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| 1 | Influence of Different Al Contents on Microstructure, Tensile and Wear Properties of Zn-based Alloy显示文摘The influence of different Al contents on the microstructure, hardness, tensile and wear behavior of Zn-based alloys was investigated in the present study. The test results show that alloy with 27% Al content shows the higher ultimate strength and elongation percent at room and elevated temperatures. It also exhibits the higher wear resistance at all loads in view of the higher tightness of Zn-27Al alloy. Increasing Al content from 33% to 48% results in improvement of ultimate strength and elongation percent at room and elevated temperatures. However, the ultimate strength and elongation percent of the ZA48 alloy are still lower than that of Zn-27Al alloys. The reason can be attributed to the increasing segregation and voids with increasing Al contents. | Shuqing Yan Jingpei Xie Zhongxia Liu Wenyan Wang Aiqin Wan Jiwen Li | 2010 | Journal of Materials Science & Technology2010，26，7： | 4 |
| 2 | Rhubarb-based Chinese herbal formulae for hepatic encephalopa-thy:a systematic review and Meta-analysis显示文摘OBJECTIVE: To evaluate the effectiveness and safety of rhubarb-based Chinese herbal formulae(RCHF), which are widely used to treat hepatic encephalopathy(HE) in China.METHODS: Nine online databases were searched from inception to November 22, 2016. Eligible studies were randomized controlled trials of Traditional Chinese Medicine(TCM) treatment for adult patients(≥ 18 years old) with HE. Outcomes such as mortality rate, clinical response rate, blood ammonia level, and alanine aminotransferase were evaluated between TCM group and control group.RESULTS: Thirty studies involving 2661 HE patients were analyzed. Most studies used RCHF treatment.Compared with conventional treatment as usual,lactulose, and vinegar, RCHF were associated with significant improvement in clinical response rate[risk ratio(RR) = 1.33, 95% confidence interval(CI) =1.25, 1.43, I2= 0%; RR = 1.26, 95% CI = 1.14, 1.38, I2=22%; and RR = 1.19, 95% CI = 1.06, 1.33, I2= 0%, respectively] and significant reductions in levels of blood ammonia and alanine aminotransferase. Only minor RCHF-associated adverse events, such as abdominal pain(0.3%), anal tenesmus(0.3%), and diarrhea(2.3%), were reported, and there were no significant differences in these events between the treatment group and the three types of control group.CONCLUSION: The findings suggest that RCHF may be an alternative treatment option for HE patients. More rigorous multicenter studies with larger samples and longer observational periods are needed to confirm these findings. | Zhang Ning Zhou Shuangnan Xiao Xiaohe Wanq Zhen Bai Yunfeng He Tingting Zhou Chao Wang Yao Kun Zhou Wang Zhongxia Liu Bing Larry J.Prokop Matthew C.Hernandez Li Jun Gong Man | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 3 |
| 3 | Clinical characteristics of 96 patients with drug-induced acute liver failure:a comparison between Traditional Chinese and Western Medicine显示文摘OBJECTIVE: To compare the causes, clinical symptoms, laboratory test results, and prognosis in patients with acute liver failure(ALF) induced by traditional Chinese medicines(TCM) and by Western Medicines(WM).METHODS: The medical histories of patients who were diagnosed with drug-induced ALF(DALF)(n =96) after hospitalization in the 302 Military Hospital between January 2010 and December 2015 were retrospectively examined.RESULTS: Fifty-eight of the 96 DALF patients(60.4%) had a hepatocellular pattern of DALF, 16 patients(16.7%) had a cholestatic pattern, and 22 patients(22.9%) had a mixed pattern. DALF resolved in 24 patients(25.0%). Twenty-five patients(26.0%)developed chronic liver injury, 43 patients(44.8%)died, and 4 patients(4.2%) underwent liver transplantation. There were 42 ALF patients(43.8%) who received WM, and 32 ALF patients(33.3%) who received TCM. TCM-induced ALF patients had a higher average age [42.4 ± 18.4) vs(33.5 ± 17.9) years,P = 0.04] and higher creatinine and urine nitrogen levels [(155.2 ± 108.8) vs(97.5 ± 130.4) mmol/L, P =0.047;(9.1 ± 7.7) vs(4.3 ± 5.0) mmol/L, P = 0.002, respectively]. Patients with TCM-induced ALF exhibited an increased risk of renal injury [odds ratio(OR),3.75; 95% confidence interval(CI), 1.330-10.577].The 14 patients with TCM-induced ALF who died exhibited higher creatinine levels than the 18 patients with TCM-induced ALF patients who survived[(218.7 ± 111.6) vs(105.8 ± 78.4) mmol/L, P =0.002]. They were also more likely to exhibit ascites(85.7% vs 44.4%, P = 0.017) and hepatorenal syndrome(78.6% vs 22.2%, P = 0.002).CONCLUSION: TCM-induced ALF was more likely to be accompanied by renal injury than was WM-induced ALF, especially in TCM-induced ALF patients who died. | He Tingting Zhu Yun Wang Jiabo Gong Man Wang Ruilin Niu Ming Jing Jing Wang Lifu Wang Zhongxia Zhang Ning Bai Zhaofang Bai Yunfeng Li Yonggang Xiao Xiaohe | 2017 | Journal of Traditional Chinese Medicine2017，37，3： | 3 |
