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247篇 您的检索式:作者名="Zhan Dong"
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1The prognostic value of preoperative serum levels of CEA,CA19-9 and CA72-4 in patients with colorectal cancer显示文摘INTRODUCTIONCarcinoembryonic antigen ( CEA) , originally described by Gold and Freedman [1] in 1965, is now an acknowledged member of immunoglobulin superfamily[2],with a role as an intracellular adhesion molecule[3].Carbohydrate antigen 19-9(CA19-9), obtained with a monoclonal antibody produced by immunizing a monoclonal antibody produced by immunizing a mouse with a colonic cancer cell line in 1979[4],is a ligand for E-selectin that plays an important role in the addhesion of cancer cells to endothelial cells [5,6].Chao Xu Zheng~1 Wen Hua Zhan~1 Ji Zong Zhao~2 Dong Zheng~3 Dong Ping Wang~1 Yu Long He~1 Zhang Qing Zheng~1 ~1Department of General Surgery,~2Laboratory of Surgery,~3Department of Medicine,First Affiliated Hospital,Sun Yat-Sen University of Medical Sciences,Guangzhou 510080,Guangdong Province,ChinaDr.Chao Xu Zheng now working as a surgeon and lecturer in the Department of General Surgery,First Affiliated Hospital,Sun Yat-Sen University of Medical Sciences,who is a Ph.D.student,having 7 papers published. 2001World Journal of Gastroenterology2001,7,3:25
2Serum uric acid levels correlate with recurrence of paroxysmal atrial fibrillation after catheter ablation显示文摘HE Xiao-nan LI Song-nan ZHAN Jin-liang XIE Shuang-lun ZHANG Zhi-jun DONG Jian-zeng YU Rong-hui LONG De-yong TANG Ri-bo MA Chang-sheng 2013Chinese Medical Journal2013,,5:18
3Exploring an Integrative Therapy for Treating COVID-19:A Randomized Controlled Trial显示文摘Objectives:To develop a new Chinese medicine(CM)-based drug and to evaluate its safety and effect for suppressing acute respiratory distress syndrome(ARDS)in COVID-19 patients.Methods:A putative ARDS-suppressing drug Keguan-1 was first developed and then evaluated by a randomized,controlled two-arm trial.The two arms of the trial consist of a control therapy(alpha interferon inhalation,50(x g twice daily;and lopinavir/ritonavir,400 and 100 mg twice daily,respectively)and a testing therapy(control therapy plus Keguan-119.4 g twice daily)by random number table at 1:1 ratio with 24 cases each group.After 2-week treatment,adverse events,time to fever resolution,ARDS development,and lung injury on newly diagnosed COVID-19 patients were assessed.Results:An analysis of the data from the first 30 participants showed that the control arm and the testing arm did not exhibit any significant differences in terms of adverse events.Based on this result,the study was expanded to include a total of 48 participants(24 cases each arm).The results show that compared with the control arm,the testing arm exhibited a significant improvement in time to fever resolution(P=0.035),and a significant reduction in the development of ARDS(P=0.048).Conclusions:Keguan-1-based integrative therapy was safe and superior to the standard therapy in suppressing the development of ARDS in COVID-19 patients.(Trial registration No.NCT 04251871 at www.clinicaltrials.gov).WANG Jia-bo WANG Zhong-xia JING Jing ZHAO Peng DONG Jing-hui ZHOU Yong-feng YANG Guang NIU Ming ZHAO Xu JIANG Tian-jun Bl Jing-feng XU Zhe ZHANG Ping WU Dan BAI Zhao-fang GUO Yu-ming YU Si-miao SUN Yong-qiang ZHANG Zi-teng ZHAN Xiao-yan LI Peng-yan DING Jin-biao ZHAO Peng-fei SONG Xue-ai TANG Jian-yuan HE Dong-chu CHEN Zhu QIN En-qiang WANG Rui-lin XIAO Xiao-he 2020Chinese Journal of Integrative Medicine2020,26,9:18
