|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Overtopping breaching of cohesive homogeneous earth dam with different cohesive strength显示文摘In consideration of the range of clay content of Chinese earth dams, the world's highest prototype tests have been made to research on the effects of cohesive strength of filling of cohesive homogeneous earth dam on breach formation. Three breach mechanisms were presented, they were the source-tracing erosion of dam body with the form of 'multilevel headcut', 'two-helix flow' erosion of dam crest and collapse of breach sidewalls due to instability. It can be concluded that the cohesive strength of filling of earth dam has great effect on breach formation. When the cohesive strength is bigger, the breach process becomes slower, and the peak outflow and the final width and depth of breach become smaller. The main character of the breach formation is head cutting and dumping collapse. When the cohesive strength is smaller, the breach process becomes faster, and the peak outflow, the final width and depth of breach become bigger. The main character of the breach formation is single level head cutting and shearing collapse. | ZHANG JianYun LI Yun XUAN GuoXiang WANG XiaoGang LI Jun | 2009 | Science China(Technological Sciences)2009，52，10： | 34 |
| 2 | Interface issues of lithium metal anode for high-energy batteries: Challenges, strategies, and perspectives显示文摘Lithium(Li)metal is considered as one of the most promising anode materials for next-generation high-energy-density storage systems.However,the practical application of Li metal anode is hindered by interfacial instability and air instability due to the highly reactivity of Li metal.Unstable interface in Li metal batteries(LMBs)directly dictates Li dendrite growth,“dead Li”and low Coulombic efficiency,resulting in inferior electrochemical performance of LMBs and even safety issues.In addition,its sensitivity to ambient air leads to the severe corrosion of Li metal anode,high requirements of production and storage,and increased manufacturing cost.Plenty of efforts in recent years have overcome many bottlenecks in these fields and hastened the practical applications of high-energy-density LMBs.In this review,we focus on emerging methods of these two aspects to fulfill a stable and low cost electrode.In this perspective,design artificial solid electrolyte interphase(SEI)layers,construct three-dimensional conductive current collectors,optimize electrolytes,employ solid-state electrolytes,and modify separators are summarized to be propitious to ameliorate interfacial stability.Meanwhile,ex situ/in situ formed protective layers are highlighted in favor of heightening air stability.Finally,several possible directions for the future research on advanced Li metal anode are addressed. | Yiyao Han Bo Liu Zhen Xiao Wenkui Zhang Xiuli Wang Guoxiang Pan Yang Xia Xinhui Xia Jiangping Tu | 2021 | InfoMat2021，3，2： | 11 |
| 3 | A comparison of the biological,geological events and environmental backgrounds between the Neoproterozoic-Cambrian and Permian-Triassic transitions显示文摘The Neoproterozoic-Cambrian(N-C) and Permian-Triassic(P-T) transitions have been regarded the two most critical transitions in earth history because of the explosive biological radiation in the early Cambrian(the Cambrian Explosion) and the largest mass extinction at the end-Permian.Previous studies suggest that these two critical transitions showed certain comparability in major evolutionary events.In other words,a series of biological,geological,and geochemical events that had happened in the N-C transition occurred repeatedly during the P-T transition.Those events included continental re-configuration related to the deep mantle dynamics,global-scale glaciations,large C-,Sr-,and S-isotope perturbations indicating atmospheric and oceanic changes,abnormal precipitation of carbonates,and associated multiple biological radiations and mass extinctions.The coupling of those events in both N-C and P-T transitions suggests that deep mantle dynamics could be a primary mechanism driving dramatic changes of environment on the earth's surface,which in turn caused major biological re-organizations.A detailed comparison of those events during the