|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Warming effects on plant biomass allocation and correlations with the soil environment in an alpine meadow,China显示文摘Alpine meadow ecosystem is fragile and highly sensitive to climate change.An understanding of the allocation of above-and below-ground plant biomass and correlations with environmental factors in alpine meadow ecosystem can result in better protection and effective utilization of alpine meadow vegetation.We chose an alpine meadow in the Qinghai-Tibetan Plateau of China as the study area and designed experimental warming plots using a randomized block experimental design.We used single-tube infrared radiators as warming devices,established the warming treatments,and measured plant above- (AGB) and below-ground biomass (BGB) during the growing seasons (May to September) in 2012 and 2013.We determined the allocation of biomass and the relationship between biomass and soil environment under the warming treatment.Biomass indices including above-ground biomass,below-ground biomass and the ratio of root to shoot (R/S) ,and soil factors including soil moisture and soil temperature at different depths were measured.The results showed that (1) BGB of the alpine meadow had the most significant allometric correlation with its AGB (y=298.7x~ (0.44) ,P<0.001) ,but the relationship decreased under warming treatment and the determination coefficient of the functional equation was 0.102 which was less than that of 0.188 of the unwarming treatment (control) ; (2) BGB increased,especially in the deeper soil layers under warming treatment (P>0.05) .At 0–10 cm soil depth,the percentages of BGB under warming treatment were smaller than those of the control treatment with the decreases being 8.52% and 8.23% in 2012 and 2013,respectively.However,the BGB increased 2.13% and 2.06% in 2012 and 2013,respectively,at 10–50 cm soil depths; (3) BGB had significant positive correlations with soil moisture at 100 cm depth and with soil temperature at 20–100 cm depths (P<0.05) ,but the mean correlation coefficient of soil temperature was 0.354,greater than the 0.245 of soil moisture.R/S ratio had a significant negative correlation with soil temperature at 20 cm depth (P<0.05) .The warmer soil temperatures in shallow layers increased the biomass allocation to above-ground plant parts,which leading to the increase in AGB;whereas the enhanced thawing of frozen soil in deep layers causing by warming treatment produced more moisture that affected plant biomass allocation. | XU Manhou LIU Min XUE Xian ZHAI Datong | 2016 | Journal of Arid Land2016，8，5： | 12 |
| 2 | Inactivated Sendai Virus Suppresses Murine Melanoma Growth by Inducing Host Immune Responses and Down-regulating β-catenin Expression显示文摘Objective This paper aims to investigate the anti-tumor mechanism of inactivated Sendai virus (Hemagglutinating virus of Japan envelope, HVJ-E) for murine melanoma (B16F10). Methods The murine dendritic cells (DCs) were treated with HVJ-E, and then the cytokines secreted from DCs and costimulation-related molecules on DCs were measured. Meanwhile, the expression of β-catenin in HVJ-E treated murine melanoma cells was detected. In addition, HVJ-E was intratumorally injected into the melanoma on C57BL/6 mice, and the immune cells, CTL response and tumor volume were analyzed. Results HVJ-E injected into B16F10 melanoma obviously inhibited the growth of the tumor and prolonged the survival time of the tumor-bearing mice. Profiles of cytokines secreted by dendritic cells (DCs) after HVJ-E stimulation showed that the number of cytokines released was significantly higher than that elicited by PBS (P<0.05). The co-stimulation-related molecules on DCs were comparable to those stimulated by LPS. Immunohistochemical examinations demonstrated the repression of β-catenin in B16F10 melanoma cells after HVJ-E treatment. Meanwhile, real-time reverse transcription PCR revealed that HVJ-E induced a remarkable infiltration of CD11c positive cells, chemokine ligand 10 (CXCL10) molecules, interleukin-2 (IL-2) molecule, CD4 + and CD8 + T cells into HVJ-E injected tumors. Furthermore, the mRNA expression level of β-catenin in the HVJ-E injected tumors was also down-regulated. In addition, B16F10-specific CTLs were induced significantly after HVJ-E was injected into the tumor-bearing mice. Conclusion This is the first report to show the effective inhibition of melanoma tumors by HVJ-E alone and the mechanism through which it induces antitumor immune responses and regulates important signal pathways for melanoma invasion. Therefore, HVJ-E shows its prospect as a novel therapeutic for melanoma therapy. | ZHANG Quan YUAN Wei Feng ZHAI Guo Qin XUE Zheng Feng ZHU Hong Fei XU Xiang Ming | 2012 | Biomedical and Environmental Sciences2012，25，5： | 9 |
| 3 | Association between large artery stenosis,cerebral small vessel disease and risk of ischemic stroke显示文摘We aimed to assess the associations of large artery stenosis(LAS)and cerebral small vessel disease(CSVD)with the risk of ischemic stroke and to investigate their respective and combined contributions.In the prospective population-based Shunyi Study,1,082 stroke-free participants aged 55.9±9.1 years were included.Participants were followed for incident stroke throughout the study period(2013-2019).Total small vessel disease score was used to measure CSVD burden.Cervico-cerebral large artery stenosis was evaluated via brain magnetic resonance angiography and carotid ultrasound.We estimated the risk of ischemic stroke in relation to LAS and CSVD with Cox regression models.During a mean follow-up of 4.2 years,34 participants(3.1%)experienced at least one ischemic stroke.Severe LAS(≥50% stenosis versus no stenosis:HR=3.27(95%CI:1.31-8.18))and high CSVD burden(total small vessel disease score 2-4 versus 0 point:HR=12.73(4.83-33.53))were associated with increased stroke risk independently.In multivariate models,CSVD burden(7.72%)explained a larger portion of the variation in stroke risk than severity of LAS(3.49%).Our findings identified that both LAS and CSVD were associated with future ischemic stroke in asymptomatic subjects,while those with high CSVD burden deserve more attention in primary prevention of stroke. | Fei Han Ding-Ding Zhang Fei-Fei Zhai Jun Xue Jiang-Tao Zhang Shuang Yan Li-Xin Zhou Jun Ni Ming Yao Meng Yang Ming-Li Li Zheng-Yu Jin Qing Dai Shu-Yang Zhang Li-Ying Cui Yi-Cheng Zhu | 2021 | Science China(Life Sciences)2021，64，9： | 9 |
| 4 | Molecular evolution of the rice miR395 gene family显示文摘MicroRNAs (miRNAs) are 20-22 nucleotide non-coding RNAs that play important roles in plant and animal development. They are usually processed from larger precursors that can form stem-loop structures. Among 20 miRNA families that are conserved between Arabidopsis and rice, the rice miR395 gene family was unique because it was organized into compact clusters that could be transcribed as one single transcript. We show here that in fact this family had four clusters of total 24 genes. Three of these clusters were segmental duplications. They contained miR395 genes of both 120 bp and 66 bp long. However, only the latter was repeatedly duplicated. The fourth cluster contained miR395 genes of two different sizes that could be the consequences of intergenic recombination of genes from the first three clusters. On each cluster, both 1-duplication and 2-duplication histories were observed based on the sequence similarity between miR395 genes, some of which were nearly identical suggesting a recent origin. This was supported by a miR395 locus survey among several species of the genus Oryza, where two clusters were only found in species with an AA genome, the genome of the cultivated rice. A comparative study of the genomic organization of Medicago truncatula miR395 gene family showed significant expansion of intergenic spaces indicating that the originally clustered genes were drifting away from each other. The diverse genomic organizations of a conserved microRNA gene family in different plant genomes indicated that this important negative gene regulation system has undergone dramatic tune-ups in plant genomes. | Sreelatha GUDDETI De Chun ZHANG Ai Li LI Chuck H. LESEBERG Hui KANG Xiao Guang LI Wen Xue ZHAI Mitrick A. JOHNS Long MAO | 2005 | Cell Research2005，15，8： | 7 |
