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| 1 | Growth and characterization of 2-inch high quality β-Ga2O3 single crystals grown by EFG method显示文摘β-Ga_2O_3 is an ultra-wide band-gap semiconductor with promising applications in UV optical detectors,Schottky barrier diodes, field-effect transistors and substrates for light-emitting diodes. However, the preparation of large β-Ga_2O_3 crystals is undeveloped and many properties of this material have not been discovered yet. In this work, 2-inch β-Ga_2O_3 single crystals were grown by using an edge-defined film-fed growth method. The high quality of the crystal has been proved by high-resolution X-ray diffraction with 19.06 arcsec of the full width at half maximum. The electrical properties and optical properties of both the unintentionally doped and Si-doped β-Ga_2O_3 crystals were investigated systematically. | Shengnan Zhang Xiaozheng Lian Yanchao Ma Weidan Liu Yingwu Zhang Yongkuan Xu Hongjuan Cheng | 2018 | Journal of Semiconductors2018，39，8： | 12 |
| 2 | Degradation and biological properties of Ca-P contained micro-arc oxidation self-sealing coating on pure magnesium for bone fixation显示文摘Poor corrosion resistance is one of the main disadvantages for biodegradable magnesium-based metals,especially applied for bone fixation,where there is a high demand of bio-mechanical strength and stability.Surface coating has been proved as an effective method to control the in vivo degradation.In this study a Ca-P self-sealing micro-arc oxidation(MAO)coating was studied to verify its efficacy and biological properties by in vitro and in vivo tests.It was found that the MAO coating could effectively retard the degradation according to immersion and electrochemical tests as well as 3D reconstruction by X-ray tomography after implantation.The MAO coating exhibited no toxicity and could stimulate the new bone formation.Therefore,the Ca-P self-sealing MAO coating could be a potential candidate for application of biodegradable Mg-based implant in bone fixations. | Weidan Wang Peng Wan Chen Liu Lili Tan Weirong Li Lugee Li Ke Yang | 2015 | Regenerative Biomaterials2015，2，2： | 11 |
| 3 | The Cambrian sedimentary characteristics and their implications for oil and gas exploration in north margin of Middle-Upper Yangtze Plate显示文摘Using data from tens of measured and observed outcrop successions,thin rock slices and sample analyses,we comprehensively studied the Cambrian sedimentary environments and evolutionary characteristics in the north margin of the Middle-Upper Yangtze Plate.During the Cambrian,platform,slope,and deep sea basin environments were developed in the study area.On the platform,both clastic rocks and carbonate rocks were deposited.Clastic rocks mainly occur in the Lower Cambrian,and were deposited in marine shore and shelf environments.Carbonate rocks are dominant in the Middle and Upper Cambrian,and were deposited in the open platform,restricted platform,tidal flat,beach,and reef environments.Carbonate gravity flow deposits were developed on the slope.In the basin,mainly black shales and chert beds were deposited.The Cambrian represents one large transgression-regression cycle,and maximum transgression occurred in the Qiongzhusi Age of the Early Cambrian.Tectonics and sea level fluctuations had important impacts on sedimentary environments.The Chengkou-Fangxian-Xiangfan Fracture controlled the position of the platform,slope and basin,as well as the silica supply for chert deposition in basin.Sea level fluctuations controlled types of sediments and sedimentary facies on the platform.In the study area,there are good reservoir rocks,including dolomites,grainstones,debris flow deposits,sandstones,and conglomerates;there are good source rocks,including black shales,dark micrites,and chert beds;and there are also good reservoir-source rock assemblages.The hydrocarbon potential of the study area is great. | YU KuanHong JIN ZhenKui SU Kui DONG XiaoDong ZHANG Wei DU HongYu CHEN Ying ZHANG WeiDan | 2013 | Science China Earth Sciences2013，56，6： | 9 |