two critical transitions indicates that despite their general comparability,significant differences do exist in magnitude,duration,and frequency.The supercontinent Rodinia began to rift before the Snowball Earth time.By contrast,the supercontinent Pangea entered the dispersal stage after the greatest glaciation from the Late Carboniferous to Cisuralian.Quantitative data and qualitative analyses of different fossil groups show a more profound mass extinction during the N-C transition than at the end-Permian in terms of ecosystem disruption.This is indicated by the disappearance of the whole Ediacaran biota at the N-C boundary.The subsequent appearances of many new complex animals at phylum level in the early Cambrian mark the establishment of a brand new ecosystem.However,the end-Permian mass extinction is manifested mainly by the extinction of many different taxa at class and order levels.Although it caused the extinction of 95% of marine species and 75% of terrestrial species as well as complete cessation of coal and reef deposits after the mass extinction,this high-level biological re-organization still occurred within an established ecosystem,however drastic it may seem.Survived or Lazarus taxa re-occupied the existing ecospace in a relatively short duration after the end-Permian mass extinction.C-isotope excursions display large perturbations during both transitions,yet also in different magnitudes and frequencies,which suggest different atmospheric and oceanic conditions.The recurrent geological and geochemical events as well as the coupled major biological turnovers during the two transitions provide new clues to understanding the interplays among the earth-life system.Thus,it is essential to carry out multidisciplinary studies from the deep internal system to the surface of the Earth as a whole in order to unravel the interactions of different spheres of the earth. | ShuZhong Shen MaoYan Zhu XiangDong Wang GuoXiang Li ChangQun Cao Hua Zhang | 2010 | Science China Earth Sciences2010，53，12： | 9 |
| 4 | The wheat MYB-related transcription factor TaMYB72 promotes flowering in rice显示文摘Through large-scale transformation analyses, Ta MYB72 was identified as a flowering time regulator in wheat. Ta MYB72 is a MYB family transcription factor localized to the nucleus. Three Ta MYB72 homologs,Ta MYB72-A, Ta MYB72-B and Ta MYB72-D, cloned from hexaploid wheat were mapped to the short arm of the group 6 chromosomes. Under the long-day conditions,over-expression of the Ta MYB72 in rice shortened the flowering time by approximately 12 d. Expression analyses suggest that Ta MYB72 may function through upregulation of florigen genes Hd3 a and RFT1. | Lichao Zhang Guoxiang Liu Jizeng Jia Guangyao Zhao Chuan Xia Lina Zhang Fu Li Qiang Zhang Chunhao Dong Shuangcheng Gao Longzhi Han Xiuping Guo Xin Zhang Jinxia Wu Xu Liu Xiuying Kong | 2016 | Journal of Integrative Plant Biology2016，58，8： | 8 |
| 5 | Cambrian integrative stratigraphy and timescale of China显示文摘The Cambrian Period is the first period of the Phanerozoic Eon and witnessed the explosive appearance of the metazoans, representing the beginning of the modern earth-life system characterized by animals in contrary to the Precambrian earth-life system dominated by microbial life. However, understanding Cambrian earth-life system evolution is hampered by regional and global stratigraphic correlations due to an incomplete chronostratigraphy and consequent absence of a highresolution timescale. Here we briefly review the historical narrative of the present international chronostratigraphic framework of the Cambrian System and summarize recent advances and problems of the undefined Cambrian stage GSSPs, in particular we challenge the global correlation of the GSSP for the Cambrian base, in addition to Cambrian chemostratigraphy and geochronology. Based on the recent advances of the international Cambrian chronostratigraphy, revisions to the Cambrian chronostratigraphy of China, which are largely based on the stratigraphic record of South China, are suggested, and the Xiaotanian Stage is newly proposed for the Cambrian Stage 2 of China. We further summarize the integrative stratigraphy of South China, North China and Tarim platforms respectively with an emphasis on the facies variations of the Precambrian-Cambrian boundary successions and problems for identification of the Cambrian base in the different facies and areas of China. Moreover, we discuss stratigraphic complications that are introduced by poorly fossiliferous dolomite successions in the upper Cambrian System which are widespread in South China, North China and Tarim platforms. | Maoyan ZHU Aihua YANG Jinliang YUAN Guoxiang LI Junming ZHANG Fangchen ZHAO Soo-Yeun AHN Lanyun MIAO | 2019 | Science China Earth Sciences2019，62，1： | 8 |
