|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development显示文摘Dear Editor,Previously,the Mendelian phe no types in huma n oocyte maturation arrest,fertilization failure and early embryonic arrest,are largely underestimated.In recent years,'missing'Men delian phe no types and genes in these processes are beginning to be uncovered by us and others(Huang et al.,2014;Alazami et al..2015;Feng et al.,2016;Xu et al.,2016;Chen et al.,2017;Sang et al.,2019).However,the genetic basis for majority of patients resulting from abnormalities in these phe no types remains to be elucidated. | Lin Zhao Songguo Xue Zhongyuan Yao Juanzi Shi Biaobang Chen Ling Wu Lihua Sun Yao Xu Zheng Yan Bin Li Xiaoyan Mao Jing Fu Zhihua Zhang Jian Mu Wenjing Wang Jing Du Shuai Liu Jie Dong Weijie Wang Qiaoli Li Lin He Li Jin Xiaozhen Liang Yanping Kuang Xiaoxi Sun Lei Wang Qing Sang | 2020 | Protein & Cell2020，11，12： | 10 |
| 2 | Advanced Electro-active Dry Adhesive Actuated by an Artificial Muscle Constructed from an Ionic Polymer Metal Composite Reinforced with Nitrogen-doped Carbon Nanocages显示文摘 | Qingsong He Xu Yang Zhongyuan Wang Jin Zhao Min Yu Zhen Hu Zhendong Dai | 2017 | Journal of Bionic Engineering2017，14，3： | 5 |
| 3 | Influence of meandering river sandstone architecture on waterflooding mechanisms: a case study of the M-I layer in the Kumkol Oilfield, Kazakhstan显示文摘In order to explore the influence of sandstone architecture on waterflooding mechanisms using the architecture method, and taking as an example the M-I layer of the Kumkol oilfield in the South Turgay Basin, Kazakhstan, we portrayed the architecture features of different types of sandstones and quantitatively characterized heterogeneities in a single sand body in meandering river facies. Based on the waterflooding characteristics of point bar sand and overbank sand according to waterflooded interpretation results in 367 wells and numerical simulation results of well groups, we finally analyzed the remaining oil potential of the meandering river sandstone and pointed out its development directions at the high water cut stage. The result shows that because lateral accretion shale beds are developed inside single sand bodies, the point bar sand is a semi-connected body. The overbank sand is thin sandstone with poor connectivity, small area and fast lateral changes. The heterogeneity of the overbank sand is stronger than the point bar sand. The sandstone architectures control the waterflooding characteristics. In meandering river sandstones, the bottom of the point bar sand is strongly waterflooded, while the top of the point bar sand and most of the overbank sand are only weakly waterflooded or unflooded. The thickness percentage of unflooded zone and weakly waterflooded zone in point bar sand is 40%, and the remaining oil in its top part is the main direction for future development. | Wang Jincai Zhao Lun Zhang Xiangzhong Tian Zhongyuan Chen Xi He Ling | 2014 | Petroleum Science2014，11，1： | 5 |
| 4 | Swelling and thermal properties of porous PNIPAM/PEG hydrogels prepared by radiation polymerization显示文摘In this study,a series of porous intelligent hydrogels were synthesized by radiation exhibiting the lower critical solution temperature(LCST) and fast response involving a combination of A’-isopropyl acrylamideas monomer, polyethylene glycol(PEG) as pore-forming agent and N,N-methylene-bis-acrylamide as crosslinking agent.The hydrogels were analyzed by Fourier transform infrared spectroscopy,and the influence of radiation doses on their swelling and thermal behaviors were studied.Their surface morphologies were examined by scanning electron microscopy.The results showed that PEG molecules only acted as pore-forming agent in the cross-linked polymerization.Their swelling ratios reduced with increasing radiation doses.The LCST was around 37℃,and varied little with the radiation doses.The frozen water content of PNIPAM/PEG6000 hydrogel reduced with increasing the radiation dose,and was greater than that of PN1PAM hydrogel at 15 kGy.Hydrogel macropores were prepared by PEG agent,and the hydrogels without PEG had a dense surface.The porous hydrogels are expected to be applied in the field of artificial intelligence material. | LI Zhihui LIU Wentao LI Zhongyuan YANG Mingcheng GAO Xujing CUI Haitao HE Suqin ZHU Chengshen | 2013 | Nuclear Science and Techniques2013，24，2： | 3 |