| 4 | The influence of graded levels of available phosphorus on growth performance,muscle antioxidant and flesh quality of young grass carp(Ctenopharyngodon idella)显示文摘Growth, muscle composition, meat quality characteristics and antioxidant capacity in muscle of young grass carp(Ctenopharyngodon idella)(initial weight 282.9 ± 3.3 g) fed graded levels of phosphorus(1.0,2.5, 3.8, 5.6, 7.8 and 9.5 g/kg diet) for 8 wk were investigated. Results indicated that percentage weight gain, feed intake, feed efficiency, serum phosphorus and alkaline phosphatase were improved with optimal phosphorus supplementations(P < 0.05). Muscle protein content and water holding capacity were significantly elevated, while moisture, lipid and ash contents were significantly decreased with dietary phosphorus to a certain level(P < 0.05). The meat shear force value and hydroxyproline content were not influenced by different levels of phosphorus. Muscle anti-hydroxyl radical, superoxide dismutase, catalase, glutathione S-transferase activities and glutathione content were significantly improved(P < 0.05). Conversely, anti-superoxide anion, glutathione reducase and glutathione peroxidase activities were decreased(P < 0.05) with dietary phosphorus to a certain level. These results indicated that suitable dietary phosphorus improved growth performance, meat quality and muscle antioxidant capacity. Dietary available phosphorus requirement of young grass carp for percentage weight gain was4.0 g/kg diet. | Jing Wen Weidan Jiang Lin Feng Shengyao Kuang Jun Jiang Ling Tang Xiaoqiu Zhou Yang Liu | 2015 | Animal Nutrition2015，，2： | 8 |
| 5 | Synergistic antitumor effect of TRAIL and IL-24 with complete eradication of hepatoma in the CTGVT-DG strategy显示文摘ZD55 肿瘤坏死因素相关的导致 apoptosis ligand (小道) 和 ZD55-interleukin (IL )-24 被独立把小道或 IL-24 基因插入到侵入人体气管粘膜的病菌说出 ZD55 的 oncolytic 构造(与侵入人体气管粘膜的病菌 E1B-55kD 删除) 。产生 ZD55 小道和 ZD55-IL-24 在联合被使用在老鼠建模的裸体治疗异种皮移植肿瘤。结果证明它不能仅仅完全消除 BEL7404 hepatoma 异种皮移植而且对 gaster,肺,前列腺,和胸癌有优秀 antitumor 效果。ZD55 小道不能仅仅压制在更低的剂量由 ZD55-IL-24 支持效果的肿瘤生长,这也被发现,而且实质地在他们的联合使用减少癌症细胞生存能力。这是因为 ZD55-IL-24 和 ZD55 小道能互相极大地提高对方的 antitumor 效果。所有这些调查结果显著地显示出小道和 IL-24 的 synergistic antitumor 效果,它也在 vivo 在 vitro 并且也是为由小道和 IL-24 的联合使用的 antitumor 效果的原因。 | Ying Cai Xinran Liu Weidan Huang Kangjian Zhang Xin-Yuan Liu | 2012 | Acta Biochimica et Biophysica Sinica2012，44，6： | 6 |
| 6 | The relationship between dietary methionine and growth,digestion,absorption,and antioxidant status in intestinal and hepatopancreatic tissues of sub-adult grass carp(Ctenopharyngodon idella)显示文摘Background: Methionine is an essential amino acid for fish. The present study was conducted to investigate the effects of dietary methionine on growth performance, digestive and absorptive ability, as well as antioxidant capacity in the intestine and hepatopancreas of sub-adult grass carp(Ctenopharyngodon idella).Results: Dietary methionine deficiency significantly decreased percentage weight gain(PWG), feed intake, feed efficiency and protein efficiency ratio, as well as activities of hepatopancreatic glutamate-oxaloacetate transaminase and muscle glutamate-pyruvate transaminase in sub-adult grass carp(P < 0.05). Furthermore, methionine deficiency significantly reduced activities of trypsin, lipase and amylase in the intestine, Na^+/K^+-ATPase, alkaline phosphatase and γ-glutamyl transpeptidase in three intestinal segments, and creatine kinase(CK) in the proximal intestine(P < 0.05). However, an unexplained and significant increase in CK activity in the mid intestine was associated with dietary methionine deficiency. Malondialdehyde and protein carbonyl contents in the intestine and hepatopancreas were significantly increased by methionine deficiency(P < 0.05), whereas anti-hydroxyl radical capacity in the hepatopancreas and intestine, and anti-superoxide anion capacity in the intestine, were significantly decreased by methionine deficiency(P < 0.05). Moreover, methionine deficiency significantly decreased superoxide dismutase and glutathione reductase activities, glutathione contents in the hepatopancreas and intestine, as well as glutathione peroxidase activity in the intestine(P < 0.05), whereas it significantly increased activities of catalase in the hepatopancreas and glutathione-S-transferase in the hepatopancreas and intestine(P < 0.05).