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49篇 您的检索式:作者名="ZHAO Honglin"
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1Strain-based design for buried pipelines subjected to landslides显示文摘Landslides are one of the key problems for stability analysis of pipelines in the western region of China where the geological conditions are extremely complicated. In order to offer a theoretical basis for the pipe-soil interaction, the general finite element program ABAQUS is used to analyze the distribution of pipe strain caused by landslide through which the pipeline passes. In this paper the Ramberg-Osgood constitutive equation is used to study the strain-based mechanical characteristics of pipelines. Different calculation schemas are designed by considering the change of spatial relationship between pipeline and landslide, and the change of D/t, diameter-thickness ratio of pipeline. The results indicate that the pipeline is primarily subjected to tension stress when the landslide crosses the pipeline perpendicularly, the pipe strain is a maximum along the central axis of the landslide, and reverse bending occurs on pipeline at both edges of the landslide. The pipeline is primarily subjected to friction force caused by the downward movement of the landslide, and the friction force is relatively small when the landslide is parallel to the pipeline. The pipe strain is in proportional to D/t, and this means decreasing D/t can help to improve security of pipelines subjected to the landslide.Han Bing Wang Zhiyin Zhao Honglin Jing Hongyuan WuZhangzhong 2012Petroleum Science2012,9,2:22
2Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2显示文摘Emerging and re-emerging RNA viruses occasionally cause epidemics and pandemics worldwide,such as the on-going outbreak of the novel coronavirus SARS-CoV-2.Herein,we identified two potent inhibitors of human DHODH,S312 and S416,with favorable drug-likeness and pharmacokinetic profiles,which all showed broad-spectrum antiviral effects against various RNA viruses,including influenza A virus,Zika virus,Ebola virus,and particularly against SARS-CoV-2.Notably,S416 is reported to be the most potent inhibitor so far with an EC5o of 17 nmol/L and an SI value of 10,505.88 in infec-ted cells.Our results are the first to validate that DHODH is an attractive host target through high antiviral efficacy in vivo and low virus replication in DHODH knock-out cells.This work demonstrates that both S312/S416 and old drugs(Leflunomide/Teriflunomide)with dual actions of antiviral and immuno-regulation may have clinical potentials to cure SARS-CoV-2 or other RNA viruses circulating worldwide,no matter such viruses are mutated or not.Rui Xiong Leike Zhang Shiliang Li Yuan Sun Minyi Ding Yong Wang Yongliang Zhao Yan Wu Weijuan Shang Xiaming Jiang Jiwei Shan Zihao Shen Yi Tong Liuxin Xu Yu Chen Yingle Liu Gang Zou Dimitri Lavillete Zhenjiang Zhao Rui Wang Lili Zhu Gengfu Xiao Ke Lan Honglin Li Ke Xu 2020Protein & Cell2020,11,10:14
3Metal Sealing Performance of Subsea X-tree Wellhead Connector Sealer显示文摘The metal sealing performance of subsea X-tree wellhead connectors is crucial for the safety and reliability of subsea X-trees. In order to establish the theoretical relation between metal sealing ring's contact stress and its structural parameters and working pressure, a mechanical analysis method for double-cone sealing of high pressure vessels is applied in analyzing the metal sealing ring under the condition of preload and operation. As a result, the formula of the unit sealing load for the metal sealing ring under operation with residual preload is shown in this paper, which ensures that the metal sealing ring has an excellent sealing effect and can prevent the metal sealing ring from yielding. Besides, while analyzing the sealing process of the metal sealing ring, the change rule of contact stress and working pressure is concluded here, putting forward that the structural parameters of the metal sealing ring are the major factors affecting the change rule. Finally, the analytical solution through theoretical analysis is compared with the simulation result through finite element analysis in a force feedback experiment, and both are consistent with each other, which fully verifies for the design and calculation theory on metal sealing ring's contact stress and its structural parameters and working pressure deduced in this paper. The proposed research will be treated as an applicable theory guiding the design of metal seal for subsea X-tree wellhead connectors.ZHAO Honglin CHEN Rui LUO Xiaolan DUAN Menglan LU Yinghui FU Guowei TIAN Hongping YE Daohui 2015Chinese Journal of Mechanical Engineering2015,28,3:9