4The ceramide pathway is involved in the survival, apoptosis and exosome functions of human multiple myeloma cells in vitro显示文摘多重骨髓瘤(公里) 被恶意的血浆房间和倔强的同种细胞的增长描绘到传统的治疗。exosomes 涉及 modulating,这被显示出前进和通过 microRNAs (米尔) 的癌症的转移。Ceramide 是 sphingolipid 的一种类型;exosomal 分泌物的 ceramide 小径被显示了影响癌症房间的 apoptosis。但是在公里房间功能, exosome 功能和米尔规定的这条小径的角色仍然保持未知。在这研究,我们显示出那 C6 ceramide (外长的 ceramide 补充, 1.25-40 mol/L ) dose-dependently 禁止了增长并且在人的公里 OPM2 房间线支持了 apoptosis,它与提高的 caspase 3/9 和 PARP 劈开被联系。我们也发现 C6 ceramide (5-20 mol/L ) dose-dependently 刺激了 exosome 分泌物并且增加了肿瘤镇压的米尔的 exosomal 层次(米尔 202,米尔 16,米尔 29b 和米尔 15a ) 。笔记,从 C6 对待 ceramide 的 OPM2 房间的 exosomes 能影响接受者 OPM2 房间的增长和 apoptosis,它与增加的肿瘤镇压的 exosomal 米尔相关。相反, GW4869 (一个 ceramide 禁止者, 5-20 mol/L ) 在公里 exosomes 在公里功能, exosome 分泌物和米尔层次的规定上施加了相反的效果。然而,从对待 GW4869 的 OPM2 房间的 exosomes 没在这些米尔和指向的 OPM2 房间的幸存上有效果。一起拿,我们的调查结果表明 ceramide 小径调制公里幸存,可能直接经由 caspase 小径并且间接地经由 exosomal 米尔机制。Qian CHENG Xin LI Yue WANG Min DONG Feng-huang ZHAN Jing LIU 2018Acta Pharmacologica Sinica2018,39,4:15
5Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis显示文摘Complement is known to play a role in alcoholic fatty liver disease (AFLD), but the underlying mechanisms are poorly understood, thereby constraining the development of a rational approach for therapeutic intervention in the complement system. C3 deficiency has been shown to impart protective effects against ethanol-induced hepatic steatosis and inflammation. Here we demonstrate a protection effect in wild-type mice by treatment with CR2-Crry, a specific inhibitor of C3 activation. The expression of glycine transfer (t) RNA-derived fragments (Gly-tRFs) is upregulated in ethanol-fed mice and inhibition of Gly-tRFs in vivo decreases chronic ethanol feeding-induced hepatosteatosis without affecting inflammation. The expression of Gly-tRF was downregulated in C3-deficient or CR2-Crry-treated mice, but not in C5-deficient mice;Gly-tRF expression was restored by the C3 activation products C3a or Asp (C3a-des-Arg) via the regulation of CYP2E1. Transcriptome profiling of hepatic tissues showed that Gly-tRF inhibitors upregulate the expression of sirtuin1 (Sirt1) and subsequently affect downstream lipogenesis and β-oxidation pathways. Mechanistically, Gly-tRF interacts with AGO3 to downregulate Sirt1 expression via sequence complementarity in the 3′ UTR. Notably, the expression levels of C3d, CYP2E1 and Gly-tRF are upregulated, whereas Sirt1 is decreased in AFLD patients compared to healthy controls. Collectively, our findings suggest that C3 activation products contribute to hepatosteatosis by regulating the expression of Gly-tRF. Complement inhibition at the C3 activation step and treatment with Gly-tRF inhibitors may be potential and precise therapeutic approaches for AFLD.Fudi Zhong Zhigao Hu Keqing Jiang Biao Lei Zhan Wu Guandou Yuan Hongliang Luo Chunqiang Dong Bo Tang Chaowen Zheng Shuai Yang Yonglian Zeng Zhenya Guo Shuiping Yu Huizhao Su Guo Zhang Xiaoqiang Qiu Stephen Tomlinson Songqing He 2019Cell Research2019,29,7:14
6Gene-Gene Interaction of GJB2, SOD2, and CAT on Occupational Noise-induced Hearing Loss in Chinese Han Population显示文摘The effects of genetic factors on the noise-induced hearing loss(NIHL)are still unclear.In the present study,eight single-nucleotide polymorphisms(SNPs)included rs1227049 and rs3802711(CDH23),rs1695(GSTP1),rs137852540(GJB2),rs2289274(PMCA2),rs4880(SOD2),rs7943316,and rs769214 within CAT that might associated with NIHL were further validatedWANG Sheng Li YU Lu Gang LIU Ren Ping ZHU Wan Zhan GAO Wei Min XUE Li Ping JIANG Xu ZHANG Ya Han YI Ding CHEN Dong ZHANG Yong Hong 2014Biomedical and Environmental Sciences2014,27,12:12
7Comparison of Long-term Outcomes in Patients with Premature Triple-vessel Coronary Disease Undergoing Three Different Treatment Strategies: A Prospective Cohort Study显示文摘Jing-Jing Xu Yin Zhang Lin Jiang Jian Tian Lei Song Zhan Gao Xin-Xing Feng Xue-Yan Zhao Yan-Yan Zhao Dong Wang Kai Sun Lian-Jun Xu Ru Liu Run-Lin Gao Bo Xu Lei Song Jin-Qing Yuan 2018Chinese Medical Journal2018,,1:10
