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| 1 | Experimental investigation on flow asymmetry in solid entrance region of a square circulating fluidized bed显示文摘To study the influence of back feeding particles on gas-solid flow in the riser, this paper investigated the flow asymmetry in the solid entrance region of a fluidized bed by particle concentration/velocity measurements in a cold square circulating fluidized beds (CFB). The pressure drop distribution along the riser and the saturation carrying capacity of gas for Geldart-B type particles were first analyzed. Under the condition of u0=4 m/s and Gs=21 kg/(m2 s), the back feeding particles were found to penetrate the lean gas-solid flow near the entrance (rear) wall before reaching the opposite (front) wall, thus leading to a relatively denser region near the front wall in the bottom bed. Higher solid circulation rate (u0=4 m/s, Gs=33 kg/(m2 s)) resulted in a higher particle concentration in the riser. However the back feeding particles with higher momentum increased the asymmetry of the particle concentration/velocity profile in the solid entrance region. Lower air velocity (u0=3.2 m/s) and Gs=21 kg/(m2 s), beyond the saturation carrying capacity of gas, induced an S-shaped axial solid distribution with a denser bottom zone. This limited the penetration of the back feeding particles and forced the fluidizing air to flow in the central region, thus leading to a higher solid holdup near the rear wall. Under the conditions of u0=4 m/s and Gs=21 kg/(m2 s), addition of coarse particles (dp=1145 m) into the bed made the radial distribution of solids more symmetrical. | Zhengyang Wang Shaozeng Sun Hao Chen Qigang Deng Guangbo Zhao Shaohua Wu | 2009 | Particuology2009，7，6： | 4 |
| 2 | Vapor deposition of aluminium oxide into N-rich mesoporous carbon framework as a reversible sulfur host for lithium-sulfur battery cathode显示文摘Restraining the shuttle effects of lithium polysulfides is the key to improve the cycling reversibility and stability of lithium-sulfur(Li-S)batteries for which design of robust sulfur hosts has been regarded as the most effective strategy.In this work,we report a new type of hybrid sulfur host which is composed of Al_(2)O_(3) homogenously decorated in nitrogen-rich mesoporous carbon framework(NMC-Al_(2)O_(3)).The NMC-Al_(2)O_(3) hybrid host features a poly-dispersed spherical morphology and a mesoporous configuration with high surface area and large pore volume that can accommodate a high sulfur content up to 73.5 wt.%.As a result,the fabricated NMC-Al_(2)O_(3)-S cathode exhibits all-round improvements in electrochemical properties in term of capacities(1,212 mAh·g^(-1)at 0.2 C;755 mAh·g^(-1)at 2 C),cycling charge-discharge reversibility(sustainably 100%efficiencies)and stability(1,000 cycles with only 0.023%capacity decay per cycle at 0.5 C).By contrast,the Al_(2)O_(3)-free NMC-S cathode shows both decreased capacities and rapidly descending Coulombic efficiencies during cycling.Density functional theory(DFH')calculations further reveal that the implanted Al_(2)O_(3) can greatly enhance the chemical adsorption and catalytic conversion for various lithium polysulfides and thereby effectively prevent the polysulfide shuttling and significantly improve the utilizability,reversibility and stability of sulfur cathode. | Fei Sun Zhibin Qu Hua Wang Xiaoyan Liu Tong Pei Rui Han Jihui Gao Guangbo Zhao Yunfeng Lu | 2021 | Nano Research2021，14，1： | 3 |
| 3 | Arenobufagin is a novel isoform-specific probe for sensing human sulfotransferase 2A1显示文摘Human cytosolic sulfotransferase 2 A1(SULT2A1) is an important phase II metabolic enzyme. The detection of SULT2A1 is helpful for the functional characterization of SULT2A1 and diagnosis of its related diseases. However, due to the overlapping substrate specificity among members of the sulfotransferase family, it is difficult to develop a probe substrate for selective detection of SULT2A1. In the present study, through characterization of the sulfation of series of bufadienolides, arenobufagin(AB) was proved as a potential probe substrate for SULT2A1 with high sensitivity and specificity. Subsequently, the sulfation of AB was characterized by experimental and molecular docking studies. The sulfate-conjugated metabolite was identified as AB-3-sulfate.The sulfation of AB displayed a high selectivity for SULT2A1 which was confirmed by in vitro reaction phenotyping assays. The sulfation of AB by human liver cytosols and recombinant SULT2A1 both obeyed Michaelis-Menten kinetics, with similar kinetic parameters. Molecular docking was performed to understand the interaction between AB and SULT2A1, in which the lack of interaction with Met-137 and Tyr-238 of SULT2A1 made it possible to eliminate substrate inhibition of AB sulfation. Finally, the probe was successfully used to determine the activity of SULT2A1 and its isoenzymes in tissue preparations of human and laboratory animals. | Xiangge Tian Chao Wang Peipei Dong Yue An Xinyu Zhao Weiru Jiang Gang Wang Jie Hou Lei Feng Yan Wang Guangbo Ge Xiaokui Huo Jing Ning Xiaochi Ma | 2018 | Acta Pharmaceutica Sinica B2018，8，5： | 2 |
