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34篇 您的检索式:作者名="Zipeng Li"
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1Down-regulation of the let-7i facilitates gastric cancer invasion and metastasis by targeting COL1A1显示文摘Dear Editor,Globally,gastric cancer is the most common malignant tumor and the second highest contributor to cancer deaths after lung cancer(Murray et al.,2012).Despite improved success with treatment of early stage gastric cancer(Fuse et al.,2016),the five-year survival rate of advanced staged gastric cancer patients is still low.The aggressive growth characteristics of the tumor and metastasis are key factors responsible for poor overall survival in these patients(Ozkan et al.,2005).Therefore,investigation of the molecular mechanisms that underlie the aggressive behavior of gastric cancers,and identification of potential target genes for therapeutic interventions,is a key imperative.Yue Shi Zipeng Duan Xun Zhang Xiaotian Zhang Guoqing Wang Fan Li 2019Protein & Cell2019,10,2:9
2Analysis of variation trends and causes of aerosol optical depth in Shaanxi Province using MODIS data显示文摘The temporal and spatial variations and causes of aerosol optical depth(AOD)in Shaanxi Province were investigated based on the Moderate Resolution Imaging Spectroradiometer(MODIS)derived aerosol data for the period of March 2000–February 2012.The results showed that the distribution of aerosol was largely affected by topography and local economic activities.Heavy aerosol loading and increasing tendency in AOD was observed in Guanzhong,Hanzhong and Ankang basin,while a reverse tendency was revealed in most other regions.The spatial distribution of aerosol Angstrom wavelength exponent was predominantly related to vegetation coverage in Shaanxi.Airborne dust from ground is an important source of coarse mode aerosols.Vegetation improvement indicated by an increase in normalized difference vegetation index(NDVI)and a reduction in dust weather led to a gradual decrease in coarse mode AOD to the north of Qinling Mountains in Shaanxi,while anthropogenic activities led to an increase in fine mode AOD in other areas except those covered by forests.The main aerosol type gradually shifted to the urban industrial type in Shaanxi.DONG ZiPeng YU Xing LI XingMin DAI Jin 2013Chinese Science Bulletin2013,58,35:8
3Vertical distribution of aerosol optical properties based on aircraft measurements over the Loess Plateau in China显示文摘Vertical distributions of aerosol optical properties based on aircraft measurements over the Loess Plateau were measured for the first time during a summertime aircraft campaign, 2013 in Shanxi, China. Data from four flights were analyzed. The vertical distributions of aerosol optical properties including aerosol scattering coefficients(σsc), absorption coefficients(σab),Angstr?m exponent(α), single scattering albedo(ω), backscattering ratio(βsc), aerosol mass scattering proficiency(Q sc) and aerosol surface scattering proficiency(Q sc′) were obtained. The mean statistical values of σsc were 77.45 Mm-1(at 450 nm), 50.72 Mm-1(at 550 nm), and32.02 Mm-1(at 700 nm). The mean value of σab was 7.62 Mm-1(at 550 nm). The mean values ofα, βsc and ω were 1.93, 0.15, and 0.91, respectively. Aerosol concentration decreased with altitude. Most effective diameters(ED) of aerosols were less than 0.8 μm. The vertical profiles of σsc,, α, βsc, Q sc and Q sc′ showed that the aerosol scattering properties at lower levels contributed the most to the total aerosol radiative forcing. Both α and βsc had relatively large values, suggesting that most aerosols in the observational region were small particles. The mean values of σsc, α, βsc, Q sc, Q sc′, σab and ω at different height ranges showed that most of the parameters decreased with altitude. The forty-eight hour backward trajectories of air masses during the observation days indicated that the majority of aerosols in the lower level contributed the most to the total aerosol loading, and most of these particles originated from local or regional pollution emissions.Junxia Li Xingang Liu Liang Yuan Yan Yin Zhanqing Li Peiren Li Gang Ren Lijun Jin Runjun Li Zipeng Dong Yiyu Li Junmei Yang 2015Journal of Environmental Sciences2015,27,8:6