8Expert Consensus on Clinical Diagnostic Criteria for Fatal Familial Insomnia显示文摘Li-Yong Wu Shu-Qin Zhan Zhao-Yang Huang Bin Zhang Tao Wang Chun-Feng Liu Hui Lu Xiao-Ping Dong Zhi-Ying Wu Jie-Wen Zhang Ji-Hui Zhang Zhong-Xin Zhao Fang Han Yah Huang Jun Lu Serge Gauthier Jian-Ping Jia Yu-Ping Wang 2018Chinese Medical Journal2018,,13:10
9NUMERICAL MODELING OF WAVE EVOLUTION AND RUNUP IN SHALLOW WATER显示文摘Based on the Navier-Stokes (N-S) equations for viscous, incompressible fluid and the VOF method, 2-D and 3-D Numerical Wave Tanks (NWT) for nonlinear shallow water waves are built. The dynamic mesh technique is applied, which can save computational resources dramatically for the simulation of solitary wave propagating at a constant depth. Higher order approximation for cnoidal wave is employed to generate high quality waves. Shoaling and breaking of solitary waves over different slopes are simulated and analyzed systematically. Wave runup on structures is also investigated. The results agree very well with experimental data or analytical solutions.DONG Zhi ZHAN Jie-min 2009Journal of Hydrodynamics2009,21,6:8
10Specific HLA-DQB1 alleles associated with risk for development of hepatocellular carcinoma:A meta-analysis显示文摘AIM:To evaluate the association of human leukocyte antigen(HLA)-DQB1 alleles with hepatocellular carcinoma(HCC) through meta-analysis of published data.METHODS:Case-control studies on HLA-DQB1 allele association with HCC published up to January 2010 were included in the analyses.The odds ratios(ORs) of HLADQB1 allele distributions in HCC patients were analyzed and compared with healthy controls.The meta-analysis software REVMAN 5.0 was applied for investigating heterogeneity among individual studies and for summarizing all the studies.A meta-analysis was performed using fixed-effect or random-effect methods,depending on the absence or presence of significant heterogeneity.Seven case-control studies containing 398 cases and 594 controls were included in the final analysis.RESULTS:Among the five family alleles,two(DQB1*02 and DQB1*03) were found to be significantly associated with the risk of HCC.The combined OR for the association of DQB1*02 and DQB1*03 allele with the risk for HCC was 1.78(95% CI:1.05-3.03,P = 0.03) and 0.65(95% CI:0.48-0.89,P = 0.007),respectively.Among the 13 specific alleles,two(DQB1*0502 and DQB1*0602) were significantly associated with risk of HCC.The combined OR for the association of DQB1*0502 and DQB1*0602 allele with the risk for HCC was 1.82(95% CI:1.14-2.92,P = 0.01) and 0.58(95% CI:0.36-0.95,P = 0.03),respectively.No significant association was established for other HLA-DQB1 family alleles and specific alleles.CONCLUSION:Our results support the hypothesis that specific HLA-DQB1 allele families and alleles might influence the susceptibility or resistance to HCC,although it needs further investigations.Yong-Ning Xin Zhong-Hua Lin Xiang-Jun Jiang Shu-Hui Zhan Quan-Jiang Dong Qing Wang Shi-Ying Xuan 2011World Journal of Gastroenterology2011,17,17:8
11Antioxidant Activities of Aqueous Extract from Cultivated Fruit-bodies of Cordyceps militaris (L.) Link In Vitro显示文摘从植物和真菌提取的生物抗氧化剂有潜在的能力清除释放激进分子并且禁止类脂化合物 peroxidation,在阻止疾病的玩的重要角色例如,癌症,和老化由反应的氧种类导致了,它可以引起氧化损坏到 DNA,蛋白质和另外的大分子。Cordyceps militaris (L.) 的栽培水果身体的抗氧化剂力量连接在这研究被调查。五在 vitro 证实系统被采用,包括 1,1-diphenyl-2-picryldrazyl (DPPH ) 清除的自由的基,消除的氢氧根基,铁 chelating,罂酸的酸类脂化合物 peroxidation 的抑制和减少的力量。从栽培水果身体的水的摘录受到氨基酸,多糖和甘露糖醇的测试。维生素酸(Vc ) , butylated hydroxytoluene (BHT ) 和 ethylenediaminetetraacetic 酸(EDTA ) 为比较被用作积极控制。在试金之中, C 的水的摘录。militaris 水果身体在 DPPH 上显示出重要清除效果,消除氢氧根激进分子上的能力和铁的铁上的 chelating 效果。摘录也显示出禁止罂酸的酸类脂化合物 peroxidation 并且减少力量的积极结果。Yu Zhan Cai-Hong Dong Yi-Jian Yao 2006Journal of Integrative Plant Biology2006,48,11:7
