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| 1 | MicroRNA-21 targets tumor suppressor genes in invasion and metastasis显示文摘MicroRNAs (miRNAs ) 是在 post-transcriptional 指向编码蛋白质的 mRNAs 的小非编码的 RNA 铺平的自然地发生的一个班。我们的以前的研究建议 mir-21 作为 oncogene 工作并且在 tumorigenesis 有一个角色,部分地通过肿瘤的规定压制或基因对流肌浆球蛋白 1 (TPM1 ) 。给那 TPM1 在房间移植被含有,在我们进一步调查了的这研究在房间侵略和肿瘤转移的 mir-21 的角色。我们发现在变形乳癌 MDA-MB-231 房间的 mir-21 的抑制显著地减少了侵略和肺转移。与这一致, TPM1 的宫外的表示显著地减少了房间侵略。而且,我们识别了二个另外的直接 mir-21 目标,规划房间死亡 4 (PDCD4 ) 并且妈大头针,哪个在侵略和转移被含有。象 TPM1 一样, PDCD4 和妈大头针也减少了 MDA-MB-231 房间的侵略海角。最后, PDCD4 的表示和妈大头针相反地在人的胸肿瘤标本与 mir-21 表示相关,显示由在这些肿瘤的 mir-21 的 PDCD4 和妈大头针的潜在的规定。总起来说,结果建议作为 oncogenic miRNA, mir-21 由指向多重肿瘤 / 转移不仅在肿瘤生长而且在侵略和肿瘤转移有一个角色压制或基因。因此, mir-21 的抑制可以为先进癌症的治疗提供一条新奇途径。 | Shuomin Zhu Hailong Wu Fangting Wu Daotai Nie Shijie Sheng Yin-Yuan Mo | 2008 | Cell Research2008，18，3： | 205 |
| 2 | Suppression of cell growth and invasion by miR-205 in breast cancer显示文摘MicroRNAs (miRNAs ) 内长的、小、非编码的 RNA,它能够在 post-transcriptional 的 silencing 基因表示铺平。在这研究,我们报导 miR-205 是显著地在与匹配的正常的胸织物相比的胸肿瘤的 underexpressed。同样,包括 MCF-7 和 MDA-MB-231,乳癌房间行比非恶意的 MCF-10A 房间表示低级 miR-205。兴趣, miR-205 的宫外的表示显著地禁止房间增长和抛锚独立人士生长,以及房间侵略。而且, miR-205 被显示在一个动物模型压制肺转移。最后,西方的污点与试金表明的酶记者结合了那 ErbB3 和脉管的 endothelial 生长因素 A ( VEGF --一)是为 miR-205 的直接目标,并且这 miR-205-mediated 抑制通过和在 ErbB3 和 VEGF 的 3 鈥? untranslated 区域( 3 鈥? UTR )的通常认为的 miR-205 绑定地点的直接相互作用是可能的--一。一起,这些结果建议 miR-205 是在乳癌的肿瘤 suppressor。 | Hailong Wu Shoumin Zhu Yin-Yuan Mo | 2009 | Cell Research2009，19，4： | 56 |
| 3 | A scientometric review of biochar research in the past 20 years(1998-2018)显示文摘Biochar is the carbon-rich product obtained from the thermochemical conversion of biomass under oxygen-limited conditions.Biochar has attained extensive attention due to its agronomical and environmental benefits in agro-ecosystems.This work adopts the scientometric analysis method to assess the development trends of biochar research based on the literature data retrieved from the Web of Science over the period of 1998-2018.By analysing the basic characteristics of 6934 publications,we found that the number of publications grew rapidly since 2010.Based on a keyword analysis,it is concluded that scholars have had a fundamental recognition of biochar and preliminarily found that biochar application had agronomic and environmental benefits during the period of 1998-2010.The clustering results of keywords in documents published during 2011-2015 showed that the main research hotspots were“biochar production”,“biochar and global climate change”,“soil quality and plant growth”,“organic pollutants removal”,and“heavy metals immobilization”.While in 2016-2018,beside these five main research hotspots,“biochar and composting”topic had also received greater attention,indicating that biochar utilization in organic solid waste composting is the current research hotspot.Moreover,updated reactors(e.g.,microwave reactor,fixed-bed reactor,screw-feeding reactor,bubbling fluidized bed reactor,etc.)or technologies(e.g.,solar pyrolysis,Thermo-Catalytic Reforming process,liquefaction technology,etc.)applied for efficient energy production and modified biochar for environmental remediation have been extensively studied recently.The findings may help the new researchers to seize the research frontier in the biochar field. | Ping Wu Syed Tahir Ata-Ul-Karim Bhupinder Pal Singh Hailong Wang Tongliang Wu Cun Liu Guodong Fang Dongmei Zhou Yujun Wang Wenfu Chen | 2019 | Biochar2019，1，1： | 36 |