4Construction of an integrated map and location of a bruchid resistance gene in mung bean显示文摘Bruchid beetle(Callosobruchus chinensis) poses a serious threat to the production and storage of mung bean(Vigna radiata). Mapping bruchid resistance(Br) will provide an important basis for cloning the responsible gene(s) and elucidating its functional mechanism, and will also facilitate marker-assisted selection in mung bean breeding. Here, we report the construction of the genetic linkage groups of mung bean and mapping of the Br1 locus using an RIL population derived from a cross between Berken, a bruchid-susceptible line, and ACC41, a bruchid-resistant line. A total of 560 markers were mapped onto 11 linkage groups,with 38.0% of the markers showing distorted segregation. The lengths of the linkage groups ranged from 45.2 to 117.0 c M with a total coverage of 732.9 c M and an average interval of1.3 c M between loci. Br1 was located on LG9 between BM202(0.7 c M) and Vr2-627(1.7 c M).Based on 270 shared SSR markers, most of the linkage groups were assigned to specific chromosomes. These results should further accelerate the genetic study of this crop.Lixia Wang Chuanshu Wu Min Zhong Dan Zhao Li Mei Honglin Chen Suhua Wang Chunji Liu Xuzhen Cheng 2016The Crop Journal2016,4,5:9
5Recent Progress in Distributed Optical Fiber Raman Photon Sensors at China Jiliang University显示文摘在在中国 Jiliang 大学(CJLU ) 的完整的分布式的纤维拉曼光子传感器的研究,生产和应用的最近的进步的简短评论被介绍。以便改进测量距离,精确性,空间分辨率,多参数大小的能力,和完整的分布式的纤维传感器系统的智力,一种新一代纤维传感器技术基于光纤维,非线性的散布熔化原则被建议。一系列新一代完整的分布式的纤维传感器被调查并且设计,它由新产生组成极端长的距离散布与一个纤维拉曼放大器综合的光子传感器的完整的分布式的纤维拉曼和瑞利,汽车修正完整的分布式的纤维拉曼光子温度传感器基于拉曼关联双来源,完整的分布式的纤维拉曼光子温度传感器基于编码的脉搏采购原料,完整的分布式的纤维拉曼光子温度传感器Zaixuan ZHANG 2012Photonic Sensors2012,2,2:8
6Automatic detection of oceanic eddies in reanalyzed SST images and its application in the East China Sea显示文摘Oceanic eddies may cause local sea surface temperature(SST), height, and salinity anomalies in remote sensing(RS) images. Remote sensed SST imagery has proven to be an effective technique in oceanic eddy detection, because of its high temporal and spatial resolution. Various techniques have been used to identify eddies from SST images. However, mainly owing to the strong morphological variation of oceanic eddies, there is arguably no uniquely correct eddy detection method. A scheme of algorithm based on quasi-contour tracing and clustering of eddy detection from SST dataset is presented. The method does not impose fixed restrictions or limitations during the course of 'suspected' eddy detection, and any eddy-like structures can be detected as 'suspected' eddies. Then, 'true' eddies can be identified based on the combination of intensity and spatial/temporal scale criteria. This approach has been applied to detect eddies in the East China Sea by using Operational SST & Sea Ice Analysis(OSTIA) dataset. Experiments proved that oceanic eddies ranging in diameter from tens to hundreds of kilometers can be detected. Through investigation of the 2007–2011 OSTIA daily SST dataset from the Kuroshio region in the East China Sea, we found that the most active regions for oceanic eddies are those along the Kuroshio path, northeast of Taiwan Island, the Yangtze Estuary and the Ryukyu Islands. About 86% of the cyclonic eddies and 87% of the anticyclonic eddies have the size of 50–100 km in diameter. Only 25% of the anticyclonic eddy and 26% of the cyclonic eddy have the strength more than 0.4°C in the sea surface layer.ZHANG ChunHua LI HongLin LIU SongTao SHAO LianJun ZHAO Zhao LIU HongWei 2015Science China Earth Sciences2015,58,12:8
