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| 1 | Coordinated peak expression of MMP-26 and TIMP-4 in preinvasive human prostate tumor显示文摘因为早察觉和治疗为病人的医药管理是批评的,为早前列腺癌症诊断的新奇简历标记的鉴定是高度重要的。在基础房间层和地下室膜的连续性的混乱为高级职业人员静电干扰 intraepithelial 瘤形成(HGPIN ) 的前进是必要的到在人的前列腺的侵略腺癌。涉及变换到侵略显型的分子是强烈审查的题目。我们以前报导了矩阵 metalloproteinase-26 (MMP-26 ) 经由地下室膜蛋白质并且由激活 MMP-9 的酶原形式的劈开支持人的前列腺癌症房间的侵略。而且,我们发现了 metalloproteinases-4 (TIMP-4 ) 的那个织物禁止者是大多数有势力 MMP-26 的内长的禁止者。这里,我们更高示威(p<0.0001 ) 在 HGPIN 和癌症的 MMP-26 和 TIMP-4 表示,与非肿瘤的 acini 相比。他们的表示层次在 HGPIN 是最高的,但是在一样的纸巾在侵略癌症(为各个的 p<0.001 ) 衰退。连续前列腺癌症织物节染色的 Immunohistochemical 建议 MMP-26 和 TIMP-4 的 colocalization。现在的学习显示 MMP-26 和 TIMP-4 可以在 HGPIN 的变换期间起一个不可分的作用到侵略癌症并且可以也为早前列腺癌症诊断用作标记。房间研究(2006 ) 16:750-758。做 i:10.1038/sj .cr.7310089;出版联机 2006 年 8 月 29 日。 | Seakwoo Lee Kevin K Desai Kenneth A Iczkowski Robert G Newcomer Kevin J WU Yun-Ge Zhao Winston W Tan Mark D Roycik Qing-Xiang Amy Sang | 2006 | Cell Research2006，16，9： | 18 |
| 2 | Calcium phosphate cements for bone engineering and their biological properties显示文摘Calcium phosphate cements(CPCs) are frequently used to repair bone defects. Since their discovery in the 1980 s, extensive research has been conducted to improve their properties, and emerging evidence supports their increased application in bone tissue engineering. Much effort has been made to enhance the biological performance of CPCs, including their biocompatibility, osteoconductivity, osteoinductivity, biodegradability,bioactivity, and interactions with cells. This review article focuses on the major recent developments in CPCs,including 3 D printing, injectability, stem cell delivery, growth factor and drug delivery, and prevascularization of CPC scaffolds via co-culture and tri-culture techniques to enhance angiogenesis and osteogenesis. | Hockin HK Xu Ping Wang Lin Wang Chongyun Bao Qianming Chen Michael D Weir Laurence C Chow Liang Zhao Xuedong Zhou Mark A Reynolds | 2017 | Bone Research2017，5，4： | 14 |
| 3 | 烟酰胺磷酸核糖基转移酶促进肺血管重塑,是肺动脉高压的治疗靶点显示文摘肺动脉高压(pulmonary arterial hypertension,PAH)是一种严重的进行性疾病,其标志之一是肺血管重塑。烟酰胺磷酸核糖基转移酶(nicotinamide phosphoribosyl transferase,NAMPT)是调节细胞内烟酰胺腺嘌呤二核苷酸水平、细胞氧化还原状态,调节组蛋白脱乙酰酶,促进细胞增殖和抑制凋亡的一种细胞酶。研究人员假设NAMPT可促进肺血管重塑, | Chen J Sysol JR Singla S Zhao S Yamamura A Valdez-Jasso D Abbasi T Shioura KM Sahni S Reddy V Sridhar A Gao H Torres J Camp SM Tang H Ye SQ Comhair S Dweik R Hassoun P Yuan JX Garcia JG Machado RF 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，2： | 10 |
| 4 | 生理性线粒体破碎是心脏适应能量需求增加的正常现象显示文摘线粒体在心脏中起着双重作用:负责满足能量需求和调节细胞凋亡。通常认为,线粒体的分裂和碎裂是病理性应激(如缺血)的结果,是线粒体质量差的指标,并导致线粒体自噬和细胞死亡。然而,最近的研究表明,抑制裂变也导致线粒体功能减弱和心脏损害,说明裂变对维持心脏和线粒体生物能量平衡十分重要。 | 刘莉 叶鹏 Coronado M Fajardo G Nguyen K Zhao M Kooiker KB Jung G Hu DQ Reddy S Sandoval E Stotland A Gottlieb RA Bernstein D | 2018 | 中华高血压杂志2018，26，1： | 2 |
| 5 | Abscisic acid inhibits type 2C protein phosphatases via the PYR/ PYL family of START proteins显示文摘 | PARK S Y FUNG P NISHIMURA N JENSEN D R FFUJII ZHAO Y LUMBA S SANTIAGO J RODRIGUES A CHOW T F | 2009 | Science2009，324，： | 1 |
| 6 | Thermal and mechanical properties of polyhedral oligomeric silsesquioxane ( POSS )/polyearbonate composites 显示文摘 | Zhao Y Q Schiraldi D A | 2005 | Polymer2005，46，11： | 1 |
