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| 1 | Regeneration performance and carbon consumption of semi-coke and activated coke for SO_2 and NO removal显示文摘To decrease the operating cost of flue gas purification technologies based on carbon-based materials, the adsorption and regeneration performance of low-price semi-coke and activated coke were compared for SO2 and NO removal in a simulated flue gas. The functional groups of the two adsorbents before and after regeneration were characterized by a Fourier transform infrared(FTIR) spectrometer, and were quantitatively assessed using temperature programmed desorption(TPD) coupled with FTIR and acid–base titration. The results show that semi-coke had higher adsorption capacity(16.2% for SO2 and 38.6% for NO) than activated coke because of its higher content of basic functional groups and lactones. After regeneration, the adsorption performance of semi-coke decreased because the number of active functional groups decreased and the micropores increased. Semi-coke had better regeneration performance than activated coke. Semi-coke had a larger SO2 recovery of 7.2% and smaller carbon consumption of 12% compared to activated coke. The semi-coke carbon-based adsorbent could be regenerated at lower temperatures to depress the carbon consumption, because the SO2 recovery was only reduced a small amount. | Song Ding Yuran Li Tingyu Zhu Yangyang Guo | 2015 | Journal of Environmental Sciences2015,27,8: | 17 |
| 2 | Epigenetic reprogramming, gene expression and in vitro development of porcine SCNT embryos are significantly improved by a histone deacetylase inhibitor--- m-carboxycinnamic acid bishydroxamide (CBHA)显示文摘施主原子核的不够的 epigenetic reprogramming 被相信是哺乳动物的体的房间的低发展效率的最重要的原因之一原子转移(SCNT ) 。以前的研究两个都显示出那在里面 vitro 并且在老鼠 SCNT 的 vivo 开发,胚胎能被处理与各种各样的 histone deacetylase 禁止者( HDACi )显著地增加包括 Trichostatin A , Scriptaid ,和 m-carboxycinnamic 酸 bishydroxamide ( CBHA ),在哪个仅仅 CBHA 的效果还没在另外的种类被测试了。在这份报纸,我们在猪的 SCNT 胚胎的发展检验 CBHA 处理的效果。我们发现了为 CBHA 处理的最佳剂量和时间:在激活以后为 24 h 与 2 mol/L CBHA 孵化 SCNT 胚胎能从 12.7% ~ 26.5% 增加胚囊率。Immunofluorescence 结果证明在 histone 的 acetylation 的水平 3 离氨酸 9 (AcH3K9 ) ,在 histone 的 acetylation 3 离氨酸 18 (AcH3K18 ) ,并且在 histone 的 acetylation 4 离氨酸(AcH4K16 ) 16 在 CBHA 处理以后被提起。同时, CBHA 处理改进了联系象 pou5f1, cdx2,和象 igf2 一样的印的基因那样的基因的开发的表达式。尽管有这些在 vitro 结果和 histone reprogramming 答应,完整的术语发展显著地没在处理以后被增加。在结论, CBHA 改善在里面猪 SCNT 胚胎的 vitro 开发,增加全球 histone acetylation 并且在早阶段改正一些发展地重要的基因的表示。作为在老鼠 SCNT,我们早在猪显示出那原子 epigenetic reprogramming SCNT 胚胎能被 CBHA 处理修改。 | Yuran Song Tang Hai Ying Wang Runfa Guo Wei Li Liu Wang Qi Zhou | 2014 | Protein & Cell2014,5,5: | 9 |
| 3 | Adsorption and desorption of SO_2, NO and chlorobenzene on activated carbon显示文摘Activated carbon(AC) is very effective for multi-pollutant removal; however, the complicated components in flue gas can influence each other's adsorption. A series of adsorption experiments for multicomponents, including SO_2, NO, chlorobenzene and H2 O,on AC were performed in a fixed-bed reactor. For single-component adsorption, the adsorption amount for chlorobenzene was larger than for SO_2 and NO on the AC. In the multi-component atmosphere, the adsorption amount decreased by 27.6% for chlorobenzene and decreased by 95.6% for NO, whereas it increased by a factor of two for SO_2,demonstrating that a complex atmosphere is unfavorable for chlorobenzene adsorption and inhibits NO adsorption. In contrast, it is very beneficial for SO_2 adsorption. The temperature-programmed desorption(TPD) results indicated that the binding strength between the gas adsorbates and the AC follows the order of SO_2> chlorobenzene > NO. The adsorption amount is independent of the binding strength. The presence of H2 O enhanced the component effects, while it weakened the binding force between the gas adsorbates and the AC. AC oxygen functional groups were analyzed using TPD and X-ray photoelectron spectroscopy(XPS) measurements. The results reveal the reason why the chlorobenzene adsorption is less affected by the presence of other components. Lactone groups partly transform into carbonyl and quinone groups after chlorobenzene desorption. The chlorobenzene adsorption increases the number of C = O groups, which explains the positive effect of chlorobenzene on SO_2 adsorption and the strong NO adsorption. | Yuran Li Yangyang Guo Tingyu Zhu Song Ding | 2016 | Journal of Environmental Sciences2016,28,5: | 8 |
