|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | m^6A-dependent biogenesis of circular RNAs in male germ cells显示文摘The majority of circular RNAs(circRNAs)spliced from coding genes contain open reading frames(ORFs)and thus,have protein coding potential.However,it remains unknown what regulates the biogenesis of these ORF-containing circRNAs,whether they are actually translated into proteins and what functions they play in specific physiological contexts.Here,we report that a large number of circRNAs are synthesized with increasing abundance when late pachytene spermatocytes develop into round and then elongating spermatids during murine spermatogenesis.For a subset of circRNAs,the back splicing appears to occur mostly at m^6A-enriched sites,which are usually located around the start and stop codons in linear mRNAs.Consequently,approximately a half of these male germ cell circRNAs contain large ORFs with m^6A-modified start codons in their junctions,features that have been recently shown to be associated with protein-coding potential.Hundreds of peptides encoded by the junction sequences of these circRNAs were detected using liquid chromatography coupled with mass spectrometry,suggesting that these circRNAs can indeed be translated into proteins in both developing(spermatocytes and spermatids)and mature(spermatozoa)male germ cells.The present study discovered not only a novel role of m^6A in the biogenesis of coding circRNAs,but also a potential mechanism to ensure stable and long-lasting protein production in the absence of linear mRNAs,i.e.,through production of circRNAs containing large ORFs and m^6A-modified start codons in junction sequences. | Chong Tang Yeming Xie Tian Yu Na Liu Zhuqing Wang Rebekah J.Woolsey Yunge Tang Xinzong Zhang Weibing Qin Ying Zhang Ge Song Weiwei Zheng Juan Wang Weitian Chen Xiongyi Wei Zhe Xie Rachel Klukovich Huili Zheng David R.Quilici Wei Yan | 2020 | Cell Research2020，30，3： | 12 |
| 2 | The mitochondrial genome encodes abundant small noncoding RNAs显示文摘识别的小 noncoding RNA 都被原子染色体远因此编码。这里,我们主要报导鼠科、人的 mitochondrial 染色体编码几千小 noncoding RNA,它是源于 mitochondrial 基因(主人基因) 的感觉抄本,并且我们称为这些小 RNA mitochondrial 编码染色体的小 RNA (mitosRNAs ) 。影响的 DICER inactivation,但是完全没废除 mitosRNA 生产。MitosRNAs 看起来是当前未辩别出的 mitochondrial ribonucleases 的产品。提高的表示在 vitro 他们的主人基因铺平的 mitosRNAs 的 Overexpression,和 dysregulated mitosRNA 表示通常在 vivo 与异常 mitochondrial 基因表示被联系。我们的数据证明除了 37 已知的 mitochondrial 基因,哺乳动物的 mitochondrial 染色体也编码丰富的 mitosRNAs,它可以在房间在 mitochondrial 基因表示的控制起一个重要规章的作用。 | Seungil Ro Hsiu-Yen Ma Chanjae Park Nicole Ortogero Rui Song Grant W Hennig Huili Zheng Yung-Ming Lin2 Loredana Moro Jer-Tsong Hsieh wei Yant | 2013 | Cell Research2013，23，6： | 3 |
| 3 | Enantioseletive bioaccumulation of tebuconazole in earthworm Eisenia fetida显示文摘Methods of extraction and determination of tebuconazole enantiomers in earthworm(Eisenia fetida)were developed by capillary electrophoresis(CE)and high performance liquid chromatography(HPLC).Both CE and HPLC have excellent resolution and recovery.The linearity ranges were 2.9-102.4mg/kg and 3.0-99.6mg/kg for(+)-R-tebuconazole and(-)-S-tebuconazole respectively in CE,and from 0.56 to 1000mg/kg for both enantiomers in HPLC.Enantioselective bioaccumulation in earthworms from soil was investigated under laboratory condition at concentrations of 10 and 50 mg/kg dw in soil.The uptake kinetics of(+)-R-tebuconazole fitted the firstorder kinetics well with r2 0.97 and 0.94 under 10 and 50mg/kg dw exposure condition,respectively,while(-)-S-tebuconazole with r 2 