| 5 | A single-cell transcriptome of mesenchymal stromal cells to fabricate bioactive hydroxyapatite materials for bone regeneration显示文摘The osteogenic microenvironment of bone-repairing materials plays a key role in accelerating bone regeneration but remains incompletely defined,which significantly limits the application of such bioactive materials.Here,the transcriptional landscapes of different osteogenic microenvironments,including three-dimensional(3D)hydroxyapatite(HA)scaffolds and osteogenic medium(OM),for mesenchymal stromal cells(MSCs)in vitro were mapped at single-cell resolution.Our findings suggested that an osteogenic process reminiscent of endochondral ossification occurred in HA scaffolds through sequential activation of osteogenic-related signaling pathways,along with inflammation and angiogenesis,but inhibition of adipogenesis and fibrosis.Moreover,we revealed the mechanism during OM-mediated osteogenesis involves the ZBTB16 and WNT signaling pathways.Heterogeneity of MSCs was also demonstrated.In vitro ossification of LRRC75A+MSCs was shown to have better utilization of WNT-related ossification process,and PCDH10+MSCs with superiority in hydroxyapatite-related osteogenic process.These findings provided further understanding of the cellular activity modulated by OM conditions and HA scaffolds,providing new insights for the improvement of osteogenic biomaterials.This atlas provides a blueprint for research on MSC heterogeneity and the osteogenic microenvironment of HA scaffolds and a database reference for the application of bioactive materials for bone regeneration. | Peng Guo Xizhe Liu Penghui Zhang Zhongyuan He Zhen Li Mauro Alini RGeoff Richards Sibylle Grad Martin J.Stoddart Guangqian Zhou Xuenong Zou Danny Chan Wei Tian Dafu Chen Manman Gao Zhiyu Zhou Shaoyu Liu | 2022 | Bioactive Materials2022，7，3： | 3 |
| 6 | Chemical synthesis and characterization of manganese oxide coated Ni particles显示文摘Nanosized Ni particles with an average diameter of about 8 nm were prepared by reducing of NiCl 2 with sodium borohydride (NaBH 4 ) in aqueous solution. By moderate annealing in protective atmosphere, the composite grew up to be 15-20 nm particles. Both of the as-prepared and annealed Ni particles were coated by a layer of manganese oxide via decomposition reaction in aqueous KMnO4 solution. Hysteresis loops of as-prepared samples show a large increase in the magnetization with decreasing temperature and an unsaturated component at high magnetic field. In contrast, the ferromagnetic characteristics of annealed one are much stronger with large magnetization and coercivity. The thermomagnetic curves verified the coexistence of ferromagnetic Ni and antiferromangetic Mn oxide phases. But there exists no exchange bias behavior in the samples, even though the interface structure between the ferromagnetic Ni core and the antiferromagnetic manganese oxides has been distinctly formed. The absence of exchange bias probably originates from the weak ferromagnetic characteristic of Ni cores. | AN Jing XU LiHong HE Jun ZHAO DongLiang LIU ZhongYuan | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，8： | 2 |
| 7 | Effect of cyclic mechanical loading on immunoinflammatory microenvironment in biofabricating hydroxyapatite scaffold for bone regeneration显示文摘It has been proven that the mechanical microenvironment can impact the differentiation of mesenchymal stem cells(MSCs).However,the effect of mechanical stimuli in biofabricating hydroxyapatite scaffolds on the inflammatory response of MSCs remains unclear.This study aimed to investigate the effect of mechanical loading on the inflammatory response of MSCs seeded on scaffolds.Cyclic mechanical loading was applied to biofabricate the cell-scaffold composite for 15 min/day over 7,14,or 21 days.At the predetermined time points,culture supernatant was collected for inflammatory mediator detection,and gene expression was analyzed by qRT-PCR.The results showed that the expression of inflammatory mediators(IL1B and IL8)was downregulated(p<0.05)and the expression of ALP(p<0.01)and COL1A1(p<0.05)was upregulated under mechanical loading.The cell-scaffold composites biofabricated with or without mechanical loading were freeze-dried to prepare extracellular