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| 1 | Correlation of Gut Microbiome Between ASD Children and Mothers and Potential Biomarkers for Risk Assessment显示文摘Variation of maternal gut microbiota may increase the risk of autism spectrum disorders(ASDs) in offspring. Animal studies have indicated that maternal gut microbiota is related to neurodevelopmental abnormalities in mouse offspring, while it is unclear whether there is a correlation between gut microbiota of ASD children and their mothers. We examined the relationships between gut microbiome profiles of ASD children and those of their mothers, and evaluated the clinical discriminatory power of discovered bacterial biomarkers. Gut microbiome was profiled and evaluated by 16S ribosomal RNA gene sequencing in stool samples of 59 mother–child pairs of ASD children and 30 matched mother–child pairs of healthy children. Significant differences were observed in the gut microbiome composition between ASD and healthy children in our Chinese cohort. Several unique bacterial biomarkers, such as Alcaligenaceae and Acinetobacter, were identified. Mothers of ASD children had more Proteobacteria, Alphaproteobacteria, Moraxellaceae, and Acinetobacter than mothers of healthy children. There was a clear correlation between gut microbiome profiles of children and their mothers; however, children with ASD still had unique bacterial biomarkers, such as Alcaligenaceae, Enterobacteriaceae, and Clostridium. Candidate biomarkers discovered in this study had remarkable discriminatory power. The identified patterns of mother–child gut microbiome profiles may be important for assessing risks during the early stage and planning of personalized treatment and prevention of ASD via microbiota modulation. | Ning Li Junjie Yang Jiaming Zhang Cheng Liang Ying Wang Bin Chen Changying Zhao Jingwen Wang Guangye Zhang Dongmei Zhao Yi Liu Lehai Zhang Jun Yang Guimei Li Zhongtao Gai Lei Zhang Guoping Zhao | 2019 | Genomics, Proteomics & Bioinformatics2019，17，1： | 6 |
| 2 | Lyapunov-based switched-gain impact angle control guidance显示文摘To hit stationary ground targets in specified direction, a nonlinear impact angle control guidance law based on Lyapunov stability theory is proposed. The proposed law ensures the convergence of the heading angle and the miss distance to guarantee a successful engagement. The impact angle can be adjusted by varying a single parameter. And the maximum value of acceleration has been analyzed to get the proper range for control parameter. Considering the achievable impact angle set is limited, an additional phase is added to form a two-phase control strategy.The first phase is to establish a proper initial condition for the second phase, and the second phase is to hit the target with a certain impact angle. An analysis of the proper selection of control parameters to expand the achievable impact angle set is presented. The performance of the proposed guidance law is illustrated with simulations. | Zhongtao CHENG Lei LIU Yongji WANG | 2018 | Chinese Journal of Aeronautics2018，31，4： | 3 |
| 3 | Focusing light into scattering media with ultrasound-induced field perturbation显示文摘Focusing light into scattering media,although challenging,is highly desirable in many realms.With the invention of time-reversed ultrasonically encoded(TRUE)optical focusing,acousto-optic modulation was demonstrated as a promising guidestar mechanism for achieving noninvasive and addressable optical focusing into scattering media.Here,we report a new ultrasound-assisted technique,ultrasound-induced field perturbation optical focusing,abbreviated as UFP.Unlike in conventional TRUE optical focusing,where only the weak frequency-shifted first-order diffracted photons due to acousto-optic modulation are useful,here UFP leverages the brighter zeroth-order photons diffracted by an ultrasonic guidestar as information carriers to guide optical focusing.We find that the zeroth-order diffracted photons,although not frequency-shifted,do have a field perturbation caused by the existence of the ultrasonic guidestar.By detecting and time-reversing the differential field of the frequency-unshifted photons when the ultrasound is alternately ON and OFF,we can focus light to the position where the field perturbation occurs inside the scattering medium.We demonstrate here that UFP optical focusing has superior performance to conventional TRUE optical focusing,which benefits from the more intense zeroth-order photons.We further show that UFP optical focusing can be easily and flexibly developed into double-shot realization or even single-shot realization,which is desirable for high-speed wavefront shaping.This new method upsets conventional thinking on the utility of an ultrasonic guidestar and broadens the horizon of light control in scattering media.We hope that it provides a more efficient and flexible mechanism for implementing ultrasound-guided wavefront shaping. | Zhongtao Cheng Lihong V.Wang | 2021 | Light(Science & Applications)2021，10，9： | 3 |