0.75 and 0.22 did not show the same.Bioaccumulation of tebuconazole in earthworm tissues was enantioselective with a preferential accumulation of(+)-R-tebuconazole.The(+)-R-tebuconazole might also have biomagnifying effect potential in earthworm food chain with biota-sediment accumulation factor(BSAF) of 1.64kg OC/kg lip in 10 mg/kg dw exposure group and 2.61kg OC/kg lip in 50mg/kg dw exposure group from soil to earthworm after 36 days.Although(-)-S-tebuconazole shares the same physicochemical properties with(+)-R-tebuconazole,it did not biomagnify.BSAFs of(-)-S-tebuconazole were 0.50kg OC/kg lip(10 mg/kg dw tebuconazole exposure) and 0.28kg OC/kg lip(50mg/kg dw tebuconazole exposure) after 36 days,which was possibly owing to biotransformation or metabolism in earthworm tissues. | Dingyi Yu Jianzhong Li Yanfeng Zhang Huili Wang Baoyuan Guo Lin Zheng | 2012 | Journal of Environmental Sciences2012，24，12： | 2 |
| 4 | A compact frequency-reconfigurable patch antenna for Beidou(COMPASS)navigation system显示文摘 | Sun Chao Zheng Huili Zhang Lingfei | 2014 | IEEE Antennas and Wireless Propagation Letters2014，13，5： | 1 |
| 5 | Research on Telecommunication Resale Service Supply Chain Coordination with Revenue Sharing Contract显示文摘 | ZHENG Huili DA Qingli CAO Aihong | 2004 | Journal of Southeast University2004，20，1： | 1 |
| 6 | Modelling and Simulation of PDE Problems in Modelica显示文摘 | Li Zhihua Zheng Ling Zhang Huili | 2009 | Inter- national Journal of Materials and Structural Integri ty2009，3，4： | 1 |
| 7 | Song Shunxian,Study on Dual-Frequency Planar Monopole Antennas显示文摘 | Zheng Huili Tang Mingxiang | 2005 | IEEE International Symposium on Microwave Antenna Propagation and EMC Technologies for Wireless Communications Proceedings2005，2005，： | 1 |
| 8 | Evidence for the Natural Toxins from the Mushroom Trogia venenata as a Cause of Sudden Unexpected Death in Yunnan Province, China显示文摘 | Zhong‐YuZhou Guo‐QingShi RobertFontaine KunWei TaoFeng FangWang Gang‐QiangWang YanQu Zheng‐HuiLi Ze‐JunDong Hua‐JieZhu Zhu‐LiangYang GuangZeng Ji‐KaiLiu | 2012 | Angew Chem Int Ed2012，，10： | 1 |
| 9 | Research on telecommunication resale service supply chain coordination with revenue-sharing contract显示文摘 | Da Qingli | 2004 | Journal of Southeast University2004，20，1： | 1 |
| 10 | Evidence for the Natural Toxins from the Mushroom Trogia venenata as a Cause of Sudden Unexpected Death in Yunnan Province, China显示文摘 | Zhong‐YuZhou Guo‐QingShi RobertFontaine KunWei TaoFeng FangWang Gang‐QiangWang YanQu Zheng‐HuiLi Ze‐JunDong Hua‐JieZhu Zhu‐LiangYang GuangZeng Ji‐KaiLiu | 2012 | Angew Chem Int Ed2012，，10： | 1 |
| 11 | Research on telecommunication resale service supply chain coordination with revenue-sharing contract显示文摘 | Zheng Huili Da Qingli | 2004 | Journal of Southeast University2004，20，1： | 1 |
| 12 | Efficacy and safety of probiotics as adjuvant agents for Helicobacterpylori infection: A meta?analysis显示文摘 | Zhifa Lv Ben Wang Xiaojiang Zhou Fucai Wang Yong Xie Huilie Zheng Nonghua Lv | 2015 | Experimental and Therapeutic Medicine2015，，3： | 1 |
| 13 | Interleukin 1 receptor antagonist reduces lethality and intestinal toxicity of 5-Fluorouracil in a mouse mucositis model显示文摘 | Zhenqian Wu Xiaodong Han Shenyin Qin Qi Zheng Zhigang Wang Di Xiang Jing Zhang Huili Lu Mingyuan Wu Shunying Zhu Yan Yu Yu Wang Wei Han | 2011 | Biomedicine & Pharmacotherapy2011，，5： | 1 |
| 14 | Research on telecommunication resale service supply chain coordination with revenue sharing contract显示文摘 | ZHENG Huili DA Qingli CAO Aihong | 2004 | Journal of Southeast University2004，20，1： | 1 |