| 4 | Response of microbial communities to biochar-amended soils:a critical review显示文摘Application of biochar to soils changes soil physicochemical properties and stimulates the activities of soil microorganisms that influence soil quality and plant performance.Studying the response of soil microbial communities to biochar amendments is important for better understanding interactions of biochar with soil,as well as plants.However,the effect of biochar on soil microorganisms has received less attention than its influences on soil physicochemical properties.In this review,the following key questions are discussed:(i)how does biochar affect soil microbial activities,in particular soil carbon(C)mineralization,nutrient cycling,and enzyme activities?(ii)how do microorganisms respond to biochar amendment in contaminated soils?and(iii)what is the role of biochar as a growth promoter for soil microorganisms?Many studies have demonstrated that biochar-soil application enhances the soil microbial biomass with substantial changes in microbial community composition.Biochar amendment changes microbial habitats,directly or indirectly affects microbial metabolic activities,and modifies the soil microbial community in terms of their diversity and abundance.However,chemical properties of biochar,(especially pH and nutrient content),and physical properties such as pore size,pore volume,and specific surface area play significant roles in determining the efficacy of biochar on microbial performance as biochar provides suitable habitats for microorgan-isms.The mode of action of biochar leading to stimulation of microbial activities is complex and is influenced by the nature of biochar as well as soil conditions. | Kumuduni Niroshika Palansooriya James Tsz Fung Wong Yohey Hashimoto Longbin Huang Jörg Rinklebe Scott X.Chang Nanthi Bolan Hailong Wang Yong Sik Ok | 2019 | Biochar2019，1，1： | 34 |
| 5 | Sporadic fundic gland polyps are not associated with proton pump inhibitors therapy but negatively correlate with Helicobacter pylori infection in China显示文摘 | Cao Hailong Qu Rui Zhang Zhihua Kong Xinyue Wang Shan Jiang Kui Wang Bangmao | 2014 | Chinese Medical Journal2014，，7： | 29 |
| 6 | High-entropy ceramics:Present status,challenges,and a look forward显示文摘High-entropy ceramics (HECs) are solid solutions of inorganic compounds with one or more Wyckoff sites shared by equal or near-equal atomic ratios of multi-principal elements.Although in the infant stage,the emerging of this new family of materials has brought new opportunities for material design and property tailoring.Distinct from metals,the diversity in crystal structure and electronic structure of ceramics provides huge space for properties tuning through band structure engineering and phonon engineering.Aside from strengthening,hardening,and low thermal conductivity that have already been found in high-entropy alloys,new properties like colossal dielectric constant,super ionic conductivity,severe anisotropic thermal expansion coefficient,strong electromagnetic wave absorption,etc.,have been discovered in HECs.As a response to the rapid development in this nascent field,this article gives a comprehensive review on the structure features,theoretical methods for stability and property prediction,processing routes,novel properties,and prospective applications of HECs.The challenges on processing,characterization,and property predictions are also emphasized.Finally,future directions for new material exploration,novel processing,fundamental understanding,in-depth characterization,and database assessments are given. | Huimin XIANG Yan XING Fu-zhi DAI Hongjie WANG Lei SU Lei MIAO Guojun ZHANG Yiguang WANG Xiwei QI Lei YAO Hailong WANG Biao ZHAO Jianqiang LI Yanchun ZHOU | 2021 | Journal of Advanced Ceramics2021，10，3： | 28 |
