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| 1 | Trend analysis of cancer incidence and mortality in China显示文摘The National Central Cancer Registry of China(NCCRC)updated their nationwide statistics of cancer incidence and mortality in China according to 2013 population-based cancer registration data(due to the time required for data collection,quality control and analysis,the latest cancer statistics available in China have a 3-year lag behind the current year).In this report,the NCCRC provides a comprehensive review of cancer incidence and mortality rates,as well as the statistics overall and by geographical area,cancer sites or age groups(Chen et al.,2017a).It shows that the burden of cancer | Fang Wei Yingfen Wu Le Tang Fang Xiong Can Guo Xiayu Li Ming Zhou Bo Xiang Xiaoling Li Guiyuan Li Wei Xiong Zhaoyang Zeng | 2017 | Science China(Life Sciences)2017，60，11： | 16 |
| 2 | Polysaccharide extracts of Astragalus membranaceus and Atractylodes macrocephala promote intestinal epithelial cell migration by activating the polyamine-mediated K^+ channel显示文摘Astragalus membranaceus(Radix Astragali, RA) and Atractylodes macrocephala(Rhizoma Atractylodis Macrocephalae, RAM) are often used to treat gastrointestinal diseases. In the present study, we determined the effects of polysaccharides extracts from these two herbs on IEC-6 cell migration and explored the potential underlying mechanisms. A migration model with IEC-6 cells was induced using a single-edged razor blade along the diameter of cell layers in six-well polystyrene plates. The cells were grown in control--media or media containing spermidine(5 μmol·L^(-1), SPD), alpha-difluoromethylornithine(2.5 mmol·L^(-1), DFMO), 4-Aminopyridine-(40 μ-mol·L^(-1), 4-AP), the polysaccharide extracts of RA or RAM(50, 100, or 200 mg·L^(-1)), DFMO plus SPD, or DFMO plus polysaccharide extracts of RA or RAM for 12 or 24 h. Next, cytosolic free Ca^(2+)([Ca^(2+)]cyt) was measured using laser confocal microscopy, and cellular polyamine content was quantified with HPLC. Kv1.1 mRNA expression was assessed using RT-qPCR and Kv1.1 and RhoA protein expressions were measured with Western blotting analysis. A cell migration assay was carried out using Image-Pro Plus software. In addition, GC-MS was introduced to analyze the monosaccharide composition of both polysaccharide extracts. The resutls showed that treatment with polysaccharide extracts of RA or RAM significantly increased cellular polyamine content, elevated [Ca^(2+)]cyt and accelerated migration of IEC-6 cells, compared with the controls(P < 0.01). Polysaccharide extracts not only reversed the inhibitory effects of DFMO on cellular polyamine content and [Ca^(2+)]cyt, but also restored IEC-6 cell migration to control level(P < 0.01 or < 0.05). Kv1.1 mRNA and protein expressions were increased(P < 0.05) after polysaccharide extract treatment in polyamine-deficient IEC-6 cells and RhoA protein expression was increased. Molar ratios of D-ribose, D-arabinose, L-rhamnose, D-mannose, D-glucose, and D-galactose was 1.0:14.1:0.3:19.9:181.3:6.3 in RA and 1.0:4.3:0.1:5.7:2.8:2.2 in RAM. In conclusion, treatment with RA and RAM polysaccharide extracts stimulated migration of intestinal epithelial cells via a polyamine-Kv1.1 channel activated signaling pathway, which facilitated intestinal injury healing. | ZENG Dan HU Can LI Ru-Liu LIN Chuan-Quan CAI Jia-Zhong WU Ting-Ting SUI Jing-Jing LU Wen-Biao CHEN Wei-Wen | 2018 | Chinese Journal of Natural Medicines2018，16，9： | 14 |
| 3 | Dynamic changes of behaviors, dentate gyrus neurogenesis and hippocampal miR-124 expression in rats with depression induced by chronic unpredictable mild stress显示文摘The depression-like behavior phenotype,neurogenesis in the dentate gyrus and miR-124 expression in the hippocampus are the focus of current research on the pathogenesis of depression and antidepressant therapy.The present study aimed to clarify the dynamic changes of depression-like behavior,dentate gyrus neurogenesis and hippocampal miR-124 expression during depression induced by chronic stress to reveal pathological features at different stages of depression and to further provide insight into depression treatment.Chronic