| 15 | Fearful Encounters: Demons, Magic Weapons, and Fierce Warriors in Xiyangji显示文摘自从它的建立,明王朝被边阶问题和外国威胁麻烦。这种状况与日本海盗行为危机,从东北的满族威胁,在州用先进武器武装的欧洲水手,和特别 Toyotomi Hideyoshis (153798 ) 朝鲜语在第 16 个世纪变得更坏远征,它严重地质问了中国的宗主权。当明帝国权威被察觉国内外在衰落上时,在第 16 个世纪的最后年里写, Xiyang ji 作为它的主要题目的担心拿中外的关系。这篇论文检验外国其它怎么在 Xiyang ji 被想象。尽管 Xiyang ji 试图肯定 Sinocentric 世界的古老的神话,由使成为魔鬼订外国其它并且在中国顺序以内包含外面的世界,它也在外国文化和文化相关性的了解表明真兴趣。通过介绍中国舰队在外国陆地经验丰富的可怕的相遇,最重要地, Xiyang ji 加亮在 Sinocentric 世界顺序的旧神话之间的怒视的差距,外国其它由此被看作献礼题目,和新现实,在哪个外国作为独立实体为他们的地位猛烈地战斗。我说服那,在使用战争到重新想象中外的关系, Xiyang ji 引起注意到外国威胁,旧知识系统的限制,和进一步了解外面的世界的紧急,因此表明中国学者逐渐地停止了作为世界的中心识别中国的一个过程的开始。 | Huili ZHENG | 2014 | Frontiers of Literary Studies in China-Selected Publications from Chinese Universities2014，8，3： | 0 |
| 16 | Author Correction: The mitochondrial genome encodesabundant small noncoding RNAs显示文摘It has been brought to our attention that our paper1 published in Cell Research in 2013 contains duplicated panels in Fig.3A(HX1_30-51 and mmu-let-7d).By examining the lab records,we found that the gel image of H-X1_30-51 appeared to be used as a place holder for mmu-let-7d(the loading control)when the original figure was first assembled.Unfortunately,it was never replaced by the real mmu-let-7d gel image.We repeated the PCR assays and added the mmu-let-7d gel image to the corrected Fig.3A.This correction does not affect the major findings and conclusions of this work.We apologize for this oversight. | Seungil Ro Hsiu-Yen Ma Chanjae Park Nicole Ortogero Rui Song Grant W.Hennig Huili Zheng Yung-Ming Lin Loredana Moro Jer-Tsong Hsieh Wei Yan | 2021 | Cell Research2021，31，12： | 0 |
| 17 | The SARS-CoV-2 main protease induces neurotoxic TDP-43 cleavage and aggregates显示文摘Dear Editor,Neurologic manifestations associated with many COVID-19 patients,including acute infection with severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)and long COVID,have been proven by increasing evidence.1 To date,most studies have focused on how SARS-CoV-2 invades the nervous system and the consequent neuropathological changes.2,3 In contrast,the specific mechanism by which SARS-CoV-2 infection leads to neurological disease remains unclear. | Jiaxin Yang Yan Li Shijin Wang Huili Li Lili Zhang Haichen Zhang Pei-Hui Wang Xiangyu Zheng Xiao-Fang Yu Wei Wei | 2023 | Signal Transduction and Targeted Therapy2023，8，4： | 0 |
| 18 | Spatiotemporal Prediction of Urban Traffics Based on Deep GNN显示文摘Traffic prediction already plays a significant role in applications like traffic planning and urban management,but it is still difficult to capture the highly non-linear and complicated spatiotemporal correlations of traffic data.As well as to fulfil both long-termand short-termprediction objectives,a better representation of the temporal dependency and global spatial correlation of traffic data is needed.In order to do this,the Spatiotemporal Graph Neural Network(S-GNN)is proposed in this research as amethod for traffic prediction.The S-GNN simultaneously accepts various traffic data as inputs and investigates the non-linear correlations between the variables.In terms of modelling,the road network is initially represented as a spatiotemporal directed graph,with the features of the samples at the time step being captured by a convolution module.In order to assign varying attention weights to various adjacent area nodes of the target node,the adjacent areas information of nodes in the road network is then aggregated using a graph network.The data is output using a fully connected layer at the end.The findings show that S-GNN can improve short-and long-term traffic prediction accuracy to a greater extent;in comparison to the control model,the RMSE of S-GNN is reduced by about 0.571 to 9.288 and the MAE(Mean Absolute Error)by about 0.314 to 7.678.The experimental results on two real datasets,Pe MSD7(M)and PEMS-BAY,also support this claim. | Ming Luo Huili Dou Ning Zheng | 2024 | Computers, Materials & Continua2024，78，1： | 0 |