| 4 | Evaluation of sulfur trioxide detection with online isopropanol absorption method显示文摘Measurement of the SO_3 concentration in flue gas is important to estimate the acid dew point and to control corrosion of downstream equipment. SO_3 measurement is a difficult question since SO_3 is a highly reactive gas, and its concentration is generally two orders of magnitude lower than the SO_2 concentration. The SO_3 concentration can be measured online by the isopropanol absorption method; however, the reliability of the test results is relatively low. This work aims to find the error sources and to evaluate the extent of influence of each factor on the measurement results. The test results from a SO_3 analyzer showed that the measuring errors are mainly caused by the gas–liquid flow ratio, SO_2 oxidation, and the side reactions of SO_3. The error in the gas sampling rate is generally less than 13%. The isopropanol solution flow rate decreases 3% to 30% due to the volatilization of isopropanol, and accordingly, this will increase the apparent SO_3 concentration. The amount of SO_2 oxidation is linearly related to the SO_2 concentration. The side reactions of SO_3 reduce the selectivity of SO_4^(2-) to nearly 73%. As sampling temperature increases from180 to 300°C, the selectivity of SO_4^(2-) decreases from 73% to 50%. The presence of H2 O in the sample gas helps to reduce the measurement error by inhibiting the volatilization of the isopropanol and weakening side reactions. A formula was established to modify the displayed value, and the measurement error was reduced from 25%–54% to less than 15%. | Jin Xiong Yuran Li Jian Wang Yang Yang Tingyu Zhu | 2018 | Journal of Environmental Sciences2018,30,10: | 6 |
| 5 | A new global land productivity dynamic product based on the consistency of various vegetation biophysical indicators显示文摘Changes in land productivity have been endorsed by the Inter Agency Expert Group on Sustainable Development Goals(IAEGSDGs)as key indicators for monitoring SDG 15.3.1.Multiple vegeta-tion parameters from optical remote sensing techniques have been widely utilized across different land productivity decline processes and scales.However,there is no consensus on indicator selection and their effectiveness at representing land productivity declining at different scales.This study proposes a fusion framework that incorporates the trends and consistencies within the four com-monly used remote sensing-based vegetation indicators.We ana-lyzed the differences among the four vegetation parameters in different land cover and climate zones,finally producing a new global land productivity dynamics(LPD)product with confidence level degrees.The LPD classes indicated by the four vegetation indicators(VIs)showed that all three levels(low,medium,and high confidence)of increasing area account for 23.99%of the global vegetated area and declining area account for 7.00%.The Increase high-confidence(HC)area accounted for 2.77%of the total area,and the Decline-HC accounted for 0.35%of the total area.This study demonstrates the accuracy of the high-confidence(HC)area for the evaluation of land productivity decline and increase.The“forest”landcover type and“humid”climate zone had the largest increasing and declining area but had the lowest high-confidence proportion.The data product provides an important and optional reference for the assessment of SDG 15.3.1 at global and regional scales according to the specific application target. | Yuran Cui Xiaosong Li | 2022 | Big Earth Data2022,6,1: | 3 |