4In situ development of highly concave and compositionconfined PtNi octahedra with high oxygen reduction reaction activity and durability显示文摘有为催化氧减小反应(ORR ) 的唯一的结构的 PtNi 金属 nanocrystals 的控制综合体吸引了大兴趣。这里,我们报导单个水晶的 PtNi octahedra 的一步舞合成与在里面开发 situ 高度为 ORR 是最佳的凹面特征和自我限制的作文。揭示的详细研究充满磅的播种、随后的 Pt/Ni 合作减小,和 PtNi 融合导致了一致单个水晶的 PtNi octahedra,并且 Ni 富有的表面蚀刻的 Ni 方面分离和氧的联合导致了凹度并且限制了 Ni 内容。凹面 PtNi nanocrystals 以两个比商业地可得到的 Pt/C 催化剂展出了高得多的 ORR 性能特定的活动(高 29.1 倍) 并且集体活动(高 12.9 倍) 在 0.9 V (对可逆的氢电极(RHE )) 。没有凹度,表演也比 PtNi octahedra 的高,证实更高的活动是仔细与它的形态学有关。而且,凹面 octahedra 也由于不稳定的地点的钝化在 ORR (在在 0.6 和 1.1 V 对 RHE 之间的 10,000 个周期以后仍然是的 93% 集体活动) 展出了显著稳定性。Enbo Zhu Yongjia Li Chin-Yi Chiu Xiaoqing Huang Mufan Li Zipeng Zhao Yuan Liu Xiangfeng Duan Yu Huang 2016Nano Research2016,9,1:4
5ETCM v2.0:An update with comprehensive resource and rich annotations for traditional Chinese medicine显示文摘Existing traditional Chinese medicine(TCM)-related databases are still insufficient in data standardization,integrity and precision,and need to be updated urgently.Herein,an Encyclopedia of Traditional Chinese Medicine version 2.0(ETCM v2.0,http://gffzz3ff3e9d9e9f64aa3h6u5oqq69bvn06ffn.ffgz.tsg.suse.edu.cn/ETCM2/front/#/)was constructed as the latest curated database hosting 48,442 TCM formulas recorded by ancient Chinese medical books,9872 Chinese patent drugs,2079 Chinese medicinal materials and 38,298 ingredients.To facilitate the mechanistic research and new drug discovery,we improved the target identification method based on a two-dimensional ligand similarity search module,which provides the confirmed and/or potential targets of each ingredient,as well as their binding activities.Importantly,five TCM formulas/Chinese patent drugs/herbs/ingredients with the highest Jaccard similarity scores to the submitted drugs are offered in ETCM v2.0,which may be of significance to identify prescriptions/herbs/ingredients with similar clinical efficacy,to summarize the rules of prescription use,and to find alternative drugs for endangered Chinese medicinal materials.Moreover,ETCM v2.0 provides an enhanced Java Script-based network visualization tool for creating,modifying and exploring multi-scale biological networks.ETCM v2.0 may be a major data warehouse for the quality marker identification of TCMs,the TCM-derived drug discovery and repurposing,and the pharmacological mechanism investigation of TCMs against various human diseases.Yanqiong Zhang Xin Li Yulong Shi Tong Chen Zhijian Xu Ping Wang Meng Yu Wenjia Chen Bing Li Zhiwei Jing Hong Jiang Lu Fu Wenjing Gao Yanhua Jiang Xia Du Zipeng Gong Weiliang Zhu Hongjun Yang Haiyu Xu 2023Acta Pharmaceutica Sinica B2023,13,6:3
6Ultrathin wavy Rh nanowires as highly effective electrocatalysts for methanol oxidation reaction with ultrahigh ECSA显示文摘Direct methanol fuel cells (DMFCs) have received tremendous research interests because of the facile storage of liquid methanol vs.hydrogen.However,the DMFC today is severely plagued by the poor kinetics and rather high overpotential in methanol oxidation reaction (MOR).Here we report the investigation of the ultrathin Rh wavy nanowires as a highly effective MOR electrocatalyst.We show that ultrathin wavy Rh nanowires can be robustly synthesized with 2-3 nm diameters.Electrochemical studies show a current peak at the potential of 0.61 V vs.reversible hydrogen electrode (RHE),considerably lower than that of Pt based catalysts (~ 0.8-0.9 V vs.RHE).Importantly,with ultrathin diameters and favorable charge transport,the Rh nanowires catalysts exhibit an ultrahigh electrochemically active surface area determined from CO-stripping (ECSAco) of 144.2 m2/g,far exceeding that of the commercial Rh black samples (20 m2/g).Together,the Rh nanowire catalysts deliver a mass activity of 722 mA/mg at 0.61 V,considerably higher than many previously reported electrocatalysts at the same potential.The chronoamperometry studies also demonstrate good stability and CO-tolerance compared with the Rh black control sample,making ultrathin Rh wavy nanowires an attractive electrocatalyst for MOR.Xiaoyang Fu Zipeng Zhao Chengzhang Wan Yiliu Wang Zheng Fan Frank Song Bocheng Cao Mufan Li Wang Xue Yu Huang Xiangfeng Duan 2019Nano Research2019,12,1:3