| 4 | Effects of renal sympathetic denervation on cardiac systolic function after myocardial infarction in rats显示文摘This study investigated the therapeutic effects of renal denervation on cardiac systolic function after myocardial infarction(MI) in rats and the mechanism involved.Fifty male SD rats were randomly assigned to the sham group(n = 15),the MI group(n = 20),and the MI plus renal denervation group(n = 15).MI was established through thoracotomic ligation of the anterior descending artery.Renal denervation was achieved by laparotomic stripping of the renal arterial adventitial sympathetic nerve,approximately 3 mm from the abdominal aorta.Left ventricular function and hemodynamics were measured several weeks following MI.The left ventricular systolic function of the MI group was significantly reduced and the systolic blood pressure(SBP) remarkably declined.In rats with MI treated with renal denervation,the left ventricular ejection fraction(EF),fractional shortening(FS) and SBP markedly improved compared with the MI group.However,heart rate and fibrosis decreased significantly.These findings suggest that renal denervation has therapeutic effects on post-MI cardiac dysfunction.These effects are associated with increased left ventricular ejection fraction(LVEF) and SBP,as well as reduced heart rate and fibrosis.This may represent a new approach to the treatment of post-MI remodeling and subsequent heart failure. | Jiqun Guo Zhongxia Zhou Zhenzhen Li Qian Liu Guoqing Zhu Qijun Shan | 2016 | The Journal of Biomedical Research2016，30，5： | 3 |
| 5 | Clinical Study on Ocular Trauma in Children显示文摘Purpose:To investigate the clinical characteristics of ocular trauma in children and put forward the major treatment and prevention of ocular trauma in children.Methods:To analyze the clinical data by 77 eyes in 77 cases of ocular trauma in children from April 1999 to February 20002.Resuts:The male and female were in the ratio of 2.21:1.Right eye ocular traumas were more than left ones.Ocular penetrating trauma was 83.12% and blunt trauma 12.99%.41 cases(53.25%)were injured by themselves while 33 cases by others.90.91% patients came from the countryside.Conclusion:The rate of blindness of children with ocular trauma could be reduced by prompt treatment.The study indicated that ocular trauma preventive pubicity should be faced in the countryside in order to improve the understanding of the severity of ocular trauma and treat it as a social problem. | Zicai Huang, Hongni Li, Yixia Huang, Zhongxia ZhouDepartment of Ophthalmology, Shantou Central Hospital, Shantou 515031, China | 2002 | 眼科学报2002，18，3： | 2 |
| 6 | E3泛素连接酶TRIM40通过靶向MDA5及RIG-I从而负向调控抗病毒天然免疫应答显示文摘文章简介维甲酸诱导基因I(RIG-I)样受体(RLR)家族成员RIG-I及MDA5在宿主识别病毒RNA过程中起到重要作用。RLR在识别外源RNA后,可通过一系列活化信号引起Ⅰ型干扰素及炎性细胞因子的表达,从而帮助机体迅速建立抗病毒状态。 | Chunyuan Zhao Mutian Jia Hui Song Zhongxia Yu Wenwen Wang Qi Li Lining Zhang 赵伟 曹雪涛 | 2018 | 科学新闻2018，0，4： | 1 |
| 7 | Vaginal protection and immunity after oral immunization of mice with a novel vaccine strain of Listeria monocytogenes expressing human immun- odeficiency virus type 1 gag 显示文摘 | Zhao Xinyan Zhang Manxin Li Zhongxia | 2006 | J Virol2006，80，18： | 1 |
| 8 | Pathogenicity and immunogenicity of a vaccine strain of Listeria monocytogenes that relies on a suicide plasmid to supply an essential gene product 显示文摘 | Zhao Xinyan Li Zhongxia Gu Baiyan | 2005 | In- fectImmun2005，73，9： | 1 |
| 9 | Daintain/AIF-1 promotes breast cancer cell migration by up-regulated TNF-α via activate p38 MAPK signaling pathway显示文摘 | Tao Li Zhiguo Feng Shaohui Jia Wei Wang Zhongxia Du Ning Chen Zhengwang Chen | 2012 | Breast Cancer Research and Treatment2012，，3： | 1 |
| 10 | A modified reversible data hiding in encrypted images using random diffusion and accurate pre- diction显示文摘 | Li Ming Xiao Di Peng Zhongxia | 2014 | ETRI Journal2014，36，2： | 1 |
| 11 | The investigation on aluminium alloys automobile wheel with low - titanium content produced by electrolysis 显示文摘 | Xie Jingpei Li Jiweng Liu Zhongxia | 2005 | Materials Science Forum2005，，： | 1 |
| 12 | Comparison of two optimization algorithms for estimating regional winter wheat yield by integrating MODIS leaf area index and World Food Studies Model显示文摘 | Liyan Tian Zhongxia Li Jianxi Huang | 2013 | Sensor Letters2013，11，67： | 1 |
| 13 | Effect of complex alloyong of Sc, Zr and Ti on the microstructure and mechanical properties of Al-5 Mg alloys 显示文摘 | LIU Zhongxia LI Zijiong WANG Mingxing | 2008 | Materials Science and Engineering A2008，，： | 1 |
