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| 1 | Individualized Design of the Ventilator Mask based on the Residual Concentration of CO2显示文摘OSAHS(Obstructive Sleep Apnea Hypopnea Syndrome)is a respiratory disease mainly characterized by limited and repeated pauses of breathing in sleep.Currently,the optimal treatment is to apply CPAP(Continuous Positive Airway Pressure)ventilation on the upper airway of the patient through a household respiratory machine.However,if the ventilator mask is designed improperly,it might cause the residue and repeated inhalation of CO2,which will exert an adverse impact on the therapeutic effect.Present research numerically analyzed the CO2 transportation inside a commercial ventilator mask(Mirage SoftGel,ResMed,Australia)based on the reconstructed 3D numerical model of a volunteer's face and performed the improved design of the ventilator mask in terms of the CO2 residual concentration below the nostrils.The fluid dynamic analyses showed that at the end time of expiratory,the CO2 residual concentration below the nostrils is close to 4%.To improve the therapeutic effect,we changed the position of the exhaust holes and found that by moving the exhaust holes to the bottom of the ventilator mask,the CO2 residual concentration below the nostrils would be reduced to no more than 1%.This study established a near physiological computational model and provided a new method for the individualized design of the commercial ventilator mask. | Zhiguo Zhang Zhenxiao Li Yifei Zhang Zhenze Wang Minzhou Luo | 2018 | Computer Modeling in Engineering & Sciences2018，，11： | 3 |
| 2 | Enhanced learning and memory in GAT1 heterozygous mice显示文摘-Aminobutyric 酸(伽马氨基丁酸) 是在中央神经系统的主要禁止的 neurotransmitter。伽马氨基丁酸传播的结束通过膜蛋白质的一个家庭的行动,叫的伽马氨基丁酸 transporters (GAT14 ) 。伽马氨基丁酸系统涉及存储器的调整,这很好被建立。我们的以前的学习显示出老鼠展出了损害马头鱼尾的怪兽依赖者学习和记忆的那同型结合的 GAT1/ 。在鼠标上评估内长的减少的伽马氨基丁酸举起的影响认知行为,学习和异质接合的 GAT1+/ 鼠标的存储器的能力被被动回避范例和莫利斯舞水迷宫检测。洞板范例也被用来在如此的老鼠在焦虑相关的行为或探索行为测量变化。作为 synaptic 粘性的一种形式,长期的 potentiation 在老鼠被记录海马趾的 CA1 区域。我们发现了显示的老鼠增加了的那 GAT1+/ 学习并且记忆,减少的像焦虑的行为,和与野类型、同型结合的 GAT1/ 老鼠相比的最高的 synaptic 粘性。我们的结果建议在 GAT1 活动的中等减小引起在鼠标学习和记忆的改进。 | Jun Shi Youqing Cai Guoxiang Liu Neng Gong Zhenze Liu Tianle Xu Zhugang Wang Jian Fei | 2012 | Acta Biochimica et Biophysica Sinica2012，44，4： | 3 |
| 3 | Identification and characterization of BoPUB3: a novel interaction protein with S-locus receptor kinase in Brassica oleracea L.显示文摘Armadillo repeat containing 1 (ARC1) is phosphorylated by S-locus receptor kinase (SRK) and functions as a positive regulator in self-incompatibility response of Brassica. However, ARC1 only causes partial breakdown of the self-incompatibility response, and other SRK downstream factors may also participate in the self-incompatibility signaling pathway. In the present study, to search for SRK downstream targets, a plant U-box protein 3 (BoPUB3) was identified from the stigma of Brassica oleracea L. BoPUB3 was highly expressed in the stigma, and its expression was increased with the stigma development and reached to the highest level in the mature-stage stigma. BoPUB3, a 76.8-kDa protein with 697 amino acids, is a member of the PUB-ARM family and contains three domain characteristics of BoARC1, including a U-box N-terminal domain, a U-box motif, and a C-terminal arm repeat domain. The phylogenic tree showed that BoPUB3 was close to BoARC1. The synteny analysis revealed that B. oleracea chromosomal region containing BoPUB3 had high synteny with the Arabidopsis thaliana chromosomal region containing AtPUB3 (At3G54790). In addition, the subcellular localization analysis showed that BoPUB3 primarily localized in the plasma membrane and also in the cytoplasm. The combination of the yeast two-hybrid and in vitro binding assay showed that both BoPUB3 and BoARC1 could interact with SRK kinase domain, and SRK showed much higher level of β-galactosidase activity in its interaction with BoPUB3 than with BoARC1. These results implied that BoPUB3 is a novel interactor with SRK, which lays a basis for further research on whether PUB3 participates in the self-incompatibility signaling pathway. | Songmei Shi Qiguo Gao Tonghong Zuo Zhenze Lei Quanming Pu Yukui Wang Guixi Liu Xinhua He Xuesong Ren Liquan Zhu | 2019 | Acta Biochimica et Biophysica Sinica2019，51，7： | 2 |
| 4 | Adsorption behavior and mechanism of Cd(II) on loess soil from China显示文摘 | Yan Wang Xiaowu Tang Yunmin Chen Liangtong Zhan Zhenze Li Qiang Tang | 2009 | Journal of Hazardous Materials2009，，1： | 1 |
| 5 | Molecular characterization of the celiac disease epitope domains in α-gliadin genes in Aegilops tauschii and hexaploid wheats (Triticum aestivum L.)显示文摘 | Zhenze Xie Congyan Wang Ke Wang Shunli Wang Xiaohui Li Zhao Zhang Wujun Ma Yueming Yan | 2010 | Theoretical and Applied Genetics2010，，7： | 1 |
| 6 | Spatial light modulation for femtosecond laser manufacturing:Current developments and challenges显示文摘Since the invention of lasers,spatial-light-modulated laser processing has become a powerful tool for various applications.It enables multidimensional and dynamic modulation of the laser beam,which significantly improves the processing efficiency,accuracy,and flexibility,and presents wider prospects over traditional mechanical technologies for machining three-dimensional,hard,brittle,or transparent materials.In this review,we introduce:(1)The role of spatial light modulation technology in the development of femtosecond laser manufacturing;(2)the structured light generated by spatial light modulation and its generation methods;and(3)representative applications of spatial-light-modulated femtosecond laser manufacturing,including aberration correction,parallel processing,focal field engineering,and polarization control.Finally,we summarize the present challenges in the field and possible future research. | ZANG Xue LIU ZiTing XU YiShi WANG Yi WANG Qing LI ZhenZe WANG Lei | 2024 | Science China(Technological Sciences)2024，67，1： | 0 |
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