| 19 | Interfacial properties of 2D WS_(2)on SiO_(2)substrate from X-ray photoelectron spectroscopy and firstprinciples calculations显示文摘Two-dimensional(2D)WS_(2)films were deposited on SiO_(2)wafers,and the related interfacial properties were investigated by high-resolution X-ray photoelectron spectroscopy(XPS)and first-principles calculations.Using the direct(indirect)method,the valence band offset(VBO)at monolayer WS_(2)/SiO_(2)interface was found to be 3.97 eV(3.86 eV),and the conduction band offset(CBO)was 2.70 eV(2.81 eV).Furthermore,the VBO(CBO)at bulk WS_(2)/SiO_(2)interface is found to be about 0.48 eV(0.33 eV)larger due to the interlayer orbital coupling and splitting of valence and conduction band edges.Therefore,the WS_(2)/SiO_(2)heterostructure has a Type I energy-band alignment.The band offsets obtained experimentally and theoretically are consistent except the narrower theoretical bandgap of SiO_(2).The theoretical calculations further reveal a binding energy of 75 meV per S atom and the totally separated partial density of states,indicating a weak interaction and negligible Fermi level pinning effect between WS_(2)monolayer and SiO_(2)surface.Our combined experimental and theoretical results provide proof of the sufficient VBOs and CBOs and weak interaction in 2D WS_(2)/SiO_(2)heterostructures. | Changjie Zhou Huili Zhu Weifeng Yang Qiubao Lin Tongchang Zheng Lan Yang Shuqiong Lan | 2022 | Frontiers of physics2022，17，5： | 0 |
| 20 | Energy band alignment of 2D/3D MoS_(2)/4H-SiC heterostructure modulated by multiple interfacial interactions显示文摘The interfacial properties of MoS_(2)/4H-SiC heterostructures were studied by combining first-principles calculations and X-ray photoelectron spectroscopy.Experimental(theoretical)valence band offsets(VBOs)increase from 1.49(1.46)to 2.19(2.36)eV with increasing MoS_(2) monolayer(1L)up to 4 layers(4L).A strong interlayer interaction was revealed at 1L MoS_(2)/SiC interface.Fermi level pinning and totally surface passivation were realized for 4H-SiC(0001)surface.About 0.96e per unit cell transferring forms an electric field from SiC to MoS_(2).Then,1L MoS_(2)/SiC interface exhibits type I band alignment with the asymmetric conduction band offset(CBO)and VBO.For 2L and 4L MoS_(2)/SiC,Fermi level was just pinning at the lower MoS_(2)1L.The interaction keeps weak vdW interaction between upper and lower MoS_(2) layers.They exhibit the type II band alignments and the enlarged CBOs and VBOs,which is attributed to weak vdW interaction and strong interlayer orbital coupling in the multilayer MoS_(2).High efficiency of charge separation will emerge due to the asymmetric band alignment and built-in electric field for all the MoS_(2)/SiC interfaces.The multiple interfacial interactions provide a new modulated perspective for the next-generation electronics and optoelectronics based on the 2D/3D semiconductors heterojunctions. | Huili Zhu Zifan Hong Changjie Zhou Qihui Wu Tongchang Zheng Lan Yang Shuqiong Lan Weifeng Yang | 2023 | Frontiers of physics2023，18，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员