| 6 | Medical expenditures for colorectal cancer diagnosis and treatment: A 10-year high-level-hospital-based multicenter retrospective survey in China, 2002-2011显示文摘Objective: Colorectal cancer(CRC) causes a substantial burden of disease in China and the evidence of economic burden triggered is fundamental for priority setting. The aim of this survey was to quantify medical expenditures and the time trends for CRC diagnosis and treatment in China.Methods: From 2012 to 2014, a hospital-based multicenter retrospective survey was conducted in 13 provinces across China. For each eligible CRC patient diagnosed from 2002 to 2011, clinical information and expenditure data were extracted using a uniform questionnaire. All expenditure data were reported in Chinese Yuan(CNY)using 2011 values.Results: Of the 14,536 CRC patients included, the average age at diagnosis was 58.2 years and 15.8% were stageI cases. The average medical expenditure per patient was estimated at 37,902 CNY [95 % confidence interval(95%CI): 37,282-38,522], and the annual average increase rate was 9.2% from 2002 to 2011(P for trend <0.001), with a cumulative increase of 2.4 times(from 23,275 CNY to 56,010 CNY). The expenditure per patient in stages Ⅰ, Ⅱ, Ⅲ and Ⅳ were 31,698 CNY, 37,067 CNY, 38,918 CNY and 42,614 CNY, respectively(P<0.001). Expenditure significantly differed within various subgroups. Expenses for drugs contributed the largest proportion(52.6%).Conclusions: These conservative estimates illustrated that medical expenditures for CRC diagnosis and treatment in tertiary hospitals in China were substantial and increased rapidly over the 10 years, with drugs continually being the main expense by 2011. Relatively, medical expenditures are lower for CRC in the earlier stages. These findings will facilitate the economic evaluation of CRC prevention and control in China. | Jufang Shi Guoxiang Liu Hong Wang Ayan Mao Chengcheng Liu Lanwei Guo Huiyao Huang Jiansong Ren Xianzhen Liao Yana Bai Xiaojie Sun Xinyu Zhu Jialin Wang Bingbing Song Jinyi Zhou Lin Zhu Haike Lei Yuqin Liu Yunyong Liu Lingbin Du Yutong He Kai Zhang Ni Li Wanqing Chen Min Dai Jie He | 2019 | Chinese Journal of Cancer Research2019，31，5： | 8 |
| 7 | Early Cambrian eodiscoid trilobites of the Yangtze Platform and their stratigraphic implications显示文摘Analysis of the taxonomy and stratigraphic distribution of the Early Cambrian eodiscoid trilobites of the Yangtze Platform indicates that species of Tsunyidiscus and Hupeidiscus can be used for biostratigraphic correlation. T. aclis occurs only in the lower Qiongzhusian, T. armatus occurs in the lower and middle Qiongzhusian, while T. niutitangensis and T. tingi occur mainly in the middle and upper Qiongzhusian, with only T. tingi extending upward into the lower Canglangpuian. H. orientalis first appears in the upper Qiongzhusian, reaching peak abundance in the lower Canglangpuian and becoming extinct above the Drepanuroides Zone. Biostratigraphic and lithostratigraphic correlations indicate that the limestone in the lower part of the Mingxinsi Formation, the Upper Member of Jiumenchong Formation, and the upper part of the Middle Member of the Huangbailing Formation, can be correlated with each other as Hupediscus, an index fossil of the lower Canglangpuian, is abundant in all these units. The lower part of the Niutitang and Jiumenchong formations in eastern Guizhou, which mainly represent Qiongzhusian strata, can be correlated with the Lower Member of the Huangbailing Formation. The basal part of the Niutitang Formation, which may be equivalent to the Upper Meishucunian Shiyantou Formation in eastern Yunnan, is very condensed. Well-preserved sponge faunas and non-mineralized fossils in the lower part of the Niutitang and Hetang formations are not older than Qiongzhusian in age. | YANG Aihua, ZHU Maoyan*, ZHANG Junming and LI Guoxiang(Nanjing Institute of Geology and Palaeontology, Chinese Academy of Sciences, Nanjing 210008, China) | 2003 | Progress in Natural Science:Materials International2003，13，11： | 7 |