| 5 | Radical-scavenging activity,ACE-inhibiting capability and identification of rapeseed albumin hydrolysate显示文摘Albumin derived from rapeseed was hydrolyzed sequentially using alcalase and flavorzyme to produce antioxidant peptides.To identify antioxidant peptides,rapeseed albumin hydrolysate(RAH)was fractionated using size exclusion chromatography(G-25).The antioxidant activity and angiotensin I-converting enzyme(ACE)inhibiting activity of rapeseed peptides(RSP)purified from RAH were evaluated.The results revealed that RSP-4 had the highest ABTS radical-scavenging activity(TEAC value=0.24)and ACE-inhibiting capacity(IC50=0.19 mg/mL)compared to other fractions.Moreover,RSP-4 was identified as PFDSYFVC(977 D)by electrospray ionization(ESI)mass spectrometry and tandem mass spectrometry(MS/MS).©2013 Beijing Academy of Food Sciences.Production and hosting by Elsevier B.V.All rights reserved. | Wancong Yu Jie Gao Zhaohui Xue Xiaohong Kou Yifan Wang Lijuan Zhai | 2013 | Food Science and Human Wellness2013，2，2： | 6 |
| 6 | Changes of sphingolipids profiles after ischemia-reperfusion injury in the rat liver显示文摘背景肝的 ischemia-reperfusion (I/R ) 损害发生在许多临床的过程。为肝的 I/R 损害负责的分子的机制然而仍然保持未知。Sphingolipids,特别地 ceramide,在应力和死亡起一个作用导致受体的 hepatocellular 死亡,包括肝 I/R 损害贡献几肝疾病的前进。为了推进,在肝的 I/R 定义 sphingolipids 的角色,在灌注以后的 sphingolipids 的全身的分析是我们调查了的 necessary.Methods 在一只老鼠的 sphingolipids 的 lipidomic 变化温暖的肝的 I/R 损害当模特儿,由推迟的抽取帮助矩阵的激光解吸附作用电离 time-of-flight 团 spectrometry (DE MALDI-TOF-MS ) 。结果 ceramide 和鞘磷脂和 sphingolipids 的大多数类型的紧张的全部的数量,主要鞘磷脂,显著地在灌注以后在 1 个小时增加了(P < 0.05 ) 并且在在灌注以后的 6 个小时的到达山峰(P < 0.01 ) 与控制相比。ceramide 和鞘磷脂的六种新形式出现了在灌注以后的 6 个小时,他们是(m/z ) 537.8, 555.7, 567.7, 583.8, 683.5 和 731.4 分别地。 ceramide-monohexoside ( m/z )( CMH ( d18:1C22:1+Na )^+) 804.4 也在灌注以后增加了并且在 reperfursion.Conclusions 以后与肝损害的程度相关 sphingolipids , ceramide ,鞘磷脂和 ceramide-monohexoside 的三种主要形式,与肝的 I/R 损害有关并且在理解为肝的 I/R 损害负责的机制提供一个新观点。 | ZHAI Shu-ting LIU Guang-yi XUE Fei SUN Gong-ping LIANG Liang CHEN Wei XU Guo-dong LI Jun-jian YANG Jun LIANG Ting-bo | 2009 | Chinese Medical Journal2009，，24： | 5 |
| 7 | The energy performance and passive survivability of high thermal insulation buildings in future climate scenarios显示文摘Given that the passive performance simulation of buildings based on typical meteorological year data and specific design schemes makes it challenging to respond to climate change and refine design requirements on time,this article established a passive performance prediction model for future buildings considering multi-dimensional variables including climate change,building design,and operational characteristics.For high thermal insulation buildings under future climates,the mild climate zone is more sensitive than the others,cooling energy demand is more sensitive than heating demand,apartments are more sensitive than office buildings,and passive survivability is more sensitive than energy performance;for buildings of the same type located in the same climate zone,thermal design solutions determine the increase rate of cooling demand.The potential benefits of climate warming on heating demand reduction are almost zero,but the cooling demand increases significantly,with apartments and office buildings increasing up to 22.1% and 5.0%,respectively.Buildings generally overheat in the future,and the increase rate of the mild zone far exceeds other zones with duration and severity being 3004.8% and 877.7%for apartments,and 884.3% and 288.9%for office buildings,respectively. | Ran Wang Shilei Lu Xue Zhai Wei Feng | 2022 | Building Simulation2022，15，7： | 4 |