| 4 | Response surface optimization of fermentation conditions for producing xylanase by Aspergillus niger SL-05 显示文摘 | Liu Cheng Sun Zhongtao Du Jinhua | 2008 | J Ind Microbiol Biotechnol2008，35，： | 1 |
| 5 | Layered manganese phosphorus trisulfides for high-performance lithium-ion batteries and the storage mechanism显示文摘Although advanced anode materials for the lithium-ion battery have been investigated for decades,a reliable,high-capacity,and durable material that can enable a fast charge remains elusive.Herein,we report that a metal phosphorous trichalcogenide of MnPS_(3)(manganese phosphorus trisulfide),endowed with a unique and layered van der Waals structure,is highly beneficial for the fast insertion/extraction of alkali metal ions and can facilitate changes in the buffer volume during cycles with robust structural stability.The few-layered MnPS_(3)anodes displayed the desirable specific capacity and excellent rate chargeability owing to their good electronic and ionic conductivities.When assembled as a half-cell lithium-ion battery,a high reversible capacity of 380 mA h g^(−1)was maintained by the MnPS_(3)after 3000 cycles at a high current density of 4 A g^(−1),with a capacity retention of close to or above 100%.In full-cell testing,a reversible capacity of 450 mA h g^(−1)after 200 cycles was maintained as well.The results of in-situ TEM revealed that MnPS_(3)nanoflakes maintained a high structural integrity without exhibiting any pulverization after undergoing large volumetric expansion for the insertion of a large number of lithium ions.Their kinetics of lithium-ion diffusion,stable structure,and high pseudocapacitance contributed to their comprehensive performance,for example,a high specific capacity,rapid charge-discharge,and long cyclability.MnPS_(3)is thus an efficient anode for the next generation of batteries with a fast charge/discharge capability. | Hailin Shen Yueling Cai Zhongtao Ma Peng Wang Bingkun Guo Jipeng Cheng Qianqian Li Hongtao Wang Zhongyuan Liu Anmin Nie Jinsong Wu | 2023 | Carbon Energy2023，5，3： | 1 |
| 6 | Response surface optimi- zation of fermentation conditions for producing xylanase by Aspergillus niger SL-05显示文摘 | LIU Cheng SUN Zhongtao DU Jinhua | 2008 | J Ind Microbiol Biotechnol2008，35，： | 1 |
| 7 | Dynamic Fracture Analysis for Shale Material by Peridynamic Modelling显示文摘In this work,a bond-based peridynamics(PD)model was built to analyze the dynamic fracture of shale material.Both the the convergence studies and the result of dynamic crack propagation were presented.As well-known,crack propagation,aggregation,and bifurcation play an critical role in the failure analysis of brittle materials such as shale.The dynamic crack propagation and branching analysis of shale by using the PD method were discussed.Firstly,the valid and accuracy of the PD model for the rock materials was verified by comparing with the existed numerical results.Secondly,we discussed the convergence both with uniform grid refinement(m-convergence)and decreasing the peridynamics horizon(δ-convergence).Then the shale material with two pre-crack under uniaxial compression using the present PD model were discussed,and the influence of the different angle of flaws on the behavior of crack propagation was also analyzed.The results shows that both the loading conditions and the angle of flaws can influences the crack propagation in shale. | Zhanqi Cheng Zhenyu Wang Zhongtao Luo | 2019 | Computer Modeling in Engineering & Sciences2019，，3： | 1 |
| 8 | Steam reforming of methane over Ni catalyst in micro-channel reactor显示文摘 | Zhai Xuli Cheng Yinhong Zhang Zhongtao | 2011 | Int J Hydrogen Energy2011，36，12： | 1 |
| 9 | Steam reforming of methane over Ni catalyst in micro-channel reactor显示文摘 | Xuli Zhai Yinhong Cheng Zhongtao Zhang Yong Jin Yi Cheng | 2011 | International Journal of Hydrogen Energy2011，，12： | 1 |
| 10 | Remotely mind-controlled metasurface via brainwaves显示文摘The power of controlling objects with mind has captivated a popular fascination to human beings.One possible path is to employ brain signal collecting technologies together with emerging programmable metasurfaces(PM),whose functions or operating modes can be switched or customized via on-site programming or pre-defined software.Nevertheless,most of existing PMs are wire-connected to users,manually-controlled and not real-time.Here,we propose the concept of remotely mind-controlled metasurface(RMCM)via brainwaves.Rather than DC voltage from power supply or AC voltages from signal generators,the metasurface is controlled by brainwaves collected in real time and transmitted wirelessly from the user.As an example,we demonstrated a RMCM whose scattering pattern can be altered dynamically according to the user’s brain waves via Bluetooth.The attention intensity information is extracted as the control signal and a mapping between attention intensity and scattering pattern of the metasurface is established.With such a framework,we experimentally demonstrated and verified a prototype of such metasurface system which can be remotely controlled by the user to modify its scattering pattern.This work paves a new way to intelligent metasurfaces and may find applications in health monitoring,5G/6G communications,smart sensors,etc. | Ruichao Zhu Jiafu Wang Tianshuo Qiu Yajuan Han Xinmin Fu Yuzhi Shi Xingsi Liu Tonghao Liu Zhongtao Zhang Zuntian Chu Cheng‑Wei Qiu Shaobo Qu | 2022 | eLight2022，2，1： | 1 |