| 7 | 海洋天然气水合物开采潜力地质评价指标研究:理论与方法显示文摘中国南海北部大陆坡具有良好的天然气水合物(以下简称水合物)资源前景,但目前还没有针对海洋水合物藏开采潜力的地质评价指标,无法对水合物藏进行简单高效的开采潜力评价预测。为此,重点分析了与产气潜力密切相关的地质参数(水合物层的孔隙度,水合物初始饱和度,储层渗透率,导热系数,储层上、下盖层的渗透性,储层的初始温度和初始压力)对产气潜力的影响情况。结果发现,在其他条件和参数不变的情况下:①水合物储层孔隙度越大,水合物分解产气速率越快;②水合物饱和度越高,初始产气效率较低,但总体产气开发效益较高;③水合物储层绝对渗透率越大,水合物分解和产气效率越高;④水合物储层导热系数对水合物分解产气效率影响不大;⑤盖层的存在有利于提高水合物的分解效率和气体的长期稳定生产;⑥水合物储层初始温度越高越有利于水合物快速分解;⑦当地层初始压力越高且离水合物相平衡边界越近时,水合物藏产气开发效率也越高。在此基础上,提出了水合物开采潜力地质评价指标研究的目标、内容、技术路线和方法。 | 吴能友 黄丽 苏正 杨胜雄 王宏斌 梁金强 LU Hailong | 2013 | 天然气工业2013，33，7： | 25 |
| 8 | Chemical vapor deposition growth of monolayer MoSe2 nanosheets显示文摘 | Jonathan C. Shaw Hailong Zhou Yu Chen Nathan O. Weiss Yuan Liu Yu Huang Xiangfeng Duan | 2014 | Nano Research2014，7，4： | 26 |
| 9 | Application of LICOM to the numerical study of the water exchange between the South China Sea and its adjacent oceans显示文摘On the basis of 900-year integration of a global ocean circulation model—LICOM driven by ECMWF reanalysis wind data with uni-form 0.5°-grids, a quantitative estimate of the annual and monthly mean water exchange of the South China Sea (SCS) with its adjacentoceans through 5 straits is obtained. Among them, the annual transport is the largest in the Luzon Strait, then in the Taiwan Strait, andthen in the Sunda Shelf, in the Balabac Strait and in the Mindoro Strait in turn, the largest monthly transport variation appears in theLuzon Strait and Sunda shelf. It is shown that the mass transport through the Taiwan Strait is affected by monsoon, while the transportthrough the Luzon Strait may be associated with the bifurcation position of the North Equatorial Current off the east Philippines shore;the transports in the Luzon Strait and Sunda Shelf are out of phase in direction but well correlated in magnitude. The annual andmonthly mean heat and salinity exchange of the SCS through the straits are also calculated and shown to be in phase with the masstransport. The Kuroshio water carries about 0.43 PW heat transport and 151.33 kt/s salinity transport into the SCS, while most of themis carried out of the SCS through the Taiwan Strait and Sunda Shelf annually. The further model integration based on the 900-year inte-gration for another 44 a from 1958 to 2001 driven by real wind data (ERA40 data) shows that the monthly mean mass transport viathese straits varies annually with a large variation range, which may be associated with the seasonal and interannual variations in thecurrent field and sea surface height in the SCS. The mean mass transport through the Taiwan Strait, Luzon Strait, Mindoro Strait, Bal-abac Strait and Sunda Shelf is 2.012 × 106, -4.063 × 106, -0.124 × 106, -0.083 × 106 and 2.258 × 106 m3/s, respectively. | CAI Shuqun LIU Hailong LI Wei LONG Xiaomin | 2005 | Acta Oceanologica Sinica2005，24，4： | 24 |