(Continued on next page)(Continued from previous page)Conclusions: The present results demonstrated that dietary methionine deficiency induced poor growth, and decreased digestive and absorptive function and antioxidant capacity in the hepatopancreas and intestine of sub-adult grass carp. Methionine requirements for sub-adult grass carp(450-1, 170 g) based on PWG, intestinal trypsin, and hepatopancreatic anti-hydroxyl radical activities were estimated to be 6.12 g/kg diet(21.80 g/kg protein),6.99 g/kg diet(24.90 g/kg protein) and 5.42 g/kg diet(19.31 g/kg protein), respectively, in the presence of 1.50 g cysteine/kg(5.35 g/kg protein). | Pei Wu Ling Tang Weidan Jiang Kai Hu Yang Liu Jun Jiang Shengyao Kuang ling tang Wuneng Tang Yongan Zhang Xiaoqiu Zhou Lin Feng | 2017 | Journal of Animal Science and Biotechnology2017，8，4： | 4 |
| 7 | MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways显示文摘 | Longlong Bao Yan Yan Can Xu Weidan Ji Shuwen Shen Gaoya Xu Yong Zeng Bin Sun Haihua Qian Lei Chen Mengchao Wu Changqing Su Jie Chen | 2013 | Cancer Letters2013，，2： | 3 |
| 8 | Phase growth patterns for Al_(2)O_(3)/GdAlO_(3)eutectics over wide ranges of compositions and solidification rates显示文摘Phase selection and growth characteristics of directionally solidified Al_(2)O_(3)/GdAlO_3(GAP)faceted eutectic ce ramics are investigated over wide ranges of compositions and solidification rates to explore the eutectic coupled zone.Through the obse rvation of the quenched solid-liquid interface,the competitive growth of primary faceted Al_(2)O_(3)phase,prima ry non-faceted GAP phase and Al_(2)O_(3)/GAP eutectic with diffe rent morphologies is detected.Microstructure transitions from wholly eutectic to primary Al_(2)O_(3)(GAP)dendrite plus eutectic and then to wholly eutectic are found in Al_(2)O_(3)-2 O mol%Gd_(2)O_(3)hypoeutectic(Al_(2)O_(3)-26 mol%Gd_(2)O_(3)hypereutectic)ceramics with the increase of solidification rate.The dendrite growth of faceted Al_(2)O_(3)and non-faceted GAP phases are well predicted by KGT model,which have introduced appro p riate dimensionless supersaturationΩto characterize the anisotropic growth of dendrites.Based on the maximum interface temperature criterion,the competitive growth of primary phase and eutectic is analyzed theoretically and the predicted coupled zone of Al_(2)O_(3)/GAP eutectic ceramics is in good agreement with the experimental results.Besides,the influence of microstructure with these different morphologies on the flexural strength of Al_(2)O_(3)/GAP eutectic ceramics is studied. | Weidan Ma Jun Zhang Haijun Su Guangrao Fan Min Guo Lin Liu Hengzhi Fu | 2021 | Journal of Materials Science & Technology2021，，6： | 3 |
| 9 | Growth,digestive and absorptive capacity and antioxidant status in intestine and hepatopancreas of sub-adult grass carp Ctenopharyngodonidella fed graded levels of dietary threonine显示文摘Background:This study was carried out to investigate effects of threonine levels on growth,digestive and absorptive capacity and antioxidant status in intestine and hepatopancreas of sub-adult grass carp(Ctenopharyngodonidella).Results:Weight gain,specific growth rate,feed intake and feed efficiency were significantly improved by dietary threonine(P<0.05).Intestinal activities of trypsin,chymotrypsin,alpha-amylase,lipase,alkaline phosphatase,y-glutamyl transpeptidase and creatine kinase took the similar trends.Contents of malondialdehyde and protein carbonyl in intestine and hepatopancreas were significantly decreased by dietary optimal threonine supplementation(P<0.05).Anti-superoxide anion capacity,anti-hydroxyl radical capacity,glutathione content and activities of superoxide dismutase,catalase and glutathione-S-transferase in intestine and hepatopancreas were enhanced by dietary threonine(P< 0.05).Conclusions:Dietary threonine could improve growth,enhance digestive and absorptive capacity and antioxidant status in intestine and hepatopancreas of sub-adult grass carp.The dietary threonine requirement of sub-adult grass carp(441.9-1,013.4 g) based on weight gain was 11.6 g/kg diet or 41.5 g/kg of dietary protein by quadratic regression analysis. | Yang Hong Weidan Jiang Shengyao Kuang Kai Hu Ling Tang Yang Liu Jun Jiang Yongan Zhang Xiaoqiu Zhou Lin Feng | 2015 | Journal of Animal Science and Biotechnology2015，6，4： | 3 |
