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| 1 | Endoscopic mucosal resection vs endoscopic submucosal dissection for superficial non-ampullary duodenal tumors显示文摘BACKGROUND The selection of endoscopic treatments for superficial non-ampullary duodenal epithelial tumors(SNADETs)is controversial.AIM To compare the efficacy and safety of endoscopic mucosal resection(EMR)and endoscopic submucosal dissection(ESD)for SNADETs.METHODS We retrospectively analyzed the data of patients with SNADETs from a database of endoscopic treatment for SNADETs,which included eight hospitals in Fukuoka,Japan,between April 2001 and October 2017.A total of 142 patients with SNADETs treated with EMR or ESD were analyzed.Propensity score matching was performed to adjust for the differences in the patient characteristics between the two groups.We analyzed the treatment outcomes,including the rates of en bloc/complete resection,procedure time,adverse event rate,hospital stay,and local or metastatic recurrence.RESULTS Twenty-eight pairs of patients were created.The characteristics of patients between the two groups were similar after matching.The EMR group had a significantly shorter procedure time and hospital stay than those of the ESD group[median procedure time(interquartile range):6(3-10.75)min vs 87.5(68.5-136.5)min,P<0.001,hospital stay:8(6-10.75)d vs 11(8.25-14.75)d,P=0.006].Other outcomes were not significantly different between the two groups(en bloc resection rate:82.1%vs 92.9%,P=0.42;complete resection rate:71.4%vs 89.3%,P=0.18;and adverse event rate:3.6%vs 17.9%,P=0.19,local recurrence rate:3.6%vs 0%,P=1;metastatic recurrence rate:0%in both).Only one patient in the ESD group underwent emergency surgery owing to intraoperative perforation.CONCLUSION EMR has significantly shorter procedure time and hospital stay than ESD,and provides acceptable curability and safety compared to ESD.Accordingly,EMR for SNADETs is associated with lower medical costs. | Mitsuru Esaki Kazuhiro Haraguchi Kazuya Akahoshi Naru Tomoeda Akira Aso Soichi Itaba Haruei Ogino Yusuke Kitagawa Hiroyuki Fujii Kazuhiko Nakamura Masaru Kubokawa Naohiko Harada Yosuke Minoda Sho Suzuki Eikichi Ihara Yoshihiro Ogawa | 2020 | World Journal of Gastrointestinal Oncology2020，12，8： | 2 |
| 2 | Preparation and characterization of inclusion complexes of poly(propylene glycol) with cyclodexlrins显示文摘 | Akira Harada Miyuko Okada Jun Li | 1995 | Macromolecules1995，28，： | 1 |
| 3 | Curdlan:a baterial gelforming β -1,3-Glucan显示文摘 | Tokuya Harada Akira Misali Hirose Saito | 1968 | Archive of Biochemistry and Biophysics1968，124，： | 1 |
| 4 | Anatomic and molecular pathology of intrahepatic cholangiocarcinoma显示文摘 | Yasuni Nakanuma Kenichi Harada Akira Ishikawa Yoh Zen Motoko Sasaki | 2003 | Journal of Hepato - Biliary - Pancreatic Surgery2003，，4： | 1 |
| 5 | Comparison of protein phosphatase inhibitory activity and apparent toxicity of microcystins and related compounds显示文摘 | Emiko Ito Akira Takai Fumio Kondo Hiroaki Masui Susumu Imanishi Ken-ichi Harada | 2002 | Toxicon2002，，7： | 1 |
| 6 | Cdc42 is required for chondrogenesis and interdigital programmed cell death during limb development显示文摘 | Ryo Aizawa Atsushi Yamada Dai Suzuki Tadahiro Iimura Hidetoshi Kassai Takeshi Harada Masayuki Tsukasaki Gou Yamamoto Tetsuhiko Tachikawa Kazuki Nakao Matsuo Yamamoto Akira Yamaguchi Atsu Aiba Ryutaro Kamijo | 2012 | Mechanisms of Development (-)2012，，1： | 1 |
