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| 1 | Efficacy and safety of Yinchenwuling powder for hyperlipidemia: a systematic review and Meta-analysis显示文摘OBJECTIVE:To assess the clinical effectiveness and adverse effects of Yinchenwuling powder(YCWLP)in the treatment of hyperlipidemia using Meta-analysis.METHODS:Seven electronic databases were searched for randomized controlled trials designed to evaluate the clinical effectiveness of YCWLP for hyperlipidemia published in any language prior to February 2015.Two reviewers independently identified articles,extracted data,assessed quality,and cross-checked the results.Revman 5.3 was used to analyze the data.RESULTS:Only five randomized controlled trials with poor methodology were included in the analy-sis.The five trials compared YCWLP with conventional lipid-lowering drugs.Meta-analysis indicated that YCWLP was more effective at the levels of total cholesterol and triglycerides,while increasing the level of high-density lipoprotein cholesterol without serious adverse effects.However,it was not more effective than lipid-lowering drugs in reducing low-density lipoprotein cholesterol and improving hemorheology.CONCLUSION:YCWLP appeared to improve lipid levels.However,given the high risk of bias among the trials,we could not conclude that YCWLP was beneficial to patients with hyperlipidemia.More rigorous trials are required to provide stronger evidence for the conclusion. | Yao Haiqiang Zhang Zengliang Wang Ji Zuo Jiacheng Chen Yu Zhu Libing Li Xiaoke Yang Zheng Wang Zisong Sun Ranran Xu Xuanxuan Li Changming Wu Yanling Li Lingru Wang Qi | 2016 | Journal of Traditional Chinese Medicine2016，36，2： | 11 |
| 2 | Improving the resistance of eggplant ( Solanum melongena ) to Verticillium wilt using wild species Solanum linnaeanum显示文摘 | Jun Liu Zisong Zheng Xiaohui Zhou Cui Feng Yong Zhuang | 2015 | Euphytica2015，，3： | 1 |
| 3 | Evaluation of abundant hydrocarbon-generation depressions in the deepwater area of Qiongdongnan Basin,South China Sea显示文摘It has been confirmed that the key source rocks of Qiongdongnan Basin are associated with the Yacheng Formation, which was deposited in a transitional marine-continental environment. Because the distribution and evolution patterns of the source rocks in the major depressions are different, it is important to determine the most abundant hydrocarbon-generation depressions in terms of exploration effectiveness. Based on an analysis of organic matter characteristics of the source rocks, in combination with drilling data and seismic data, this paper establishes a model to evaluate the hydrocarbon-generation depressions in the deepwater area of Qiongdongnan Basin. First of all, by using the method of seismic-facies model analysis, the distribution of sedimentary facies was determined. Then, the sedimentary facies were correlated with the organic facies, and the distribution of organic facies was predicted. Meanwhile, the thickness of source rocks for all the depressions was calculated on the basis of a quantitative analysis of seismic velocity and lithology. The relationship between mudstone porosity and vitrinite reflectance(Ro) was used to predict the maturity of source rocks. Second, using the parameters such as thickness and maturity of source rocks, the quantity and intensity of gas generation for Yacheng and Lingshui Formations were calculated. Finally, in combination with the identified hydrocarbon resources, the quantity and intensity of gas generation were used as a guide to establish an evaluation standard for hydrocarbon-generation depressions, which was optimized for the main depressions in the Central Depression Belt. It is proposed that Lingshui, Ledong, Baodao and Changchang Depressions are the most abundant hydrocarbon depressions, whilst Songnan and Beijiao Depressions are rich hydrocarbon depressions. Such an evaluation procedure is beneficial to the next stage of exploration in the deep-water area of Qiongdongnan Basin. | LIU Zhen SUN Zhipeng WANG Zisong ZHANG Wei LI Tingan HE Weijun LI Fengxia CAO Shang LIU Jingjing LIN Lu | 2016 | Acta Oceanologica Sinica2016，35，2： | 1 |
| 4 | Guanyu“cunzai”he“shi”关于“存在”和“是”[On“exist-ence'and'being']显示文摘 | Wang Zisong(汪子嵩) &TaiqingWang(王太庆) | 2000 | 复旦学报:社会科学版2000，1，： | 1 |