| 7 | Thermal and mechanical propertiesof polyhedral oligomeric silsesquioxane(POSS)/polycarbonatecomposites显示文摘 | ZHAO Y SCHIRALDI D A | 2005 | Polymer2005，46，11： | 1 |
| 8 | Positional cloning of the mouse circadian clock gene显示文摘 | King D P Zhao Y Sangoram A M | 1997 | Cell1997，89，4： | 1 |
| 9 | Loss of Halophytism by Interference with SOS1 Expression1[W][OA]显示文摘 | Oh Dong-Ha Leidi Eduardo Zhang Quan Hwang Sung-Min Li Youzhi Quintero Francisco J Jiang Xingyu D’Urzo Matilde Paino Lee Sang Yeol Zhao Yanxiu Bahk Jeong Dong Bressan Ray A Yun Dae-Jin Pardo José M Bohnert Hans J | 2009 | Plant Physiology2009，，1： | 1 |
| 10 | Ultimate removal of phosphate from wastewater using a new class of polymeric ion exchangers显示文摘 | Zhao D Sengupta A K | 1998 | Water Res1998，32，5： | 1 |
| 11 | The pharmacokinetic behavior of the soy isoflavone metabolite S-(-) equol and its diastereoisomer R-( + )equol in healthy adults determined by using stable-isotope-labeled tracers^1-4 显示文摘 | SETCHELL K D R ZHAO Xueheng PINKY J H A | 2009 | Am J Clin Nutr2009，90，： | 1 |
| 12 | Tuned passive control of combusion instabilities using multiple Helmhohz resonators 显示文摘 | Zhao D Morgans A S | 2009 | Journal of Sound and Vibration2009，320，45： | 1 |
| 13 | RST invariant digital image watermarking based on log-polar mapping and phase correlation 显示文摘 | Zheng D Zhao J Y Saddik A E | 2003 | IEEE Transactionson Circuits and Systems for Video Technology2003，13，8： | 1 |
| 14 | Mercaptoaeetate and fatty acids exert direct and antagonistic effects on nodose neu rons via GPR40 fatty acid receptors显示文摘 | Darling R A Zhao H Kinch D | 2014 | Ajp Regulatory Inte- grative & Comparative Physiology2014，307，1： | 1 |
| 15 | RST invariant digital image watermarking based on log-polar mapping and phase correlation显示文摘 | Zheng D Zhao J Saddik A E | 2003 | IEEE Transaction on Circuits and System for Video Technology:Special Issue on Authentication Copyright Protection and Information Hi- ding2003，13，8： | 1 |
| 16 | Discovery of a novel small molecule, 1 -ethoxy -3 - ( 3,4 -methylenedioxyphenyl ) -2 -propanol, that induces apoptosis in A549 human lung cancer cells 显示文摘 | Du A Y Zhao B X Yin D L | 2005 | Bioorg Med Chem2005，13，13： | 1 |
| 17 | TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer 显示文摘 | Langerφd A Zhao H Borgan Φ | 2007 | Breast Cancer Res2007，9，3： | 1 |
| 18 | Microstructural evolution during reheating and tensile mechanical properties of thixoforged AZ91D-RE magnesium alloy prepared by squeeze casting-solid extrusion 显示文摘 | CHEN Q YUAN B a ZHAO G Z SHU D Y HU C K ZHAO Z D ZHAO Z X | 2012 | Materials Science and Engineering A2012，537，： | 1 |
| 19 | Synthesis and photoelectrochemical study of vertically aligned silicon nanowire arrays 显示文摘 | Yuan G Zhao H Liu X Hasanali Z S Zou Y Levine A Wang D | 2009 | Angewandte Ckemie2009，121，51： | 1 |
| 20 | Physical properties of CuCrO2 films prepared by pulsed laser deposition显示文摘 | LI D FANG X ZHAO A | 2010 | Vacuum2010，84，6： | 1 |
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