7Wavelet transform based on inner product in fault diagnosis of rotating machinery: A review 显示文摘Jinglong Chen Zipeng Li Jun Pan 2016Mechanical Systems and Signal Processing2016,70,:1
8The Design and Simulation Test of Wireless Antenna Protection Network显示文摘Chen Zipeng Dai Yawen Li Peng 2013Journal of Physics: Conference Series2013,418,:1
9A Mixed-integer SDP Solution to Distributionally Robust Unit Commitment with Second Order Moment Constraints显示文摘A power system unit commitment(UC)problem considering uncertainties of renewable energy sources is investigated in this paper,through a distributionally robust optimization approach.We assume that the first and second order moments of stochastic parameters can be inferred from historical data,and then employed to model the set of probability distributions.The resulting problem is a two-stage distributionally robust unit commitment with second order moment constraints,and it can be recast as a mixed-integer semidefinite programming(MI-SDP)with finite constraints.The solution algorithm of the problem comprises solving a series of relaxed MI-SDPs and a subroutine of feasibility checking and vertex generation.Based on the verification of strong duality of the semidefinite programming(SDP)problems,we propose a cutting plane algorithm for solving the MI-SDPs;we also introduce an SDP relaxation for the feasibility checking problem,which is an intractable biconvex optimization.Experimental results on the IEEE 6-bus system are presented,showing that without any tuning of parameters,the real-time operation cost of distributionally robust UC method outperforms those of deterministic UC and two-stage robust UC methods in general,and our method also enjoys higher reliability of dispatch operation.Xiaodong Zheng Haoyong Chen Yan Xu Zhengmao Li Zhenjia Lin Zipeng Liang 2020CSEE Journal of Power and Energy Systems2020,6,2:1
10High temperature ceramic thermal insulation material显示文摘Flexible and lightweight thermal insulation materials with hierarchical microstructures are ubiquitous in thermal management and protection systems.Ceramic aerogels promise high-temperature thermal insulation but lack mechanical robustness,while the fibrous materials with excellent mechanical elasticity display modest thermal insulation.Here we describe flexible hierarchical superhydrophobic ceramic insulation nanocomposites through the densified architectured hierarchical nanostructures,radiative insulation coating,and interfacial cross-linking among composites.The lightweight flexible ceramic nanocomposites exhibit a density of 0.13 g/cm^(3),high-temperature fire resistance with thermal conductivity of 0.024 W/(m·K),and super-hydrophobicity with the water contact angle of 152°.The mechanical robustness and high-temperature thermal insulation of ceramic nanocomposites,together with its soundproof performance,shed light on the low-cost flexible insulation materials manufacturing with scalability for high-temperature thermal insulation applications under high mechanical loading conditions.Lu An Jason N.Armstrong Yong Hu Yulong Huang Zheng Li Donghui Zhao Jesse Sokolow Zipeng Guo Chi Zhou Shenqiang Ren 2022Nano Research2022,15,7:1
11Eddy-resolving Simulation of CAS-LICOM3 for Phase 2 of the Ocean Model Intercomparison Project显示文摘A 61-year(1958–2018)global eddy-resolving dataset for phase 2 of the Ocean Model Intercomparison Project has been produced by the version 3 of Chinese Academy of Science,the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics/Institute of Atmospheric Physics(LASG/IAP)Climate system Ocean Model(CAS-LICOM3).The monthly and a part of the surface daily data in this study can be accessed on the Earth System Grid Federation(ESGF)node.Besides the details of the model and experiments,the evolutions and spatial patterns of large-scale and mesoscale features are also presented.The mesoscale features are reproduced well in the high-resolution simulation,as the mesoscale activities can contribute up to 50%of the total SST variability in eddy-rich regions.Also,the