| 4 | Effect of air preheating and fuel moisture on combustion characteristics of corn straw in a fixed bed 显示文摘 | Zhao Wei Li Zhengqi Zhao Guangbo | 2008 | Energy Conversion and Management2008，49，12： | 1 |
| 5 | Effect of corn stalk length on combustion characteristics in a fixed bed显示文摘 | Li Zhengqi Zhao Wei Zhao Guangbo | 2008 | Energy & Fuels2008，22，： | 1 |
| 6 | Numerical simulations of combustion characteristics and NOxx emissions for two configurations of swirl coal burners in a 300 MW wall-fired boiler 显示文摘 | Li Zhengqi Zeng Lingyan Zhao Guangbo | 2011 | Heat Transfer2011，60，5： | 1 |
| 7 | Milling Parameters Optimization of Al-Li Alloy Thin-Wall Workpieces Using Response Surface Methodology and Particle Swarm Optimization显示文摘To improve the milling surface quality of the Al-Li alloy thin-wall workpieces and reduce the cutting energy consumption.Experimental research on the milling processing of AA2195 Al-Li alloy thin-wall workpieces based on Response Surface Methodology was carried out.The single factor and interaction of milling parameters on surface roughness and specific cutting energy were analyzed,and the multi-objective optimization model was constructed.The Multiobjective Particle Swarm Optimization algorithm introducing the Chaos Local Search algorithm and the adaptive inertial weight was applied to determine the optimal combination of milling parameters.It was observed that surface roughness was mainly influenced by feed per tooth,and specific cutting energy was negatively correlated with feed per tooth,radial cutting depth and axial cutting depth,while cutting speed has a non-significant influence on specific cutting energy.The optimal combination of milling parameters with different priorities was obtained.The experimental results showed that the maximum relative error of measured and predicted values was 8.05%,and the model had high reliability,which ensured the low surface roughness and cutting energy consumption.It was of great guiding significance for the success of Al-Li alloy thin-wall milling with a high precision and energy efficiency. | Haitao Yue Chenguang Guo Qiang Li Lijuan Zhao Guangbo Hao | 2020 | Computer Modeling in Engineering & Sciences2020，，9： | 1 |
| 8 | A novel TICT-based near-infrared fluorescent probe for light-up sensing and imaging of human serum albumin in real samples显示文摘Human serum albumin(HSA) has emerged as a pivotal biomarker and prognostic indicator for various human diseases. Real-time sensing and visual tracking of HSA in plasma or other biological systems will immensely facilitate the basic researchers and clinicians to better understand HSA-associated biological processes. Herein, a novel near-infrared(NIR) fluorescent probe(7-HTCF) was rationally constructed for light-up sensing and in-situ imaging of HSA in real samples, based on the principle of twisted intramolecular charge transfer(TICT). Under physiological conditions, 7-HTCF could be efficiently trapped by HSA to form a stable complex via binding on a non-drug binding site, while the complex emitted strong fluoresce signals around 670 nm. Further investigations demonstrated that 7-HTCF displayed a great combination of excellent selectivity and good chemical stability, as well as rapid fluorescent response and ultra-high sensitivity for HSA detection. Particularly, the newly developed light-up probe has been successfully utilized for quantitative detection of HSA in diluted plasma samples, while its readouts are hardly affected by the addition of therapeutic agents and herbal medicines. 7-HTCF is also successfully used for in-situ imaging of the reabsorbed HSA in living renal cells, while this dye exhibits good cell permeability and high resolution for in-situ imaging in living cells. Collectively, a novel TICT-based near-infrared fluorescent probe was devised for highly selective and ultra-sensitive sensing of HSA in plasma samples or imaging HSA in living cells, which offered a practical tool for clinical tests and for exploring HSA-associated biological processes. | Yufan Fan Fangyuan Wang Fanbin Hou Lai Wei Guanghao Zhu Dongfang Zhao Qing Hu Tao Lei Ling Yang Ping Wang Guangbo Ge | 2023 | Chinese Chemical Letters2023，34，2： | 0 |