| 5 | Multiplicity-induced optimal gains of an inverted pendulum system under a delayed proportional-derivative-acceleration feedback显示文摘This paper studies the stabilization to an inverted pendulum under a delayed proportional-derivative-acceleration(PDA)feedback,which can be used to understand human balance in quiet standing.The closed-loop system is described by a neutral delay differential equation(NDDE).The optimal feedback gains(OFGs)that make the exponential decaying rate maximized are determined when the characteristic equation of the closed-loop has a repeated real root with multiplicity 4.Such a property is called multiplicity-induced dominancy of time-delay systems,and has been discussed intensively by many authors for retarded delay differential equations(RDDEs).This paper shows that multiplicity-induced dominancy can be achieved in NDDEs.In addition,the OFGs are delay-dependent,and decrease sharply to small numbers correspondingly as the delay increases from zero and varies slowly with respect to moderate delays.Thus,the inverted pendulum can be well-stabilized with moderate delays and relatively small feedback gains.The result might be understandable that the elderly with obvious response delays can be well-stabilized with a delayed PDA feedback controller. | Zisong MEI Zaihua WANG | 2022 | Applied Mathematics and Mechanics(English Edition)2022，43，11： | 1 |
| 6 | Study on the mechanism of Wikstroemia indica in the treatment of inflammatory diseases based on network pharmacology显示文摘Wiksroemia indica belongs to the family of Thymelaeaceae.As a material of Traditional Chinese Medicine,it is mainly used to treat inflammation-related diseases.However,due to its complex composition,the scientific basis for its traditional application is still insufficient and the mechanism of action is still unclear.At present,most studies on its anti-inflammatory effect focus on a certain component and its different solvent fractions.There are few reports about the synergistic mechanism of the constituents from W.indica for the treatment of inflammatory diseases.Therefore,the present study aimed to uncover its potential mechanism from a holistic perspective using the network pharmacology approach.Firstly,compounds in W.indica and genes associated with inflammatory diseases were obtained.Then,the active compounds were screened out and their targets were predicted.After that,the key targets for W.indica to treat inflammatory diseases were screened out.Finally,the protein-protein interaction(PPI),Gene ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)enrichment analyses of key targets were performed to further study the mechanism of W.indica in the treatment of inflammatory diseases.The results showed that the active constituents of W.indica might play an anti-inflammatory role through the key targets CYP19A1 and CYP1B1,which clarified the primary mechanism for the treatment of inflammatory diseases and provided a scientific basis for further study of this herb. | Jiayi Li Zisong Bai Tingting Guo Heng Zhang Gang Chen Di Zhou Ning Li | 2021 | Asian Journal of Traditional Medicines2021，16，1： | 0 |
| 7 | DQL-Based Intelligent Scheduling Algorithm for Automatic Driving in Massive MIMO V2I Scenarios显示文摘Connected and autonomous vehicle(CAV)vehicle to infrastructure(V2I)scenarios have more stringent requirements on the communication rate,delay,and reliability of the Internet of vehicles(Io V).New radio vehicle to everything(NR-V2X)adopts link adaptation(LA)to improve the efficiency and reliability of road safety information transmission.In order to solve the problem that the existing LA scheduling algorithms cannot adapt to the Doppler shift and complex fast time-varying channel in V2I scenario,resulting in low reliability of information transmission,this paper proposes a deep Q-learning(DQL)-based massive multiple-input multiple-output(MIMO)LA scheduling algorithm for autonomous driving V2I scenario.The algorithm combines deep neural network(DNN)with Q-learning(QL)algorithm,which is used for joint scheduling of modulation and coding scheme(MCS)and space division multiplexing(SDM).The system simulation results show that the algorithm proposed in this paper can fully adapt to the different channel environment in the V2I scenario,and select the optimal MCS and SDM for the transmission of road safety information,thereby the accuracy of road safety information transmission is improved,collision accidents can be avoided,and bring a good autonomous driving experience. | Yong Liao Zisong Yin Zhijing Yang Xuanfan Shen | 2023 | China Communications2023，20，3： | 0 |