large-scale circulations are remarkably improved compared with the low-resolution simulation,such as the climatological annual mean SST(the RMSE is reduced from 0.59°C to 0.47°C,globally)and the evolution of Atlantic Meridional Overturning Circulation.The preliminary evaluation also indicates that there are systematic biases in the salinity,the separation location of the western boundary currents,and the magnitude of eddy kinetic energy.All these biases are worthy of further investigation.Yiwen LI Hailong LIU Mengrong DING Pengfei LIN Zipeng YU Yongqiang YU Yao MENG Yunlong LI Xiaodong JIAN Jinrong JIANG Kangjun CHEN Qian YANG Yaqi WANG Bowen ZHAO Jilin WEI Jinfeng MA Weipeng ZHENG and Pengfei WANG 2020Advances in Atmospheric Sciences2020,37,10:1
12FGOALS-g3 Model Datasets for CMIP6 Flux-Anomaly-Forced Model Intercomparison Project显示文摘The Flux-Anomaly-Forced Model Intercomparison Project(FAFMIP)is an endorsed Model Intercomparison Project in phase 6 of the Coupled Model Intercomparison Project(CMIP6).The goal of FAFMIP is to investigate the spread in the atmosphere–ocean general circulation model projections of ocean climate change forced by increased CO2,including the uncertainties in the simulations of ocean heat uptake,global mean sea level rise due to ocean thermal expansion and dynamic sea level change due to ocean circulation and density changes.The FAFMIP experiments have already been conducted with the Flexible Global Ocean–Atmosphere–Land System Model,gridpoint version 3.0(FGOALS-g3).The model datasets have been submitted to the Earth System Grid Federation(ESGF)node.Here,the details of the experiments,the output variables and some baseline results are presented.Compared with the preliminary results of other models,the evolutions of global mean variables can be reproduced well by FGOALS-g3.The simulations of spatial patterns are also consistent with those of other models in most regions except the North Atlantic and the Southern Ocean,indicating large uncertainties in the regional sea level projections of these two regions.Yaqi WANG Zipeng YU Pengfei LIN Hailong LIU Jiangbo JIN Lijuan LI Yanli TANG Li DONG Kangjun CHEN Yiwen LI Qian YANG Mengrong DING Yao MENG Bowen ZHAO Jilin WEI Jinfeng MA and Zhikuo SUN 2020Advances in Atmospheric Sciences2020,37,10:1
13Characterizing fatigue crack closure by ntunerical analysis显示文摘Yazhi Li Jing He Zipeng Zhang 2008Advanced Materials Research2008,3337,:1
14The Brassicaceae-specific secreted peptides,STMPs,function in plant growth and pathogen defense显示文摘Low molecular weight secreted peptides have recently been shown to affect multiple aspects of plant growth,development,and defense responses.Here,we performed stepwise BLAST filtering to identify unannotated peptides from the Arabidopsis thaliana protein database and uncovered a novel secreted peptide family,secreted transmembrane peptides(STMPs).These low molecular weight peptides,which consist of an N-terminal signal peptide and a transmembrane domain,were primarily localized to extracellular compartments but were also detected in the endomembrane system of the secretory pathway,including the endoplasmic reticulum and Golgi.Comprehensive bioinformatics analysis identified 10 STMP family members that are specific to the Brassicaceae family.Brassicaceae plants showed dramatically inhibited root growth uponexposure to chemically synthesized STMP1 and STMP2.Arabidopsis overexpressing STMP1,2,4,6,or 10 exhibited severely arrested growth,suggesting that STMPs are involved in regulating plant growth and development.In addition,in vitro bioassays demonstrated that STMP1,STMP2,and STMP10 have antibacterial effects against Pseudomonas syringae pv.tomato DC3000,Ralstonia solanacearum,Bacillus subtilis,and Agrobacterium tumefaciens,demonstrating that STMPs are antimicrobial peptides.These findings suggest that STMP family members play important roles in various developmental events and pathogen defense responses in Brassicaceae plants.Zipeng Yu Yang Xu Lifei Zhu Lei Zhang Lin Liu Di Zhang Dandan Li Changai Wu Jinguang Huang Guodong Yang Kang Yan Shizhong Zhang Chengchao Zheng 2020Journal of Integrative Plant Biology2020,62,4:1