| 8 | One-step in situ encapsulation of Ge nanoparticles into porous carbon network with enhanced electron/ion conductivity for lithium storage显示文摘Germanium(Ge) is considered to be one of the most promising anode materials due to the high theoretical capacity and excellent rate capability. However, its further development is hindered by the poor cycling stability caused by the severe volume change. Herein, we demonstrate a one-step in situ synthesis of Ge nanoparticles embedded into porous carbon framework(PC@Ge) using a facile sacrificial template method via the introduction of poly(methyl methacrylate) and subsequent thermal treatment. This unique nanoarchitecture not only enhances lithium-ion diffusivity and electron conductivity, but also effectively buffers the huge volume expansion and protects the Ge nanoparticles from cracking and aggregation during the cycling. Consequently, the as-prepared PC@Ge electrode exhibits superior capacity retention of 75% and 87%over 1000 cycles at 1.0 and 2.0 A·g^(-1), respectively. | Xue Qiao Xue-Biao Yang Na Zhang Xian-Ling Wang Ying-Ying Song Yong-Qing Zhai Dan Li Hong-Qiang Wang | 2021 | Rare Metals2021，40，9： | 4 |
| 9 | Chinese herbal medicine enhances sexual function and c-Fos/nNOS expression in the nucleus accumbens of orchidectomized rats显示文摘OBJECTIVE: To determine whether the central nervous system is involved in the effect of Chinese herbal medicine on sexual function recovery in orchidectomized rats.METHODS: Orchidectomized rats were administered intragastrically with a decoction of 'kidneynourishing' Chinese herbal medicine once per day for 28 days. Accessory genital organ weight, plasma testosterone, and mating behavior were investigated. The expression of c-Fos and neuronal nitric oxide synthase(n NOS) in neuronal cells in the nucleus accumbens(NAc) was analyzed by immunohistochemistry.RESULTS: There was a decrease in accessory genital organ weight, plasma testosterone, and sexual behavior, as well as a low number of c-Fos-positive cells and a large n NOS-positive cell area in orchidectomized rats. Administration of the herbal medicine increased accessory genital organ weight, testosterone level, mating behavior, and c-Fos-positive cell number, while it decreased the n NOS-positive cell area in orchidectomized rats.CONCLUSION: An increase of plasma testosterone after administration of 'kidney-nourishing' herbal medicine might contribute to the elevated sexual function and activity in orchidectomized rats. In addition, a central nervous system mechanism, such as the functional alteration of NAc, might be involved. | Liu Hongyu Cui Jianmei Zhai Haifeng Xue Jinjuan Wang Xiaoyang | 2016 | Journal of Traditional Chinese Medicine2016，36，3： | 4 |
| 10 | Involvement of long non-coding RNAs in the progression of esophageal cancer显示文摘Esophageal cancer(EC)is one of the most common malignant tumors of the digestive system with high incidence and mortality rate worldwide.Therefore,exploring the pathogenesis of ECand searching for new targeted therapies are the current research hotspot for EC treatment.Long non-coding RNAs(lncRNAs)are endogenous RNAs with more than 200 nucleotides,but without proteincoding function.In recent years,lncRNAs have gradually become the focuses in the field of non-coding RNA.Some lncRNAs have been proved to be closely related to the pathogenesis of EC.Many lncRNAs are abnormally expressed in EC and participate in many biological processes including cell proliferation,apoptosis,and metastasis by inhibiting or promoting target gene expression.LncRNAs can also regulate the progression of EC through epithelial-mesenchymal transformation(EMT),which is closely related to the occurrence,development,and prognosis of EC.In this article,we review and discuss the involvement of lncRNAs in the progression of EC. | Wenhua Xue Yuanyuan Zheng Zhibo Shen Lifeng Li Zhirui Fan Wenbin Wang Zijia Zhu Yunkai Zhai Jie Zhao Quancheng Kan | 2021 | Cancer Communications2021，41，5： | 4 |