| 6 | Coupling mechanism of activated carbon mixed with dust for flue gas desulfurization and denitrification显示文摘To clarify the effect of coking dust, sintering dust and fly ash on the activity of activated carbon for various industrial flue gas desulfurization and denitrification, the coupling mechanism of the mixed activated carbon and dust was investigated to provide theoretical reference for the stable operation. The results show that coking dust had 34% desulfurization efficiency and 10% denitrification efficiency;correspondingly, sintering dust and fly ash had no obvious desulfurization and denitrification activities. For the mixture of activated carbon and dust, the coking dust reduced the desulfurization and denitrification efficiencies by blocking the pores of activated carbon, and its inhibiting effect on activated carbon was larger than its own desulfurization and denitrification activity. The sintering dust also reduced the desulfurization efficiency on the activated carbon while enhancing the denitrification efficiency. Fly ash blocked the pores of activated carbon and reduced its reaction activity. The reaction activity of coking dust mainly came from the surface functional groups, similar to that of activated carbon. The reaction activity of sintering dust mainly came from the oxidative property of Fe_2O _3, which oxidized NO to NO_2 and promoted the fast selectively catalytic reduction(SCR) of NO to form N_2. Sintering dust was activated by the joint action of activated carbon, and both had a coupling function. Sintering dust enhanced the adsorption and oxidation of NO, and activated carbon further promoted the reduction of NO_x by NH_3;thus, the denitrification efficiency increased by 5%-7% on the activated carbon. | Junxiang Guo Yuran Li Jin Xiong Tingyu Zhu | 2020 | Journal of Environmental Sciences2020,32,12: | 2 |
| 7 | SO2 capture and attrition characteristics of CaO/bio-based sorbent显示文摘 | Li Yuran Qi Haiyan Wang Jing | 2012 | Fuel2012,93,: | 1 |
| 8 | Regulation of the differentiation of mesenchymal stem cells in vitro and osteogenesis in vivo by microenvironmental modification of titanium alloy surfaces显示文摘 | Yan Hu Kaiyong Cai Zhong Luo Yuan Zhang Liqi Li Min Lai Yanhua Hou Yuran Huang Jinghua Li Xingwei Ding Bin Zhang K.L. Paul Sung | 2012 | Biomaterials2012,,13: | 1 |
| 9 | Targeting RAS phosphorylation in cancer therapy:Mechanisms and modulators显示文摘RAS,a member of the small GTPase family,functions as a binary switch by shifting between inactive GDP-loaded and active GTP-loaded state.RAS gain-of-function mutations are one of the leading causes in human oncogenesis,accounting for w19%of the global cancer burden.As a well-recognized target in malignancy,RAS has been intensively studied in the past decades.Despite the sustained efforts,many failures occurred in the earlier exploration and resulted in an‘undruggable’feature of RAS proteins.Phosphorylation at several residues has been recently determined as regulators for wild-type and mutated RAS proteins.Therefore,the development of RAS inhibitors directly targeting the RAS mutants or towards upstream regulatory kinases supplies a novel direction for tackling the anti-RAS difficulties.A better understanding of RAS phosphorylation can contribute to future therapeutic strategies.In this review,we comprehensively summarized the current advances in RAS phosphorylation and provided mechanistic insights into the signaling transduction of associated pathways.Importantly,the preclinical and clinical success in developing anti-RAS drugs targeting the upstream kinases and potential directions of harnessing allostery to target RAS phosphorylation sites were also discussed. | Yuran Qiu Yuanhao Wang Zongtao Chai Duan Ni Xinyi Li Jun Pu Jie Chen Jian Zhang Shaoyong Lu Chuan Lv Mingfei Ji | 2021 | Acta Pharmaceutica Sinica B2021,11,11: | 1 |
| 10 | Kinetic model of CaO/fly ash sorbent for flue gas desulphurization at moderate temperatures显示文摘 | YuRan Li HaiYing Qi ChangFu You | 2007 | Fuel2007,86,56: | 1 |
| 11 | Effects of activated carbon properties on chlorobenzene adsorption and adsorption product analysis 显示文摘 | GUO Yangyang LI Yuran WANG Jian | 2014 | Chemical Engineering Journal2014,236,: | 1 |