| 8 | Research,rethink and revolutionize rice breeding:an interview with Qifa Zhang显示文摘More than 100 Nobel laureates recently signed a letter urging Greenpeace to end its opposition to genetically modified organisms(GMOs).With an ever-increasing demand for food,China finds itself confronted with the same question:is it time to rethink and reassess its stance towards GMO?Rice is one of the most important food crops in China and around the world.In recent years,Chinese scientists | Zisong Ma | 2016 | National Science Review2016，3，3： | 0 |
| 9 | Bioactive Constituents of the Seed Kernels from Vernicia fordii显示文摘A new compound,(2′R)-(5-oxo-2,5-dihydrofuran-2-yl)methyl octanoate(1),together with 9 known ones(2-10)were isolated from the bioactive extract of the seed kernels from Vernicia fordii.Their structures were determined by spectroscopic analyses,including Nuclear Magnetic Resonance(NMR)and High Resolution Electrospray Ionization Mass Spectroscopy(HRESI-MS).Their cytotoxicities against three human cancer cell lines(A549,HepG2 and Caco2 cells)and anti-neuroinflammatory effects were evaluated.Cytotoxicity assay revealed that compound 9 could inhibit the growth of HepG2 cells,while compound 6 had a moderate inhibitory effect against A549 cells.Further anti-neuroinflammatory activity assay showed that compound 10 exhibited moderate inhibitory effect on the release of NO in LPS-stimulated BV2 microglia cells. | Jiayi Li Jing Ding Zisong Bai Gang Chen Di Zhou Ning Li | 2020 | Asian Journal of Traditional Medicines2020，15，5： | 0 |
| 10 | Rhodium(Ⅲ)-catalyzed [3+2] annulative coupling between oximes and electron-deficient alkynes显示文摘Rhodium(III)-catalyzed coupling between ketoximes and alkynes via C–H activation and annulation typically followed the[4+2]selectivity to afford isoquinolines.By designing alkynes bearing a highly electron-withdrawing group and under substrate control,we have successfully switched the selectivity of the coupling between oximes and alkynes to the alternative[3+2]annulation,leading to the efficient synthesis of indenamines.This process features good regioselectivity for both substrates,high efficiency,broad substrate scope,and excellent functional group tolerance. | Xukai Zhou Songjie Yu Zisong Qi Xingwei Li | 2015 | Science China Chemistry2015，58，8： | 0 |
| 11 | Research on medical data storage and sharing model based on blockchain显示文摘With the process of medical informatization,medical diagnosis results are recorded and shared in the form of electronic data in the computer.However,the security of medical data storage cannot be effectively protected and the unsafe sharing of medical data among different institutions is still a hidden danger that cannot be underestimated.To solve the above problems,a secure storage and sharing model of private data based on blockchain technology and homomorphic encryption is constructed.Based on the idea of blockchain decentralization,the model maintains a reliable medical alliance chain system to ensure the safe transmission of data between different institutions;A privacy data encryption and computing protocol based on homomorphic encryption is constructed to ensure the safe transmission of medical data;Using its complete anonymity to ensure the Blockchain of medical data and patient identity privacy;A strict transaction control management mechanism of medical data based on Intelligent contract automatic execution of preset instructions is proposed.After security verification,compared with the traditional medical big data storage and sharing mode,the model has better security and sharing. | Jian Zhao Wenqian Qiang Zisong Zhao Tianbo An Zhejun Kuang Dawei Xu Lijuan Shi | 2023 | High-Confidence Computing2023，3，3： | 0 |
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