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| 1 | Sporadic fundic gland polyps are not associated with proton pump inhibitors therapy but negatively correlate with Helicobacter pylori infection in China显示文摘 | Cao Hailong Qu Rui Zhang Zhihua Kong Xinyue Wang Shan Jiang Kui Wang Bangmao | 2014 | Chinese Medical Journal2014，，7： | 29 |
| 2 | 基于ZigBee技术的无线数据采集系统设计显示文摘提出了一种新型的基于ZigBee技术的无线数据采集系统,详细介绍了其系统结构和各个子模块的硬件电路设计及软件流程设计。系统以自带Zigbee/IEEE802.15.4协议的JN5121-MO006模块为核心,以AT45DB081A作为外部存储器,利用FYD12864-0402B输出图形文字信息,同时还采用了SPCE061A芯片来处理语音数据,其目的在于克服有线网络的局限性,并避免其他无线通信技术高功耗的缺点。 | 刘映辉 樊晓平 张纯和 刘少强 Zhihua Qu | 2008 | 工业控制计算机2008，21，8： | 15 |
| 3 | Exosomes secreted from cardiomyocytes suppress the sensitivity of tumor ferroptosis in ischemic heart failure显示文摘Heart failure(HF)patients in general have a higher risk of developing cancer.Several animal studies have indicated that cardiac remodeling and HF remarkably accelerate tumor progression,highlighting a cause-and-effect relationship between these two disease entities.Targeting ferroptosis,a prevailing form of non-apoptotic cell death,has been considered a promising therapeutic strategy for human cancers.Exosomes critically contribute to proximal and distant organ-organ communications and play crucial roles in regulating diseases in a paracrine manner.However,whether exosomes control the sensitivity of cancer to ferroptosis via regulating the cardiomyocyte-tumor cell crosstalk in ischemic HF has not yet been explored.Here,we demonstrate that myocardial infarction(MI)decreased the sensitivity of cancer cells to the canonical ferroptosis activator erastin or imidazole ketone erastin in a mouse model of xenograft tumor.Post-MI plasma exosomes potently blunted the sensitivity of tumor cells to ferroptosis inducers both in vitro in mouse Lewis lung carcinoma cell line LLC and osteosarcoma cell line K7M2 and in vivo with xenograft tumorigenesis model.The expression of miR-22-3p in cardiomyocytes and plasma-exosomes was significantly upregulated in the failing hearts of mice with chronic MI and of HF patients as well.Incubation of tumor cells with the exosomes isolated from post-MI mouse plasma or overexpression of miR-22-3p alone abrogated erastin-induced ferroptotic cell death in vitro.Cardiomyocyte-enriched miR-22-3p was packaged in exosomes and transferred into tumor cells.Inhibition of cardiomyocyte-specific miR-22-3p by AAV9 sponge increased the sensitivity of cancer cells to ferroptosis.ACSL4,a pro-ferroptotic gene,was experimentally established as a target of miR-22-3p in tumor cells.Taken together,our findings uncovered for the first time that MI suppresses erastin-induced ferroptosis through releasing miR-22-3p-enriched exosomes derived from cardiomyocytes.Therefore,targeting exosome-mediated cardiomyocyte/tumor pathological communication may offer a novel approach for the ferroptosis-based antitumor therapy. | Ye Yuan Zhongting Mei Zhezhe Qu Guanghui Li Shuting Yu Yingqi Liu Kuiwu Liu Zhihua Shen Jiaying Pu Yanquan Wang Changhao Wang Zhiyong Sun Qian Liu Xiaochen Pang Ao Wang Zijing Ren Tong Wang Ying Liu Jinhuan Hong Jiajie Xie Xin Li Zhonghua Wang Weijie Du Baofeng Yang | 2023 | Signal Transduction and Targeted Therapy2023，8，4： | 2 |