unpredictable mild stress depression models were established by exposing Sprague-Dawley rats to various mild stressors,including white noise,thermal swimming,stroboscopic illumination,soiled cages,pairing with three other stressed animals,cold swimming,tail pinch,restraint and water and food deprivation.Chronic unpredictable mild stress model rats underwent dynamic observation from 1 to 8 weeks and were compared with a control group(normal feeding without any stressors).To observe changes in the depression-like behavior phenotype during chronic unpredictable mild stress-induced depression,a sucrose preference test was used to evaluate the degree of anhedonia.An open-field test was used to evaluate locomotor activity and anxiety status.Compared with the control group,chronic unpredictable mild stress rats lost weight but did not have a depression-like behavioral phenotype at 1-4 weeks.Chronic unpredictable mild stress rats presented decreased sucrose preference and locomotor activity at 5-8 weeks.In addition,chronic unpredictable mild stress rats did not have significant anxiety-like behavior during 1-8 weeks of modeling.To observe neurogenesis dysfunctions and changes in neuronal number in the dentate gyrus during chronic unpredictable mild stress-induced depression,markers(DCX and DCX/BrdU)of neural proliferation and differentiation and the neuronal marker NeuN were assessed by immunofluorescence.Compared with the control group,neurogenesis and the neuronal number in the dentate gyrus did not change from 2 to 6 weeks;however,neural proliferation and differentiation in the dentate gyrus decreased,and the number of neurons decreased until the eighth week in the chronic unpredictable mild stress group.Real-time quantitative reverse transcription polymerase chain reaction assays and fluorescence in situ hybridization were used to measure the expression of hippocampal miR-124 during chronic unpredictable mild stress-induced depression.The results showed that the expression of hippocampal miR-124 was unchanged during the first 4 weeks but increased from 5 to 6 weeks and decreased from 7 to 8 weeks compared with the control group.These findings indicate that during chronic unpredictable mild stress-induced depression,the behavioral phenotype,miR-124 expression in the hippocampus,neurogenesis in the dentate gyrus and neuronal numbers showed dynamic changes,which suggested that various pathological changes occur at different stages of depression.All experimental procedures and protocols were approved by the Experimental Animal Ethics Committee of Guangzhou University of Chinese Medicine of China in March 2015. | Yun-Ling Huang Ning-Xi Zeng Jie Chen Jie Niu Wu-Long Luo Ping Liu Can Yan Li-Li Wu | 2020 | Neural Regeneration Research2020，15，6： | 10 |
| 4 | Hic74,a novel alanine and glycine rich matrix protein related to nacreous layer formation in the mollusc Hyriopsis cumingii显示文摘Organic matrix proteins play an important role in the biomineralization of mollusc shells.We have identified and characterized a novel matrix protein,namely hic74,isolated from the mantle of the freshwater mussel Hyriopsis cumingii.The hic74 gene encodes a 850 amino acid protein that is rich in alanine(ala,30.8%),glycine(gly,25.8%)and serine(ser,10.6%),with ala mainly existing in poly-ala forms within the ala/gly-rich regions.Quantitative PCR expression analysis demonstrated that hic74 was specifically amplified from the mantle and in situ hybridization showed a strong signal in the epithelial cells in the pallial region of the mantle.Lower levels of expression were detected during the early stages of pearl sac formation but increased and remained constant during nacreous layer formation suggesting that hic74 might be involved in this process. | Xiaojun Liu Can Jin Leiming Wu Shaojian Dong Shimei Zeng Jiale Li | 2017 | Aquaculture and Fisheries2017，2，3： | 6 |
