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| 1 | High-peak-power temporally shaped nanosecond fiber laser immune to SPM-induced spectral broadening显示文摘High-peak-power transform-limited narrow-linewidth nanosecond all-fiber lasers are desired in a range of applications.However,their linewidths will be broadened by self-phase modulation(SPM).We propose a novel concept that generates transform-limited laser pulses by temporally shaping the pulse seed.The impact of the pulse shape on SPM-induced spectral broadening was studied numerically and experimentally.It was found theoretically that the square-shape pulsed laser is immune to SPM-induced spectral broadening.Based on this principle,we built a high-peak-power,linearly polarized,square-shape nanosecond all-fiber laser in a master oscillator power amplifier(MOPA)configuration.Stimulated Brillouin scattering(SBS)limited peak powers of 4.02 kW,5.06 kW,6.52 kW and 9.30 kW were obtained at pulse widths of 8 ns,7 ns,6 ns and 5 ns.Thanks to the square-shape pulsed seed,the linewidths at maximum peak power remained at 129.5 MHz,137.6 MHz,156.2 MHz and 200.1 MHz,respectively,close to the transform-limited values of110.8 MHz,126.6 MHz,147.7 MHz and 177.3 MHz. | Rongtao Su Pengfei Ma Pu Zhou Zilun Chen Xiaolin Wang Yanxing Ma Jian Wu Xiaojun Xu | 2019 | High Power Laser Science and Engineering2019，7，2： | 4 |
| 2 | An additive dripping technique using diphenyl ether for tuning perovskite crystallization for high-efficiency solar cells显示文摘 | Di Huang Tenghooi Goh Yifan Zheng Zilun Qin Jiao Zhao Suling Zhao Zheng Xu Andre D. Taylor | 2018 | Nano Research2018，11，5： | 3 |
| 3 | Endovascular repair of a type B aortic dissection with a ventricular septal defect occluder显示文摘 | Guangqi Chang Huishen Wang Wei Chen Chen Yao Zilun Li Shenming Wang | 2010 | Journal of Vascular Surgery2010，，6： | 1 |
| 4 | Loss mechanism of all-fiber cascaded side pumping combiner显示文摘Compared with end pumping fiber combiner, one of the advantages for side pumping combiner is the unlimited pumping points, which means multi-point or cascaded side pumping can be realized. However, the loss mechanism of the cascaded structure is rarely discussed. In this paper, we present the numerical and experimental investigation about the loss mechanism of a two-stage-cascaded side pumping combiner based on tapered-fused technique. The influence of loss mechanism on the coupling efficiency and thermal load of the fiber coating is analyzed according to simulations and experiments with different tapering ratios for the first stage. Based on the analysis, a cascaded component with total pump coupling efficiency of 96.4% handling a pump power of 1088 W is achieved by employing 1018 nm fiber laser as the pump source. Future work to further improve the performance of a cascaded side pumping combiner is discussed and prospected. | Chengmin Lei Zilun Chen Yanran Gu1,Hu Xiao Jing Hou | 2018 | High Power Laser Science and Engineering2018，6，4： | 1 |
| 5 | Theoretical investigation of core mode cut-off condition for tapered multicore fiber显示文摘Core mode cutoff is a useful concept not only for a tapered single-core fiber(SCF) but also for a tapered multicore fiber(MCF) to realize cladding mode transmission. In this paper, cut-off conditions of either core mode for tapered SCFs or supermodes for MCFs are theoretically investigated. Rigorous analytical formulas are derived for the modes of SCF by a three-layer waveguide model, and an approximation formula of the cut-off condition is given for the LP01 mode. The supermodes of MCFs are analyzed by the coupling mode theory, and the cut-off condition is calculated by a numerical method. Simulation results show that the in-phase supermode of MCFs has a similar cut-off condition with that of SCF. Based on this property, a convenient approximate formula is given to estimate the cut-off condition of the in-phase supermode for tapered MCFs. | Xuanfeng Zhou Zilun Chen Hang Zhou Jing Hou | 2015 | Photonics Research2015，3，5： | 1 |
| 6 | Mutual injection- locking and coherent combining of two individual fiber lasers 显示文摘 | Chen Zilun Hou Jing Zhou Pu | 2008 | IEEE Journal of Quantum Electronics2008，44，6： | 1 |
| 7 | Mutual injection locking and coherent combining of three individual fiber lasers 显示文摘 | Chen Zilun Hou Jing Zhou Pu | 2008 | Optics Communications2008，，： | 1 |