| 8 | Hydrodynamic analysis of clastic injection and hydraulic fracturing structures in the Jinding Zn-Pb deposit,Yunnan,China显示文摘Jinding Zn-Pb 存款通常被考虑了以一个相对被动的方法从传播 basinal 液体形成了,与液体流动被结构和沉积外形正在控制,类似于许多另外的招待沉积的底金属存款。然而,几最近的研究在 Jinding 存款的开的坑揭示了沙注射结构,恼人的角砾岩,和水力的破裂的存在并且建议存款从 overpressured 液体的爆炸版本被形成。这研究报导液体的新观察过压相关从地下的活动方式(Paomaping 和 Fengzishan ) 组织,它比在开的坑显示出更清楚的横切的关系。观察结构包括:1 ) 沙(楳湧晩捩湡汴 ? 潣瑮楲畢整琠? 桴 ? 潴慴? 票牤 ' 夷典? | Guoxiang Chi Chunji Xue Hairuo Qing Wei Xue Jiangwei Zhang Yunqiang Sun | 2012 | Geoscience Frontiers2012，3，1： | 5 |
| 9 | Stress protein expression in early phase spinal cord ischemia/reperfusion injury显示文摘Spinal cord ischemia/reperfusion injury is a stress injury to the spinal cord. Our previous studies using differential proteomics identified 21 differentially expressed proteins (n > 2) in rabbits with spinal cord ischemia/reperfusion injury. Of these proteins, stress-related proteins included protein disulfide isomerase A3, stress-induced-phosphoprotein 1 and heat shock cognate protein 70. In this study, we established New Zealand rabbit models of spinal cord ischemia/reperfusion injury by abdominal aorta occlusion. Results demonstrated that hind limb function initially improved after spinal cord ischemia/reperfusion injury, but then deteriorated. The pathological morphology of the spinal cord became aggravated, but lessened 24 hours after reperfusion. However, the numbers of motor neurons and interneurons in the spinal cord gradually decreased. The expression of protein disulfide isomerase A3, stress-induced-phosphoprotein 1 and heat shock cognate protein 70 was induced by ischemia/reperfusion injury. The expression of these proteins increased within 12 hours after reperfusion, and then decreased, reached a minimum at 24 hours, but subsequently increased again to similar levels seen at 6-12 hours, showing a characterization of induction-inhibition-induction. These three proteins were expressed only in cytoplasm but not in the nuclei. Moreover, the expression was higher in interneurons than in motor neurons, and the survival rate of interneurons was greater than that of motor neurons. It is assumed that the expression of stress-related proteins exhibited a protective effect on neurons. | Shanyong Zhang Dankai Wu Jincheng Wang Yongming Wang Guoxiang Wang Maoguang Yang Xiaoyu Yang | 2013 | Neural Regeneration Research2013，8，24： | 4 |
| 10 | Detecting land subsidence near metro lines in the Baoshan district of Shanghai with multi-temporal interferometric synthetic aperture radar显示文摘Land subsidence is a major factor that affects metro line(ML) stability. In this study, an improved multitemporal interferometric synthetic aperture radar(InSAR)(MTI) method to detect land subsidence near MLs is presented. In particular, our multi-temporal InSAR method provides surface subsidence measurements with high observation density. The MTI method tracks both point-like targets and distributed targets with temporal radar backscattering steadiness. First, subsidence rates at the point targets with low-amplitude dispersion index(ADI) values are extracted by applying a least-squared estimator on an optimized freely connected network. Second, to reduce error propagation, the pixels with high-ADI values are classified into several groups according to ADI intervals and processed using a Pearson correlation coefficient and hierarchical analysis strategy to obtain the distributed targets. Then,nonlinear subsidence components at all point-like and distributed targets are estimated using phase unwrapping and spatiotemporal filtering on the phase residuals. The proposed MTI method was applied to detect land subsidence near MLs of No. 1 and 3 in the Baoshan district of Shanghai using 18 TerraSAR-X images acquired between April 21,2008 and October 30, 2010. The results show that the mean subsidence rates of the stations distributed along the two MLs are-12.9 and-14.0 mm/year. Furthermore, three subsidence funnels near the MLs are discovered through the hierarchical analysis. The testing results demonstrate the satisfactory capacity of the proposed MTI method in providing detailed subsidence information near MLs. | Tao Li Guoxiang Liu Hui Lin Rui Zhang Hongguo Jia Bing Yu | 2014 | Journal of Modern Transportation2014，22，3： | 4 |