7A Small-Scale Medication of Leflunomide as a Treatment of COVID-19 in an Open-Label Blank-Controlled Clinical Trial显示文摘We recently reported that inhibitors against human dihydroorotate dehydrogenase(DHODH)have broad-spectrum antiviral activities including their inhibitory efficacies on SARS-CoV-2 replication in infected cells.However,there are limited data from clinical studies to prove the application of DHODH inhibitors in Coronavirus disease 2019(COVID-19)patients.In the present study,we evaluated Leflunomide,an approved DHODH inhibitor widely used as a modest immune regulator to treat autoimmune diseases,in treating COVID-19 disease with a small-scale of patients.Cases of 10 laboratory-confirmed COVID-19 patients of moderate type with obvious opacity in the lung were included.Five of the patients were treated with Leflunomide,and another five were treated as blank controls without a placebo.All the patients accepted standard supportive treatment for COVID-19.The patients given Leflunomide had a shorter viral shedding time(median of5 days)than the controls(median of 11 days,P=0.046).The patients given Leflunomide also showed a significant reduction in C-reactive protein levels,indicating that immunopathological inflammation was well controlled.No obvious adverse effects were observed in Leflunomide-treated patients,and they all discharged from the hospital faster than controls.This preliminary study on a small-scale compassionate use of Leflunomide provides clues for further understanding of Leflunomide as a potential antiviral drug against COVID-19.Ke Hu Mengmei Wang Yang Zhao Yunting Zhang Tao Wang Zhishui Zheng Xiaochen Li Shaolin Zeng Dong Zhao Honglin Li Ke Xu Ke Lan 2020Virologica Sinica2020,35,6:7
8Determination of trace and rare-earth elements in Chinese soil and clay reference materials by ICP-MS显示文摘Inductively coupled plasma mass spectrometry(ICP-MS) has become a powerful tool for providing reliable analytical results in many laboratories around the word. In this study, the mixture of HF and HNO3 acids in high-temperature and high-pressure closed-vessel digestion technique were used to decompose some Chinese reference materials, and thirty seven elements were determined by ICP-MS. Most of the results for Chinese soil reference materials were found to be in reasonable agreement with the reference values, except Cs, Ta, Li, Ge, Zn, Nd, Tb and Ta whose values need to be revised. Their precisions were typically lower than 5% RSD. However, the Precisions of Chinese clay reference materials, especially for GBW03102 and GBW03102a, were significantly different with reference values, probably reflecting the existence of a coarser-grained fraction(>70 μm) in samples, and the formation of fluorides in Al-rich samples during sample decomposition by using the mixture of HF and HNO3 acids. Moreover, thirty-seven trace elements covering the mass range from Li to U in four Chinese clay reference materials were firstly provided with good precision and accuracy in this study.LIU Ye DIWU Chunrong ZHAO Yan LIU Xiaoming YUAN Honglin WANG Jianqi 2014Chinese Journal Of Geochemistry2014,33,1:6
9“Exploring petroleum inside source kitchen”: Shale oil and gas in Sichuan Basin显示文摘The Sichuan Basin is rich in shale oil and gas resources,with favorable geological conditions that the other shale reservoirs in China cannot match.Thus,the basin is an ideal option for fully'exploring petroleum inside source kitchen'with respect to onshore shale oil and gas in China.This paper analyzes the characteristics of shale oil and gas resources in the United States and China,and points out that maturity plays an important role in controlling shale oil and gas composition.US shale oil and gas exhibit high proportions of light hydrocarbon and wet gas,whereas Chinese marine and transitional shale gas is mainly dry gas and continental shale oil is generally heavy.A comprehensive geological study of shale oil and gas in the Sichuan Basin reveals findings with respect to the following three aspects.First,there are multiple sets of organic-rich shale reservoirs of three types in the basin,such as the Cambrian Qiongzhusi Formation and Ordovician Wufeng Formation-Silurian Longmaxi Formation marine shale,Permian Longtan Formation transitional shale,Triassic Xujiahe Formation lake-swamp shale,and Jurassic lacustrine shale.Marine shale gas enrichment is mainly controlled by four elements:Deep-water shelf facies,moderate thermal evolution,calcium-rich and silicon-rich rock association,and closed roof/floor.Second,the'sweet section'is generally characterized by high total organic carbon,high gas content,large porosity,high brittle minerals content,high formation pressure,and the presence of