12Paleotopographic controls on facies development in various types of braid-delta depositional systems in lacustrine basins in China显示文摘Braid-delta depositional systems are widely developed in most continental basins in China.Research indicates that,for different types of braid delta,the facies sequence and association,which are critical to the prediction of the distribution of reservoirs,differ greatly.This study illustrates the differences in braid-delta depositional systems in terms of sedimentary characteristics,associated systems and reservoir distributions using three typical paleodeltas in western China:the Zhenbei delta of the upper Triassic Yanchang Formation in the Ordos Basin,the Yuanba delta of the upper Triassic Xujiahe Formation in the Sichuan Basin and the Jimsar delta of the upper Permian Wutonggou Formation in the Junggar Basin.A stratigraphic framework was established using seismic data,logs and cores by choosing stable mud sections as regional correlation markers and,topographies of these deltas were reconstructed based on the decompaction and paleobathymetric corrections.Based on both the paleotopography of these deltas and the differences of their sedimentary facies,these braided deltas can be classified into two systems:steep-gradient braid-delta-turbidite system and low-gradient braid-delta-lacustrine system.Moreover,the low-gradient braid-delta-lacustrine system can be further divided into interfingered and sharp contact sub-types according to the contact relation between the delta sands and lacustrine muds.This study shows that the paleotopography of basin margins strongly controls the accommodation as braid deltas prograde into lacustrine basins and,influences the location of the shoreline in response to changes in the lake level.Furthermore,paleotopography plays a significant role in facies and reservoir distribution which is important for petroleum exploration and development.Dong Feng Hongwen Deng Zhan Zhou Xiaopeng Gao Longtao Cui 2015Geoscience Frontiers2015,6,4:7
13Urinary metabolomics analysis identifies key biomarkers of different stages of nonalcoholic fatty liver disease显示文摘AIM To identify a panel of biomarkers that can distinguish between non-alcoholic fatty liver disease(NAFLD) and non-alcoholic steatohepatitis(NASH), and explore molecular mechanism involved in the process of developing NASH from NAFLD.METHODS Biomarkers may differ during stages of NAFLD. Urine and blood were obtained from non-diabetic subjects with NAFLD and steatosis, with normal liver function(n = 33), from patients with NASH, with abnormal liver function(n = 45), and from healthy age and sex-matched controls(n = 30). Samples were subjected to metabolomic analysis to identify potential non-invasive biomarkers. Differences in urinary metabolic profiles were analyzed using liquid chromatography tandem mass spectrometry with principal component analysis and partial least squares-discriminate analysis.RESULTS Compared with NAFLD patients, patients with NASH had abnormal liver function and high serum lipid concentrations. Urinary metabonomics found differences in 31 metabolites between these two groups, including differences in nucleic acids and amino acids. Pathway analysis based on overlapping metabolites showed that pathways of energy and amino acid metabolism, as well as the pentose phosphate pathway, were closely associated with pathological processes in NAFLD and NASH.CONCLUSION These findings suggested that a panel of biomarkers could distinguish between NAFLD and NASH, and could help to determine the molecular mechanism involved in the process of developing NASH from NAFLD. Urinary biomarkers may be diagnostic in these patients and could be used to assess responses to therapeutic interventions.Shu Dong Zong-Ying Zhan Hong-Yan Cao Chao Wu Yan-qin Bian Jian-Yuan Li Gen-Hong Cheng Ping Liu Ming-Yu Sun 2017World Journal of Gastroenterology2017,23,15:7
