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| 1 | Co-Channel Interference Suppression Techniques for Full Duplex Cellular System显示文摘Co-frequency and co-time full duplex(CCFD) is a promising technique for improving spectral efficiency in next generation wireless communication systems. However, for the applications of CCFD in a cellular network, severe co-channel interference is an essential problem. Specifically, there are two significant interferences, i.e., inter-terminal interference(ITI) and inter-cell interference(ICI), which lead to an obvious performance degradation. In this paper, two techniques are proposed for suppressing the ITI and ICI in a CCFD cellular system, respectively. The first technique is obtained by modeling the three-node CCFD system as the Z-channel. After deriving the sum-capacity of the Z-channel, a sum-capacity-achieving scheme based on successive interference cancellation(SIC) is proposed. The second technique is designed by combining the fractional frequency reuse scheme with CCFD. The performance gains of the proposed two techniques in terms of signalto-interference plus noise ratio(SINR) and sumcapacity are analyzed. Simulation results show that the proposed scheme can achieve significant interference suppression performance and higher system capacity, especially for cell edge users. | XIN Yongchao MA Meng ZHAO Zijun JIAO Bingli | 2015 | China Communications2015，12，S1： | 3 |
| 2 | New opportunities and challenges of natural products research:When target identification meets single-cell multiomics显示文摘Natural products, and especially the active ingredients found in traditional Chinese medicine(TCM), have a thousand-year-long history of clinical use and a strong theoretical basis in TCM. As such,traditional remedies provide shortcuts for the development of original new drugs in China, and increasing numbers of natural products are showing great therapeutic potential in various diseases. This paper reviews the molecular mechanisms of action of natural products from different sources used in the treatment of inflammatory diseases and cancer, introduces the methods and newly emerging technologies used to identify and validate the targets of natural active ingredients, enumerates the expansive list of TCM used to treat inflammatory diseases and cancer, and summarizes the patterns of action of emerging technologies such as single-cell multiomics, network pharmacology, and artificial intelligence in the pharmacological studies of natural products to provide insights for the development of innovative natural product-based drugs. Our hope is that we can make use of advances in target identification and singlecell multiomics to obtain a deeper understanding of actions of mechanisms of natural products that will allow innovation and revitalization of TCM and its swift industrialization and internationalization. | Yuyu Zhu Zijun Ouyang Haojie Du Meijing Wang Jiaojiao Wang Haiyan Sun Lingdong Kong Qiang Xu Hongyue Ma Yang Sun | 2022 | Acta Pharmaceutica Sinica B2022，12，11： | 3 |
| 3 | Polydopamine-modified collagen sponge scaffold as a novel dermal regeneration template with sustained release of platelet-rich plasma to accelerate skin repair:A one-step strategy显示文摘Although employed to release growth factors(GFs)for regenerative medicine,platelet-rich plasma(PRP)has been hindered by issues like burst effect.Based on collagen sponge scaffolds(CSSs)modified with polydopamine(pDA),a novel dermal regeneration template(DRT)was designed.However,whether it could efficiently deliver PRP and even foster wound healing remained unclear.In this work,after PRP was prepared and pDA-modified CSSs(pDA-CSSs)were fabricated,microscopic observation,GFs release assay and in-vitro biological evaluations of pDA-CSSs with PRP(pDA-CSS@PRP)were performed,followed by BALA-C/nu mice full-thickness skin defects implanted with pDA-CSS@PRP covered by grafted skins(termed as a One-step strategy).As a result,scanning electron microscope demonstrated more immobilized platelets on pDA-CSS′surface with GFs’controlled release via enzyme-linked immunosorbent assay,compared with CSSs.In line with enhanced in-vitro proliferation,adhesion and migration of keratinocytes&endothelial cells,pDA-CSS@PRP were histologically revealed to accelerate wound healing with less scar via rapid angiogenesis,arrangement of more mature collagen,guiding cells to spread,etc.In conclusion,pDA-CSSs have potential to serve as a novel DRT capable of delivering PRP,which may foster full-thickness skin defect healing by means of a One-step strategy. | Zijun Zheng Minxiong Li Pengwei Shi Yanbin Gao Jun Ma Yuchen Li Lei Huang Zhangfeifan Yang Lei Yang | 2021 | Bioactive Materials2021，6，8： | 2 |