lamellation/bedding and natural microfractures.Moreover,the'sweet area'is generally characterized by very thick organic-rich shale,moderate thermal evolution,good preservation conditions,and shallow burial depth,which are exemplified by the shale oil and gas in the Wufeng-Longmaxi Formation,Longtan Formation,and Daanzhai Member of the Ziliujing Formation.Third,the marine,transitional,and continental shale oil and gas resources in the Sichuan Basin account for 50%,25%,and 30%of the respective types of shale oil and gas geological resources in China,with great potential to become the cradle of the shale oil and gas industrial revolution in China.Following the'Conventional Daqing-Oil'(i.e.,the Daqing oilfield in the Songliao Basin)and the'Western Daqing-Oil&Gas'(i.e.,the Changqing oilfield in the Ordos Basin),the Southwest oil and gas field in the Sichuan Basin is expected to be built into a'Sichuan-Chongqing Daqing-Gas'in China.Caineng ZOU Zhi YANG Shasha SUN Qun ZHAO Wenhua BAI Honglin LIU Songqi PAN Songtao WU Yilin YUAN 2020Science China Earth Sciences2020,63,7:6
10Effects of freeze–thaw cycles on soil N_2O concentration and flux in the permafrost regions of the Qinghai–Tibetan Plateau显示文摘Nitrous oxide(N_2 O) is one of the most important greenhouse gases in the atmosphere; freeze–thaw cycles(FTCs) might strongly influence the emission of soil N_2 O on the Qinghai–Tibetan Plateau(QTP). However, there is a lack of in situ research on the characteristics of soil N_2 O concentration and flux in response to variations in soil properties caused by FTCs.Here, we report the effect of FTC-induced changes in soil properties on the soil N_2 O concentration and flux in the permafrost region of the higher reaches of the Shule River Basin on the northeastern margin of the QTP. We measured chemical properties of the topsoil, activities of soil microorganisms, and air temperature(AT), as well as soil N_2 O concentration and flux, over an annual cycle from July 31, 2011, to July 30, 2012. The results showed that soil N_2 O concentration was significantly affected by soil temperature(ST), soil moisture(SM), soil salinity(SS), soil polyphenol oxidase(SPO), soil alkaline phosphatase(SAP), and soil culturable actinomycetes(SCA), ranked as SM>SS>ST>SPO>SAP>SCA, whereas ST significantly increased soil N_2 O flux, compared with SS. Overall, our study indicated that the soil N_2 O concentration and flux in permafrost zone FTCs were strongly affected by soil properties, especially soil moisture, soil salinity, and soil temperature.ShengYun Chen Qian Zhao WenJie Liu Zhao Zhang Shuo Li HongLin Li ZhongNan Nie LingXi Zhou ShiChang Kang 2018Research in Cold and Arid Regions2018,10,1:4
11Uptake, translocation, and debromination of polybrominated diphenyl ethers in maize显示文摘Uptake, translocation and debromination of three polybrominated diphenyl ethers (PBDEs), BDE-28, -47 and -99, in maize were studied in a hydroponic experiment. Roots took up most of the PBDEs in the culture solutions and more highly brominated PBDEs had a stronger uptake capability. PBDEs were detected in the stems and leaves of maize after exposure but rarely detected in the blank control plants. Furthermore, PBDE concentrations decreased from roots to stems and then to leaves, and a very clear decreasing gradient was found in segments upwards along the stem. These altogether provide substantiating evidence for the acropetal translocation of PBDEs in maize. More highly brominated PBDEs were translocated with more difficulty. Radial translocation of PBDEs from nodes to sheath inside maize was also observed. Both acropetal and radial translocations were enhanced at higher transpiration rates, suggesting that PBDE transport was probably driven by the transpiration stream. Debromination of PBDEs occurred in all parts of the maize, and debromination patterns of different parent PBDEs and in different parts of a plant were similar but with some differences. This study for the first time provides direct evidence for the acropetal translocation of PBDEs within plants, elucidates the process of PBDE transport and clarifies the debromination products of PBDEs in maize.Moming Zhao Shuzhen Zhang Sen Wang Honglin Huang 2012Journal of Environmental Sciences2012,24,3:3