| 10 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 11 | The Yanshan orogeny and late Mesozoic multi-plate convergence in East Asia—Commemorating 90th years of the “Yanshan Orogeny”显示文摘The Yanshan movement/orogeny has been proposed for 90 years, which is of special significance in the history of geological research in China. This study conducted a review by synthesizing major achievements regarding episodic deformation features, sedimentary and magmatic records of the Yanshan orogeny in China, and clarified the episodic tectono-magmatism and its geodynamic origins. The tectonic implications of the Yanshan orogeny are discussed in the context of global plate tectonics and supercontinent reconstruction. Lines of evidence from structural, sedimentary and magmatic data suggest that the Yanshan orogeny represents a regional-scale tectonic event that affected the entire China continent in late Mesozoic period. Numerous age and structural constraints consistently indicate that the Yanshan orogeny was initiated in the Jurassic(at ~170±5 Ma). and was characterized by alternating stages of crustal shortening at ~170–136 Ma, crustal extension at ~135–90 Ma, and weak shortening at ~80 Ma. The 170–136 Ma crustal shortening was reflected in the generation of two regional stratigraphic unconformities(the Tiaojishan and Zhangjiakou unconformities), which were initially named the A and B episodes of 'the Yanshan Orogeny' by Mr.Wong Wenhao in 1928. Geodynamically, the Yanshan orogeny in East Asia was associated with nearly coeval oceanic subduction and continental convergence in the Paleo-Pacific, Neo-Tethys, and Mongol-Okhotsk tectonic domains. As a consequence, three giant accretionary-collisional tectonic systems were formed along the continental margins of East Asia, i.e., the Mongol-Okhotsk, Bangonghu-Nujiang, and SE China subduction-and collision-related accretionary systems. The Yanshan orogeny induced widespread crustal-scale folding and thrusting, tectonic reactivation of long-lived zones of crustal weakness,and extensive magmatism and mineralization in intraplate regions. Based on the time principle of supercontinent assembly and break-up, we propose that the mid-Late Jurassic multi-plate convergence in East Asia might represent the initiation of the assembly of the Amasia supercontinent, and the Yanshan orogeny might be the first 'stirrings' that is a prerequisite for the birth of the Amasia supercontinent. | Shuwen DONG Yueqiao ZHANG Hailong LI Wei SHI Huaimin XUE Jianhua LI Shiqi HUANG Yongchao WANG | 2018 | Science China Earth Sciences2018，61，12： | 21 |
| 12 | HiQoS:An SDN-Based Multipath QoS Solution显示文摘Today's Internet architecture provides only 'best effort' services,thus it cannot guarantee quality of service(QoS) for applications.Software Defined Network(SDN)is a new approach to computer networking that separates control plane and forwarding planes,and has the advantage of centralized control and programmability.In this paper,we propose HiQoS that provides QoS guarantees using SDN.Moreover,HiQoS makes use of multiple paths between source and destination and queuing mechanisms to guarantee QoS for different types of traffic.Experimental results show that our HiQoS scheme can reduce delay and increase throughput to guarantee QoS.Very importantly,HiQoS recovers from link failure very quickly by rerouting traffic from failed path to other available path. | YAN Jinyao ZHANG Hailong SHUAI Qianjun LIU Bo GUO Xiao | 2015 | China Communications2015，12，5： | 19 |
