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| 1 | Vitamin B2 functionalized iron oxide nanozymes for mouth ulcer healing显示文摘Mouth ulcer is associated with inflammation and high risk of bacterial infection, which aggravates the patient's condition.Currently, there is no effective treatment for mouth ulcer. Herein, we report that vitamin-modified iron oxide nanoparticles improve the healing of mouth ulcer through anti-inflammation and antibacterial activities. We discovered that vitamin B2(VB2)modified iron oxide nanoparticles performed enhanced peroxidase-like, catalase-like, and superoxide dismutase(SOD)-like activities, acting as typical iron oxide nanozymes(IONzymes) with triad activities. In particular, VB2 modification significantly improved the SOD-like activity, thus providing a reactive oxygen species(ROS)-scavenging ability. Cellular antioxidant experiments showed that vitamin B2 modified IONzymes(VB2-IONzymes) protect human oral keratinocytes(HOK) and BALB/3 T3 cells from hydrogen peroxide(H2O2), and these cells have high biocompatibility to eukaryotic cells. In addition, VB2-IONzymes exerted an antibacterial activity against Streptococcus mutans, Staphylococcus aureus, and Escherichia coli. Importantly, VB2-IONzymes accelerated the recovery of mouth ulcer and reduced the local secretion of inflammatory factors in mouse ulcer model via ROS scavenging and antibacterial activity. Taken together, our work demonstrates that vitamin B2 modification endows iron oxide nanoparticles with enhanced enzyme-like activities and VB2-IONzymes may be a promising reagent in the treatment of mouth ulcer because of their intrinsic anti-inflammation and antibacterial capabilities. | Yunhao Gu Yixin Huang Zhiyue Qiu Zhuobin Xu Dandan Li Lei Chen Jing Jiang Lizeng Gao | 2020 | Science China(Life Sciences)2020，63，1： | 10 |
| 2 | Azomethine-H as a Highly Selective Fluorescent Probe for Fe^3+ Detection in 100% Aqueous Solution and Its Application in Living Cell Imaging显示文摘 | YU Fang QIN Liyuan SHANG Zhuobin DONG Zhenming WANG Yu JIN Weijun | 2015 | Chemical Research in Chinese Universities2015，31，6： | 2 |
| 3 | Separation and determination of Rutin and Quercetin in the flowers of Sophora Japonica L by capillary electrophoresis with electrochemical detection显示文摘 | Li Xiangjun Zhang Yuping Yuan Zhuobin | 2002 | Chromatographia2002，55，： | 1 |
| 4 | Determination of active components in rhubarb and study of their hydrophobicity by mi- cellar electrokinetic chromatography 显示文摘 | SHANG Xiaoyu YUAN Zhuobin | 2003 | Bioorg Med Chem Lett2003，13，4： | 1 |
| 5 | Research on Coordination Mechanism in Construction Project Organization显示文摘The construction process of modern project is distributed across teams, departments, or systems, each of which is corresponding to a particular project unit. Conflicts often occur in construction project organization because of the improper coordination amongbetween these project units. The primary reason for coordination puzzle in project organization is generally the diversification of culture and technology. In order to enhance the organization’s performance efficiency, good and effective coordination mechanism aimed at diversification of culture and technology is needed. The relationship amongbetween parties and project units is defined and expressed through contract, so construction project organization usually relies on various contracts to deal with its cooperative partner relationship. However, the contractual mode is a defensive method which