12Delay-Based Cross-Layer QoS Scheme for Video Streaming in Wireless Ad Hoc Networks显示文摘With correlating with human perception, quality of experience(Qo E) is also an important measurement in evaluation of video quality in addition to quality of service(Qo S). A cross-layer scheme based on Lyapunov optimization framework for H.264/AVC video streaming over wireless Ad hoc networks is proposed, with increasing both Qo E and Qo S performances. Different from existing works, this scheme routes and schedules video packets according to the statuses of the frame buffers at the destination nodes to reduce buffer underflows and to increase video playout continuity. The waiting time of head-ofline packets of data queues are considered in routing and scheduling to reduce the average end-to-end delay of video sessions. Different types of packets are allocated with different priorities according to their generated rates under H.264/AVC. To reduce the computational complexity, a distributed media access control policy and a power control algorithm cooperating with the media access policy are proposed. Simulation results show that, compared with existing schemes, this scheme can improve both the Qo S and Qo E performances. The average peak signal-to-noise ratio(PSNR) of the received video streams is also increased.Shu Fan Honglin Zhao 2018China Communications2018,15,9:2
13Snow and ice thicknesses derived from Fast Ice Prediction System Version 2.0(FIPS V2.0)in Prydz Bay,East Antarctica:comparison with in-situ observations显示文摘In this paper,snow and ice thickness products derived from an updated Fast Ice Prediction System Version 2.0(FIPS V2.0)in Prydz Bay,East Antarctica,are introduced and compared with in-situ obser-vations.FIPS V2.0 is comprised of a newly-developed snowdrift parameterization compared to the original FIPS V1.0.The simulation domain covers the entire fast ice region in Prydz Bay and is config-ured to 720 grid cells,with a spatial resolution of 0.125°.The ERAInterim reanalysis from the European Centre for Medium-Range Weather Forecasting(ECMWF)were used as the atmospheric forcing.The in-situ observations were obtained near Zhongshan Station by the wintering team,and the measurement frequency of the snow and ice thicknesses was around one week.Both the FIPS V2.0 pro-ducts and in-situ observations introduced in this paper cover the time periods from 2012 to 2016.The primary assessments based on the in-situ observations show that FIPS V2.0 has mean biases of 0.01±0.07 m and 0.23±0.09 m for snow and ice thickness simula-tions,respectively.The results indicate that the updated FIPS V2.0 produces a reasonable snow thickness due to the newly-developed snowdrift parameterization,but it overestimates the ice thickness due to the cold bias in the air temperature forcing.These 2-D snow and ice thickness distributions provide important references for sea ice thermodynamic studies,remote sensing validations,and ice-breaker navigation assessments in this region.The dataset is avail-able at http://gffzza4c772bdab62464fho0wx5pucqbfp6bcq.ffgz.tsg.suse.edu.cn/10.11922/sciencedb.j00076.00066.Jiechen Zhao Jingjing Cheng Zhongxiang Tian Xiaopeng Han Hui Shen Guanghua Hao Honglin Guo Qi Shu 2022Big Earth Data2022,6,4:2
14China's industrial competitiveness in the World 显示文摘Zhao Zhongxiu Zhang Kevin Honglin 2007The Chinese Economy2007,40,6:1
15Design of hydraulic system of subsea X-tree 显示文摘Zhao Honglin Yu Jia Yue Yuanlong 2012Applied Mechanics and Materials2012,,155156:1
16Cooperative wireless networks for better green services显示文摘In order to guarantee the overall return on investment (ROI), improve user experience and quality of service (QoS), save energy, reduce electra magnetic interference (EMI) and radiation pollution, and enable the sustainable deployment of new profitable applications and services in heterogeneous wireless networks coexistence reality, this paper proposes a cross-network cooperation mechanism to effectively share network resources and infrastructures, and then adaptively control and match multi-network energy distribution characteristics according to actual user/service requirements in different geographic areas. Some idle or lightly-loaded base stations (BS or BSs) will be temporally turned off for saving energy and reducing EMI. Initial simulation results show that the proposed approach can significantly improve the overall energy efficiency and QoS performance across multiple cooperative wireless networks.Yang Yang Zhang Wuxiong Hu Honglin Zhang Sihai Wang Xin Zhao Haitao Zhou Wuyang Wei Jibo 2011Engineering Sciences2011,9,1:1