15Possible v_(τ) Mass Measurement Study at Beijing Spectrometer显示文摘This paper investigates the feasibility of theτneutrino mass measurement at the Beijing Spectrometer(BES).Theτevent selection criteria have been obtained by studying the earlier BES Ds data.Based on a total integrated luminosity of 35pb-1 at√s=4.03 GeV,an upper limit on mvT,of approximately 25 MeV appears possible for the T→K+K-πvτ,decay channel.CHEN Shaomin YAN Wuguang LI Jin ZHENG Zipeng 1994Chinese Physics Letters1994,11,5:0
16From'step-up'to'step-jump':a leap-forward intervention for infected necrotizing pancreatitis显示文摘Acute pancreatitis(AP)can vary widely in its severity,from being clinically self-limiting to a rapidly fatal course.[1]Necrotizing pancreatitis(NP)is the most serious form and is associated with a poor prognosis;the mortality rate is approximately 15%,or up to 30%for cases of infected necrotizing pancreatitis(INP),which often progresses to sepsis and multiple organ failure,the major cause of death and severe complications.[2]The approach to the management of INP has significantly changed during the last 20 years and continues to evolve with the accumulation of experience,new techniques,and research data.Major surgical intervention and debridement were once the mainstay of therapy for patients with symptomatic necrotic foci,but a minimally invasive approach that focuses on percutaneous and/or endoscopic drainage or debridement is now favored.[2]The'step-up'approach,which involves minimally invasive techniques,represents a new paradigm for the treatment of patients with INP,and open pancreatic debridement is now considered to be the final step in the treatment of NP.[2]Dongya Huang Qiang Li Zipeng Lu Kuirong Jiang Junli Wu Wentao Gao Bin Xiao Yi Miao 2022Chinese Medical Journal2022,,3:0
17Responses of arid plant species diversity and composition to environmental factors显示文摘An oasis is a unique natural landscape in arid and semi-arid areas,significant for regulating regional microclimates and hydrological processes in deserts.However,little is known regarding the response of natural oasis plants communities to various environmental factors.Nineteen sample plots(50 m×50 m)were selected in the Daliyabuyi Oasis in the Taklimakan Desert hinterland based on the location of groundwater monitoring wells and 76 vegetation quadrats(25 m×25 m)were established.A two-way indicator species analysis,Mantel test,detrended correspondence analysis,canonical correspondence analysis(CCA),and hierarchical partitioning were used to provide an in-depth analysis of community classification,species composition,and environmental interpretation of the oasis.A generalized linear model was used to verify the results which showed that the current oasis community could be divided into four types according to the dominant species,which is controlled by soil moisture.Measurement of species composition and distribution of communities showed significant differences between species diversity of individual community types.Variations in groundwater depth affects patterns of species diversity which is sensitive to richness,while the degree of surface water disturbance affects the pattern of species evenness.Moreover,the CCA ordination map showed that community distribution and diversity characteristics have their own preferences in habitat gradients.The study concluded that the species dominance of the community and the composition and distribution are not dominated by a single factor.There are differences in the scale and effect of different water resource types in maintaining community characteristics.Haobo Shi Feng Zhang Qingdong Shi Mengze Li Yue Dai Zipeng Zhang Chuanmei Zhu 2023Journal of Forestry Research2023,34,6:0