| 12 | Atomically Dispersed Ruthenium Catalysts with Open Hollow Structure for Lithium-Oxygen Batteries显示文摘Lithium–oxygen battery with ultrahigh theoretical energy density is considered a highly competitive next-generation energy storage device,but its practical application is severely hindered by issues such as difficult decomposition of discharge products at present.Here,we have developed N-doped carbon anchored atomically dispersed Ru sites cathode catalyst with open hollow structure(h-RuNC)for Lithium–oxygen battery.On one hand,the abundance of atomically dispersed Ru sites can effectively catalyze the formation and decomposition of discharge products,thereby greatly enhancing the redox kinetics.On the other hand,the open hollow structure not only enhances the mass activity of atomically dispersed Ru sites but also improves the diffusion efficiency of catalytic molecules.Therefore,the excellent activity from atomically dispersed Ru sites and the enhanced diffusion from open hollow structure respectively improve the redox kinetics and cycling stability,ultimately achieving a high-performance lithium–oxygen battery. | Xin Chen Yu Zhang Chang Chen Huinan Li Yuran Lin Ke Yu Caiyun Nan Chen Chen | 2024 | Nano-Micro Letters2024,16,2: | 0 |
| 13 | Investigation and Analysis of Harmful Organisms Intercepted from Imported Seeds and Seedlings during 2011-2014显示文摘In this study,records published by General Administration of Quality Supervision,Inspection and Quarantine of China and related literature on harmful organisms intercepted from imported seeds and seedlings during 2011-2014 were investigated and analyzed.The results showed that the species and amount of harmful organisms intercepted from imported seeds and seedlings increased gradually during 2011-2014,which posed a realistic or potential threat to agriculture production in China.Based on the present situation,corresponding suggestions and countermeasures were proposed:1 strengthening the study on rapid detection technology of harmful organisms;2 improving the ability of animal and plant quarantine in China. | Anyu GU Xiaolin LI Yuran XU Jian HU Jinwen ZHANG Wei DENG Yonggang LU Wei NIAN Yangjun DONG Chundao YANG Jianping DUAN Zhongmin YANG | 2015 | Agricultural Biotechnology2015,4,2: | 0 |
| 14 | Visualizing the role of applied voltage in non-metal electrocatalysts显示文摘Understanding how applied voltage drives the electrocatalytic reaction at the nanoscale is a fundamental scientific problem,particularly in non-metallic electrocatalysts,due to their low intrinsic carrier concentration.Herein,using monolayer molybdenum disulfide(MoS_(2))as a model system of non-metallic catalyst,the potential drops across the basal plane of MoS_(2)(△V_(sem))and the electric double layer(△V_(edl))are decoupled quantitatively as a function of applied voltage through in-situ surface potential microscopy.We visualize the evolution of the band structure under liquid conditions and clarify the process of EF keeping moving deep into Ec,revealing the formation process of the electrolyte gating effect.Additionally,electron transfer(ET)imaging reveals that the basal plane exhibits high ET activity,consistent with the results of surface potential measurements.The potential-dependent behavior of kf and ns in the ET reaction are further decoupled based on the measurements of△V_(sem)and△V_(edl).Comparing the ET and hydrogen evolution reaction imaging results suggests that the low electrocatalytic activity of the basal plane is mainly due to the absence of active sites,rather than its electron transfer ability.This study fills an experimental gap in exploring driving forces for electrocatalysis at the nanoscale and addresses the long-standing issue of the inability to decouple charge transfer from catalytic processes. | Ziyuan Wang Jun Chen Chenwei Ni Wei Nie Dongfeng Li Na Ta Deyun Zhang Yimeng Sun Fusai Sun Qian Li Yuran Li Ruotian Chen Tiankai Bu Fengtao Fan Can Li | 2023 | National Science Review2023,10,9: | 0 |
