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| 1 | Genomic insights into the fast growth of paulownias and the formation of Paulownia witches' broom显示文摘Paulownias are among the fastest growing trees in the world,but they often suffer tremendous loss of wood production due to infection by Paulownia witches'broom(PaWB)phytoplasmas.In this study,we have sequenced and assembled a high-quality nuclear genome of Paulownia fortunei,a commonly cultivated paulownia species.The assembled genome of P.fortunei is 511.6 Mb in size,with 93.2%of its sequences anchored to 20 pseudo-chromosomes,and it contains 31985 protein-coding genes.Phylogenomic analyses show that the family Paulowniaceae is sister to a clade composed of Phrymaceae and Orobanchaceae.Higher photosynthetic efficiency is achieved by integrating C3 photosynthesis and the crassulacean acid metabolism pathway,which may contribute to the extremely fast growth habit of paulownia trees.Comparative transcriptome analyses reveal modules related to cambial growth and development,photosynthesis,and defense responses.Additional genome sequencing of PaWB phytoplasma,combined with functional analyses,indicates that the effector PaWB-SAP54 interacts directly with Paulownia PfSPLa,which in turn causes the degradation of PfSPLa by the ubiquitin-mediated pathway and leads to the formation of witches'broom.Taken together,these results provide significant insights into the biology of paulownias and the regulatory mechanism for the formation of PaWB. | Yabing Cao Guiling Sun Xiaoqiao Zhai Pingluo Xu Liming Ma Minjie Deng Zhenli Zhao Haibo Yang Yanpeng Dong Zhonghai Shang Yujie Lv Lijun Yan Haifang Liu Xibing Cao Bingbing Li Zhe Wang Xiaogai Zhao Haiyan Yu Fan Wang Wen Ma Jinling Huang Guoqiang Fan | 2021 | Molecular Plant2021，14，10： | 7 |
| 2 | 自然杀伤T细胞对小鼠肝癌移植瘤的抑制作用(英文)显示文摘Objective:The aim of this study was to investigate the inhibition effect of natural killer T(NKT) cells on transplantation hepatocellular carcinoma in mice.Methods:α-galactosylceramide(α-GalCer)-pulsed DC and Hep S were prepared as stimulus.Hepatoma xenograft model was established and mice were randomly divided into 4 groups(n=13 each group):(1) control group,intravenous injection of the same volume of saline.(2) mature DC group,intravenous injection of mature DC cells(4×106 cells).(3) α-GalCer-pulsed HepS group,intravenous injection of α-GalCer-pulsed HepS(4×106 cells).(4) α-GalCer-pulsed mature DC group,intravenous injection of α-GalCer-pulsed DC(4×106 cells).The changes of tumor volume in mice and survival period were measured every 2 days.Percentage of NKT cells in spleens and cytotoxicity of spleen cells were detected by flow cytometry.Tumor tissues were analyzed by histopathological examination.Results:In α-GalCer-pulsed Heps and DC groups,the average survival period was prolonged and tumor volume was markedly decreased,spleen cells and NKT cells were significantly increased,and tumor necrosis was evident,compared to the control group.Conclusion:α-GalCer-pulsed DC and HepS could activate NKT cells in vivo,also increase NKT cells cytotoxicity,inhibit the growth of hepatomas and prolong survival period. | Fuxing Chen Hongdan Zhao Nanzheng Zhang Junquan Liu Zhonghai Zhou Leiqing Sun Yu Zhou | 2011 | The Chinese-German Journal of Clinical Oncology2011，10，5： | 3 |
| 3 | Effect of chondroitin sulfate proteoglycans on neuronal cell adhesion, spreading and neurite growth in culture显示文摘As one major component of extracellular matrix(ECM) in the central nervous system, chondroitin sulfate proteoglycans(CSPGs) have long been known as inhibitors enriched in the glial scar that prevent axon regeneration after injury. Although many studies have shown that CSPGs inhibited neurite outgrowth in vitro using different types of neurons, the mechanism by which CSPGs inhibit axonal growth remains poorly understood. Using cerebellar granule neuron(CGN) culture, in this study, we evaluated the effects of different concentrations of both immobilized and soluble CSPGs on neuronal growth, including cell adhesion, spreading and neurite growth. Neurite length decreased while CSPGs concentration arised, meanwhile, a decrease in cell density accompanied by an increase in cell aggregates formation was observed. Soluble CSPGs also showed an inhibition on neurite outgrowth, but it required a higher concentration to induce cell aggregates formation than coated CSPGs. We also found that growth cone size was significantly reduced on CSPGs and neuronal cell spreading was restrained by CSPGs, attributing to an inhibition on lamellipodial extension. The effect of CSPGs on neuron adhesion was further evidenced by interference reflection microscopy(IRM) which directly demonstrated that both CGNs and cerebral cortical neurons were more loosely adherent to a CSPG substrate. These data demonstrate that CSPGs have an effect on cell adhesion and spreading in addition to neurite outgrowth. | Jingyu Jin Sharada Tilve Zhonghai Huang Libing Zhou Herbert M.Geller Panpan Yu | 2018 | Neural Regeneration Research2018，13，2： | 2 |