| 11 | Image segmentation algorithm for greenhouse cucumber canopy under various natural lighting conditions显示文摘In this study,machine vision technology was used to capture images of greenhouse cucumber canopy,and image segmentation was implemented under various natural lighting conditions.The images were enhanced by multi-scale retinex with color restore(MSRCR),and the MSRCR images were segmented by four algorithms:normalized difference index(NDI),excess green(ExG),modified excess green(MExG),and modified excess green minus excess red(MExG-ExR).The results indicated that compared with the original images,under various lighting conditions,the average evaluation indexes of brightness,information entropy,average gradient and mean gray value of the MSRCR images were increased by 38.71%,8.04%,4.54%,and 37.81%,respectively,and only the contrast degree decreased by 12.13%.The MExG-ExR segmentation algorithm was used to segment the MSRCR images(fifty images under various lighting conditions in the test and it performed best among the four segmentation algorithms,average overlap ratios and recognition rates of were 99.28%and 98.91%,respectively,while 38.39%and 37.95%respectively for original image.These results indicated that the MExG-ExR segmentation algorithm applied to a MSRCR canopy image produced the most stable results among the four algorithms.By using the MSRCR image enhancement algorithm,the interference of lighting on greenhouse cucumber canopy images was reduced and the foundation for achieving accurate segmentation of a canopy region was laid,which is of great significance for greenhouse cucumber phenotypic parameter measurements. | Sun Guoxiang Li Yongbo Wang Xiaochan Hu Guyue Wang Xuan Zhang Yu | 2016 | International Journal of Agricultural and Biological Engineering2016，9，3： | 4 |
| 12 | Monitoring subsidence rates along road network by persistent scatterer SAR interferometry with high-resolution TerraSAR-X imagery显示文摘Ground subsidence is one of the key factors damaging transportation facilities,e.g.,road networks consisting of highways and railways.In tiiis paper,we propose to apply the persistent scatterer synthetic aperture radar interferometry(PS-InSAR)approach mat uses highresolution TerraSAR-X(TSX)imagery to extract the regional scale subsidence rates(i.e.,average annual subsidence in mm/year)along road networks.The primary procedures involve interferometric pair selection,interferogram generation,persistent scatterer(PS)detection,PS networking,phase parameterization,and subsidence rate estimation.The Xiqing District in southwest Tianjin(China)is selected as the study area.This district contains one railway line and several highway lines.A total of 15TSX images covering this area between April 2009 and June 2010 are utilized to obtain the subsidence rates by using the PS-InSAR(PSI)approach.The subsidence rates derived from PSI range from—68.7 to—1.3 mm/year.These findings show a significantly uneven subsidence pattern along the road network.Comparison between the PSI-derived subsidence rates and the leveling data obtained along the highways shows that the mean and standard deviation(SD)of the discrepancies between die two types of subsidence rates are 0.1 and±3.2 mm/year,respectively.The results indicate that the high-resolution TSX PSI is capable of providing comprehensive and detailedsubsidence information regarding road networks with millimeter-level accuracy.Further inspections under geological conditions and land-use categories in the study area indicate that the observed subsidence is highly related to aquifer compression due to groundwater pumping.Therefore,measures should be taken to mitigate groundwater extraction for the study area. | Bing Yu Guoxiang Liu Rui Zhang Hongguo Jia Tao Li Xiaowen Wang Keren Dai Deying Ma | 2013 | Journal of Modern Transportation2013，21，4： | 4 |