| 15 | Multi-process and multi-pollutant control technology for ultra-low emissions in the iron and steel industry显示文摘The iron and steel industry is not only an important foundation of the national economy,but also the largest source of industrial air pollution.Due to the current status of emissions in the iron and steel industry,ultra-low pollutant emission control technology has been researched and developed.Liquid-phase proportion control technology has been developed for magnesian fluxed pellets,and a blast furnace smelting demonstration project has been established to use a high proportion of fluxed pellets(80%)for the first time in China to realize source emission reduction of SO_(2)and NO_(x).Based on the characteristics of high NO_(x)concentrations and the coexistence of multiple pollutants in coke oven flue gas,low-NO_(x)combustion coupled with multi-pollutant cooperative control technology with activated carbon was developed to achieve efficient removal of multiple pollutants and resource utilization of sulfur.Based on the characteristics of co-existing multiple pollutants in pellet flue gas,selective non-catalytic reduction(SNCR)coupled with ozone oxidation and spray drying adsorption(SDA)was developed,which significantly reduces the operating cost of the system.In the light of the high humidity and high alkalinity in flue gas,filter materials with high humidity resistance and corrosion resistance were manufactured,and an integrated pre-charged bag dust collector device was developed,which realized ultralow emission of fine particles and reduced filtration resistance and energy consumption in the system.Through source emission reduction,process control and end-treatment technologies,five demonstration projects were built,providing a full set of technical solutions for ultra-low emissions of dust,SO_(2),NO_(x),SO_(3),mercury and other pollutants,and offering technical support for the green development of the iron and steel industry. | Tingyu Zhu Xindong Wang Yong Yu Chao Li Qun Yao Yuran Li | 2023 | Journal of Environmental Sciences2023,,1: | 0 |
| 16 | A direct spino-cortical circuit bypassing the thalamus modulates nociception显示文摘Nociceptive signals are usually transmitted to layer 4 neurons in somatosensory cortex via the spinothalamic-thalamocortical pathway.The layer 5 corticospinal neurons in sensorimotor cortex are reported to receive the output of neurons in superficial layers;and their descending axons innervate the spinal cord to regulate basic sensorimotor functions.Here,we show that a subset of layer 5 neurons receives spinal inputs through a direct spino-cortical circuit bypassing the thalamus,and thus define these neurons as spino-cortical recipient neurons(SCRNs).Morphological studies revealed that the branches from spinal ascending axons formed a kind of disciform structure with the descending axons from SCRNs in the basilar pontine nucleus(BPN).Electron microscopy and calcium imaging further confirmed that the axon terminals from spinal ascending neurons and SCRNs made functional synaptic contacts in the BPN,linking the ascending sensory pathway to the descending motor control pathway.Furthermore,behavioral tests indicated that the spino-cortical connection in the BPN was involved in nociceptive responses.In vivo calcium imaging showed that SCRNs responded to peripheral noxious stimuli faster than neighboring layer 4 cortical neurons in awake mice.Manipulating activities of SCRNs could modulate nociceptive behaviors.Therefore,this direct spino-cortical circuit represents a noncanonical pathway,allowing a fast sensory-motor transition of the brain in response to noxious stimuli. | Bing Cai Dan Wu Hong Xie Yan Chen Huadong Wang Sen Jin Yuran Song Anan Li Shiqi Huang Sashuang Wang Yingjin Lu Lan Bao Fuqiang Xu Hui Gong Changlin Li Xu Zhang | 2023 | Cell Research2023,33,10: | 0 |