| 10 | Rice Glucose 6-Phosphate/Phosphate Translocator 1 is required for tapetum function and pollen development显示文摘In plants, non-green plastids in heterotrophic tissues are sites for starch and fatty acids biosynthesis,which are essential for plant development and reproduction. Distinct from chloroplasts, the metabolites for these processes in non-green plastids have to be imported through specific transporters. Glucose 6-Phosphate/Phosphate Translocator 1 is required for the uptake of cytosolic Glucose 6-Phosphate into non-green plastids. In Arabidopsis, GPT1 has been demonstrated to play essential roles in male, female gametophyte and embryo development. However, the roles of GPTs in other species are yet largely unknown. Here, we reported that rice OsGPT1 is indispensable for normal tapetal degeneration and pollen exine formation during anther and pollen development. OsGPT1 is localized in the plastid and distributed in the anther wall layers and late-stage pollen grains. Different from the gametic defects caused by mutation in At GPT1, disruption of OsGPT1 does not affect male and female gamete transmission as well as embryo development. On the contrary, osgpt1 mutant exhibits delayed tapetum degeneration,decreased Ubisch bodies formation and thinner pollen exine, leading to pollen abortion at the mature stage. Furthermore, the expression of several genes involved in tapetal programmed cell death(PCD)and sporopollenin formation is decreased in osgpt1. Our study suggests that OsGPT1 coordinates the development of anther sporophytic tissues and the male gametophyte by integrating carbohydrate and fatty acid metabolism in the plastid. | Weidan Zhang Huanjun Li Feiyang Xue Wanqi Liang | 2021 | The Crop Journal2021，9，6： | 2 |
| 11 | Wigner Frequency Point Slice Analysis of Superposition Data for Phased-Array Ground Penetrating Radar显示文摘According to the frequency property of Phased-array ground penetrating radar (PGPR), this paper gives a frequency point slice method based on Wigner time-frequency analysis. This method solves the problem of analysis for the PGPR’s superposition data and makes detecting outcome simpler and detecting target more recognizable. At last, the analytical results of road test data of the Three Gorges prove the analytical method efficient. | ZOULian CHENShu-zhen YANGShen WEIDan XIAOBo-xun | 2004 | Wuhan University Journal of Natural Sciences2004，9，6： | 2 |
| 12 | Dietary isoleucine improved flesh quality,muscle antioxidant capacity,and muscle growth associated with AKT/TOR/S6K1 and AKT/FOXO3a signaling in hybrid bagrid catfish(Pelteobagrus vachelli♀×Leiocassis longirostris♂)显示文摘Background:Muscle is the complex and heterogeneous tissue,which comprises the primary edible part of the trunk of fish and mammals.Previous studies have shown that dietary isoleucine(Ile)exerts beneficial effects on growth in aquatic animals.However,there were limited studies regarding the benefits of Ile on fish muscle and their effects on flesh quality and muscle growth.Thus,this study was conducted to explore whether dietary Ile had affected flesh quality and muscle growth in hybrid bagrid catfish(Pelteobagrus vachelli♀×Leiocassis longirostris♂).Methods:A total of 630 hybrid fish,with an initial average body weight of 33.11±0.09 g,were randomly allotted into seven experimental groups with three replicates each,and respectively fed seven diets with 5.0,7.5,10.0,12.5,15.0,17.5,and 20.0 g Ile/kg diets for 8 weeks.Results:In the present study,we demonstrated that Ile significantly:(1)increased muscle