| 13 | Metal-Metal Cooperation in Dinucleating Complexes Involving Late Transition Metals Directed towards Organic Catalysis显示文摘Cooperatively bimetallic organic catalysis,coupling actions of two metal centers in a catalytic organic transformation via co-activation of a single molecule or synergistic activation of two molecules,has witnessed rapid development in the last decades. | Ni Xiong Guoxiang Zhang Xiaolong Sun Rong Zeng | 2020 | Chinese Journal of Chemistry2020，38，2： | 4 |
| 14 | Circadian clock gene expression regulates cancer cell growth through glutaminase显示文摘夫酸安是为恶意的肿瘤房间的必要氨基酸。使夫酸安产生代射变化的 Glutaminase 到达肿瘤立即在最大的增长前评估的最大的 expressionin。肿瘤房间在日子期间以不同的率成长。我们 postulatedthat 在肿瘤房间的 glutaminase 的活动服从于生理节奏的钟基因的规定。我们测量了由在在六 equispaced 时间的肝和 tumorcells 的即时聚合酶链反应的西方的污点分析和生理节奏的钟基因表示削尖的 glutaminaseby 在一张 12/12 h 光 / 黑暗时间表的单个鼠标今日。结果显示出 thatthe 忍受肿瘤的鼠标,在正常下面日报条件,生理节奏地被乘火车,由正常主机 locomotoractivity 节奏和有韵律的肝钟基因表示思考了。在这些老鼠以内的肿瘤生理节奏地也被组织,由生理节奏的钟基因(Bmal1 ) 的 asreflected 表示。是很显著的的,是肾类型 glutaminase 也在一样的模式 withtumor 显示出生理节奏的节奏在肝癌症异种皮移植模型的生理节奏的钟基因表示,有条件地显示那禁止 glutaminaseactivity 可以为癌症提供一个新目标治疗。 | Aixia Huang Bingbo Bao H Rex Gaskins Haijun Liu Xueli Zhang Liwen Lu Shan Gao Yihai Shi Ming Zhang Yuanzhou Shan Jing Feng Guoxiang Yao | 2014 | Acta Biochimica et Biophysica Sinica2014，46，5： | 3 |
| 15 | OsPKpa_1 encodes a plastidic pyruvate kinase that affects starch biosynthesis in the rice endosperm显示文摘Pyruvate kinase(PK) is a key enzyme in glycolysis and carbon metabolism. Here, we isolated a rice(Oryza sativa) mutant, w59, with a white-core floury endosperm. Map-based cloning of w59 identified a mutation in OsPKpa_1, which encodes a plastidic isoform of PK(PKp). OsPKpa_1 localizes to the amyloplast stroma in the developing endosperm, and the mutation of OsPKpa_1 in w59 decreases the plastidic PK activity, resulting in dramatic changes to the lipid biosynthesis in seeds. The w59 grains were also characterized by a marked decrease in starch content. Consistent with a decrease in number and size of the w59 amyloplasts, large empty spaces were observed in the central region of the w59 endosperm, atthe early grain-filling stage. Moreover, a phylogenetic analysis revealed four potential rice isoforms of OsPKp. We validated the in vitro PK activity of these OsPKps through reconstituting active PKp complexes derived from inactive individual OsPKps, revealing the heteromeric structure of rice PKps, which was further confirmed using a protein–protein interaction analysis. These findings suggest a functional connection between lipid and starch synthesis in rice endosperm amyloplasts. | Yue Cai Wenwei Zhang Jie Jin Xiaoming Yang Xiaoman You Haigang Yan Liang Wang Jie Chen Jiahuan Xu Weiwei Chen Xingang Chen Jing Ma Xiaojie Tang Fei Kong Xiaopin Zhu Guoxiang Wang Ling Jiang William Terzaghi Chunming Wang Jianmin Wan | 2018 | Journal of Integrative Plant Biology2018，60，11： | 3 |
| 16 | Adaptive immunity in the liver显示文摘 | Zongwen Shuai Miranda WY Leung Xiaosong He Weici Zhang Guoxiang Yang Patrick SC Leung M Eric Gershwin | 2016 | Cellular & Molecular Immunology2016，13，3： | 3 |
| 17 | Aberrantly expressed GFRα-1/RET in patients with lacrimal adenoid cystic carcinoma is associated with high recurrence risk:a retrospective study of 51 LACC cases显示文摘Objective:Because of the poor prognosis of lacrimal adenoid cystic carcinoma(LACC),we aimed to investigate the effects of perineural invasion(PNI)and consequent aberrations in GDNF/GFRα-1/RET protein expression on LACC recurrence.Methods:Clinicopathological data for 51 histologically confirmed patients with LACC enrolled between 2001 and 2017 were retrospectively analyzed.Hematoxylin and eosin staining was applied to assess PNI.Tissue-based immunohistochemistry(IHC)detection of GDNF,GFRα-1,and RET proteins was performed on LACC formalin-fixed,paraffin-embedded specimens.We generated semi-quantitative data of the IHC results and compared them with the clinicopathological data for the 51 patients.Results:Of the 51 patients,19(37.3%)were PNI positive.Recurrence was more common for LACC with than without PNI(73.7%vs.37.5%,P=0.01).GDNF,GFRα-1,and RET proteins were expressed in 62.7%,62.7%,and 54.9%of the 51 patients with LACC,respectively.The expression of all 3 proteins was more common