| 4 | Higher Harmonics in Free Electron Laser with a Two-Wavenumber Plane Wiggler Magnetic Field显示文摘The higher harmonics of the free electron laser(FEL)with a two-wavenumber plane wiggler magnetic field,which may induce a lot of higher harmonics,are investigated.Using a two-wavenumber wiggler comprised of two separate periodicities,k_(ω)and k_(ω)+Δk,numerical simulations show that the higher harmonic may be amplified and the first harmonic may be suppressed in this kind of FEL with an optimized parameterΔk.The coupling coefficient and gain coefficient in low-gain regime of the harmonic are also obtained. | LU Bo YANG Zhonghai LIU Shenggang YU Junsheng | 1993 | Chinese Physics Letters1993，10，4： | 1 |
| 5 | Hierarchical top- porous/bottom-tubular TiO2 nanostructures decorated with Pd nanoparticles for efficient photoelectrocatalytic decompo- sition of synergistic pollutants显示文摘 | Zhang Zhonghai Yu Yanjie Wang Peng | 2012 | Am Chem Soc Mater In- terf2012，4，2： | 1 |
| 6 | Visible-blind UV digital camera based on a 32x32 array of GaN/A1GaN p-i-n photodiodes 显示文摘 | Brown J D Yu Zhonghai Mattews J | 1999 | lnternet Journal Nitrite Semiconductor Research1999，4，9： | 1 |
| 7 | Carrier and microstructure tuning for improving the thermoelectric properties of Ag_(8)SnSe_(6)via introducing SnBr_(2)显示文摘The argyrodite compounds(2 A(12)/B X6 m n n^(m+)+--(Am+=Li^(+),Cu^(+),and Ag^(+);Bn^(+)=Ga^(3+),Si^(4+),Ge^(4+),Sn^(4+),P^(5+),and As^(5+);and X^(2−)=S^(2−),Se^(2−),or Te^(2−)))have attracted great attention as excellent thermoelectric(TE)materials due to their extremely low lattice thermal conductivity(κl).Among them,Ag_(8)SnSe_(6)-based TE materials have high potential for TE applications.However,the pristine Ag_(8)SnSe_(6)materials have low carrier concentration(<1017 cm^(−3)),resulting in low power factors.In this study,a hydrothermal method was used to synthesize Ag_(8)SnSe_(6)with high purity,and the introduction of SnBr_(2)into the pristine Ag_(8)SnSe_(6)powders has been used to simultaneously increase the power factor and decrease the thermal conductivity(κ).On the one hand,a portion of the Br−ions acted as electrons to increase the carrier concentration,increasing the power factor to a value of~698 mW·m^(−1)·K^(−2)at 736 K.On the other hand,some of the dislocations and nanoprecipitates(SnBr_(2))were generated,resulting in a decrease ofκl(~0.13 W·m^(−1)·K^(−1))at 578 K.As a result,the zT value reaches~1.42 at 735 K for the sample Ag8Sn1.03Se5.94Br0.06,nearly 30%enhancement in contrast with that of the pristine sample(~1.09).The strategy of synergistic manipulation of carrier concentration and microstructure by introducing halogen compounds could be applied to the argyrodite compounds to improve the TE properties. | Zhonghai YU Xiuxia WANG Chengyan LIU Yiran CHENG Zhongwei ZHANG Ruifan SI Xiaobo BAI Xiaokai HU Jie GAO Ying PENG Lei MIAO | 2022 | Journal of Advanced Ceramics2022，11，7： | 1 |
| 8 | GRB 220408B:A Three-episode Burst from a Precessing Jet显示文摘Jet precession has previously been proposed to explain the apparently repeating features in the light curves of a few gamma-ray bursts(GRBs).In this paper,we further apply the precession model to a bright GRB 220408B by examining both its temporal and spectral consistency with the predictions of the model.As one of the recently confirmed GRBs observed by our GRID CubeSat mission,GRB 220408B is noteworthy as it exhibits three apparently similar emission episodes.Furthermore,the similarities are reinforced by their strong temporal correlations and similar features in terms of spectral evolution and spectral lags.Our analysis demonstrates that these features can be well explained by the modulated emission of a Fast-Rise-Exponential-Decay(FRED)shape light curve