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3662篇 您的检索式:作者名="ZHAO L C"
    题名 作者 年代 出处 被引量
1Abnormal activation of the synuclein-gamma gene in hepatocellular carcinomas by epigenetic alteration.显示文摘Zhao W Liu H Liu W Wu Y Chen W Jiang B Zhou Y Xue R Luo C Wang L Jiang JD Liu J 2006中国生物学文摘2006,20,4:31
2体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B 2020中华高血压杂志2020,28,3:22
3Archaeological records of Dadiwan in the past 60 ka and the origin of millet agriculture显示文摘This paper reports the recent excavation of Unit Dadiwan06 at the Dadiwan site in Qin’an County, Gansu.A 65 ka chronological framework is established for Dadiwan06 on the basis of absolute dating (AMS 14C and OSL), stratigraphy, climate change events and archaeology.Artifact distributions reveal patterns of human behavioral variation and adaptation over the past 60 ka, from primitive hunting and gathering to advanced hunting and gathering, to primitive Neolithic agriculture, and finally to advanced Neolithic agriculture.ZHANG DongJu CHEN FaHu BETTINGER R L BARTON L JI DuXue MORGAN C WANG Hui CHENG XiaoZhong DONG GuangHui GUILDERSON T P ZHAO Hui 2010Chinese Science Bulletin2010,55,16:6
4Mutation analysis of autosomal dominant polycystic kidney disease genes in Han Chinese显示文摘Zhang S Mei C Zhang D Dai B Tang B Sun T Zhao H Zhou Y Li L Wu Y Wang W Shen X Song J 2005第二军医大学学报2005,26,8:6
5Establishment and Applications of Epstein-Barr Virus-based Episomal Vectors in Human Embryonic Stem Cells显示文摘Ren C Zhao M Yang X Li D Jiang X Wang L Shan W Yang H Zhou L Zhou W Zhang H 2006中国生物学文摘2006,20,7:4
6高血压对肾小球滤过率降低与脑卒中预后相关性的影响显示文摘该研究旨在比较高血压和非高血压患者估算的肾小球滤过率(estimatedglomerularfiltrationrate,eGFR)较低与脑卒中预后的相关性。方法:获取2012和2013年中国脑卒中登记处确定出院脑卒中患者的资料。低eGFR定义为eGFR%60mL/(min·1.73m2)。应用多因素分析评估低eGFR与1年全因死亡率、复发性脑卒中、功能预后不良(改良的Rankin量表评分3~6分)的关系,分析高血压对相关性的影响。刘莉 叶鹏 Wang X Wang Y Patel UD Xie Barnhart H Li Z Li H Wang C Zhao X Liu L Laskowitz DT 2017中华高血压杂志2017,25,5:4
7阵列型微拓扑结构基底的制备及其对神经细胞电生物物理特性的影响显示文摘以紫外光光刻、硅蚀刻及软光刻技术制备了微柱阵列型细胞培养基底。实验发现,在4μm的结构高度下,当微柱特征尺寸大于或等于4μm时,该法能制备结构规整清晰的聚二甲基硅氧烷微柱阵列型基底。特征尺寸为2μm的基底已经接近该法的极限加工能力,所加工的微柱阵列出现倒伏或缺失。采用一种简单的倾斜角法可以制备一种聚苯乙烯微球致密阵列型基底。该基底的微球直径可以小至2μm或亚微米尺度。细胞培养实验发现,拓扑结构基底能促进神经细胞粘附与铺展,影响细胞静息电位水平,增强电压依从式钙通道功能响应。阵列型拓扑结构基底为构建传感器细胞微环境提供了有效的工程化手段。吴泽志 朱满根 Kisaalita W S Wang L Zhao Y P 林雨 黄岂平 廖彦剑 Li C Z 2011传感技术学报2011,24,4:4
8Identification of human chronic myelogenous leukemia progenitor cells with hemangioblastic characteristics显示文摘Fang B Zheng C Liao L Han Q Sun Z Jiang X Zhao RC 2006中国生物学文摘2006,20,5:3
9Magnetic and transport properties in polycrystalline La2/3Ca1/3MnO3 显示文摘Yuan S L Zhao A Y Xia Z C 2003Solid State Commun2003,125,:2
10Ferroelectric, Piezoelectric and Pyroelectric Properties of Sr1+ xBi4- x- Ti4- xTaxO Ceramics (x=0- 1) 显示文摘Zhao M L Wang C L Zhong W L 2002Jpn J Appl Phys2002,41,:2
11Engrafted bone marrow-derived flk-(1+) mesenchymal stem cells regenerate skin tissue显示文摘Deng W Han Q Liao L Li C Ge W Zhao Z You S Deng H Murad F Zhao RC 2006中国生物学文摘2006,20,5:2
12A photoactive isoprenoid diphosphate analogue containing a stable phosphonate linkage: synthesis and biochemical studies with prenyhransferases 显示文摘DEGRAW A J ZHAO Z STRICKLAND C L 2007J Org Chem2007,72,13:1
13Forward-running detonation drivers for high-enthalpy shock tunnels显示文摘JIANG Z L ZHAO W WANG C 2002AIAA Journal2002,40,10:1
14Thermal evolution of the Archaean basement rocks from the eastern part of the North China Craton and its International Geology Review, bearing on tectonic setting 显示文摘Zhao G C Wilde S A Cawood P A Lu L Z 199840: 706-7211998,40,:1
15Automotive spark-ignited direct-injection gasoline engines显示文摘Zhao F Lai M C Harrington D L 1999Progress in Energy and Combustion Science1999,25,:1
16Alkaline syenites in eastern Cathaysia (South China): Link to Permian-Triassic transtension显示文摘Wang Q Li J W Jian P Zhao Z H Xiong X L Bao Z W Xu J F Li C F Ma J L 2005Emth Planet Sci Lett2005,230,34:1
17Gene transfer agent (GTA) genes reveal diverse and dynamic Roseobacter and Rhodobacter populations in the Chesapeake Bay显示文摘Zhao Y L Wang K Budinoff C 2009Isme Journal2009,3,3:1
18Identification of a conserved linear epitope on the VP1 protein of serotype O foot-and-mouth disease virus by neutralising monoclonal antibody 8E8显示文摘Yang D C Zhang C Y Zhao L 2011Virus Res2011,155,1:1
19Biological properties of the chitosan -gelatin sponge wound dressing 显示文摘DENG C M HE L Z ZHAO M 2007Carbohydr Polym2007,69,3:1
20Expression of bovine trypsin in Lactococcus lactis显示文摘Yao L Man C Zhao F 2010Int Dairy J2010,20,11:1
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