| 4 | Extraction Process and Content Determination of Caffeic Acid in Laggera alata from Different Production Areas of Guangxi显示文摘[Objectives] To establish a method for determining the content of Laggera alata( D. Don) Sch. Bip. Ex Oliv. using caffeic acid the target component,and to compare the content of caffeic acid in the medicinal materials of L. alata in different production areas of Guangxi.[Methods]The content was determined by Inertsil~ODS-3 chromatographic column C_(18)( 4. 60 mm × 250 mm,5 μm,mobile phase: acetonitrile-0. 1% phosphoric acid( 22∶ 78),detection wavelength: 320 nm,flow rate: 1. 0 m L/min,column temperature: 30℃,and injection volume: 10 μL. [Results] The caffeic acid showed a good linear relationship in the range of injection volume of 0. 025 92-0. 259 2 μg( R =0. 999 5). The average recovery rate was 98. 33%( RSD = 1. 85%). L. alata in different production areas of Guangxi contained the caffeic acid,and there was a great difference in the caffeic acid. L. alata in Baise had the highest content of caffeic acid,while that in Guilin had the lowest content of caffeic acid. [Conclusions]This method can accurately determine the content of caffeic acid and is expected provide a scientific basis for the development and utilization of herbal medicine L. alata. | Jiangcun WEI Yong CHEN Zujie QIN Jiabao MA Shengbin CHEN Zuliang QUE Jinzhou LI Zijun CHEN | 2018 | Medicinal Plant2018，9，4： | 1 |
| 5 | Senescence in chronic wounds and potential targeted therapies显示文摘Chronic wounds(e.g.diabetic wounds,pressure wounds,vascular ulcers,etc.)do not usually heal in a timely and orderly manner but rather last for years and may lead to irreversible adverse events,resulting in a substantial financial burden for patients and society.Recently,a large amount of evidence has proven that cellular senescence has a crucial influence on chronic nonhealing wounds.As a defensive mechanism,cell senescence is a manner of cell-cycle arrest with increased secretory phenotype to resist death,preventing cells from stress-induced damage in cancer and noncancer diseases.A growing amount of research has advanced the perception of cell senescence in various chronic wounds and focuses on pathological and physiological processes and therapies targeting senescent cells.However,previous reviews have failed to sum up novel understandings of senescence in chronic wounds and emerging strategies targeting senescence.Herein,we discuss the characteristics and mechanisms of cellular senescence and the link between senescence and chronic wounds as well as some novel antisenescence strategies targeting other diseases that may be applied for chronic wounds. | Xuerong Wei Minxiong Li Zijun Zheng Jun Ma Yanbin Gao Lianglong Chen Yujie Peng Shengxiang Yu Lei Yang | 2022 | Burns & Trauma2022，10，1： | 1 |
| 6 | Sediment budget and riverbed deformation in the uppermost part of the lower Yangtze River, China显示文摘The Yangtze River(YR), similar to most large rivers in the world, has experienced significant changes in its depositional environment due to anthropogenic disturbances and climatic influences in recent decades. However, knowledge of how the river channel and bed deformation respond to these changes in the uppermost part of the lower YR, a 200-km-long branched channel, is limited. In the current study,historical bathymetric data collected from 1992 to 2013 and high-resolution multibeam echo sounder(MBES) data obtained from 2015 to 2016 were analyzed to address the changes in the depositional environment. The results indicate that the whole riverbed in the Hukou to Datong reach(HDR) has been scouring over the past two decades and this