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| 1 | 亚太地区胃食管反流病的处理共识:更新版显示文摘背景与目的:自从2004年亚太地区胃食管反流病(GERD)共识发表以来,更多关于GERD流行病学和处理的文献资料相继出现。有必要对这些资料进行循证综述,对共识作出更新。方法:由多学科专家组应用德尔菲(Delphi)法制定共识条文,提呈相关资料,并对证据质量、推荐力度和共识水平进行分级。结果:亚洲GERD发生率日益增加。其危险因素包括老年、男性、种族、家族史、社会经济地位高、体重指数增加和吸烟。对于有典型症状而无报警症状的患者,对质子泵抑制剂(PPI)试验有症状应答具有诊断意义。如PPI试验失败,停止治疗后pH监测结果阴性可排除GERD。窄带成像、胶囊内镜检查和无线pH监测的作用尚未明确。亚洲诊断策略的制定须考虑到并存的胃癌和消化性溃疡。减轻体质量和抬高床头可改善反流症状。PPIs是最有效的内科治疗手段。对于非糜烂性反流病(NERD)患者,按需治疗较为适宜。有慢性咳嗽、喉炎和典型GERD症状的患者在排除非GERD病因后,应予PPI每天两次治疗。如有经验丰富的外科医师,GERD患者可行胃底折叠术。除临床试验外,GERD不应采用内镜治疗。结论:新的诊断方法和内镜治疗的作用有待进一步研究阐明。亚洲GERD诊断策略的制定须考虑到并存的胃癌和消化性溃疡。PPIs仍为治疗的基石。 | Kwong Ming Fock Nicholas J Talley Ronnie Fass Khean Lee Goh Peter Katelaris Richard Hunt Michio Hongo Tiing Leong Ang Gerald Holtmann Sanjay Nandurkar San Ren Lin Benjamin CY Wong Francis KL Chan Abdul Aziz Rani Young-Tae Bak Jose Sollano Khek Yu Ho Sathoporn Manatsathit 钱本余 | 2008 | 胃肠病学2008，13，7： | 21 |
| 2 | Overall rate, location, and predictive factors for positive surgical margins after robot-assisted laparoscopic radical prostatectomy for high-risk prostate cancer显示文摘我们与高风险的前列腺癌症在 271 个病人报导全面的率,地点和积极外科的边缘(PSM ) 的预兆的因素。在 2008 年 4 月和 2011 年 10 月之间,我们有希望地从作为 D'Amico 分类的病人收集了数据高风险经历了帮助机器人的 laparoscopic 激进分子前列腺切除术。PSM 的全面的率和地点被报导。逐步的逻辑回归模型被适合估计 PSM 的预兆的因素。PSM 的全面的率是 25.1%(271 个病人中的 68 个) 。这些 PSM,(68 中的 26 个)38.2% 是 posterolateral (PL ) , 26.5%(68 中的 18 个) multifocal, 16.2%(68 中的 11 个) 在顶, 14.7%(68 中的 10 个) 在膀胱颈,并且 4.4%(3/68 ) 在另外的地点。有病理学的阶段 pT2 的病人的 PSM 率是 8.6%(140 中的 12 个) , 26.6%(64 中的 17 个) pT3a, 53.3%(32/60 ) pT4 的 pT3b,和 100%(7 中的 7 个) 。在包括 pre- , intra- ,和手术后的参数的一个逻辑回归模型,身体团索引(机会比率[或] :1.09;95% 信心间隔[CI ] :1.01-1.19, P= 0.029 ) ,病理学的舞台(pT3b 或更高对 pT2;或:5.14;95% CI:1.92-13.78;P = 0.001 ) 并且肿瘤的百分比(或:46.71;95% CI:6.37-342.57;P < 0.001 ) 是为 PSM 的独立预兆的因素。在病人在的 PSM 的最普通的地点高风险是 PL 方面,它反映报导肿瘤攻击性。PSM 的唯一的重要预兆的因素是病理学的结果,例如在标本和病理学的舞台的肿瘤的百分比。 | Sung Gu Kang Oscar Schatloff Abdul Muhsin Haidar Srinivas Samavedi Kenneth J Palmer Jun Cheon Vipul R Patel | 2016 | Asian Journal of Andrology2016，18，1： | 9 |
| 3 | Carbonic anhydrase enzymes Ⅱ, Ⅶ, Ⅸ and Ⅻ in colorectal carcinomas显示文摘AIM To investigate expression of four alpha-carbonic anhydrases(CAs) in colorectal carcinomas(CRC) and compare the results with patients' survival.METHODS Colorectal carcinoma samples from 539 CRC patients and control tissues were arranged as tissue microarrays and analyzed with antibodies against CA Ⅱ, CA Ⅶ, CA Ⅸ, and CA Ⅻ. Intensity and extent of staining were both scored from 0 to 3 in each sample. These enzyme expression levels were then correlated to patients' survival and clinicopathological parameters, which were tumor differentiation grade and stage, site of tumor, patients' age, and gender. Kaplan-Meier analysis and Cox regression hazard ratio model were used to analyze survival data. RESULTS CA Ⅱ and CA Ⅻ staining intensities correlated with patients' survival in that higher expression indicated poorer prognosis. In Cox regression analysis one unit increase in the CA Ⅱ intensity increased the hazard ratio to 1.19 fold(CI: 1.04-1.37, P = 0.009). A significant correlation was also found when comparing CA Ⅻ staining intensity with survival of CRC patients(HR = 1.18, 95%CI: 1.01-1.38, P = 0.036). The extent of CA Ⅻ immunostaining did not correlate to the patients' survival(P = 0.242, Kaplan-Meier analysis). A significant interaction between age group and extent of the CA Ⅱ staining was found. Increased extent of CA Ⅱ had a significant hazard ratio among patients 65 years and older(1.42, 95%CI: 1.16-1.73, P = 0.0006). No correlations were found between CA Ⅶ(intensity P = 0.566, extent P = 0.495, Kaplan-Meier analysis), or CA Ⅸ(intensity P = 0.879, extent P = 0.315, KaplanMeier analysis) immunostaining results and survival, or the other parameters. CONCLUSION The present findings indicate that CA Ⅱ and CA Ⅻ could be useful in predicting survival in CRC. | Pia Viikil? Antti J Kivel? Harri Mustonen Selja Koskensalo Abdul Waheed William S Sly Jaromir Pastorek Silvia Pastorekova Seppo Parkkila Caj Haglund | 2016 | World Journal of Gastroenterology2016，22，36： | 3 |