matrix-based scaffolds(ECM-based scaffolds).Murine macrophages were seeded on the ECM-based scaffolds to evaluate their polarization.The ECM-based scaffolds that were biofabricated with mechanical loading before freeze-drying enhanced the expression of M2 polarization-related biomarkers(Arginase 1 and Mrc1,p<0.05)of macrophages in vitro and increased bone volume/total volume ratio in vivo.Overall,these findings demonstrated that mechanical loading could dually modulate the inflammatory responses and osteogenic differentiation of MSCs.Besides,the ECM-based scaffolds that were biofabricated with mechanical loading before freeze-drying facilitated the M2 polarization of macrophages in vitro and bone regeneration in vivo.Mechanical loading may be a promising biofabrication strategy for bone biomaterials. | Penghui Zhang Xizhe Liu Peng Guo Xianlong Li Zhongyuan He Zhen Li Martin J.Stoddart Sibylle Grad Wei Tian Dafu Chen Xuenong Zou Zhiyu Zhou Shaoyu Liu | 2021 | Bioactive Materials2021，6，10： | 2 |
| 8 | Drought-induced proline is mainly synthesized in leaves and transported to roots in watermelon under water deficit显示文摘Proline accumulation has been shown to occur in plants in response to various environmental stresses.Although proline metabolismrelated genes have been functionally characterized,the inter-organ transport of proline in stressed plants remains unclear.In this study,free proline was detected with significant accumulations in the roots,stems,and leaves of watermelon drought-tolerant germplasm M08 and drought-susceptible line Y34 under drought stress.Expression profiling and enzyme activity measurements revealed that ClP5CS1 gene,rather than its paralog ClP5CS2,mainly contributes to the proline synthesis in leaves via the Glu pathway.Additionally,over-expression of the ClP5CS genes significantly enhanced the drought tolerance of transgenic Arabidopsis lines.Furthermore,we confirmed that proline is mainly synthesized in leaves and transported to roots in watermelon under drought stress.Transcriptome and expression analyses revealed that the genes involved in proline metabolism exhibited different expression levels.Specifically,ClP5CS1 was upregulated in leaves and roots,while ClP5CS2 was downregulated under drought stress.Also,415 and 362 differently expressed TFs were identified in roots and leaves,respectively,with the majority upregulated in the former.Ultimately,a model for proline metabolism was proposed.The findings of this study provided new insights into the biosynthesis,transport,and regulatory mechanism of drought-induced proline in plants. | Zhongyuan Wang Yongchao Yang Vivek Yadav Wei Zhao Yaping He Xian Zhang Chunhua Wei | 2022 | Horticultural Plant Journal2022，8，5： | 2 |
| 9 | Structural and thermoelectric characterizations of high pressure sintered nanocrystalline Bi 2 Te 3 bulks显示文摘 | Fengrong Yu Bo Xu Jianjun Zhang Dongli Yu Julong He Zhongyuan Liu Yongjun Tian | 2012 | Materials Research Bulletin2012，，6： | 1 |
| 10 | Capillary microchannel-based microreactors with highly durable ZnO/TiO 2 nanorod arrays for rapid, high efficiency and continuous-flow photocatalysis显示文摘 | Zhongyuan He Yaogang Li Qinghong Zhang Hongzhi Wang | 2009 | Applied Catalysis B Environmental2009，，3： | 1 |
| 11 | Distribution-tunable growth of ZnO nanorods on the inner walls of microcapillaries from reverse micelle deriving seed patterns显示文摘 | Zhongyuan He Qinghong Zhang Yaogang Li Hongzhi Wang | 2009 | Materials Chemistry and Physics2009，，1： | 1 |
| 12 | Thermoelectric properties of n-type CoSb 3 fabricated with high pressure sintering显示文摘 | Jianjun Zhang Bo Xu Fengrong Yu Dongli Yu Zhongyuan Liu Julong He Yongjun Tian | 2010 | Journal of Alloys and Compounds2010，，2： | 1 |
| 13 | Capillary microchannel-based microreactors with highly durable ZnO/TiO 2 nanorod arrays for rapid, high efficiency and continuous-flow photocatalysis显示文摘 | Zhongyuan He Yaogang Li Qinghong Zhang Hongzhi Wang | 2009 | Applied Catalysis B Environmental2009，，3： | 1 |
| 14 | Distribution-tunable growth of ZnO nanorods on the inner walls of microcapillaries from reverse micelle deriving seed patterns显示文摘 | Zhongyuan He Qinghong Zhang Yaogang Li Hongzhi Wang | 2009 | Materials Chemistry and Physics2009，，1： | 1 |