14Lung-protective Ventilation in Patients with Brain Injury: A Multicenter Cross-sectional Study and Questionnaire Survey in China显示文摘Xu-Ying Luo Ying-Hong Hu Xiang-Yuan Cao Yan Kang Li-Ping Liu Shou-Hong Wang Rong-Guo Yu Xiang-You Yu Xia Zhang Bao-Shan Li Zeng-Xiang Ma Yi-Bing Weng Heng Zhang De-Chang Chen Wei Chen Wen-Jin Chen Xiu-Mei Chen Bin Du Mei-Li Duan Jin Hu Yun-Feng Hoang Gui-Jun Jia Li-Hong Li Yu-Min Liang Bing-Yu Qin Xian-Dong Wang Jian Xiong Li-Mei Yan Zheng-Ping Yang Chen-Ming Dong Dong-Xin Wang Qing-Yuan Zhan Shuang-Lin FU Lin Zhao Qi-Bing Huang Ying-Guang Xie Xiao-Bo Huang Guo-Bin Zhang Wang-Bin Xu Yuan Xu YaLing Liu He-Ling Zhao Rong-Qing Sun Ming Sun Qing-Hong Cheng Xin Qu Xiao-Feng Yang Ming Xu Zhong-Hua Shi Han Chen Xuan He Yan-Lin Yang Guang-Qiang Chen Xiu-Mei Sun Jian-Xin Zhou 2016Chinese Medical Journal2016,,14:6
15Intercritical Rolling Induced Ultrafine Lamellar Structure and Enhanced Mechanical Properties of Medium-Mn Steel显示文摘The medium-Mn steel with ferrite and austenite structure was rolled in the intercritical region down to different rolling reduction.The microstructure and mechanical properties of the rolled steels were investigated by scanning electron microscopy,transmission electron microscopy,X-ray diffraction and tensile tests.It was found that the ferrite and austenite structure gradually evolved into an ultrafine structure from the random directional lath structure to lamellar structure with lath longitudinal direction parallel to the rolling direction with increasing rolling strain.It was found that the thickness of the laths was gradually refined with increasing rolling strain.The lath thickness is about0.15μm stored with high density dislocations and the austenite volume fraction of the steel is about 24%after 80%rolling reduction.Furthermore,it was interesting to find that yield strength,tensile strength and total elongation of the 80%rolled medium-Mn steel are about 1 000MPa,1 250MPa and 24%,respectively,demonstrating an excellent combination of the strength and ductility.Based on the microstructure examination,it was proposed that the grain refinement of the medium-Mn steels could be attributed to the duplex structure and the low rolling temperature.Analysis of the relationship between the microstructure and the mechanical properties indicated that the high yield strength mainly resulted from the ultrafine grain size and the high density dislocation,but the improved ductility may be attributed to the large fractions of austenite retained after intercritical rolling.Wei ZHAN Li-qiang CAO Jun HU Wen-quan CAO Jian LI Han DONG 2014Journal of Iron and Steel Research(International)2014,21,5:6
16FAT1, a direct transcriptional target of E2F1, suppresses cell proliferation, migration and invasion in esophageal squamous cell carcinoma显示文摘Objective: Growing evidence indicates that FAT atypical cadherin 1(FAT1) has aberrant genetic alterations and exhibits potential tumor suppressive function in esophageal squamous cell carcinoma(ESCC). However, the role of FAT1 in ESCC tumorigenesis remains not well elucidated. The aim of this study was to further investigate genetic alterations and biological functions of FAT1, as well as to explore its transcriptional regulation and downstream targets in ESCC.Methods: The mutations of FAT1 in ESCC were achieved by analyzing a combined study from seven published genomic data, while the copy number variants of FAT1 were obtained from an analysis of our previous data as well as of The Cancer Genome Atlas(TCGA) and Cancer Cell Line Encyclopedia(CCLE) databases using the cBioPortal. The transcriptional regulation of FAT1 expression was investigated by chromatin immunoprecipitation(ChIP) and the luciferase reporter assays. In-cell western, Western