| 13 | A quasi-global 1/10° eddy-resolving ocean general circulation model and its preliminary results显示文摘In this study,a quasi-global(excluding the Arctic Ocean) eddy-resolving ocean general circulation model(OGCM) is established based on the latest version of the LASG/IAP Climate system Ocean Model(LICOM2.0).The horizontal resolution and vertical resolution are increased to 1/10° and 55 layers,respectively.Forced by the surface fluxes from the reanalysis and observed data,the model has been integrated for approximately 20 model years(20 a).During the last 8 a,the model is driven by daily mean wind stresses from QuikSCAT and heat fluxes from reanalysis data from 2000 to 2007.The basic performance of the OGCM is analyzed using the last 8 a simulation output.Compared with the simulation of the coarse-resolution OGCM,the eddy-resolving OGCM not only better simulates the spatial-temporal features of mesoscale eddies and the paths and positions of western boundary currents but also reproduces the large meander of the Kuroshio Current and its interannual variability.Another aspect,namely,the complex structures of equatorial Pacific currents and currents in the coastal ocean of China,are better captured due to the increased horizontal and vertical resolution. | YU YongQiang LIU HaiLong LIN PengFei | 2012 | Chinese Science Bulletin2012，57，30： | 18 |
| 14 | Biomarker reconstruction of phytoplankton productiv-ity and community structure changes in the middle Okinawa Trough during the last 15 ka显示文摘Biomarkers have been widely used to reconstruct phytoplankton productivity and community structure changes, and this method has been applied for the first time in the middle Okinawa Trough during the transition from the last deglaciation to the Holocene. The total content of all marine phytoplankton biomarkers, used as a total productivity indicator, reveals higher productivity during the deglaciation. The ratios of the biomarkers are used as community structure indicators which show that, compared with the Holocene, the contribution from haptophytes decreased while the contributions from diatoms and dinoflagellates increased during the deglaciation. The increased productivity during the deglacia- tion was likely caused by the stronger winter monsoon. Also increased nutrient supply from terrestrial sources contributes to the higher productivity due to lower sea-level, which is consistent with higher terrestrial biomarker (long-chain n-alkanols) content. These changes in the nutrient supply also con- tributed to the community structure changes in the Okinawa Trough. | XING Lei ZHAO MeiXun ZHANG HaiLong LIU YanGuang SHI XueFa | 2008 | Chinese Science Bulletin2008，53，16： | 17 |
| 15 | Light-absorbing Particles in Snow and Ice: Measurement and Modeling of Climatic and Hydrological impact显示文摘Light absorbing particles(LAP, e.g., black carbon, brown carbon, and dust) influence water and energy budgets of the atmosphere and snowpack in multiple ways. In addition to their effects associated with atmospheric heating by absorption of solar radiation and interactions with clouds, LAP in snow on land and ice can reduce the surface reflectance(a.k.a., surface darkening), which is likely to accelerate the snow aging process and further reduces snow albedo and increases the speed of snowpack melt. LAP in snow and ice(LAPSI) has been identified as one of major forcings affecting climate change, e.g.in the fourth and fifth assessment reports of IPCC. However, the uncertainty level in quantifying this effect remains very high. In this review paper, we document various technical methods of measuring LAPSI and review the progress made in measuring