| 15 | Vegetation Restoration Monitoring in Yingxiu Landslide Area after the 2008 Wenchuan Earthquake显示文摘A total of more than 50000 landslides has occurred in Sichuan province since the'5·12'Wenchuan earthquake,resulting in serious damage to the surface vegetation in southwestern China.In this study,we select Yingxiu,the epicenter of Wenchuan earthquake,as the experimental area.The vegetation coverage information of the experimental area is extracted from the remote sensing images collected in the year of 2005,2011 and 2013,respectively.The surface vegetation coverage in different periods is analyzed,and the vegetation recovery rate of the whole area is calculated.The experimental results show that in the first three years after the earthquake,the speed of vegetation restoration is slow,and the vegetation coverage rate is less than 20%better than 0.241,while in 2013,the vegetation coverage increases significantly. | HE Jing ZHANG Keke LIU Xiuju LIU Gang ZHAO Xuqiang XIE Zhongyuan LU Heng | 2020 | Earthquake Research in China2020，34，1： | 1 |
| 16 | Performance Analysis for Multimedia Communication Systems with a Multilayer Queuing Network Model显示文摘Software performance evaluation in multimedia communication systems is typically formulated into a multi-layered client-server queuing network(MLCSQN) problem. However, the existing analytical methods to MLCSQN model cannot provide satisfactory solution in terms of accuracy, convergence and consideration of interlocking effects. To this end, this paper proposes a heuristic solving method for MLCSQN model to boost the performance prediction of distributed multimedia software systems. The core concept of this method is referred to as the basic model, which can be further decomposed into two sub-models: client sub-model and server sub-model. The client sub-model calculates think time for server sub-model, and the server sub-model calculates waiting time for client sub-model. Using a breadthfirst traversal from leaf nodes to the root node and vice versa, the basic model is then adapted to MLCSQN, with net sub-models iteratively resolved. Similarly, the interlocking problem is effectively addressed with the help of the basic model. This analytical solver enjoys advantages of fast convergence, independence on specific average value analysis(MVA) methods and eliminating interlocking effects.Numerical experimental results on accuracy and computation efficiency verify its superiority over anchors. | Xuehua Tang Zhongyuan Wang Xiaojun Li Zhen Han Zheng He Youming Fu | 2018 | China Communications2018，15，8： | 1 |
| 17 | Self-regulation in chemical and bio-engineering materials for intelligent systems显示文摘 | Zhongyuan Huang Kewei Lei Dan He Yanbin Xu Jacob Williams Liu Hu Macy McNeil Juan M. Ruso Zhen Liu Zhanhu Guo Zhe Wang | 2018 | CAAI Transactions on Intelligence Technology2018，3，1： | 0 |
| 18 | STUDY ON THE PERFORMANCE AND MECHANISM OF ADSORPTING RHENIUM BY USING NEUTRAL PHOSPHOROUS-BASED LEVEXTREL RESIN Ⅱ. CL-P350-KReO_4-HCl System显示文摘In this paper study on the property and mechanism of adsorpting rhenium from aqueous hydrochloric acid by using methyl phosphorous acid dimythyl heptyl ester levextrel resin(CL-P350) is reported.The effects of time,acidity,concentration of rhenium,and temperature on the adsorption of rhenium were investigated. The mechanism of adsorpting rhenium was discussed by chemical analytic and IR method,and dynamic adscrption and elution were studied.Experimental results show that the adsorption equilibration is reached in 4 min,the distribution coefficient(D) of Re(Ⅶ)increases with increase of concentration of HCl and reaches maximum 3.0-4.0moL/L HCl.ReO4^- is taken up by ion association mechanism and can be described by Langmuir equation of the equilibrium state.The thermodynamic parameters in the adsorption process of ReO4^- have been determined to be:ΔH=-29KJ/moL,ΔG=-25KJ/moL and ΔS=-13.5J/moL respectively.The saturation adsorption capacity of rhenium is 19.2mg/g when the solution containing 0.372g/L Re and 3.0mol/L HCl was passed through the resin column.The recovery percentage of rhenium is 98.4% while distilled water was used as an eluent. | HE Huanjie, ZHAO Deqi, ZHAN Shixin, FENG Jianzhong, WANG Zhanhe (Laboratory, Zhongyuan Petroleum School, Puyang 457001, China) | 1993 | Chinese Journal of Reactive Polymers1993，2，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员