| 8 | Cascaded PCF tapers for flat broadband supercontinuum generation 显示文摘 | CHEN Haihuan CHEN Zilun ZHOU Xuanfeng | 2012 | Chinese OpticsLetters(S1671-7694)2012，10，12： | 1 |
| 9 | Numerical study of supercontinuum generation in photonic crytal fibers with two zero dispersion wavelengths显示文摘 | Chen Haihuan Chen Zilun | | 0，，2： | 1 |
| 10 | Mutual injection locking and coherent combining of three individual fiber lasers显示文摘 | Chen Zilun Hou Jing Zhou Pu | 2009 | Optics Communications2009，282，1： | 1 |
| 11 | Dual-wavelength-pumped supercontinuum generation in an all-fiber device显示文摘 | Xiong Chunle Chen Zilun Wadsworth W J | 2009 | Journal of Lightwave Technology2009，27，11： | 1 |
| 12 | The transcriptome of circulating cells indicates potential biomarkers and therapeutic targets in the course of hypertension-related myocardial infarction显示文摘Hypertension(HT)is the most common public-health challenge andshows a high inci-dence around the world.Cardiovascular diseases are the leadingcause of mortality and morbidity among the elderly(age>65 years)in the UnitedStates.Now,there is widespread acceptanceof the causal link between HT and acute myocardial infarction(MI).This is the first data-mining study to identify co-expressed differentially expressed genes(Co-DEGs)between HT and MI(rela-tive to nommal control)and to uncover potential biomarkers and therapeutic targets of HT-related MI.In thismanuscript,HT-specfcDEGs andMl-specific DEGs and dffretially expressed microRNAs(DE-miRNAs)were identifhed in Gene Expression Omnibus(GEO)datasets GSE24752,GSE60993,GSE62646,and GSE24548 after data consolidation and batch correction.Subse-quently,enichmentin Gene Ontology(GO)terms and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathways as well as protein-protein interaction networks were identified,and single-gene gene set enrichment analysis was performed to determine the affected biological cate-gories and networks.Cross-matching of the results on cCo-DE-miRNAs and predicted miRNAs tar-geting the Co-DEGs wasconducted and discussed as well.We found thatMYC and HIST1H2BO may be associatedwith HT,whereas FCGR 1A,FYN,KLRD1,KLRB1,and FOLR3 may be implicated in MI.Moreover,Co-DEGs FOLR3 and NFE2 with predicted miRNAs and DE-miRNAs,especially miR-7 and miR-548,may be significantly associated and show huge potential as a new set of novel bio-markers and important molecular targets in the course of HT-related MI. | Zilun Wei Yining Yang Qiaoling Li Yong Yin Zhonghai Wei Wenfeng Zhang Dan Mu Jie Ni Xuan Sun Biao Xu | 2021 | Genes & Diseases2021，8，4： | 1 |
| 13 | miR-505-5p alleviates acute rejection of liver transplantation by inhibiting Myd88 and inducing M2 polarizationof Kupffer cells显示文摘The occurrence of acute rejection after liver transplantation seriously impairs the prognosis of patients.miRNA is involved in many physiological and pathological processes of the body,but the mechanism of miRNA action in liver transplantation is not completely clear.In this study,we discuss the role of miR-505-5p in acute rejection after liver transplantation and its putative regulating mechanism.We construct an allogeneic rat liver transplantation model,observe the morphological and pathological changes in liver tissue,detect the expression levels of Myd88,miR-505-5p,IL-10 and TNF-α,and confirm that Myd88 is one of the direct targets of miR-505.The effects of miR-505-5p on the Myd88/TRAF6/NF-κB and MAPK pathways are detected both in vitro and in vivo,and the standard markers of Kupffer cell M1/M2 polarization are also detected.The results of qRT-PCR experiments show that miR-505-5p has a downward trend in rats with acute rejection.Western blot analysis reveals that over-expression of miR-505-5p induces the reduction of NF-κB and MAPK pathways both in vitro and in vivo.The role of miR-505-5p in alleviating acute rejection after transplantation may be accomplished by inducing M2-type polarization of Kupffer cells.In conclusion,we find that miR-505-5p alleviates acute rejection of liver transplantation by inducing M2 polarization of macrophages via the Myd88/TRAF6 axis,which suggests a potential strategy based on miRNAs in the follow-up treatment of liver transplantation. | Hao Chai Zilun Lei Yanyao Liu Junhua Gong Zhenrui Cao Zuotian Huang Hang Yang Zhongjun Wu | 2022 | Acta Biochimica et Biophysica Sinica2022，54，8： | 0 |