trend is expected to continue in the future due to decreasing sediment supply from the upper watershed. The amount of net erosion from the HDR during 1992-2013approximately accounted for 7.2% of total sediment load in the Yangtze River(5.02 billion metric tons at Datong). The evolution of the riverbed is trending towards stabilization even though the patterns of erosion and/or deposition in the HDR have dramatically changed in the last two decades. The part of the channel from the upper 100 km to Datong was found to be a sensitive reach that first showed erosion from 1992 to 2003 and showed deposition during 2003-2008, and then mild erosion during 2008-2013in response to environmental changes. Thus, the findings indicate that riverine channel deformation in response to anthropogenic disturbance and climate influence is dynamic in different reaches, and this finding has both scientific and practical significance in terms of understanding channel stability and its response to external stressors. | Shuwei Zheng Huanlong Luo Jiayue Zhang Heqin Cheng Zijun Li Yugai Ma Shuaihu Wu Enfeng Liu | 2022 | International Journal of Sediment Research2022，37，4： | 0 |
| 7 | Advances in magnetic resonance imaging contrast agents for glioblastoma-targeting theranostics显示文摘Glioblastoma(GBM)is the most aggressive malignant brain tumour,with a median survival of 3 months without treatment and 15 months with treatment.Early GBM diagnosis can significantly improve patient survival due to early treatment and management procedures.Magnetic resonance imaging(MRI)using contrast agents is the preferred method for the preoperative detection of GBM tumours.However,commercially available clinical contrast agents do not accurately distinguish between GBM,surrounding normal tissue and other cancer types due to their limited ability to cross the blood-brain barrier,their low relaxivity and their potential toxicity.New GBM-specific contrast agents are urgently needed to overcome the limitations of current contrast agents.Recent advances in nanotechnology have produced alternative GBM-targeting contrast agents.The surfaces of nanoparticles(NPs)can be modified with multimodal contrast imaging agents and ligands that can specifically enhance the accumulation of NPs at GBM sites.Using advanced imaging technology,multimodal NP-based contrast agents have been used to obtain accurate GBM diagnoses in addition to an increased amount of clinical diagnostic information.NPs can also serve as drug delivery systems for GBM treatments.This review focuses on the research progress for GBMtargeting MRI contrast agents as well as MRI-guided GBM therapy. | Zijun Wu Lixiong Dai Ke Tang Yiqi Ma Bin Song Yanrong Zhang Jinxing Li Su Lui Qiyong Gong Min Wu | 2021 | Regenerative Biomaterials2021，8，6： | 0 |
| 8 | Understanding the drivers of woody plant diversity in urban parks in a snow climate city of China显示文摘Urban parks are an important part of urban ecosystems and play an important role in biodiversity conservation.However,it is still unclear how park characteristics aff ect plant diversity which could hinder the conservation of urban biodiversity due to the ineff ective design of urban parks.The diversity of woody plants in 33 parks of Changchun,China,was measured with plot measurements and linked with urban park characteristics(e.g.,size and age of the park)to uncover the relationship between them.The results show that urban woody plant species were abundant,with 98 species belonging to 51 genera and 26 families in the snow climate city of Changchun.The variation in woody plant diversity was largely explained by internal patch characteristics(e.g.,size,age,shape),and external factors surrounding the park(e.g.,land use type and socioeconomic level)accounted for only 16.0%in our study.For internal patch characteristics,older urban parks with larger areas demonstrated a richer level of plant diversity and increased nonlinearly with increasing park area.The threshold size signifi cantly aff ecting plant diversity variation was approximately 30 ha.Plant diversity had positive linear relationships with the ages of urban parks,supporting the legacy eff ect.In addition,woody plant diversity