| 11 | Ascent Trajectory Optimization for Air-Breathing Hypersonic Vehicles Based on IGS-MPSP显示文摘This paper proposes an improved Generalized Quasi-Spectral Model Predictive Static Programming(GS-MPSP)algorithm for the ascent trajectory optimization for hypersonic vehicles in a complex°ight environment.The proposed method guarantees the satisfaction of constraints related to the state and control vector while retaining its high computational e±ciency.The spectral representation technique is used to describe the control variables,which reduces the number of decision variables and makes the control input smooth enough.Through Taylor expansion,the constraints are transformed into an inequality containing only decision variables,such that it can be added into GS-MPSP framework.By Gauss quadrature collocation method,only a few collocation points are needed to solve the sensitivity matrix,which greatly accelerates the calculation.Subsequently,the analytical expression is obtained by combining the static optimization with the penalty function method.Finally,the simulation results demonstrate that the proposed improved GS-MPSP algorithm can achieve both high computational e±-ciency and high terminal precision under the constraints.. | Lei Liu Qianwei He Bo Wang Wenzhe Fu Zhongtao Cheng Yongji Wang | 2021 | Guidance, Navigation and Control2021，1，2： | 0 |
| 12 | Amphoteric covalent organic framework as single Li+superionic conductor in all-solid-state显示文摘As a novel class of porous crystalline solids,covalent organic frameworks(COFs)based electrolyte can combine the advantages of both inorganic and polymer electrolytes,leading to such as higher structural stability to inhibit lithium dendrites and better processing facility for improving interfacial contact.However,the ionic components of Li salt tend to be closely associated in the form of ion pairs or even ionic aggregates in the channel of COFs due to strong coulombic interactions,thus resulting in slow ionic diffusion dynamics and low ionic conductivity.Herein,we successfully designed and synthesized a novel single-ion conducting nitrogen hybrid conjugated skeleton(NCS)as all solid electrolyte,whose backbone is consisted with triazine and piperazine rings.A loose bonding between the triazine rings and cations would lower the energy barrier during ions transfer,and electrostatic forces with piperazine rings could“anchor”anions to increase the selectivity during ions transfer.Thus,the NCSelectrolyte exhibits excellent room temperature lithium-ion conductivity up to 1.49 mS·cm−1 and high transference number of 0.84 without employing any solvent,which to the best of our knowledge is one of the highest COF-based electrolytes so far.Moreover,the fabricated all-solid-state lithium metal batteries demonstrate highly attractive properties with quite stable cycling performance over 100 cycles with 82%capacity reservation at 0.5 C. | Zhangzhen Cheng Liping Lu Siyu Zhang Haiyan Liu Tao Xing Yan Lin Hao Ren Zhongtao Li Linjie Zhi Mingbo Wu | 2023 | Nano Research2023，16，1： | 0 |
| 13 | Diffusion behavior and reactions between Al and Ca in Mg alloys by diffusion couples显示文摘The diffusion behavior and reactions between Al and Ca in Mg alloys by diffusion couple method were investigated. Results demonstrate that Al_2Ca is the only phase existing in the diffusion reaction layers.The volume fraction of Al_2Ca in diffusion reaction layers increases linearly with temperature. The standard enthalpy of formation for intermetallic compounds was rationalized on the basis of the Miedema model. Al-Ca intermetallic compounds were preferable to form in the Mg-Al-Ca ternary system under the same conditions. Over the range of 350–400?C, the structure of Al_2Ca is more stable than that of Al_4Ca, Al_(14)Ca_(13) and Al_3Ca_8. The growth constants of the layer Ⅰ, layer Ⅱ and entire diffusion reaction layers were determined. The activation energies for the growth of the layer Ⅰ, layer Ⅱ and entire diffusion reaction layers were(80.74 ± 3.01) k J/mol,(93.45 ± 2.12) k J/mol and(83.52 ± 1.50) k J/mol, respectively.In layer Ⅰ and Ⅱ, Al has higher integrated interdiffusion coefficients D^(Int, layer)ithan Ca. The average effective interdiffusion coefficients D_(Al)^(eff) values are higher than D_(Ca)^(eff) in the layer Ⅰ and Ⅱ. | Jiahong Dai Hong Xiao Bin Jiang Hongmei Xie Cheng Peng Zhongtao Jiang Qin Zou Qingshan Yang Fusheng Pan | 2018 | Journal of Materials Science & Technology2018，34，2： | 0 |
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