| 14 | COVID-19 induces new-onset insulin resistance and lipid metabolic dysregulation via regulation of secreted metabolic factors显示文摘Abnormal glucose and lipid metabolism in COVID-19 patients were recently reported with unclear mechanism.In this study,we retrospectively investigated a cohort of COVID-19 patients without pre-existing metabolic-related diseases,and found new-onset in suli n resista nee,hyperglycemia,and decreased HDL-C in these patie nts.Mecha nistically,SARS-CoV-2 infecti on in creased the expression of RE1-silencing transcription factor(REST),which modulated the expression of secreted metabolic factors including myeloperoxidase,apelin,and myostatin at the transcriptional level,resulting in the perturbation of glucose and lipid metabolism.Furthermore,several lipids,including(±)5-HETE,(±)12-HETE,propionic acid,and isobutyric acid were identified as the potential biomarkers of COVID-19-induced metabolic dysregulation,especially in insulin resistance.Taken together,our study revealed insulin resistance as the direct cause of hyperglycemia upon COVID-19,and further illustrated the underlying mechanisms,providing potential therapeutic targets for COVID-19-induced metabolic complications. | Xi He Chenshu Liu Jiangyun Peng Zilun Li Fang Li Jian Wang Ao Hu Meixiu Peng Kan Huang Dongxiao Fan Na Li Fuchun Zhang Weiping Cai Xinghua Tan Zhongwei Hu Xilong Deng Yueping Li Xiaoneng Mo Linghua Li Yaling Shi Li Yang Yuanyuan Zhu Yanrong Wu Huichao Liang Baolin Liao Wenxin Hong Ruiying He Jiaojiao Li Pengle Guo Youguang Zhuo Lingzhai Zhao Fengyu Hu Wenxue Li Wei Zhu Zefeng Zhang Zeling Guo Wei Zhang Xiqiang Hong Wei kang Cai Lei Gu Ziming Du Yang Zhang Jin Xu Tao Zuo Kai Deng Li Yan Xinwen Chen Sifan Chen Chunliang Lei | 2022 | Signal Transduction and Targeted Therapy2022，7，1： | 0 |
| 15 | Comparative Study on Physical Activity in Diabetic and Non-Diabetic Individuals and Influential Factors—China,2020–2021显示文摘Summary What is already known about this topic?The majority of Chinese patients with diabetes failed to achieve the level of physical activity recommended by clinical guidelines.What is added by this report?The prevalence of low-level physical activity was found to be greater in individuals diagnosed with diabetes.It was observed that patients with a protracted duration of diabetes demonstrated a propensity to participate in lower levels of physical activity compared to those with a shorter disease trajectory.The likelihood of engaging in low-level physical activity associated with diabetes was higher in rural inhabitants,those with medium-tier education,employed individuals,and individuals who had longer sleep durations.What are the implications for public health practice?Developing strategies and interventions to encourage greater involvement of Chinese diabetic patients in physical activity is essential.However,these strategies must take population characteristics into account. | Aolin Li Jun Lyu Yuanyuan Chen Zilun Shao Dianjianyi Sun Canqing Yu Liming Li | 2023 | China CDC weekly2023，5，45： | 0 |
| 16 | Excitation and propagation of surface plasmon polaritons on a non-structured surface with a permittivity gradient显示文摘Accompanied by the rise of plasmonic materials beyond those based on noble metals and the development of advanced materials processing techniques,it is important to understand the plasmonic behavior of materials with large-scale inhomogeneity(such as gradient permittivity materials)because they cannot be modeled simply as scatterers.In this paper,we theoretically analyze the excitation and propagation of surface plasmon polaritons(SPPs)on a planar interface between a homogeneous dielectric and a material with a gradient of negative permittivity.We demonstrate the following:(i)free-space propagating waves and surface waves can be coupled by a gradient negative-permittivity material and(ii)the coupling can be enhanced if the material permittivity variation is suitably designed.This theory is then verified by numerical simulations.A direct application of this theory,‘rainbow trapping’,is also proposed,considering a realistic design based on doped indium antimonide.This theory may lead to various applications,such as ultracompact spectroscopy and dynamically controllable generation of SPPs. | Xi Wang Yang Deng Qitong Li Yijing Huang Zilun Gong Kyle B Tom Jie Yao | 2016 | Light(Science & Applications)2016，5，1： | 0 |
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