| 4 | Robust control design for nonlinear uncertain systems without generalized matching conditions 显示文摘 | Zhihua Qu | 1995 | IEEE Trans Automat Control1995，40，8： | 1 |
| 5 | Lyapunov recursive design of robust adaptive tracking control with L2-gain performance for electrically-driven robot manipulators显示文摘 | Chiharu Ishii Tielong Shen Zhihua Qu | 2001 | International Journal of Control2001，，8： | 1 |
| 6 | Robust fault - tolerant self- recovering control of nonlinear uncertain systems显示文摘 | Qu Zhihua Curtis M I Jin Yufang | 2003 | Automatica2003，39，： | 1 |
| 7 | Robust faulttolerant self-recovering control of nonlinear uncertain systems显示文摘 | Qu Zhihua Ihlefeld C M Jin Yufang | 2003 | Automatica2003，39，10： | 1 |
| 8 | Robust learning control for robotic manipulators with an extension to a class of non-linear systems显示文摘 | XU Jianxin VISWANATHAN B QU ZHIHUA | 2000 | International Journal of Control2000，73，10： | 1 |
| 9 | Load-reversed push-out tests on rectangular CFST columns显示文摘 | Xiushu Qu Zhihua Chen David A. Nethercot Leroy Gardner Marios Theofanous | 2013 | Journal of Constructional Steel Research2013，，： | 1 |
| 10 | A nonlinear robust HVDC control for a parallel AC/DC power system显示文摘 | CAI Hongzhi QU Zhihua GAN Deqiang | 2003 | Computers and Electrical Engineering2003，29，： | 1 |
| 11 | Cooperative control of dynamical systems with application to autonomous vehicles显示文摘 | Zhihua Qu Jing Wang Hull R A | 2008 | IEEE Trans on Automatic Control2008，53，4： | 1 |
| 12 | Power efficient multimodulus programmable frequency divider with half-integer division ratio step size显示文摘 | Wang Shengyang Zhu Jiafeng Qu Zhihua | 2009 | Electronics Circuits and Systems2009，25，9： | 1 |
| 13 | Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation显示文摘 | Yang Zhao Xiaolei Yin Han Qin Fangfang Zhu Haisong Liu Weifeng Yang Qiang Zhang Chengang Xiang Pingping Hou Zhihua Song Yanxia Liu Jun Yong Pengbo Zhang Jun Cai Meng Liu Honggang Li Yanqin Li Xiuxia Qu Kai Cui Weiqi Zhang Tingting Xiang Yetao Wu Yiding Zh | 2008 | Cell Stem Cell2008，，5： | 1 |
| 14 | Robust Control of Nonlinear Uncertain Systems under Generalized Matching Conditions 显示文摘 | Qu Zhihua | 1993 | Automatic1993，29，4： | 1 |
| 15 | A nonlinear robust HVDC control for a parallel AC/DC power system 显示文摘 | CAI Hongzhi QU Zhihua GAN Deqiang | 2003 | Computers & Electrical Engineering2003，29，1： | 1 |
| 16 | Robust iterafive learning control for a class of nonlinear systems显示文摘 | Xu Jianxin Qu Zhihua | 1998 | Automatic1998，34，8： | 1 |
| 17 | Cascaded feedback linearization and its application to stabilization of nonholonomic systems 显示文摘 | Wang Jing Qu Zhihua Hull A Richard | 2007 | Systems & Control Letters2007，56，4： | 1 |
| 18 | A global-stabilizing near-optimal control design for nonholonomic chained systems 显示文摘 | Qu Zhihua Wang Jing Plaisted Clinton E | 2006 | IEEE Transactions on Automatic Control2006，51，9： | 1 |
| 19 | A New Analytical Solution to Mobile Robot Trajectory Generation in the Presence of Moving Obstacles 显示文摘 | Qu Zhihua Wang Jing Plaisted Clinton E | 2004 | IEEE Transactions on Robotics2004，20，6： | 1 |
| 20 | Distribution trends of gastric polyps: An endoscopy database analysis of 24?121 northern Chinese patients显示文摘 | Hailong Cao Bangmao Wang Zhihua Zhang Hui Zhang Rui Qu | 2012 | Journal of Gastroenterology and Hepatology2012，，7： | 1 |
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