the LAPSI in Arctic, Tibetan Plateau and other mid-latitude regions. We also report the progress in modeling the mass concentrations, albedo reduction, radiative forcing, and climatic and hydrological impact of LAPSI at global and regional scales. Finally we identify some research needs for reducing the uncertainties in the impact of LAPSI on global and regional climate and the hydrological cycle. | Yun QIAN Teppei J.YASUNARI Sarah J.DOHERTY Mark G.FLANNER William K.M.LAU MING Jing Hailong WANG Mo WANG Stephen G.WARREN Rudong ZHANG | 2015 | Advances in Atmospheric Sciences2015，32，1： | 16 |
| 16 | Numerical Simulation of a Planing Vessel at High Speed显示文摘计划容器处于民用、军事的状况广泛地被使用。由于他们的高速度,计划容器的运动是复杂的。以便预言计划容器的运动,分析以高速度计划容器的水动力学表演是重要的。计算液体动态方法(CFD ) 被建议了计算计划容器的水动力学性能。在很传统的 CFD 途径,然而,模型测试或实验公式被需要在计算前获得计划容器的跑的态度。这份报纸论述一个新 CFD 方法计算计划容器的水动力学力量。数字方法基于平均 Reynolds 的海军司烧(RANS ) 方程。液体(VOF ) 的体积方法和 six-degrees-of-freedom 方程被使用。一个有效过程被介绍在数字模拟解决数字分叉问题。与试验性的结果相比,数字模拟结果显示跑的态度和水动力学性能能以高速度被预言很好。 | Yumin Su Qingtong Chen Hailong Shen Wei Lu | 2012 | Journal of Marine Science and Application2012，11，2： | 15 |
| 17 | Development of pyrF-based gene knockout systems for genome-wide manipulation of the archaea Haloferax mediterranei and Haloarcula hispanica显示文摘haloarchaea Haloferax mediterranei 和 Haloarcula hispanica 两个都是在领域 Archaea 的 polyhydroxyalkanoate 制片人,并且他们由于他们的唯一的基因、新陈代谢的特征为研究和生物工学正在变得逐渐地漂亮。加速他们的染色体级的基因、新陈代谢的分析,我们为这二 haloarchaea 开发了特定、高度有效的基因大美人系统。这些基因大美人系统作为选择标记和 uracil 与 pyrF 基因由自杀 plasmid 向量组成营养缺陷型的 haloarchaeon (pyrF ) 作为主人。为目标基因的在里面框架删除,带目标基因的 flanking 区域的自杀 plasmid 被变成相应 pyrF 主人。在没有双转线路的 uracil 和 counterselection 中等的 AS-168SY 上的单个转线路的集成 recombinants (突然发生在里面) 的积极选择以后有 5-fluoroorotic 酸(5-FOA ) 的切除 pyrF 的 recombinants (突然发生外面) ,目标基因大美人异种被 PCR 和南部的污点分析证实。我们由击倒把 phytoene synthase 编码为这些 haloarchaea 的 crtB 基因表明了这些系统的有效性。在结论,这些开发得好的猛烈系统将极大地加速这些 halophilic archaea 的功能的 genomic 研究。 | Hailong Liu Jing Han Xiaoqing Liu Jian Zhou Hua Xiang | 2011 | Journal of Genetics and Genomics2011，38，6： | 14 |
| 18 | Visualizing the emerging trends of biochar research and applications in 2019:a scientometric analysis and review显示文摘Biochar,derived from thermal pyrolysis of biomass,has been regarded as a low-cost,sustainable and beneficial material and widely applied in agriculture,environment and energy during the last two decades.To elucidate the research status timely and future trends in biochar field,CiteSpace is used to systematically analyze the related literature retrieved from the Web of Science core collection in 2019.Based on the keywords clustering analysis,it was found that“biochar production”,“organic pollutants removal”,“heavy metals immobilization”,“bioremediation”were the main hotspots in research covering biochar.“Bioremediation”is an emerging topic and deserves extensive attention due to its highly effective and environmentally friendly treatment of pollutants.Improving the phytoremediation effect,immobilizing functional microorganisms on biochar,and using microorganisms as raw materials to produce biochar were the common methods of biochar-assisted bioremediation.While studies focused on“soil quality and plant growth”and“biochar and global climate change”decreased,investigations concentrated in the toxicity of biochar to soil biota and ruminants are sustainably growing.Research on direct and catalytic thermal pyrolysis of green waste(mainly microalgae)for biofuels(bio-oil,biodiesel,syngas,etc.)and biochar production