| 11 | Orthogonal Test Optimization of Extraction Technology of Total Fla-vonoids from Fruits and Leaves of Prunus mume Sieb. et Zucc. and Its in Vitro Anti-oxidation Activity显示文摘[Objectives]To optimize the extraction technology of total flavonoids component,and investigate its in vitro anti-oxidation activity.[Methods]The single factor was inspected firstly. By orthogonal experiment,the best extraction conditions of total flavonoids from fruits and leaves of P. mume Sieb. et Zucc. were determined,and reducing ability of the extracted total flavonoids and its DPPH and ABTS scavenging abilities were explored. [Results] The best extraction technology conditions: solid-liquid ratio of 1∶ 50,ethanol concentration of 50%,extraction time of 2. 5 h,extraction temperature of 85 ℃,two-time extraction. By detecting DPPH and ABTS scavenging abilities of total flavonoids,the anti-oxidation activity of the total flavonoids from fruits and leaves of P. mume Sieb. et Zucc. was analyzed and evaluated. [Conclusions]Fruits and leaves of P. mume Sieb. et Zucc. had a certain in vitro anti-oxidation activity,and heat reflux extraction method of its total flavonoids had high extraction rate and simple and convenient operation,which had some practical value. | Xue ZHAI Qian JIN Haiyan XIANG Fenglin WANG Yuan LIU | 2017 | Medicinal Plant2017，8，2： | 4 |
| 12 | Evaluation of coronary plaque and stent deployment by intravascular optical coherence tomography in elderly patients with unstable angina and non-ST-elevation myocardial infarction显示文摘Objective To evaluate the feasibility and efficacy of intravascular optical coherence tomography (OCT) in the assessment of plaque characteristics and drug eluting stent deployment quality in the elderly patients with unstable angina (UA) and non-ST segment elevation myocardial infarction (NSTEMI). Methods OCT was used in elderly patients undergoing percutaneous coronary interventions. Fifteen patients, 9 males and 6 females with mean age of 72.6±5.3 years (range 67-92 years) were enrolled in the study. Images were obtained before initial balloon dilatation and following stent deployment. The plaque characteristics before dilation, vessel dissection, tissue prolapse, stent apposition and strut distribution after stent implantation were evaluated. Results Fifteen lesions were selected from 32 angiographic lesions as study lesions for OCT imaging after diagnostic coronary angiography. There were 7 lesions in the left anterior descending artery, 5 lesions in the right coronary artery and 3 lesions in the left circumflex coronary artery. Among them, 12 (80.0%) were lipid-rich plaques, and 10 (66.7%) were vulnerable plaques with fibrous cap thickness 54.2±7.3 μm. Seven ruptured culprit plaques (46.7%) were found; 4 in UA patients and 3 in NSTEMI patients. Tissue prolapse was observed in 11 lesions (73.3%). Irregular stent strut distribution was detected in 8 lesions (53.3%). Vessel dissections were found in 5 lesions (33.3%). Incomplete stent apposition was observed in 3 stents (20%) with mean spacing between the struts and the vessel wall 172±96 mm (range 117-436 mm). Conclusions 1) It is safe and feasible to perform intravascular OCT to differentiate vulnerable coronary plaque and monitor stent deployment in elderly patients with UA and USTEMI. 2) Coronary plaques in elderly patients with UA and USTEMI could be divided into acute ruptured plaque, vulnerable plaque, lipid-rich plaque, and stable plaque. 3) Minor or critical plaque rupture is one of the mechanisms of UA in elderly patients. 4) Present drug eluting stent implantation is complicated with multiple tissue prolapses which are associated with irregular strut distributions. 5) The action and significance of tissue prolapse on acute vessel flow and in-stent thrombus and restenosis need to be further studied. | Caiyi LU Shiwen WANG Wei YAN Xingli WU Yuxiao ZHANG Qiao XUE Muyang YAN Peng LIU Rui CHEN Jinyue ZHAI | 2007 | Journal of Geriatric Cardiology2007，4，1： | 3 |