is more prone to conflicts than the conglomerate of diversification, especially evaluated from the aspects of culture and value. By culture integration—a more flexible way to make up the shortage of contractual mode, a harmonious atmosphere in which organization members can exert their potential ability can be created to help project administrators mitigate organization conflicts and achieve the common goals of project organization. Based on arbitration theory, moreover, this paper puts forward a combined coordination mechanism-hierarchical coordination and nonhierarchical coordination—to resolve the conflicts resulted from diversification of technology. The introduction of intelligent agents system has the advantage of a more systematic and organizational method in reality without causing unnecessary emotional and the behavioural side effects is an effective instrument to utilize this coordination mechanism and realizes its established goals. | Chen Shouke Cheng Hu Wei Zhuobin | 2006 | 工程科学(英文版)2006，4，3： | 1 |
| 6 | Study on the electrochemical behavior of dopamine with poly ( sulfosalicylic acid)modified glassy carbon electrode 显示文摘 | Hong Zhao Yuzhong Zhang Zhuobin Yuan | 2001 | Anal Chim Acta2001，441，1： | 1 |
| 7 | Electrochemical behaviour of norepinephrine at poly ( 2,4,6 - trimethylpyridine ) modified glassy carbon electrode 显示文摘 | Zhao Hong Zhang Yuzhong Yuan Zhuobin | 2002 | Electroanalysis2002，14，5： | 1 |
| 8 | Interleukin-17 augments tumor necrosis factor-α-induced granulocyte and granulocyte/macrophage colony-stimulating factor release from human colonic myofibroblasts显示文摘 | Akira Andoh Hirofumi Yasui Osamu Inatomi Zhuobin Zhang Yasuyuki Deguchi Kazunori Hata Yoshio Araki Tomoyuki Tsujikawa Katsuyuki Kitoh Shokei Kim-Mitsuyama Atsushi Takayanagi Nobuyoshi Shimizu Yoshihide Fujiyama | 2005 | Journal of Gastroenterology2005，，8： | 1 |
| 9 | Poly (isonicotinic acid) modified glassy carbon norepinephrine显示文摘 | Zhao Hong Zhang Yuzhong Yuan Zhuobin | 2002 | Analy Chim Acta2002，454，1： | 1 |
| 10 | Conductivity and Oxidation Behavior of Fe-16Cr Alloy as Solid Oxide Fuel Cell Interconnect Under Long-Stability and Thermal Cycles显示文摘Conductivity and oxidation behavior of Fe-16Cr alloy were investigated under long-term stability operation at 750℃and thermal cycles from room temperature to 750℃.The results showed that the area specific resistance(ASR)of Fe-16Cr alloy increased over time and reached about 56.29 mΩcm~(2)after 40,000 h of long-term stability operation at 750℃by theoretical calculation.The ASR of Fe-16Cr remained about 11 mΩcm~(2)after 52 thermal cycles from room temperature to750℃.The analysis of structure showed that the oxidized phase on the surface of Fe-16Cr was mainly composed of Cr_(2)O_3and Fe Cr_(2)O_(4)spinel phase under long-term stability operation at 750℃.While the Cr_(2)O_(3)phase was mainly observed on the surface of Fe-16Cr alloy after 52 thermal cycles,the oxidation rates of Fe-16Cr alloy were 0.0142μm h~(-1)and 0.06μm cycle~(-1)under long-term stability operation and under thermal cycle,respectively.The property of Fe-16Cr alloy with 2.6 mm thickness met the lifespan requirement of interconnect for solid oxide fuel cell(SOFC)stacks.The Cr element all diff used onto oxidation surface,indicating that it was necessary to spray a coating on the surface to avoid poisoning cell cathode of SOFCs.Two 2-cell stacks were assembled and tested to verify the properties of Fe-16Cr alloy as SOFC interconnect under long-term stability operation and thermal cycle condition. | Jianwu Zhou Qiangfeng Chen Junkang Sang Rongmin Wu Zhuobin Li Wanbing Guan | 2021 | Acta Metallurgica Sinica(English Letters)2021，34，5： | 1 |