is increasing.Converting municipal wastes(e.g.,sewage sludge,fallen leaves)into biochar through pyrolysis was a suitable treatment for municipal waste and became a popular topic in recent time.Moreover,the biochar produced from these municipal wastes exhibited excellent performance in the removal of pollutants from wastewater and soil.This review may help to identify future directions in biochar research and applications. | Ping Wu Zeyu Wang Hailong Wang Nanthi S.Bolan Yujun Wang Wenfu Chen | 2020 | Biochar2020，2，2： | 14 |
| 19 | Matching mechanism analysis on an adaptive cycle engine显示文摘As a novel aero-engine concept,adaptive cycle aero-engines(ACEs) are attracting wide attention in the international aviation industry due to their potential superior task adaptability along a wide flight regime.However,this superior task adaptability can only be demonstrated through proper combined engine control schedule design.It has resulted in an urgent need to investigate the effect of each variable geometry modulation on engine performance and stability.Thus,the aim of this paper is to predict and discuss the effect of each variable geometry modulation on the matching relationship between engine components as well as the overall engine performance at different operating modes,on the basis of a newly developed nonlinear component-based ACE performance model.Results show that at all four working modes,turning down the high pressure compressor variable stator vane,the low pressure turbine variable nozzle,the nozzle throat area,and turning up the core-driven fan stage variable stator vane,the high pressure turbine variable nozzle can increase the thrust at the expense of a higher high pressure turbine inlet total temperature.However,the influences of these adjustments on the trends of various engine components' working points and working lines as well as the ratio of the rotation speed difference are different from each other.The above results provide valuable guidance and advice for engine combined control schedule design. | Zheng Junchao Chen Min Tang Hailong | 2017 | Chinese Journal of Aeronautics2017，30，2： | 14 |
| 20 | Recombinant CC16 protein inhibits the production of pro-inflammatory cytokines via NF-KB and p38 MAPK pathways in LPS-activated RAW264,7 macrophages显示文摘积累的证据显示克莱拉房间 protein-16 (CC16 ) 有反煽动性的功能,尽管深奥分子的小径完全没被阐明。这里,我们评估了效果肿瘤坏死因素 alpha (TNF-) 的表示上的 recombinant 老鼠 CC16 (rCC16 ) , interleukin-6 (IL-6 ) ,和在 lipopolysaccharide (LPS ) 的 IL-8 刺激了老鼠巨噬细胞(RAW264.7 房间) 并且探索了内在的分子的机制。rCC16 在两个禁止了导致 LPS 的 TNF- , IL-6,和 IL-8 表示,这被发现送信人 ribonucleicacid (mRNA ) 水平和蛋白质以一种集中依赖者方式铺平,由即时反向的 transcriptase 聚合酶链反应和连接酶的 immunosorbent 试金示威了。如此的镇压效果被 transcriptional 活动和原子因素(NF ) 的脱氧核糖核酸酸绑定活动的抑制伴随 -B 然而并非使活跃之物蛋白质(AP )-1。西方的污点分析进一步表明 rCC16 禁止了原子 NF-B 和 NF-B 禁止的蛋白质 IB,和 p38 的 cytosolic NF-B, phosphorylation 和减小的减小的增加激活 mitogen 的蛋白质 kinase (MAPK ) 依赖者由在它的 p65 子单元的 Ser276 的 phosphorylation 的 NF-B 激活。而且, rCC16 被发现没另外在c6月N终端 kinase ,c6月,或c-Jun.的原子 translocation 的 phosphorylation 上有效果,TNF-的减小, IL-6 ,并且 IL-8 被颠倒内长的uteroglobin有约束力的蛋白质的水平什么时候被 RNA 干扰在 对待rCC16 、 对待LPS 的 RAW264.7 房间减少。我们的数据建议 rCC16 由在 RAW264.7 房间使 NF-B 和 p38 MAPK 然而并非 AP-1 失去活性压制调停 LPS 的煽动性的调停人 TNF- , IL-6,和 IL-8 生产。 | Min Pang Yangyang Yuan Dong Wang Ting Li Dan Wang Xiaohong Shi Min Guo Chunfang Wang Xinri Zhang Guoping Zheng Baofeng Yu Hailong Wang | 2017 | Acta Biochimica et Biophysica Sinica2017，49，5： | 14 |
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