| 17 | HiLPD-GEE:high spatial resolution land productivity dynamicscal culation tool using Landsat and MODIS data显示文摘Land productivity is one of the sub-indicators for measuring SDG 15.3.1.Land Productivity Dynamics(LPD)is the most popular approach for reporting this indicator at the global scale.A major limitation of existing products of LPD is the coarse spatial resolution caused by remote sensing data input,which cannot meet the requirement offine-scale land degradation assessment.To resolve this problem,this study developed a tool(HiLPD-GEE)to calculate 30 m LPD by fusing Landsat and MODIS data based on Google Earth Engine(GEE).The tool generates high-quality fused Normalized Difference Vegetation Index(NDVI)dataset for LPD calculation through gapfilling and Savitzky–Golayfiltering(GF-SG)and then uses the method recommended by the European Commission Joint Research Centre(JRC)to calculate LPD.The tool can calculate 30 m LPD in any spatial range within any time window after 2013,supporting global land degradation monitoring.To demonstrate the applicability of this tool,the LPD product was produced for African Great Green Wall(GGW)countries.The analysis proves that the 30 m LPD product generated by HiLPD-GEE could reflect the land productivity change effectively and reflect more spatial details.The results also provide an important insight for the GGW initiative. | Tong Shen Xiaosong Li Yang Chen Yuran Cui Qi Lu Xiaoxia Jia Jin Chen | 2023 | International Journal of Digital Earth2023,16,1: | 0 |
| 18 | Targeting a cryptic allosteric site of SIRT6 with small-molecule inhibitors that inhibit the migration of pancreatic cancer cells显示文摘SIRT6 belongs to the conserved NAD^(+)-dependent deacetylase superfamily and mediates multiple biological and pathological processes.Targeting SIRT6 by allosteric modulators represents a novel direction for therapeutics,which can overcome the selectivity problem caused by the structural similarity of orthosteric sites among deacetylases.Here,developing a reversed allosteric strategy Allo Reverse,we identified a cryptic allosteric site,Pocket Z,which was only induced by the bi-directional allosteric signal triggered upon orthosteric binding of NAD^(+).Based on Pocket Z,we discovered an SIRT6 allosteric inhibitor named JYQ-42.JYQ-42 selectively targets SIRT6 among other histone deacetylases and effectively inhibits SIRT6 deacetylation,with an IC50 of 2.33μmol/L.JYQ-42 significantly suppresses SIRT6-mediated cancer cell migration and pro-inflammatory cytokine production.JYQ-42,to our knowledge,is the most potent and selective allosteric SIRT6 inhibitor.This study provides a novel strategy for allosteric drug design and will help in the challenging development of therapeutic agents that can selectively bind SIRT6. | Qiufen Zhang Yingyi Chen Duan Ni Zhimin Huang Jiacheng Wei Li Feng Jun-Cheng Su Yingqing Wei Shaobo Ning Xiuyan Yang Mingzhu Zhao Yuran Qiu Kun Song Zhengtian Yu Jianrong Xu Xinyi Li Houwen Lin Shaoyong Lu Jian Zhang | 2022 | Acta Pharmaceutica Sinica B2022,12,2: | 0 |
| 19 | Analysis on the Breeding and Major Traits of Wide-adaptability Indica CMS Line Yungu 3A显示文摘Breeding sterile lines is the key to the development of hybrid rice with wide adaptability. However,at present,few wide-adaptability sterile lines have been applied in production practice. In this study,Yungu 3A,a new WA-type Indica CMS line with good grain quality,was developed by hybridization between Yunfeng 66 A with wide adaptability as female parent and F1 plants of Yunfeng 66 B / D62 B as male parent and continuous backcrossing. According to the results,the finally obtained Indica CMS line Yungu 3A has good plant type and leaf shape,strong tillering ability,excellent flowering habit,stable and complete male sterility with the sterile plant rate and pollen sterility rate of 100%,strong combining ability,high outcrossing rate,low sensitivity to light and temperature,and strong disease resistance,which was approved by Yunnan Provincial Crop Variety Appraisal Committee in 2013. Yungu 3A is conducive to the development of new hybrid rice combinations with good quality and wide adaptability,exhibiting a promising prospect of application. | Yonggang LU Huafeng DENG Jinwen ZHANG Wei DENG Yuran XU Anyu GU Wei NIAN Zhiliang LU Xiaolin LI | 2015 | Agricultural Biotechnology2015,4,3: | 0 |