| 11 | Supramolecular inclusion com-plex formation and application ofβ-cy-clodertrin with heteroanthra-cene ring cationic dyes显示文摘 | Yuan Zhuobin Zhu Min Han Shaubo | 1999 | Analytica Chimica ACTA1999，389，13： | 1 |
| 12 | Alizarin Complexone as a highly selective ratiometric fluorescent probe for Al 3+ detection in semi-aqueous solution显示文摘 | Yu Wang Ling Jie Hou Yan-Bo Wu Li Li Shi Zhuobin Shang Wei Jun Jin | 2014 | Journal of Photochemistry & Photobiology, A: Chemistry2014，，： | 1 |
| 13 | Determination of rutin and forsythin in fruit of Forsythia suspensa(Thunb) Vahl by capillary electrophoresis - electrochemical detection 显示文摘 | Li Xiangjun Zhang Yuping Yuan Zhuobin | 2002 | Chromatographia2002，56，34： | 1 |
| 14 | Determination of six components in Rhubarb by cyelodextrin - modified mieellar eleetrokinetic chromatography using a mixed micellar system of sodium eholate and sodium taurocholate显示文摘 | Shang Xiaoyu Yuan Zhuobin | 2002 | Anal Chim Acta2002，456，： | 1 |
| 15 | Butyrate blocks interferon-γ-inducible protein-10 release in human intestinal subepithelial myofibroblasts显示文摘 | Osamu Inatomi Akira Andoh Ken-ichi Kitamura Hirofumi Yasui Zhuobin Zhang Yoshihide Fujiyama | 2005 | Journal of Gastroenterology2005，，5： | 1 |
| 16 | Determination of baicalin, chlorogenic acid and forsythin in Chinese medicinal preparation by capillary electrophoresis显示文摘 | Xiangjun Li Yuping Zhang Zhuobin Yuan | 2002 | Chromatographia (-)2002，，7： | 1 |
| 17 | Selective determination of dopamine in the presence of ascorbic acid at a multi-wall carbon nanotube-poly(3,5-dihydroxy benzoic acid) film modified electrode显示文摘 | Xia Zhou Na Zheng Shurong Hou Xiangjun Li Zhuobin Yuan | 2010 | Journal of Electroanalytical Chemistry2010，，1： | 1 |
| 18 | Interaction offl-cyclodextrin-capped CdSe quantum dots with inorganic anions and cations显示文摘 | Shang Zhuobin Hu Shuang | 2011 | The Journal of Biological Luminescence2011，26，1： | 1 |
| 19 | A New Biphenylcarbonitrile Based Fluorescent Sensor for Zn2+ Ions and Application in Living Ceils显示文摘 | FENG Jia SHAO Xiuqing SHANG Zhuobin CHAO Jianbin WANG Yu JIN Weijun | 2017 | Chemical Research in Chinese Universities2017，33，5： | 0 |
| 20 | Effects of combined substitution of Dy and Mo or Si on the crystal structures and magnetic properties of Nd_(1-y)Dy_yFe_(11-x)TiM_x(M=Mo,Si) compounds显示文摘A series of Nd1-yDyyFe11-xTiMx(M=Mo,Si) alloys have been prepared by arc melting and studied by X-ray diffraction and neutron diffraction.All samples are found to crystallize in the ThMn12-type structure.The lattice parameters a and c and unit cell volume V of Nd0.5Dy0.5Fe11-xTiMox alloys increase linearly with increasing content of Mo(x),while the lattice parameters a and c and unit cell volume V of Nd0.5Dy0.5Fe11-xTiSix alloys decrease linearly with increasing content of Si(x).In NdyDy1-yFe11-xTiMx(M=Mo,Si) compounds,Ti and Mo atoms preferentially occupy the 8i sites and Si atoms preferentially occupy the 8j and 8f sites.Magnetic measurements show that the substitution of Fe by either Mo or Si leads to a decrease in the Curie temperature. | LI XiangJun,ZHENG Na,HU ZhongBo & YUAN ZhuoBin College of Chemistry and Chemical Engineering,Graduate University of Chinese Academy of Sciences,Beijing 100049,China | 2009 | Science China Chemistry2009，52，8： | 0 |
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