intrinsically produced by a precessing jet with a precession period of 18.4_(-0.2)~(+0.2)s,a nutation period of11.1_(-0.2)~(+0.2)s and viewed off-axis.This study provides a straightforward explanation for the complex yet similar multiepisode GRB light curves. | Zijian Zhang Yi-Han Iris Yin Chenyu Wang Xiangyu Ivy Wang Jun Yang Yan-Zhi Meng Zi-Ke Liu Guo-Yin Chen Xiaoping Fu Huaizhong Gao Sihao Li Yihui Liu Xiangyun Long Yong-Chang Ma Xiaofan Pan Yuanze Sun Wei Wu Zirui Yang Zhizhen Ye Xiaoyu Yu Shuheng Zhao Xutao Zheng Tao Zhou Qing-Wen Tang Qiurong Yan Rong Zhou Zhonghai Wang Hua Feng Ming Zeng Bin-Bin Zhang | 2023 | Research in Astronomy and Astrophysics2023，23，11： | 0 |
| 9 | Perpendicular exchange bias of (Pt/Co)_n/FeMn multilayers显示文摘(Pt/Co)n/FeMn multilayers with perpendicular anisotropy (PA) were prepared by magnetron sputtering with Pt as the buffer layer and the capping layer. The dependence of perpendicular exchange bias (PEB), Hex, on the thickness of the FeMn antiferromagnet (AFM) layer is similar to that of in-plane exchange bias. The value of Hex for the (Pt/Co)3/FeMn multilayer reaches 22.3 kA/m. A thin Pt spacer was inserted between the Co/FeMn interface to enhance PEB. The PEB reaches the largest at 39.8 kA/m when the thickness of the Pt spacer is 0.4 nm. | Zhonghai Zhai Yang liu Jiao Teng Baohe Li Guanghua Yu Fengwu Zhu | 2007 | Journal of University of Science and Technology Beijing2007，14，6： | 0 |
| 10 | High-speed all-optic optical coherence tomography and photoacoustic microscopy dual-modal system for microcirculation evaluation显示文摘We propose a high-speed all-optic dual-modal system that integrates spectral domain optical coherence tomography and photoacoustic microscopy(PAM).A 3*3 coupler-based interfer-ometer is used to remotely detect the surface vibration caused by photoacoustic(PA)waves.Three outputs of the interferometer are acquired simultaneously with a multi-channel data ac-quisition card.One channel data with the highest PA signal detection sensitivity is selected for sensitivity compensation.Experiment on the phantom demonstrates that the proposed method can sucessfully compensate for the loss of intensity caused by sensitivity variation.The imaging speed of the PAM is improved compared to our previous system.The total time to image a sample with 256×256 pixels is~20s.Using the proposed system,the microvasculature in the mouse auricle is visualized and the blood flow state is accessed. | Yang Lin Menghan Yu Yi Wang Ziyue Meng Ang Li Zhonghai He Qiaoyun Wang Jian Liu Yao Yu Yuqian Zhao Xin Zhu Zhenhe Ma | 2022 | Journal of Innovative Optical Health Sciences2022，15，4： | 0 |
| 11 | Superior multiphase interfaces in AgCuTe-based composite with significantly enhanced thermoelectric properties显示文摘It is common sense that a phase interface(or grain boundary)could be used to scatter phonons in thermoelectric(TE)materials,resulting in low thermal conductivity(k).However,a large number of impurity phases are always so harmful to the transport of carriers that poor TE performance is obtained.Here,we demonstrate that numerous superior multiphase(AgCuTe,Ag_(−2)Te,copper telluride(Cu_(2)Te and Cu_(2−x)Te),and nickel telluride(NiTe))interfaces with simultaneous strong phonon scattering and weak electron scattering could be realized in AgCuTe-based TE materials.Owing to the similar chemical bonds in these phases,the depletion region at phase interfaces,which acts as carrier scattering centers,could be ignored.Therefore,the power factor(PF)is obviously enhanced from~609 to~832μW·m^(−1)·K^(−2),and k is simultaneously decreased from~0.52 to~0.43 W·m^(−1)·K^(−1) at 636 K.Finally,a peak figure of merit(zT)of~1.23 at 636 K and an average zT(zTavg)of~1.12 in the temperature range of 523–623 K are achieved,which are one of the best values among the AgCuTe-based TE materials.This study could provide new guidance to enhance the performance by designing superior multiphase interfaces in the TE materials. | Wenpei Li Zhonghai Yu Chengyan Liu Ying Peng Baoquan Feng Jie Gao Guojing Wu Xiaobo Bai Junliang Chen Xiaoyang Wang Lei Miao | 2023 | Journal of Advanced Ceramics2023，12，8： | 0 |
| 12 | Convenient Synthesis of 1-Thiohydroxypyrene by Newman-Kwart Rearrangement显示文摘 | ZHANG Ran XU Lihua CHEN Hui QIN Zhihong ZHAO Yu Ni Zhonghai | 2015 | Chemical Research in Chinese Universities2015，31，2： | 0 |
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