| 5 | Single metal atom decorated photocatalysts:Progress and challenges显示文摘Photocatalysis has attracted intense attention due to its potential to solve the energy resource problem and environmental issues.The single metal atom decorated photocatalysts as a rising star become more and more popular because of the unique advantages of superior catalytic activities and ultrahigh atom utilization efficiency.The key function of single metal atom catalysts in photocatalytic reactions is boosting surface redox reactions by utilizing photogenerated charges,and has been verified by various spectroscopic and microscopic techniques.Nevertheless,the activities of the single metal atoms highly depend on the binding environment in the host photocatalyst that affect the adsorption and activation of reactants as well as the reaction energy barrier.Herein,this mini review summarizes recent progress on single metal atom decorated photocatalysts,and discusses the roles of the single metal atom catalysts in different types of host photocatalysts including organic,carbon-based and inorganic materials.The remaining challenges and future perspectives on the stability and activities of single atom catalysts in photocatalytic processes are elaborated in the end.We believe that this mini review will provide valuable overview on synthetic methods of different single atom photocatalysts for researchers towards future development of highly efficient photocatalysts. | Lei Zeng Can Xue | 2021 | Nano Research2021，14，4： | 5 |
| 6 | Overview and countermeasures of cancer burden in China显示文摘Cancer is one of the leading causes of human death worldwide.Treatment of cancer exhausts significant medical resources,and the morbidity and mortality caused by cancer is a huge social burden.Cancer has therefore become a serious economic and social problem shared globally.As an increasingly prevalent disease in China,cancer is a huge challenge for the country’s healthcare system.Based on recent data published in the Journal of the National Cancer Center on cancer incidence and mortality in China in 2016,we analyzed the current trends in cancer incidence and changes in cancer mortality and survival rate in China.And also,we examined several key risk factors for cancer pathogenesis and discussed potential countermeasures for cancer prevention and treatment in China. | Yian Wang Qijia Yan Chunmei Fan Yongzhen Mo Yumin Wang Xiayu Li Qianjin Liao Can Guo Guiyuan Li Zhaoyang Zeng Wei Xiong He Huang | 2023 | Science China(Life Sciences)2023，66，11： | 5 |
| 7 | Exploration of the mechanism by which icariin modulates hippocampal neurogenesis in a rat model of depression显示文摘Icariin(ICA) has a significant capacity to protect against depression and hippocampal injury,but it cannot effectively cross the bloodbrain barrier and accumulate in the brain.Therefore,the mechanism by which ICA protects against hippocampal injury in depression remains unclear.In this study,we performed proteomics analysis of cerebrospinal fluid to investigate the mechanism by which ICA prevents dysfunctional hippocampal neurogenesis in depression.A rat model of depression was established through exposure to chronic unpredictable mild stress for 6 weeks,after which 120 mg/kg ICA was administered subcutaneously every day.The results showed that ICA alleviated depressive symptoms,learning and memory dysfunction,dysfunctional neurogenesis,and neuronal loss in the dentate gyrus of rats with depression.Neural stem cells from rat embryonic hippocampi were cultured in media containing 20% cerebrospinal fluid from each group of rats and then treated with 100 μM corticosterone.The addition of cerebrospinal fluid from rats treated with ICA largely prevented the corticosterone-mediated inhibition of neuronal proliferation and differentiation.Fifty-two differentially expressed proteins regulated by chronic unpredictable mild stress and ICA were identified through proteomics analysis of cerebrospinal fluid.These proteins were mainly involved in the ribosome,PI3 K-Akt signaling,and interleukin-17 signaling pathways.Parallel reaction monitoring mass spectrometry showed that Rps4 x,Rps12,Rps14,Rps19,Hsp90 b1,and Hsp90 aa1 were up-regulated by chronic unpredictable mild stress and down-regulated by ICA.In contrast,Htr A1 was down-regulated by chronic unpredictable mild stress and up-regulated by ICA.These findings suggest that ICA can prevent depression and dysfunctional hippocampal neurogenesis through regulating the expression of certain proteins found in the cerebrospinal fluid.The study was approved by the Experimental Animal Ethics Committee of Guangzhou University of Chinese Medicine of China in March 2017. | Ning-Xi Zeng Hui-Zhen Li Han-Zhang Wang Kai-Ge Liu Xia-Yu Gong Wu-Long Luo Can Yan Li-Li Wu | 2022 | Neural Regeneration Research2022，17，3： | 4 |