nonlinearly decreased with increasing park shape index,which suggested that the plant diversity could also be increased by optimizing the park shape.Regarding the external factors surrounding parks,the spatial distribution of woody plant diversity varied greatly from the urban center to the suburbs.House prices around the park had positive linear relationships with woody plant diversity in parks,supporting the luxury eff ect.However,building and road proportions,and green space proportion had no relationship with plant diversity in parks.This study can provide a robust reference for enriching plant diversity in urban parks,thus improving the development of urban sustainable cities. | Zijun Ma Peng Zhang Nanlin Hu Guodong Wang Yulin Dong Yujie Guo Chengcong Wang Yao Fu Zhibin Ren | 2023 | Journal of Forestry Research2023，34，4： | 0 |
| 9 | Distribution and invasion of Spartina alterniflora within the Jiaozhou Bay monitored by remote sensing image显示文摘Spartina alterniflora as an alien invasive plant,poses a serious threat to the ecological functions of the coastal wetland of the Jiaozhou Bay.As of 2019,the distribution area of S.alterniflora in the Jiaozhou Bay has reached more than 500 hm^(2).For this reason,combined with field surveys,remote sensing monitoring of the invasion S.alterniflora in the Jiaozhou Bay has been carried out.To accurately identify S.alterniflora within the Jiaozhou Bay coastal wetland,we used a new method which is an implement of deep convolutional neural network,and by which we got a higher accuracy than the traditional method.Based on distribution of S.alterniflora extracted by the proposed method,the temporal and spatial distribution characteristics of S.alterniflora were analyzed.And then combined with environmental factors,the invasion mechanism of S.alterniflora in the Jiaozhou Bay was analyzed in detail.From the monitoring results,it can be seen that S.alterniflora in Jiaozhou Bay is mainly distributed in the beaches near the Yanghe River Estuary and its southern side,the Dagu River Estuary and the Nügukou.Spartina alterniflora first broke out near the Yanghe River Estuary and gradually spread to the tidal flats near the Nügukou.The Dagu River Estuary is dominated by S.anglica,whose area has not changed much over the years,and a small amount of S.alterniflora has invaded later. | Jianbu Wang Zhaoyang Lin Yuanqing Ma Guangbo Ren Zijun Xu Xiukai Song Yi Ma Andong Wang Yajie Zhao | 2022 | Acta Oceanologica Sinica2022，41，6： | 0 |
| 10 | Optical engineering of infrared PbS CQD photovoltaic cells for wireless optical power transfer systems显示文摘Infrared photovoltaic cells(IRPCs)have attracted considerable attention for potential applications in wireless optical power transfer(WOPT)systems.As an efcient fber-integrated WOPT system typically uses a 1550 nm laser beam,it is essential to tune the peak conversion efciency of IRPCs to this wavelength.However,IRPCs based on lead sulfde(PbS)colloidal quantum dots(CQDs)with an excitonic peak of 1550 nm exhibit low short circuit current(Jsc)due to insufcient absorption under monochromatic light illumination.Here,we propose comprehensive optical engineering to optimize the device structure of IRPCs based on PbS CQDs,for 1550 nm WOPT systems.The absorption by the device is enhanced by improving the transmittance of tin-doped indium oxide(ITO)in the infrared region and by utilizing the optical resonance efect in the device.Therefore,the optimized device exhibited a high short circuit current density of 37.65 mA/cm^(2)under 1 sun(AM 1.5G)solar illumination and 11.91 mA/cm^(2)under 1550 nm illumination 17.3 mW/cm^(2).Furthermore,the champion device achieved a record high power conversion efciency(PCE)of 7.17%under 1 sun illumination and 10.29%under 1550 nm illumination.The PbS CQDs IRPCs under 1550 nm illumination can even light up a liquid crystal display(LCD),demonstrating application prospects in the future. | Mengqiong Zhu Yuanbo Zhang Shuaicheng Lu Zijun Wang Junbing Zhou Wenkai Ma Ruinan Zhu Guanyuan Chen Jianbing Zhang Liang Gao Jiancan Yu Pingqi Gao Jiang Tang | 2023 | Frontiers of Optoelectronics2023，16，2： | 0 |
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