| 13 | National Nutrition and Health Systematic Survey for Children 0–17 Years of Age in China显示文摘The main purpose of the National Nutrition and Health Systematic Survey for children 0-17 years of age in China(CNHSC)was to collect basic data on the nutrition,development,and health status for children in different regions across China using evidence-based,reliable,and cost-effective approaches.Children and their parents or guardians from seven regions(south,southwest,north,northwest,eastern,central,and northeast China)in China were recruited.A multi-stage stratified randomized sampling method was used.Two provinces were randomly sampled from each of the seven regions,from which one urban district and one rural country were also randomly sampled,resulting in a total of 28 survey counties/districts.Dietary surveys,health examinations,laboratory testing,and questionnaires were used to collect dietary intake,nutritional status,child development,and health status information.Nutrition,health,and lifestyle assessment of children and their parents was determined using the Knowledge Attitude Practice(KAP)survey.Greater than 100,000 children(38,000 children<6 years of age and 66,000 children6-17 years of age)completed the survey.The survey provided comprehensive data on child nutrition and health status for future studies and will serve as the basis for an integrated nutrition and health improvement strategies proposal for children in China. | YANG Zhen Yu ZHANG Qian ZHAI Yi XU Tao WANG Yu Ying CHEN Bo Wen TANG Xue Jun YUAN Xiao Lin FANG Hong Yun ZHU Yan PANG Xue Hong WANG Shuo XU Juan LI Rui Li SI Xiang ZHAO Wen Hua | 2021 | Biomedical and Environmental Sciences2021，34，11： | 3 |
| 14 | Whole-body physiology-based pharmacokinetics of caspofungin for general patients, intensive care unit patients and hepatic insufficiency patients显示文摘Caspofungin 是抗真菌的代理人在病人为侵略 candidiasis 作为首要的治疗准许了与的 echinocandin 对到 azoles 的严重的病或最近的暴露中等。在这研究,我们开发了一个整个身体的基于生理学的 pharmacokinetics (WB-PBPK ) 模型预言 caspofungin 的 pharmacokinetics (PK ) ,并且与蒙特卡罗模拟(MCS ) 结合了在病人的不同类型优化 caspofungin 的临床的剂量政体。caspofungin 的一个 WB-PBPK 模型从一般病人,的 4 以前的试用与未加工的数据被造并且验证有孩子呸 B 的特别护理单位(ICU ) 病人,连续肾的代替治疗上的 ICU 病人,温和、中等的肝的 insuffciency (嗨) 病人。MCS 被用来在这些病人优化 caspofungin 的临床的剂量政体。90% 的价值被考虑是为完成最佳的实验治疗的最小的反应(CFR ) 的累积部分。WB-PBPK 模型的模仿的结果在对所有试用的观察价值的好同意。为有 caspofungin 70/50 mg 的将军和 ICU 病人, AUC 和 Cmax 随身体重量(BW ) 的增加被减少并且显示出大变化。MCS 证明所有一般病人不管 BW 完成了 CFR90% 。然而并非有更高的 BW (70 kg ) 的所有 ICU 病人能完成 CFR90% 。与在一般病人的标准剂量政体相比,在有孩子呸 B 的 ICU 病人的 caspofungin 70/35 mg 完成了显著地减少的 AUC 和 Cmax,但是获得了类似的 AUC 和 Cmax 在中等嗨有孩子呸 B 的病人。caspofungin 的 WB-PBPK 模型能正确地预言所有人口的 PK。有 MCS 的联合 WB-PBPK 模型能成功地在所有耐心的人口优化 caspofungin 的临床的剂量政体。 | Qian-ting YANG Ya-jing ZHAI Lu CHEN Tao ZHANG Yan YAN Ti MENG Lei-chao LIU Li-mei CHEN Xue WANG Ya- lin DONG | 2018 | Acta Pharmacologica Sinica2018，39，9： | 3 |
| 15 | Study on Colorimetric Method and Content Determination of Total Phenol in Homemade Plum Wine显示文摘[Objectives] To study on colorimetric method and content determination of total phenol in homemade plum wine. [Methods]The optimal determination condition of total polyphenols content in plum wine( commercially available and homemade) by Folin-Ciocalteu method was inspected,and commercially available and homemade plum wine was evaluated by the method. [Results]The optimal determination conditions of total polyphenols content: sample dose of 1. 0 m L,Folin-Ciocalteu reagent of 1 m L,4% Na_2CO_3 solution of 4. 0 m L,reaction temperature of 50 ℃,reaction time of 1. 5 h,and determination wavelength of 756 nm. Absorbance showed good linear relationship with total polyphenols content within the range of 17. 73-59. 12 μg/m L( y = 14. 878 x + 0. 0739,R^2= 0. 9998). Recovery rate of adding standard sample was between 98. 8% and 103. 5%,and relative standard deviation was 2. 0%( n = 5). [Conclusions]The method had high precision degree and good stability,which was suitable for measuring total polyphenols content in plum wine( commercially available and homemade). | Yun TENG Pei QUN Xue ZHAI Yuan LIU | 2017 | Medicinal Plant2017，8，1： | 2 |