| 7 | Effects of strain and cultivation medium on the chemical composition of the taste components in fruit-body of Hypsizygus marmoreus 显示文摘 | Akira Harada Seiki Gisusi Shozo Yoneyama | 2004 | Food Chemistry2004，84，2： | 1 |
| 8 | Changes in contents of free amino acids and soluble carbohydrates during fruit-body development of Hypsizygus marmoreus 显示文摘 | Akira Harada Shozo Yoneyama Shuichi Doi | 2003 | Food Chemistry2003，83，3： | 1 |
| 9 | Plasma Concentration of Endothelin-1 Does Not Reflect Renal Vasoconstriction as Estimated by Duplex Ultrasonography in Cirrhosis显示文摘 | Hiroshi Kitamura Ryo Shimada Akira Kobayashi Kazuhiko Nomura Terumasa Noike Haruhisa Harada Shinichi Miyagawa Seiji Kawasaki | 1997 | Digestive Diseases and Sciences1997，，3： | 1 |
| 10 | Effects of strain and cultivation medium on the chemical composition of the taste components in fruit-body of Hypsizygus marmoreus 显示文摘 | Akira Harada Seiki Gisusi Shozo Yoneyama | 2004 | Food Chemistry2004，84，2： | 1 |
| 11 | Doppler Echocardiographic Findings of Indomethacin-Induced Occlusion of the Fetal Ductus Arteriosus显示文摘 | Yasushi Takahashi Kenji Harada Akira Ishida Toshinobu Tanaka Akira Tsuda Goro Takada | 1996 | Amer J Perinatol1996，，01： | 1 |
| 12 | Curdlan: a bacterial gel-forming β-1,3-Glucan显示文摘 | Tokuya Harada Akira Misaki Hirose Saito | 1968 | Archive of Biochemistry and Biophysics1968，124，： | 1 |
| 13 | Cyclodextrin-based molecular machines 显示文摘 | Akira Harada | 2001 | Acc Chem Res2001，34，： | 1 |
| 14 | Factors associated with a poor response to gefitinib in the NEJ002 study: Smoking and the L858R mutation显示文摘 | Tatsuro Fukuhara Makoto Maemondo Akira Inoue Kunihiko Kobayashi Shunichi Sugawara Satoshi Oizumi Hiroshi Isobe Akihiko Gemma Masao Harada Hirohisa Yoshizawa Ichiro Kinoshita Yuka Fujita Yasuo Saijo Koichi Hagiwara Satoshi Morita Toshihiro Nukiwa | 2015 | Lung Cancer2015，，： | 1 |
| 15 | Continuous EGFR-TKI administration following radiotherapy for non-small cell lung cancer patients with isolated CNS failure显示文摘 | Takehito Shukuya Toshiaki Takahashi Tateaki Naito Rieko Kaira Akira Ono Yukiko Nakamura Asuka Tsuya Hirotsugu Kenmotsu Haruyasu Murakami Hideyuki Harada Koichi Mitsuya Masahiro Endo Yoko Nakasu Kazuhisa Takahashi Nobuyuki Yamamoto | 2011 | Lung Cancer2011，，3： | 1 |
| 16 | Preparation of long sticky ends for universal ligation-independent cloning: Sequential T4 DNA polymerase treatments显示文摘 | Akira Tachibana Kazuo Tohiguchi Takayuki Ueno Yuichi Setogawa Ayako Harada Toshizumi Tanabe | 2009 | Journal of Bioscience and Bioengineering2009，，6： | 1 |
| 17 | An-titumor effects of systemic and local immunization with aCTL-directed peptide in combination with a local injec-tion of OK-432显示文摘 | Takeharu Ono Mamoru Harada Akira Yamada | 2006 | Clin Cancer Res2006，，12： | 1 |
| 18 | Preparation and characterization of inclusion complexes of polyisobutylene with cyclodextrins 显示文摘 | Akira Harada Syukuko Suzuki MiyukoOkada Mikiharu Kamaehi | 1996 | Macromolecules1996，29，： | 1 |
| 19 | Effects of micro-environmental factors on photosynthetic CO2 uptake and carbon fixation metabolism in a spring ephemeral, Erythronium japonicum, growing in native and open habitats显示文摘 | Shinichi Sawada Akira Harada Yoshiko Asari Sachie Asano Makoto Kuninaka Hitomi Kawamura Minobu Kasai | | 0，1999，： | 1 |
| 20 | Giant cavernous hepatic hemangioma shrunk by use of sorafenib显示文摘 | Satoyoshi Yamashita Kohsuke Okita Katsunori Harada Atsuyoshi Hirano Teruaki Kimura Akira Kato Kiwamu Okita | 2013 | Clinical Journal of Gastroenterology2013，，1： | 1 |
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