protein and lipid contents and the frequency distribution of myofibers with≤20μm and≥50μm of diameter;(2)improved pH value,shear force,cathepsin B and L activities,hydroxyproline content,resilience,cohesiveness,and decreased cooking loss,lactate content,hardness,springiness,gumminess,and chewiness;(3)decreased reactive oxygen species(ROS),malondialdehyde(MDA),and protein carbonyl(PC)contents,GCLC and Keap1 mRNA levels,and up-regulated CuZnSOD,CAT,GPX1a,GST,and Nrf2 mRNA levels;(4)up-regulated the insulin-like growth factor 1,2(IGF-1,IGF-2),insulin-like growth factor 1 receptor(IGF-1R),proliferating cell nuclear antigen(PCNA),Myf5,Myod,Myog,Mrf4,and MyHC mRNA levels,and decreased MSTN mRNAlevel;(5)increased muscle protein deposition by activating AKT-TOR-S6K1 and AKT-FOXO3a signaling pathways.Conclusion:These results revealed that dietary Ile improved flesh quality,which might be due to increasing nutritional content,physicochemical,texture parameters,and antioxidant ability;promoting muscle growth by affecting myocytes hyperplasia and hypertrophy,and muscle protein deposition associated with protein synthesis and degradation signaling pathways.Finally,the quadratic regression analysis of chewiness,ROS,and protein contents against dietary Ile levels suggested that the optimal dietary Ile levels for hybrid bagrid catfish was estimated to be 14.19,12.36,and 12.78 g/kg diet,corresponding to 36.59,31.87,and 32.96 g/kg dietary protein,respectively. | Qin Jiang Mingyao Yan Ye Zhao Xiaoqiu Zhou Long Yin Lin Feng Yang Liu Weidan Jiang Pei Wu Yan Wang Defang Chen Shiyong Yang Xiaoli Huang Jun Jiang | 2021 | Journal of Animal Science and Biotechnology2021，12，4： | 2 |
| 13 | Lightning spectra in the 850 to 1 400 nm near-infrared region显示文摘 | Weidan C Boye A Crowell L | 1989 | Journal of Geophysical Research-Atmos- pheres1989，，13： | 1 |
| 14 | Lightning spectra in the 850 to 1400 nm near-infrared region显示文摘 | Weidan C A Boy L crowell | 1989 | J Geophys Res1989，94，11： | 1 |
| 15 | Growth rate,body composition, digestive enzymes and transaminase activities,and plasma ammonia concentration of different weight Jian carp(Cyprinus carpio var. Jian)显示文摘The present study investigated the effect of body weight on body composition, digestive and absorptive capacity, transaminase activities in hepatopancreas and muscle, and plasma ammonia concentration of Jian carp(Cyprinus carpio var.Jian). A total of 750 Jian carps(18.0 ± 0.2 g) were randomly distributed into five groups with three replicates and fed the same diet for 56 days. Tissue and plasma samples were collected on days 14, 28,42, and 56. The results were used to develop a mathematical model for specific growth rate, body moisture and fat content, aspartate transaminase activity and alanine aminotransferase activity in hepatopancreas and muscle, plasma ammonia concentration, and trypsin, chymotrypsin, lipase, and amylase activities in hepatopancreas and intestine, activities of creatine kinase, Na^+/K^+-ATPase, alkaline phosphatase, and γ-glutamyl transpeptidase in intestine in Jian carp. There were linear relationships between natural logarithms of above indexes and body weight. The body moisture and fat content, digestive and absorptive enzymes activities, and transaminase activities showed negative allometry against body weight of Jian carp which were partial reasons to explain fish growth rate decreasing. | Jun Jiang Lin Feng Ling Tang Yang Liu Weidan Jiang Xiaoqiu Zhou | 2015 | Animal Nutrition2015，，4： | 1 |