| 8 | AFAP1-AS1: a rising star among oncogenic long non-coding RNAs显示文摘Long non-coding RNAs(lncRNAs)have become a hotspot in biomedical research.This interest reflects their extensive involvement in the regulation of the expression of other genes,and their influence on the occurrence and development of a variety of human diseases.Actin filament associated protein 1-Antisense RNA 1(AFAP1-AS1)is a recently discovered oncogenic lncRNA.It is highly expressed in a variety of solid tumors,and regulates the expression of downstream genes and signaling pathways through adsorption and competing microRNAs,or by the direct binding to other proteins.Ultimately,AFAP1-AS1 promotes proliferation,chemotherapy resistance,and resistance to apoptosis,maintains stemness,and enhances invasion and migration of tumor cells.This paper summarizes the research concerning AFAP1-AS1 in malignant tumors,including the clinical application prospects of AFAP1-AS1 as a potential molecular marker and therapeutic target of malignant tumors.We also discuss the limitations in the knowledge of AFAP1-AS1 and directions of further research.AFAP1-AS1 is expected to provide an example for studies of other lncRNA molecules. | Fang Xiong Kunjie Zhu Su Deng Hongbin Huang Liting Yang Zhaojian Gong Lei Shi Yi He Yanyan Tang Qianjin Liao Jianjun Yu Xiaoling Li Yong Li Guiyuan Li Zhaoyang Zeng Wei Xiong Shanshan Zhang Can Guo | 2021 | Science China(Life Sciences)2021，64，10： | 4 |
| 9 | CBLN2 rs2217560 was Associated with Pulmonary Arteria Hypertension in Systemic Lupus Erythematosus显示文摘To the Editor:Pulmonary arterial hypertension (PAH)is a hemodynamic disorder with elevated pressure of pulmonary circulation.Genetic studies in familial PAH (fPAH)and idiopathic PAH (iPAH)have discovered that transforming growth factor-β (TGF-β) superfamily plays an important role,and the identified mutations occur in bone morphogenetic protein type 2 receptor (BMPR2), activin receptor-like kinase type 1 (ALK1),Endoglin,and SMAD9. A genome-wide association study (GWAS)in patients without BMPR2 mutations discovered that one single-nucleotide polymorphism (SNP)rs2217560 had a significant association with i/fPAH,which located 52-kb downstream of the CBLN2 gene. | Can Huang Jun Yang Meng-Tao Li Qian Wang Jiu-Liang Zhao Xiao-Xi Yang Zhuang Tian Yong-Tai Liu Xiao-Xiao Guo Hui Wang Jin-Zhi Lai Yan-Jiang Xing Xiao-Feng Zeng | 2018 | Chinese Medical Journal2018，，24： | 4 |
| 10 | Circular RNA circCCNB1 inhibits the migration and invasion of nasopharyngeal carcinoma through binding and stabilizing TJP1 mRNA显示文摘Nasopharyngeal carcinoma(NPC)is a malignant tumor that usually occurs in people from Southeast Asia and Southern China.NPC is prone to migration and invasion,leading to poor prognosis.A large number of circular RNAs(circ RNAs)exacerbate the process of metastasis in NPC;however,their underlying mechanisms remain unclear.We found that the circular RNA circ CCNB1,encoded by the oncogene CCNB1,was downregulated in NPC biopsies and cell lines.In vitro assays show that circ CCNB1 inhibits NPC cell migration and invasion.Moreover,circ CCNB1 induces a protein,nuclear factor 90(NF90),to bind and prolong the half-life of tight junction protein 1(TJP1)m RNA.Upregulation of TJP1 enhances tight junctions between cancer cells and inhibits NPC cell migration and invasion.This study reveals a novel biological function of circ CCNB1 in the migration and invasion of NPC by enhancing the tight junctions of cancer cells by binding to NF90 proteins and TJP1 m RNA,and may provide a potential therapeutic target for NPC. | Mengyao Zhao Yian Wang Fenghua Tan Lingyun Liu Xiangchan Hou Chunmei Fan Le Tang Yongzhen Mo Yumin Wang Qijia Yan Zhaojian Gong Zheng Li Qianjin Liao Can Guo He Huang Xi Zeng Guiyuan Li Zhaoyang Zeng Wei Xiong Fuyan Wang | 2022 | Science China(Life Sciences)2022，65，11： | 4 |