| 14 | Novel intense pulsed light-photodynamic therapy strategy in the treatment of facial actinic keratoses concomitant with rosacea显示文摘Rosacea presents as transient or persistent erythema,papules,pustules,fAushing,and telangi-ectasia on the middle of the face,which has some clinical similarity with act inic keratosis(AK).These two conditions can coexist in the same patient.Dermoscopy and reflect ance confocal microscopy(RCM)could be useful methods for diagnosis and monitoring treatment efficacy.Novel intense pulsed light-photodynamic therapy(IPL-PDT)may have better tolerance and curative effect than traditional red-light 5-aminolevulinic acid photodynamic therapy(ALA-PDT).Herein,we present a case of facial AKs concomitant with rosacea where combination therapy of novel IPL-PDT and oral minocycline was effective in that AK lesions were eliminated and the patient's facial erythema and telangiectasia were significantly improved. | Shuzhan Shen Yajing Cao Jiandan Li Xiaojing Liu Zhongxia Zhou Xiuli Wang Peiru Wang | 2022 | Journal of Innovative Optical Health Sciences2022，15，4： | 0 |
| 15 | Reactive glia-to-GABAergic neuron reprogramming:a“golden touch”strategy to alleviate intractable seizures显示文摘This commentary highlights a research article published recently in Cell Stem Cell“Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy”.Generally,Lentini et al.reveal a strategy to fulfill in vivo glia-to-neuron reprogramming,which is a potential disease-modifying strategy for treatment of intractable seizures.Here,we describe exciting research advances in the treatment of intractable seizures based on this research article,summarizing its key findings,emphasizing its importance and providing further discussions.Further,issues worthy of further investigations are also postulated so that clinic translation can be better achieved. | Junzi Chen Zhongxia Li Liying Chen | 2022 | Acta Epileptologica2022，5，3： | 0 |
| 16 | Influence of the intelligent standing mobile robot on lower extremity physiology of complete spinal cord injury patients显示文摘Background:Spinal cord injury(SCI)remains a high rate of disability.In order to improve the quality of their lives,the application of robots in rehabilitation is increasing.However,few studies have assessed the applicability and the effect of robots in patients with complete injury.Objective:The current study aims to assess the efficacy of robots training on the lower extremity physiology in complete SCI patients.Methods:24 patients were recruited and randomly divided into experimental and control group.The two groups spent the same amount of time on regular training.Besides,a 1-h standing training twice daily was offered to both groups five days per week,for four weeks.The experimental group used robot for standing training,while the control group used standing frame.Before and after the experiment,muscle girth and bone mineral density(BMD)were measured as lower extremity physiology.Results:The experimental group showed increased muscle girth differences(left=0.08±0.40 cm,right=0.75±0.72 cm),while the control group showed decreased girth differences(left=-0.78±0.54 cm,right=-0.56±0.54 cm).The increases in the experimental group showed significant differences compared with the control group(left,P=0.0002;right,P=0.023).Both groups showed decreased BMD.The decreases in the experimental group were significantly smaller than those in the control group.Conclusions:Training with aid of robots combined with the regular rehabilitation treatment can benefit complete SCI patients,in aspect of postponing amyotrophy of lower extremities and reducing bone loss and osteoporosis. | Jibao Chen Zhongxia Jin Jiajia Yao Huifang Wang Yu Li Zengqiang Ouyang Yan Wang Wenxin Niu | 2020 | Medicine in Novel Technology and Devices2020，，3： | 0 |
| 17 | Adult-born neurons in critical period maintain hippocampal seizures via local aberrant excitatory circuits显示文摘Temporal lobe epilepsy(TLE),one common type of medically refractory epilepsy,is accompanied with altered adult-born dentate granule cells(abDGCs).However,the causal role of abDGCs in recurrent seizures of TLE is not fully understood.Here,taking advantage of optogenetic and chemogenetic tools to selectively manipulate abDGCs in a reversible manner. | Liying Chen Yingwei Xu Heming Cheng Zhongxia Li Nanxi Lai Menghan Li Yeping Ruan Yang Zheng Fan Fei Cenglin Xu Jiao Ma Shuang Wang Yan Gu Feng Han Zhong Chen Yi Wang | 2023 | Signal Transduction and Targeted Therapy2023，8，7： | 0 |
| 18 | Carrier balance and linear magnetoresistance in type-II Weyl semimetal WTe2显示文摘 | Xing-Chen Pan Yiming Pan Juan Jiang Huakun Zuo Huimei Liu Xuliang Chen Zhongxia Wei Shuai Zhang Zhihe Wang Xiangang Wan Zhaorong Yang Donglai Feng Zhengcai Xia Liang Li Fengqi Song Baigeng Wang Yuheng Zhang Guanghou Wang | 2017 | Frontiers of physics2017，12，3： | 0 |
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