blot and reverse transcription-quantitative polymerase chain reaction(RT-qPCR) were used to assess the indicated gene expression. In addition, colony formation and Transwell migration/invasion assays were employed to test cell proliferation, migration and invasion.Finally, RNA sequencing was used to study the transcriptomes.Results: FAT1 was frequently mutated in ESCC and was deleted in multiple cancers. Furthermore, the transcription factor E2 F1 occupied the promoter region of FAT1, and depletion of E2 F1 led to a decrease in transcription activity and mRNA levels of FAT1. Moreover, we found that knockdown of FAT1 promoted KYSE30 and KYSE150 cell proliferation, migration and invasion;while overexpression of FAT1 inhibited KYSE30 and KYSE410 cell proliferation, migration and invasion. In addition, knockdown of FAT1 led to enrichment of the mitogen-activated protein kinase(MAPK) signaling pathway and cell adhesion process.Conclusions: Our data provided evidence for the tumor suppressive function of FAT1 in ESCC cells and elucidated the transcriptional regulation of FAT1 by E2 F1, which may facilitate the understanding of molecular mechanisms of the progression of ESCC.Yu Wang Guangchao Wang Yunping Ma Jinglei Teng Yan Wang Yongping Cui Yan Dong Shujuan Shao Qimin Zhan Xuefeng Liu 2019Chinese Journal of Cancer Research2019,31,4:6
17Magnetic manganese-based composites with multiple loss mechanisms towards broadband absorption显示文摘The weak dielectric properties and the lack of magnetic loss of manganese-based absorbers are obstructed as the new generation of electromagnetic wave absorption(EMA)materials applying in microelectronic devices.Herein,the sulfuration and subsequent compounding strategies have been employed to enhance the EMA performance of multi-shell nanosphere-shaped Mn_(2)O_(3)materials.With the narrow bandgap,the as-obtained MnS possesses reinforced electrical conductivity,which is conducive to conductivity loss.More importantly,the presence of potential difference between different phases will form space charge region at the heterogeneous interface,thus favoring interfacial polarization.Additionally,the improvement of magnetic loss is attributed to the presence of Co_(3)O_(4)nanoparticles.Consequently,the composites present enhanced EMA performance than original Mn_(2)O_(3).Specifically,the minimum reflection loss of as-prepared composites is−51.4 dB at the thickness of 1.8 mm and the broad effective absorption bandwidth reaches 6.2 GHz at 1.9 mm.The low matching thickness and high absorption efficiency in this work can provide a convincing reference when designing distinguished manganese-based absorbers.Yue Liu Zirui Jia Qianqian Zhan Yuhao Dong Qimeng Xu Guanglei Wu 2022Nano Research2022,15,6:6
18Genesis of Yangla Banded Skarn-Hosted Copper Deposit in Tethys Orogenic Belt of Southwestern China显示文摘INTRODUCTIONTheYanglacopperdepositishostedbybandedskarn,whichwastraditionalyconsideredtohavebeenformedbycontactmetasomaticpro...Zhan Mingguo Lu Yuanfa Yichang Institute of Geology and Mineral Resources, CAGS, Yichang 443003 Dong Fangliu Department of Geology and Mineral Resources, China University of Geosciences, Beijing 100083 Chen Kaixu Wei Junqi Yichang Institute of 1999Journal of Earth Science1999,18,1:6
19Analysis of the Expression of Angioarchitecture-related Factors in Patients with Cerebral Arteriovenous Malformation显示文摘Guang-Zhong Chen Yu Ke Kun Qin Meng-Qi Dong Shao-Jian Zeng Xiao-Feng Lin Sheng-Quan Zhan Kai Tang Chao Peng Xiao-Wen Ding Dong Zhou 2017Chinese Medical Journal2017,,20:5
20Cdk phosphorylation licenses Kif4A chromosome localization required for early mitotic progression显示文摘Zhixiong Dong Changjun Zhu Qimin Zhan Wei Jiang 2018Journal of Molecular Cell Biology2018,10,4:5
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