| 16 | Abdominal Obesity and Its Attribution to All-cause Mortality in the General Population with 14 Years Follow-up:Findings from Shanxi Cohort in China显示文摘Objective This study aimed to assess the association of waist circumference(WC)with all-cause mortality among Chinese adults.Methods The baseline data were from Shanxi Province of 2002 China Nutrition and Health Survey.The death investigation and follow-up visit were conducted from December 2015 to March 2016.The visits covered up to 5,360 of 7,007 participants,representing a response rate of 76.5%.The Cox regression model and floating absolute risk were used to estimate hazard ratio and 95%floating CI of death by gender and age groups(≥60 and<60 years old).Sensitivity analysis was performed by excluding current smokers;participants with stroke,hypertension,and diabetes;participants who accidentally died;and participants who died during the first 2 years of follow-up.Results This study followed 67,129 person-years for 12.5 years on average,including 615 deaths.The mortality density was 916 per 100,000 person-years.Low WC was associated with all-cause mortality among men.Multifactor-adjusted hazard ratios(HR)were 1.60(1.35–1.90)for WC<75.0 cm and 1.40(1.11–1.76)for WC ranging from 75.0 cm to 79.9 cm.Low WC(<70.0 cm and 70.0–74.9 cm)and high WC(≥95.0 cm)groups had a high risk of mortality among women.The adjusted HRs of death were 1.43(1.11–1.83),1.39(1.05–1.84),and 1.91(1.13–3.22).Conclusion WC was an important predictor of death independent of body mass index(BMI).WC should be used as a simple rapid screening and predictive indicator of the risk of death. | ZHAI Yi REN Ze Ping ZHANG Mei ZHANG Jian JIANG Yong MI Sheng Quan WANG Zhuo Qun ZHAO Yan Fang SONG Peng Kun YIN Zhao Xue ZHAO Wen Hua | 2020 | Biomedical and Environmental Sciences2020，33，4： | 2 |
| 17 | Dynamic changes and convergence of China's regional green productivity:A dynamic spatial econometric analysis显示文摘Low-carbon economic development is at the heart of the post-pandemic green recovery scheme worldwide.It requires economic recovery without compromising on the environment,implying a critical role that green productivity plays in achieving the carbon neutrality goal.Green productivity measures the quality of economic growth with consideration for energy consumption and environmental pollution.This study employs the slacks-based measure directional distance function(SBM-DDF)approach and the Malmquist-Luenberger(ML)index to calculate green productivity and its components of 30 provinces in China between 2001 and 2018.Using a spatial panel data model,we empirically analyzed the conditionalβ-convergence of China's green productivity.We found that overall,since 2001,China's green productivity has demonstrated a continuous upward trend.When taking into account spatial factors,China's green productivity demonstrates a significant conditionalβ-convergence.In terms of regional effects,the results indicate that the green productivity of the eastern and western regions demonstrates club convergence,implying a more balanced green economic development.Moreover,the convergence rate of China's green productivity increases with the addition of environmental regulation variable,and so the corresponding convergence time decreases.It indicates that environmental regulations help to facilitate the convergence of China's green productivity,narrowing the gap between the regional green economic development.The findings provide guideline for achieving a low-carbon development and carbon neutrality from a regional green productivity perspective. | Xu-Quan ZHAI Rui XUE Bin HE Dong YANG Xiang-Yu PEI Xian LI Yuli SHAN | 2022 | Advances in Climate Change Research2022，13，2： | 2 |
| 18 | Polarized holographic lithography system for high-uniformity microscale patterning with periodic tunability显示文摘Periodic microscale array structures play an important role in diverse applications involving photonic crystals and diffraction gratings.A polarized holographic lithography system is proposed for patterning high-uniformity microscale two-dimensional crossed-grating structures with periodic tunability.Orthogonal two-axis Lloyd’s mirror interference and polarization modulation produce three sub-beams,enabling the formation of two-dimensional crossed-grating patterns with wavelength-comparable periods by a single exposure.The two-dimensional-pattern period can also be flexibly tuned by adjusting the interferometer spatial positioning.Polarization states of three sub-beams,defining the uniformity of the interference fringes,are