18Stress compensation based on interfacial nanostructures for stable perovskite solar cells显示文摘The long-term stability issue of halide perovskite solar cells hinders their commercialization.The residual stress-strain affects device stability,which is derived from the mismatched thermophysical and mechanical properties between adjacent layers.In this work,we introduced the Rb_(2)CO_(3)layer at the interface of SnO_(2)/perovskite with the hierarchy morphology of snowflake-like microislands and dendritic nanostructures.With a suitable thermal expansion coefficient,the Rb_(2)CO_(3)layer benefits the interfacial stress relaxation and results in a compressive stress-strain in the perovskite layer.Moreover,reduced nonradiative recombination losses and optimized band alignment were achieved.An enhancement of open-circuit voltage from 1.087 to 1.153 V in the resultant device was witnessed,which led to power conversion efficiency(PCE)of 22.7%(active area of 0.08313 cm^(2))and 20.6%(1 cm2).Moreover,these devices retained 95%of its initial PCE under the maximum power point tracking(MPPT)after 2700 h.It suggests inorganic materials with high thermal expansion coefficients and specific nanostructures are promising candidates to optimize interfacial mechanics,which improves the operational stability of perovskite cells.Cheng Zhu Xi Wang Hangxuan Li Chenyue Wang Ziyan Gao Pengxiang Zhang Xiuxiu Niu Nengxu Li Zipeng Xu Zhenhuang Su Yihua Chen Huachao Zai Haipeng Xie Yizhou Zhao Ning Yang Guilin Liu Xueyun Wang Huanping Zhou Jiawang Hong Xingyu Gao Yang Bai Qi Chen 2023Interdisciplinary Materials2023,2,2:0
19Gold nanoclusters conjugated berberine reduce inflammation and alleviate neuronal apoptosis by mediating M2 polarization for spinal cord injury repair显示文摘Spinal cord injury(SCI)leads to nerve cell apoptosis and loss of motor function.Herein,excessive activation of the M1 phenotype macrophages/microglia is found to be the main reason for the poor prognosis of SCI,but the selective activation phenotype(M2)macrophages/microglia facilitates the recovery of SCI.Thereafter,we used gold nanoclusters loaded berberine(BRB-AuNCs)to reduce inflammation by inhibiting the activation of M1 phenotype macrophages/microglia,which simultaneously inhibited neuronal apoptosis after SCI.In vitro and in vivo experiments showed that BRB-AuNCs reduced M1 protein marker CD86,increased M2 protein marker CD206,reduced inflammation and apoptotic cytokines(IL-1β,IL-6,TNF-α,Cleaved Caspase-3 and Bax).These results indicate that BRB-AuNCs have excellent anti-inflammatory and anti-apoptotic effects by inducing the polarization of macrophages/microglia from M1 phenotype to M2 phenotype.Thereafter,the motor functions of SCI rats were significantly improved after treatment with BRB-AuNCs.This work not only provides a new way for the treatment of SCI but also broadens BRB utilization strategies.Zipeng Zhou Dan Li Xiangyi Fan Yajiang Yuan Hongyu Wang Dahao Wang Xifan Mei 2022Regenerative Biomaterials2022,9,1:0
20The Super-large Ensemble Experiments of CAS FGOALS-g3显示文摘A super-large ensemble simulation dataset with 110 members has been produced by the fully coupled model FGOALS-g3 developed by researchers at the Institute of Atmospheric Physics,Chinese Academy of Sciences.This is the first dataset of large ensemble simulations with a climate system model developed by a Chinese modeling center.The simulation has the largest realizations up to now worldwide in terms of single-model initial-condition large ensembles.Each member includes a historical experiment(1850-2014)and an experiment(2015-99)under the very high greenhouse gas emissions Shared Socioeconomic Pathway scenario(SSP5-8.5).The dataset includes monthly and daily temperature,precipitation,and other variables,requiring storage of 275 TB.Additionally,the surface air temperature(SAT)and land precipitation simulated by the FGOALS-g3 super-large ensemble have been validated and projected.The ensemble can capture the response of SAT and land precipitation to external forcings well,and the internal variabilities can be quantified.The availability of more than 100 realizations will help researchers to study rare events and improve the understanding of the impact of internal variability on forced climate changes.Pengfei LIN Bowen ZHAO Jilin WEI Hailong LIU Wenxia ZHANG Xiaolong CHEN Jie JIANG Mengrong DING Wenmin MAN Jinrong JIANG Xu ZHANG Yuewen DING Wenrong BAI Chenyang JIN Zipeng YU Yiwen LI Weipeng ZHENG Tianjun ZHOU 2022Advances in Atmospheric Sciences2022,39,10:0
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