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20篇 您的检索式:作者名="Zhernakova"
    题名 作者 年代 出处 被引量
1Pharmacomicrobiomics: a novel route towards personalized medicine?显示文摘在药反应的内部个人的异质是影响病人幸福并且在社会水平上提出庞大的临床、金融的负担的一个严重问题。Pharmacogenomics 在关于药反应可变性或药毒性的对单个基因背景的影响的研究的最前线,并且最近,内脏 microbiome,也被称为第二个染色体,在这个方面作为一个重要播放器被认出了。而且, microbiome 是为由于机会改进药功效和安全操作它的作文的一个很吸引人的目标。Pharmacomicrobiomics 是调查 microbiome 变化和药反应和布置(吸收,分发,新陈代谢和排泄) 的相互影响的一个新兴的领域。在这评论,我们提供历史的概述并且在在内脏 microbiome,主人和药之间的复杂相互作用上检验当前的最先进的知识。我们主张那联合 pharmacogenomics 和 pharmacomicrobiomics 将为在个性化的药做主要进展提供一个重要基础。Marwah Doestzada Arnau Vich Vila Alexandra Zhernakova Debby P.Y. Koonen Rinse K. Weersma Daan J. TOUW Folkert Kuipers Cisca Wijmenga Jingyuan Fu 2018Protein & Cell2018,9,5:7
2Neuroimmunoendocrine mechanisms of protective effects of medicalrehabilitation in elderly patients显示文摘Il'nitski- AN Proshchaev KI Zhernakova NI 2009Advances in Gerontology2009,23,2:1
3Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signaling显示文摘Trynka G Zhernakova A Romanos J 2009Gut2009,58,8:1
4Haplotype-based anal- ysis of ulcerative colitis risk loci identifies both IL2 and IL21 as susceptibility genes in Han Chinese 显示文摘Shi J Zhou L Zhernakova A 2011Inflamm Bowel Dis2011,17,:1
5Detecting shared pathogenesis from the shared genetics of immune- related diseases显示文摘Zhernakova A van Diemen CC Wijmenga C 2009Nat Rev Genet2009,10,1:1
6Association of the TGF-beta receptor genes with abdominal aortic aneurysm显示文摘Baas AF Medic J van't Slot R de Kovel CG Zhernakova A Geelkerken RH 2010Eur J Hum Genet2010,18,2:1
7Novel asso- ciation in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases显示文摘Zhernakova A Alizadeh BZ Bevova M 2007Am J Hum Genet2007,81,6:1
8Evolutionary and Functional Analysis of Celiac Risk Loci Reveals SH2B3 as a Protective Factor against Bacterial Infection显示文摘Alexandra Zhernakova Clara C. Elbers Bart Ferwerda Jihane Romanos Gosia Trynka Patrick C. Dubois Carolien G.F. de Kovel Lude Franke Marije Oosting Donatella Barisani Maria Teresa Bardella Leo A.B. Joosten Paivi Saavalainen David A. van Heel Carlo Catassi 2010The American Journal of Human Genetics2010,,6:1
9Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP显示文摘Zhernakova A Festen EM Franke L 2008Am J Hum Genet2008,82,5:1
10Association of variants of transcription factor 7like 2 (TCF7L2) with susceptibility to type 2 diabetes in the Dutch Breda cohort显示文摘 Shiri-Sverdlov R Zhernakova A 2007Diabetologia2007,50,1:1
11Genetic analysis of innate immunity in Croh's disease and ulcerative colitis identifies two loci harboring CARD9 and IL18RAP显示文摘Zhernakova A Festen EM Franke L 0,,05:1
12Evolutionary and Functional Analysis of Celiac Risk Loci Reveals SH2B3 as a Protective Factor against Bacterial Infection显示文摘Alexandra Zhernakova Clara C. Elbers Bart Ferwerda Jihane Romanos Gosia Trynka Patrick C. Dubois Carolien G.F. de Kovel Lude Franke Marije Oosting Donatella Barisani Maria Teresa Bardella Leo A.B. Joosten Paivi Saavalainen David A. van Heel Carlo Catassi 2010The American Journal of Human Genetics2010,,6:1
13Newly identified genetic risk variants for celiac disease related to the immune response 显示文摘Hunt KA Zhernakova A Turner G 2008Nat Genet2008,40,4:1
14Genetic variants ofRANTES are assoc-iated with serum RANTES level and protection for type 1 diabetes显示文摘Zhernakova A Alizadeh BZ Eerligh P 2006Genes Immun2006,7,7:1
15Genetic variants in the region of the C 1 q genes are associated with rheumatoid arthritis显示文摘L. A. Trouw N. Daha F. A. S. Kurreeman S. B?hringer G. N. Goulielmos H. J. Westra A. Zhernakova L. Franke E. A. Stahl E. W. N. Levarht G. Stoeken‐Rijsbergen W. Verduijn A. Roos Y. Li J. J. Houwing‐Duistermaat T. W. J. Huizinga R. E. M. Toes 2013Clin Exp Immunol2013,,1:1
16CTLA4 is differentially associated with autoimmune diseases in the Dutch population 显示文摘Zhernakova A Eerligh P Barrera P 2005Hum Genet2005,118,:1
17Genetic variants of RANTES are associated with serum RANTES level and protection for type 1 diabetes 显示文摘ZHERNAKOVA A ALIZADEH B Z EERLIGH P 2006Genes Immun2006,7,7:1
18Analysis of HLA and Non-HLA Alleles Can Identify Individuals at High Risk for Celiac Disease显示文摘Jihane Romanos Cleo C. van Diemen Ilja M. Nolte Gosia Trynka Alexandra Zhernakova Jingyuan Fu Maria Teresa Bardella Donatella Barisani Ross McManus David A. van Heel Cisca Wijmenga 2009Gastroenterology2009,,3:1
19CTLA4+ 49 A/G and CT60 polymorphisms in Dutch coeliac disease patients 显示文摘Van Belzen M J Mulder C J J Zhernakova A 2004European J Human Genetics2004,12,9:1
20Genetic variants of RANTES are associated with serum RANTES level and protection for type 1 diabetes 显示文摘ZHERNAKOVA A ALIZADEH B Z EERLIGH P 2006Genes Immun2006,7,7:1
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