modulated at their initial-polarization states based on a strict full polarization tracing model in a three-dimensional space.A polarization modulation model is established considering two conditions of eliminating the unexpected interference and providing the desired identical interference intensities.The proposed system is a promising approach for fabricating high-uniformity two-dimensional crossed gratings with a relatively large grating period range of 500–1500 nm.Moreover,our rapid and stable approach for patterning period-tunable two-dimensional-array microstructures with high uniformity could be applicable to other multibeam interference lithography techniques. | Gaopeng Xue Qihang Zhai Haiou Lu Qian Zhou Kai Ni Liyu Lin Xiaohao Wang Xinghui Li | 2021 | Microsystems & Nanoengineering2021，7，2： | 2 |
| 19 | Changing trends of clinicopathologic features and survival duration after surgery for gastric cancer in Northeast China显示文摘BACKGROUND Through analyzing the data from a single institution in Northeast China,this study revealed the possible clinicopathologic characteristics that influence the prognosis of patients with gastric cancer(GC).AIM To evaluate the changing trends of clinicopathologic features and survival duration after surgery in patients with GC in Northeast China,which is a highprevalence area of GC.METHODS The study analyzed the difference in clinicopathologic features and survival duration after surgery of 5887 patients who were histologically diagnosed with GC at the Harbin Medical University Cancer Hospital.The study mainly analyzed the data in three periods,2000 to 2004(Phase 1),2005 to 2009(Phase 2),and 2010 to 2014(Phase 3).RESULTS Over time,the postoperative survival rate significantly increased from 2000 to 2014.In the past 15 years,compared with Phases 1 and 2,the tumor size was smaller in Phase 3(P<0.001),but the proportion of high-medium differentiated tumors increased(P<0.001).The proportion of early GC gradually increased from 3.9%to 14.4%(P<0.001).A surprising improvement was observed in the mean number of retrieved lymph nodes,ranging from 11.4 to 27.5(P<0.001).The overall 5-year survival rate increased from 24%in Phase 1 to 43.8%in Phase 3.Through multivariate analysis,it was found that age,tumor size,histologic type,tumor-node-metastasis stage,depth of invasion,lymph node metastasis,surgical approach,local infiltration,radical extent,number of retrieved lymph nodes,and age group were independent risk factors that influenced the prognosis of patients with GC.CONCLUSION The clinical features of GC in Northeast China changed during the observation period.The increasing detection of early GC and more standardized surgical treatment effectively prolonged lifetimes. | Zhao Zhai Zi-Yu Zhu Xi-Liang Cong Bang-Ling Han Jia-Liang Gao Xin Yin Yu Zhang Sheng-Han Lou Tian-Yi Fang Yi-Min Wang Chun-Feng Li Xue-Feng Yu Yan Ma Ying-Wei Xue | 2020 | World Journal of Gastrointestinal Oncology2020，12，10： | 2 |
| 20 | Photogenerated singlet oxygen over zeolite-confined carbon dots for shape selective catalysis显示文摘Singlet oxygen as an activated oxygen species played an important role in organic synthesis. Suitable catalyst for converting ubiquitous oxygen molecule to singlet oxygen under mild conditions has attracted a wide range of attention. Herein, carbon dots have been confined into mesopores of silicalite-1 nanocrystals framework and acted as active sites for generation of singlet oxygen. The high oxygen-adsorption capacity of zeolite nanocrystals facilitated the photocatalytic generation rate of singlet oxygen, outpacing the free-standing carbon dots for 14-fold. The integrated carbon dot-zeolite nanocrystal hybrid also exhibited a special size-dependent selectivity for organic synthesis by using the in situ formed and confined singlet oxygen as active oxygen species. | Qiu-Ying Yu Guang-Yao Zhai Tian-Lu Cui Hui Su Zhong-Hua Xue Jun-Jun Zhang Peter J.Pauzauskie Shin-ichi Hirano Xin-Hao Li Jie-Sheng Chen | 2019 | Science China Chemistry2019，62，4： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员