is presented here to express the clustering result by the format of knowledge. When we apply this idea in financial data mining, the efficiency of searching the characters of money laundering data will be improved. | CHEN Yunkai LU Zhengding LI Ruixuan LI Yuhua SUN Xiaolin | 2006 | Wuhan University Journal of Natural Sciences2006，11，5： | 0 |
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