| 9 | The hidden risk of microplastic-associated pathogens in aquatic environments显示文摘Increasing studies of plastisphere have raised public concern about microplastics(MPs)as vectors for pathogens,especially in aquatic environments.However,the extent to which pathogens affect human health through MPs remains unclear,as controversies persist regarding the distinct pathogen colonization on MPs as well as the transmission routes and infection probability of MP-associated pathogens from water to humans.In this review,we critically discuss whether and how pathogens approach humans via MPs,shedding light on the potential health risks involved.Drawing on cutting-edge multidisciplinary research,we show that some MPs may facilitate the growth and long-range transmission of specific pathogens in aquatic environments,ultimately increasing the risk of infection in humans.We identify MP-and pathogen-rich settings,such as wastewater treatment plants,aquaculture farms,and swimming pools,as possible sites for human exposure to MP-associated pathogens.This review emphasizes the need for further research and targeted interventions to better understand and mitigate the potential health risks associated with MP-mediated pathogen transmission. | Huan Zhong Mengjie Wu Christian Sonne Su Shiung Lam Raymond W.M.Kwong Yuelu Jiang Xiaoli Zhao Xuemei Sun Xuxiang Zhang Chengjun Li Yuanyuan Li Guangbo Qu Feng Jiang Huahong Shi Rong Ji Hongqiang Ren | 2023 | Eco-Environment & Health2023，2，3： | 0 |
| 10 | Possible role of extracellular vesicles in exogenous chemical exposure-associated health concern显示文摘Extracellular vesicles(EVs) are mediators of intercellular message communication by transferring lipids, proteins, genetic materials, and are therefore involved in a wide spectrum of physiological or pathological processes. Exogenous chemicals exposure may affect the function of EVs at the biogenesis, secretion, transport or reception stage, which could further result in abnormal information communication between cells, and thus induce toxicity and diseases. This review briefly explores the role of EVs in chemical exposure-associated health concern and progressive diseases. | Guangbo Qu Xingchen Zhao Yanna Liu Fang Hao Jie Gao Lili Yang Qunfang Zhou Guibin Jiang | 2019 | Journal of Environmental Sciences2019，31，6： | 0 |
| 11 | 基于生物分子检测的纳米孔制备研究显示文摘Many emerging applications of nanopore detection such as proteins,RNA and DNA has been reported,in which the size and structure of the biomolecules is detected by the block current when they transport through a single nanopore[1].The smaller the size of the nanopore is,the higher detection accuracy will be obtained.Nanochannel fabrication using the latent track of high LET heavy ions in solids has the advantage of precise pore geometry control and pore production.Compared with solid nanopore fabrication by drilling in silicon nitride membrane,polymeric nanopore using ion track etching technique can reduce both the material and fabrication cost. | Zhao Jing Du Guanghua Li Yaning Guo Jinlong Mao Guangbo | 2018 | IMP & HIRFL Annual Report2018，，1： | 0 |
| 12 | 快采样测锥形纳米孔I-V曲线显示文摘After single heavy ion irradiation and asymmetric chemical etching,the single conical nanopore(based on PET membrane)can be successfully fabrication[1].The I-V hysteresis curve of conical nanopore measured in low concentration magnesium chloride solution is similar to the I-V curve of memristor[2].To further study this phenomenon,we test the nanochannel by fast sampling measurement.With the data acquisition card(USB-6003,National Instruments)and picoammeter(6482,Keithley),we can build a fast sampling and acquisition system,which can obtain 20000 data points per second at the analog output of the 6482 picoammeter.This is 2000 times that of the slow digital sampling method provided by 6482 picoammeter(10 data points per second),and it is able to observe the fast change and details of the ionic current through the nanopore. | Li Yaning Du Guanghua Guo Jinlong Zhao Jing Mao Guangbo | 2018 | IMP & HIRFL Annual Report2018，，1： | 0 |
| 13 | 固液界面的离子束分析显示文摘Investigations of the microstructure formation and elemental formation at the solid-liquid interfaces are of great significance due to the various valuable applications such as super-capacitors,battery,medical implantation and electrochemical industry and research.Traditional ion beam analysis is performed in vacuum which just allows investigation of solid samples.Liquids interface with a solid surface are not accessible for the vacuum measurements in the ion beam laboratory.By utilizing a silicon nitride vacuum window coated with 10 nm aluminum we built up an enclosed chamber,which can hold solution in vacuum and is able to perform precise elemental analysis by means of ion beam analysis at the solid-liquid interface.By utilizing a silicon nitride vacuum window coated with several nm aluminum we built up an enclosed chamber,which can hold solution in vacuum and is able to perform precise elemental analysis by means of ion beam analysis at the solid-liquid interface the chamber of the solid-liquid interface probe used the aluminum layer as electrode,which allowed online apply and adjust the electric field at the interface. | Li Xiaoyue Du Guanghua Yu Tao Zhang Hailei Shen Hao Guo Jinlong Wu Ruqun Liu Wenjing Li Yaning Zhao Jing Mao Guangbo Shen Cheng | 2018 | IMP & HIRFL Annual Report2018，，1： | 0 |