| 4 | Technique for rapid detection of phthalates in water and beverages显示文摘 | Asif I. Zia Mohd Syaifudin Abdul Rahman Subhas Chandra Mukhopadhyay Pak-Lam Yu I.H. Al-Bahadly Chinthaka P. Gooneratne Jǘrgen Kosel Tai-Shan Liao | 2013 | Journal of Food Engineering2013，，2： | 2 |
| 5 | The effect of biodiesel oxidation on engine performance and emissions 显示文摘 | ABDUL M GERPEN J | 2001 | Biomass and Bioenergy2001，20，4： | 1 |
| 6 | Green synthesis of gold nanoparticles using seed aqueous extract of Abelmoschus esculentus and its antifungal activity显示文摘 | Chidambaram J Rajendiran R Abdul A R | 2013 | Industrial Crops and Products2013，45，： | 1 |
| 7 | Permeability studies of artificial and natural cancellous bone structures显示文摘 | Syahrom A Abdul KMR Abdullah J | 2013 | Med Eng Phys2013，35，6： | 1 |
| 8 | Laser welding of low carbon steel and thermal stress analysis 显示文摘 | Yilbas B S Arif A F M Abdul Aleem B J | 2010 | Optics & Laser Technology2010，42，5： | 1 |
| 9 | Policies for a single- vendor multi-buyer system with finite production rate 显示文摘 | Abdul J B Gutierrez J Sicilia M J | 2008 | Decision Support Systems2008，46，： | 1 |
| 10 | Tile optimal demand for foreign exchange reserves in Pakistan显示文摘 | Abdul J Sheharvar B | 2008 | International Journal of Applied Econometrics and Quantitative Studies2008，3348，： | 1 |
| 11 | The effect of a compatibilizer on the mechanical properties and mass swell of white rice husk ash filled natural rubber-linear low density polyethylene blends显示文摘 | Ismail H Nizam J M Abdul Khalil H P S | 2001 | Polymer Testing2001，20，2： | 1 |
| 12 | Electrolytic removal of hexavalent chromium from aqueous solutions显示文摘 | Abdul J Chaudhary Nimai C Goswami Susan M Grimes | 2003 | Journal of Chemical Technology & Biotechnology2003，78，8： | 1 |
| 13 | Transfusion associated CMV infection: Transfusion strategies for high risk patients显示文摘 | Munira J Shahina T Abdul A | 2010 | Bangladesh Journal of Medical Microbiology2010，4，2： | 1 |
| 14 | Distributed control of modular and reconfigurable robot with torque sensing 显示文摘 | LIU G J ABDUL S GOLDENBERG A A | 2008 | Robotica2008，26，： | 1 |
| 15 | Marek' s disease virus-induced transient paralysis is associated with cytokine gene expression in the nervous system显示文摘 | Abdul - areem M F Hunter B D Sarson A J | 2006 | Viral Immunol2006，19，2： | 1 |
| 16 | CSF neuroftlament protein (NFL) - a marker of active H1V-related neurodegeneration 显示文摘 | Abdulle S Mellgren A Brew B J | 2007 | J Neurol2007，254，8： | 1 |
| 17 | Optimal multi-siteresource allocation and utility planning for integrated rice mill complex 显示文摘 | Lim J S Abdul Manan Z Hashim H | 2013 | Industrial & Engineering Chemistry Research2013，52，10： | 1 |
| 18 | Irreducible inguinal hernia in children显示文摘 | Abdul Salam Abdul Aziz | 1998 | Pak J Surg1998，14，： | 1 |
| 19 | Comparison of nutri- tional and inflammatory markers in dialysis patients with reduced appetite显示文摘 | Juan J C Abdul R Q Jonas A | 2007 | Am J Clin Nutr2007，85，3： | 1 |
| 20 | The impact of patient to nurse ratio on quality of care and patient safety in the medical and surgical wards in malaysian private hospitals : A Cross - sectional Study 显示文摘 | Mufaman J Hamzah AR Abdul SS | 2015 | Asian Soc Sci2015，11，9： | 1 |
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