| 16 | Dietary protein levels changed the hardness of muscle by acting on muscle fiber growth and the metabolism of collagen in sub-adult grass carp(Ctenopharyngodon idella)显示文摘Background:Nutrient regulation has been proven to be an effective way to improve the flesh quality in fish.As a necessary nutrient for fish growth,protein accounts for the highest proportion in the fish diet and is expensive.Although our team found that the effect of protein on the muscle hardness of grass carp was probably related to an increased collagen content,the mechanism for this effect has not been deeply explored.Moreover,few studies have explored the protein requirements of sub-adult grass crap(Ctenopharyngodon idella).Therefore,the effects of different dietary protein levels on the growth performance,nutritional value,muscle hardness,muscle fiber growth,collagen metabolism and related molecule expression in grass carp were investigated.Methods:A total of 450 healthy grass carp(721.16±1.98 g)were selected and assigned randomly to six experimen-tal groups with three replicates each(n=25/replicate),and were fed six diets with 15.91%,19.39%,22.10%,25.59%,28.53%and 31.42%protein for 60 d.Results:Appropriate levels of dietary protein increased the feed intake,percentage weight gain,specific growth rate,body composition,unsaturated fatty acid content in muscle,partial free amino acid content in muscle,and muscle hardness of grass carp.These protein levels also increased the muscle fiber density,the frequency of new muscle fibers,the contents of collagen and IGF-1,and the enzyme activities of prolyl 4-hydroxylases and lysyloxidase,and decreased the activity of matrix metalloproteinase-2.At the molecular level,the optimal dietary protein increased col-lagen type Iα1(Colα1),Colα2,PI3K,Akt,S6K1,La ribonucleoprotein domain family member 6a(LARP6a),TGF-β1,Smad2,Smad4,Smad3,tissue inhibitor of metalloproteinase-2,MyoD,Myf5,MyoG and MyHC relative mRNA levels.The levels of the myostatin-1 and myostatin-2 genes were downregulated,and the protein expression levels of p-Smad2,Smad2,Smad4,p-Akt,Akt,LARP6 and Smad3 were increased.Conclusions:The appropriate levels of dietary protein promoted the growth of sub-adult grass carp and improved muscle hardness by promoting the growth of muscle fibers,improving collagen synthesis and depressing collagen degradation.In addition,the dietary protein requirements of sub-adult grass carp were 26.21%and 24.85%according to the quadratic regression analysis of growth performance(SGR)and the muscle hardness(collagen content),respectively. | Min Dong Lu Zhang Pei Wu Lin Feng Weidan Jiang Yang Liu Shengyao Kuang Shuwei Li Haifeng Mi Ling Tang Xiaoqiu Zhou | 2023 | Journal of Animal Science and Biotechnology2023，14，2： | 1 |
| 17 | MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways显示文摘 | Longlong Bao Yan Yan Can Xu Weidan Ji Shuwen Shen Gaoya Xu Yong Zeng Bin Sun Haihua Qian Lei Chen Mengchao Wu Changqing Su Jie Chen | 2013 | Cancer Letters2013，，2： | 1 |
| 18 | NO 2 -sensing properties of porous WO 3 gas sensor based on anodized sputtered tungsten thin film显示文摘 | Jing Zeng Ming Hu Weidan Wang Huiqing Chen Yuxiang Qin | 2011 | Chemical2011，，1： | 1 |
| 19 | One-step electrodeposition synthesis of bisphosphonate loaded magnesium implant:A strategy to modulate drug release for osteoporotic fracture healing显示文摘Osteoporotic fracture with increase of aging population became an urgent orthopedic problem.Bisphosphonates were widely recommended as effective clinical treatment drugs.Combination of biodegradable Mg-based implants and merits of bisphosphonates was suggested for osteoporotic fracture healing.Considering the mild and sustained drug release,a novel one-step electrodeposition synthesis of drug loaded coating was proposed in this study.In comparison to conventional soaking method,encapsulated zoledronate coating by one-step electrodeposition method could modulate drug release in first diffusion-controlled and later degradation-controlled manner.The in vitro cell response to zoledronate loaded coating showed enhanced proliferation and osteogenic differentiation of osteoblasts and no significant inhibition on osteoclasts,which could improve bone-forming and decrease bone resorption due to osteoporosis. | Peng Wan Weidan Wang Lizhen Zheng Ling Qin Ke Yang | 2021 | Journal of Materials Science & Technology2021，，19： | 1 |
| 20 | NO2 -sensing properties of porous WO3 gas sensor based on anodized sputtered tungsten thin film 显示文摘 | Zeng Jing Hu Ming Wang Weidan | 2012 | Sensors and Actuators B2012，161，： | 1 |
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