| 11 | Effects and mechanisms of innate immune molecules on inhibiting nasopharyngeal carcinoma显示文摘To the Editor: The nasopharyngeal ep让helium is frequently exposed to various harmful carcinogens. When the nasopharvngeal mucosa is damaged, local inflammation is induced.[1] Chronic inflammation of the nasopharyngeal epithelium may eventually evolve into nasopharyngeal carcinoma (NPC). While the mucus secreted by the nasopharyngeal epithelium forms the body's primitive immune protection barrier as it contains a series of proteins and peptides that can sense, bind, degrade and remove various harmful substances. Lactotransferrin (LTF)[2] and bactericidal/permeability-increasing (BPI) protein family members[3] are an important component of the innate immune protection barrier. | Fang Xiong Su Deng Hong-Bin Huang Xia-Yu Li Wen-Ling Zhang Qian-Jin Liao Jian Ma Xiao-Ling Li Wei Xiong Gui-Yuan Li Zhao-Yang Zeng Can Guo | 2019 | Chinese Medical Journal2019，，6： | 3 |
| 12 | A male-ABCD algorithm for hepatocellular carcinoma risk prediction in HBs Ag carriers显示文摘Objective: Hepatocellular carcinoma(HCC) development among hepatitis B surface antigen(HBs Ag) carriers shows gender disparity, influenced by underlying liver diseases that display variations in laboratory tests. We aimed to construct a risk-stratified HCC prediction model for HBs Ag-positive male adults.Methods: HBs Ag-positive males of 35-69 years old(N=6,153) were included from a multi-center populationbased liver cancer screening study. Randomly, three centers were set as training, the other three centers as validation. Within 2 years since initiation, we administrated at least two rounds of HCC screening using Bultrasonography and α-fetoprotein(AFP). We used logistic regression models to determine potential risk factors,built and examined the operating characteristics of a point-based algorithm for HCC risk prediction.Results: With 2 years of follow-up, 302 HCC cases were diagnosed. A male-ABCD algorithm was constructed including participant's age, blood levels of GGT(γ-glutamyl-transpeptidase), counts of platelets, white cells,concentration of DCP(des-γ-carboxy-prothrombin) and AFP, with scores ranging from 0 to 18.3. The area under receiver operating characteristic was 0.91(0.90-0.93), larger than existing models. At 1.5 points of risk score,26.10% of the participants in training cohort and 14.94% in validation cohort were recognized at low risk, with sensitivity of identifying HCC remained 100%. At 2.5 points, 46.51% of the participants in training cohort and 33.68% in validation cohort were recognized at low risk with 99.06% and 97.78% of sensitivity, respectively. At 4.5 points, only 20.86% of participants in training cohort and 23.73% in validation cohort were recognized at high risk,with positive prediction value of 22.85% and 12.35%, respectively.Conclusions: Male-ABCD algorithm identified individual's risk for HCC occurrence within short term for their HCC precision surveillance. | Yuting Wang Minjie Wang He Li Kun Chen Hongmei Zeng Xinyu Bi Zheng Zhu Yuchen Jiao Yong Wang Jian Zhu Hui Zhao Xiang Liu Chunyun Dai Chunsun Fan Can Zhao Deyin Guo Hong Zhao Jianguo Zhou Dongmei Wang Zhiyuan Wu Xinming Zhao Wei Cui Xuehong Zhang Jianqiang Cai Wanqing Chen Chunfeng Qu | 2021 | Chinese Journal of Cancer Research2021，33，3： | 3 |
| 13 | MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways显示文摘 | Longlong Bao Yan Yan Can Xu Weidan Ji Shuwen Shen Gaoya Xu Yong Zeng Bin Sun Haihua Qian Lei Chen Mengchao Wu Changqing Su Jie Chen | 2013 | Cancer Letters2013，，2： | 3 |
| 14 | Increased 5-hydroxymethylcytosine and Ten-eleven Translocation Protein Expression in Ultraviolet B-irradiated HaCaT Cells显示文摘 | Dan Wang Jin-Hua Huang Qing-Hai Zeng Can Gu Shu Ding Jian-Yun Lu Jing Chen Sheng-Bo Yang | 2017 | Chinese Medical Journal2017，，5： | 2 |
| 15 | Trend of technology innovation in China’s coal-fired electricity industry under resource and environmental constraints显示文摘 | Fanxian Yu Jining Chen Fu Sun Siyu Zeng Can Wang | 2010 | Energy Policy2010，，3： | 1 |
| 16 | Secure Localization and Location Verification in Wireless Sensor Networks: A Survey显示文摘 | Zeng Yingpei Can Jiannong Xie Li | 2013 | Journal of Supercomputing2013，64，3： | 1 |