in patients with than without PNI.In agreement with previous findings,PNI-associated GFRα-1 and RET positivity,as detected by IHC,remained significantly associated with recurrence,whereas GDNF expression,as detected by IHC,was not correlated with LACC recurrence.Specifically,patients with concurrent GFRα-1 and RET expression may have a high risk of PNI(89.5%positivity rate)and recurrence(84.2%positivity rate).Conclusions:PNI may contribute to LACC recurrence.The concurrent expression of GFRα-1 and RET proteins,as detected by IHC,may potentially be associated with LACC PNI and recurrence. | Lin Liu Liqiong Zhao Jie Zhang Guoxiang Song Carol LShields Ruihua Wei | 2021 | Cancer Biology & Medicine2021，18，1： | 3 |
| 18 | A novel Z-scheme CeO_(2)/g-C_(3)N_(4)heterojunction photocatalyst for degradation of Bisphenol A and hydrogen evolution and insight of the photocatalysis mechanism显示文摘CeO_(2)/g-C_(3)N_(4)heterojunction photocatalyst had been successfully fabricated through a one-step in-situ pyrolysis formation of 3D hollow CeO_(2)mesoporous nanospheres and 2D g-C_(3)N_(4)nanosheets together with simultaneous removal of carbon sphere templates after heat treatment.The sample shows high catalytic performances for photocatalytic hydrogen generation and photocatalytic oxidation of Bisphenol A(BPA)under visible light irradiation,and the catalytic degradation route of BPA was suggested by the degradation products determined by GC-MS.The enhancing catalytic activity was attributed to the effective interfacial charge migration and separation.Finally,it was proposed that the CeO_(2)/g-C_(3)N_(4)heterojunction photocatalyst could follow a more appropriate Z-scheme charge transfer mechanism,which was confirmed by the analysis of experiment and theoretical calculation results. | Wei Zhao Tiantian She Jingyi Zhang Guoxiang Wang Sujuan Zhang Wei Wei Gang Yang Lili Zhang Dehua Xia Zhipeng Cheng Haibao Huang Dennis Y.C.Leung | 2021 | Journal of Materials Science & Technology2021，，26： | 3 |
| 19 | Diagnostic value of whole-body MRI with diffusion-weighted sequence for detection of peritoneal metastases in colorectal malignancy显示文摘Objective:To assess the diagnostic accuracy of whole-body MRI using diffusion-weighted sequence(WB-DWI)to determine the peritoneal cancer index(PCI)in correlation with surgical and histopathological findings.Methods:Twenty-seven patients underwent preoperative WB-MRI,followed by cytoreductive surgery for primary tumors of the appendix(n=15),colorectum(n=12),and associated peritoneal disease.A total of 351 regions were retrospectively reviewed.The sensitivity,specificity,and accuracy were calculated at 13 anatomical sites.The WB-DWI PCI and PCI type were compared with surgical and histopathological findings.Results:No statistical difference was found between the WB-DWI PCI and surgical PCI(P=0.574).WB-DWI correctly predicted the PCI type in 24 of 27 patients with high accuracy(88.9%),including 10 of 10 patients with small-volume tumor,12 of 14 with moderate-volume tumor,and 2 of 3 with large-volume tumor.WB-DWI correctly depicted tumors in 163 of 203 regions,with 40false-negative and 23 false-positive regions.The overall sensitivity,specificity,and accuracy of WB-DWI for the detection of peritoneal tumors were 80.3%,84.5%,and 82.1%,respectively.For lesions<0.5 cm in diameter,WB-DWI demonstrated good sensitivity(69.4%).Conclusions:WB-DWI accurately predicted PCI before surgery in patients undergoing evaluation for cytoreductive surgery. | Huan Zhang Weixing Dai Caixia Fu Xu Yan Alto Stemmer Tong Tong Guoxiang Cai | 2018 | Cancer Biology & Medicine2018，15，2： | 3 |
| 20 | Improved method to raise polyclonal antibody using enhanced green fluorescent protein transgenic mice显示文摘Recombinant 熔化蛋白质广泛地被用作抗原对目标蛋白质的 epitope 提起抗体。然而,在产生抗血清的伴随物反搬运人抗体减少需要的抗体的生产并且引起讨厌的非特定的有免疫力的反应。这被建议搬运人蛋白质转基因的动物能被用来解决这个问题。验证这个假设,提高的绿荧光灯的蛋白质(EGFP ) 转基因的老鼠被生产。由与熔化蛋白质 His6HAtag-EGFP 使老鼠免疫,我们证明从转基因的老鼠的抗血清从野类型的老鼠与那相比对 EGFP 对 His6HA 标签和更低的 titer 抗体有更高的 titer 抗体。因此,这份报告描述一个改进方法用能在抗体准备有申请潜力的 EGFP 转基因的老鼠提起高 titer 反肽 polyclonal 抗体。 | Jianke Ren Long Wang Guoxiang Liu Wen Zhang Zhejin Sheng Zhugang Wang Jian Fei | 2008 | Acta Biochimica et Biophysica Sinica2008，40，2： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员