17Highly efficient metal-free catalyst from cellulose for hydrogen peroxide photoproduction instructed by machine learning and transient photovoltage technology显示文摘Great attention has been paid to green procedures and technologies for the design of environmental catalytic systems.Biomassderived catalysts represent one of the greener alternatives for green catalysis.Photocatalytic production of hydrogen peroxide(H_(2)O_(2))from O_(2) and H_(2)O is an ideal green way and has attracted widespread attention.Here,we show a metal-free photocatalyst from cellulose,which has a high photocatalytic activity for the photoproduction of H_(2)O_(2) with the reaction rate up to 2,093μmol/(h·g)and the apparent quantum efficiency of 2.33%.Importantly,a machine learning model was constructed to guide the synthesis of this metal-free photocatalyst.With the help of transient photovoltage(TPV)tests,we optimized their fabrication and catalytic activity,and clearly showed that the formation of carbon dots(CDs)facilitates the generation,separation,and transfer of photo-induced charges on the catalyst surface.This work provides a green way for the highly efficient metal-free photocatalyst design and study from biomass materials with the machine learning and TPV technology.Yan Liu Xiao Wang Yajie Zhao Qingyao Wu Haodong Nie Honglin Si Hui Huang Yang Liu Mingwang Shao Zhenhui Kang 2022Nano Research2022,15,5:1
18Hybrid orthogonal and non-orthogonal pilot distribution based channel estimation in massive MIMO system显示文摘How to obtain accurate channel state information(CSI)at the transmitter with less pilot overhead for frequency division duplexing(FDD) massive multiple-input multiple-output(MIMO)system is a challenging issue due to the large number of antennas. To reduce the overwhelming pilot overhead, a hybrid orthogonal and non-orthogonal pilot distribution at the base station(BS),which is a generalization of the existing pilot distribution scheme,is proposed by exploiting the common sparsity of channel due to the compact antenna arrangement. Then the block sparsity for antennas with hybrid pilot distribution is derived respectively and can be used to obtain channel impulse response. By employing the theoretical analysis of block sparse recovery, the total coherence criterion is proposed to optimize the sensing matrix composed by orthogonal pilots. Due to the huge complexity of optimal pilot acquisition, a genetic algorithm based pilot allocation(GAPA) algorithm is proposed to acquire optimal pilot distribution locations with fast convergence. Furthermore, the Cramer Rao lower bound is derived for non-orthogonal pilot-based channel estimation and can be asymptotically approached by the prior support set, especially when the optimized pilot is employed.ZHANG Ruoyu ZHAO Honglin ZHANG Jiayan JIA Shaobo 2018Journal of Systems Engineering and Electronics2018,29,5:1
19Triazole and Benzotriazole Derivatives as Novel Inhibitors for p90 Ribosomal S6 Protein Kinase 2: Synthesis, Molecular Docking and SAR Analysis显示文摘是的一系列 triazole 和 benzotriazole 衍生物新奇 p90 ribosomal S6 蛋白质 kinase 2 (RSK2 ) 禁止者被设计并且综合。在里面对 RSK2 的 vitro 活动被评估,并且在 14 之中加重 5, 6, 11, 12, 13 和 14 展出的酶 IC50 8.91, 2.86, 3.19, 3.05, 4.49 和 2.09 楴敶愠瑣癩瑩敩 ? 湩猠浯 ? 畴潭 ?Jun Yuan Ye Zhong Shiliang Li Xue Zhao Guoqin Luan Zhenjiang Zhao Jin Huang Honglin Li Yufang Xu 2013Chinese Journal of Chemistry2013,31,9:1
20Performance Analysis of Physical Layer Security over α-η-κ-μ Fading Channels显示文摘In this paper, we consider the secure data transmission over α-η-κ-μ fading channels, which are recently proposed to encompass nearly all the well-known statistical models adopted in the literature. In particular, we address the secrecy performance in terms of the average secrecy capacity(ASC) and the secrecy outage probability(SOP), for which novel analytical expressions are derived. Simulation results verify the analysis and demonstrate the impact of the physical parameters on the secrecy performance of this new channel fading model.Shaobo Jia Jiayan Zhang Honglin Zhao Yao Xu 2018China Communications2018,15,11:1
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