| 17 | MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways显示文摘 | Longlong Bao Yan Yan Can Xu Weidan Ji Shuwen Shen Gaoya Xu Yong Zeng Bin Sun Haihua Qian Lei Chen Mengchao Wu Changqing Su Jie Chen | 2013 | Cancer Letters2013，，2： | 1 |
| 18 | First Report in China on the Identification and Drug Sensitivity of Mycobacterium elephantis Isolated from the Milk of a Cow with Mastitis显示文摘Objective In this study, milk from a cow with mastitis was analyzed to determine the presence of mycobacterial infection. Milk quality and security problems pertaining to the safe consumption of dairy products were also discussed in this study. Methods Milk was preprocessed with 4% Na OH. Then, mycobacteria were isolated from the milk sample on L-J medium. The isolate was identified using multiple loci Polymerase Chain Reaction(PCR) and multi-locus sequence analysis with 16 S r RNA, sod A, hsp65, and ITS genes. The drug sensitivity of the isolate to 27 antibiotics was tested through alamar blue assay. Results Smooth, moist, pale yellow colonies appeared on the L-J medium within a week after inoculation. Based on the results of multiple loci PCR analysis, the isolate was preliminarily identified as non-tuberculous mycobacteria. The 16 S r RNA, Sod A, hsp65, and ITS gene sequences of the isolate exhibited 99%, 99%, 99%, and 100% similarities, respectively, with those of the published reference strains of Mycobacterium elephantis(M. elephantis). The drug sensitivity results showed that the strain is resistant to isoniazid, p-aminosalicylic acid, and trimesulf but is sensitive to ofloxacin, rifampicin, amikacin, capreomycin, moxifloxacin, kanamycin, levofloxacin, cycloserine, ethambutol, streptomycin, tobramycin, rifabutin, ciprofloxacin, linezolid, cefoxitin, clarithromycin, and minocycline. Conclusion To the best of our knowledge, this study is initially to report the isolation of M. elephantis from the milk of a cow with mastitis in China. | JI Ling Yun XU Dong Lei YIN Shu Peng LIU Hai Can LI Gui Lian JIANG Yi WEI Jian Hao ZENG Hao LOU Yong Liang LYU Jian Xin WAN Kang Lin | 2017 | Biomedical and Environmental Sciences2017，30，7： | 1 |
| 19 | The promotion of endothelial progenitor cells recruitment by nerve growth factors in tissue-engineered blood vessels显示文摘 | Wen Zeng Wei Yuan Li Li Jianhong Mi Shangcheng Xu Can Wen Zhenhua Zhou Jiaqiang xiong Jiansen Sun Dajun Ying Mingcan Yang Xiaosong Li Chuhong Zhu | 2009 | Biomaterials2009，，7： | 1 |
| 20 | In situ generated layered NiFe-LDH/MOF heterostructure nanosheet arrays with abundant defects for efficient alkaline and seawater oxidation显示文摘As the main limiting step of overall water splitting,oxygen evolution reaction(OER)is urgent to be enhanced by developing efficient catalysts to promote the process of electrolytic water.Based on theoretical analysis,the Ni-metal-organic framework(Ni-MOF)and NiFe-layered double hydroxide(NiFe-LDH)(NiFe-LDH/MOF)heterostructure can optimize the energy barrier of the OER process and decrease the adsorption energy of oxygen-containing intermediates,effectively accelerating the OER kinetics.Accordingly,layered NiFe-LDH/MOF heterostructures are in situ constructed through a facile two-step reaction process,with substantial oxygen defects and lattice defects that further improve the catalytic performance.As a result,only 208 and 275 mV OER overpotentials are needed for NiFe-LDH/MOF to drive the current densities of 20 and 100 mA·cm^(-2)in 1 M KOH solutions,and even maintain catalytic stability of 100 h at 20 mA·cm^(-2).When applied to seawater oxidation,only 235 and 307 mV OER overpotentials are required to achieve the current densities of 20 and 100 mA·cm^(-2),respectively,with almost no attenuation for 100 h stability test at 20 mA·cm^(-2),all better than commercial RuO_(2).This work provides the theoretical and experimental basis and a new idea for efficiently driving fresh water and seawater cracking by heterostructure and defect coupling design toward catalysts. | Manjie Xiao Can Wu Jiawei Zhu Chengtian Zhang Yan Li Jiahui Lyu Weihao Zeng Haiwen Li Lei Chen Shichun Mu | 2023 | Nano Research2023，16，7： | 1 |
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