| 14 | Simultaneous utilization of electro-generated O_(2)and H_(2)for H_(2)O_(2)production:An upgrade of the Pd-catalytic electro-Fenton process for pollutants degradation显示文摘The Electro-Fenton(EF)process is one of the promising advanced oxidation processes(AOPs)for environmental remediation.The H_(2)O_(2) yield of EF process largely determines its performance on organic pollutants degradation.Conventional Pd-catalytic EF process generates H_(2)O_(2) via the combination reaction of anodic O_(2) and cathodic H;.However,the relatively expensive catalyst limits its application.Herein,a hybrid Pd/activated carbon(Pd/AC)-stainless steel mesh(SS)cathode(PACSS)was proposed,which enables more efficie nt H_(2)O_(2)generation.It utilizes AC,the support of Pd catalyst,as part of cathode for H_(2)O_(2) generation via 2-electron anodic O_(2) reduction,and SS serve as a current distributor.Moreover,H_(2)O_(2) could be catalytically decomposed upon AC to generate highly reactive·OH,which avoids the use of Fe;.Compared with conventional Pd catalyst,H_(2)O_(2) concentration obtained by PACSS cathode is248.2%higher,the O_(2)utilization efficiency was also increased from 3.2%to 10.8%.Within 50 min,26.3%,72.5%,and 94.0%H_(2)O_(2) was decomposed by Pd,AC,and Pd/AC.Fluorescence detection results implied that Pd/AC is effective upon H_(2)O_(2) activation for·OH generation.Finally,iron-free EF process enabled by PACSS cathode was examined to be effective for reactive blue 19(RB19)degradation.After continuous running for 10 cycles(500 min),the PACSS cathode was still stable for H_(2)O_(2)generation,H_(2)O_(2)activation,and RB19 degradation,showing its potential application for organic pollutants degradation without increase in the running cost. | Wei Zhou Xiaoxiao Meng Liang Xie Junfeng Li Yani Ding Yanlin Su Jihui Gao Guangbo Zhao | 2022 | Chinese Journal of Chemical Engineering2022，35，4： | 0 |
| 15 | Method of DNA Labeling in Fixed Cells for STORM Microscopy of Nuclear Chromatin显示文摘Genomic DNA in eukaryotic cells is packaged into chromatin composed of DNA,histones,and associated proteins.Nuclear chromatin plays a very important role in the storage and transmission of genetic information.In order to obtain nanoscale chromatin organization with super-resolution microscopy. | Wu Ruqun Du Guanghua Guo Jinlong Liu Wenjing Li Yaning Zhao Jing Mao Guangbo Shen Cheng | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 16 | Magnetically Gated PET Nanochannel显示文摘Ion channels with gating function exist in nature widely.The ion channels in the organism make corresponding response when there are specific external stimuli.Many researchers hope to use a variety of artificial nanochannels to imitate the ion channels in the organism to fabricate intelligent gating nanochannels[1,2]. | Li Yaning Du Guanghua Zhao Jing Guo Jinlong Wu Ruqun Liu Wenjing Mao Guangbo Shen Cheng | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 17 | Reverse Study of a Commercial SRAM with Areal Time SEU Analysis System显示文摘Reverse engineering has a significant infuence on the dissemination of technology in the electronics industry1.Single Event Upset(SEU)is one of the most common injection faults induced by energetic ions in integrated circuits(ICs),and it's attractive to utilize SEU as a reverse method because SEU is seriously affcted by the design layout of ICs. | Guo Jinlong Mao Guangbo Liu Wenjing Wu Ruqun Li Yaning Zhao Jing Shen Cheng Du Guanghua | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 18 | Localization Precision of Single Heavy-Ion Scintillation Imaging System显示文摘Single event effect(SEE)is the most important radiation effect.About 50 percent of spacecraft failures are due to SEE induced by space radiation.Nowadays,with the rapid reduction of the feature size of integrated circuits become more and more sensitive to SEE. | Mao Guangbo Guo Jinlong Wu Ruqun Liu Wenjing Li Yaning Zhao Jing Shen Cheng Du Guanghua | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 19 | A pplication of Track-etched Nanopore in Biomolecules Detection显示文摘Gene therapy has come closer to reality with the improvements of sequencing technology,and a low cost and rapid method is required to sequence personal genomes with high throughput. | Zhao Jing Du Guanghua Li Yaning Guo Jinlong Mao Guangbo Liu Wenjing Wu Ruqun Shen Cheng | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 20 | A Small Angle Irradiation System for Study of the Chromatin Dynamics along the Ion Trajectory显示文摘The eukaryotic genome is organized within cells as chromatin,which is constantly threatened by genotoxic factors including ionizing radiation,and then resulting in the formation of various DNA lesions. | Shen Cheng Du Guanghua Wu Ruqun Liu Wenjing Guo Jinlong Li Yaning Zhao Jing Mao Guangbo | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
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