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| 1 | Effects of Paricalcitol and Enalapril on Atherosclerotic Injury in Mouse Aortas显示文摘 | Husain Kazim Suarez Edu Isidro Angel Ferder Leon | 2010 | American Journal of Nephrology2010，，4： | 2 |
| 2 | The Origin of the Spinal Subdural Space:Ultrastructure Findings显示文摘 | Miguel Angel Reina MD Oscar De Leon Casasola MD Andres Lopez MD Jose Antonio De Andres MD Miguel Mora MD and Agustin Fernandez MD | 2002 | Anesth Analg2002，94，4： | 1 |
| 3 | Effect of Cardiac Resynchronization Therapy on Left Ventricular Size and Function in Chronic Heart Failure显示文摘 | Martin G. St John Sutton Ted Plappert William T. Abraham Andrew L. Smith David B. DeLurgio Angel R. Leon Evan Loh Dusan Z. Kocovic Westby G. Fisher Myrvin Ellestad John Messenger Kristin Kruger Kathryn E. Hilpisch Michael R.S. Hill | 2003 | Circulation: Journal of the American Heart Association2003，，： | 1 |
| 4 | Results of the Predictors of Response to CRT (PROSPECT) Trial显示文摘 | Eugene S. Chung Angel R. Leon Luigi Tavazzi Jing-Ping Sun Petros Nihoyannopoulos John Merlino William T. Abraham Stefano Ghio Christophe Leclercq Jeroen J. Bax Cheuk-Man Yu John Gorcsan Martin St John Sutton Johan De Sutter Jaime Murillo | 2008 | Circulation2008，，： | 1 |
| 5 | A direct comparison in the fatigue resistance enhanced by surface severe plastic deformation and shot peening in a C-2000 superalloy显示文摘 | Leon L. Shaw Jia-Wan Tian Angel L. Ortiz Kun Dai Juan C. Villegas Peter K. Liaw Ruiming Ren Dwaine L. Klarstrom | 2009 | Materials Science & Engineering A2009，，4： | 1 |
| 6 | Results of the Predictors of Response to CRT (PROSPECT) Trial显示文摘 | Eugene S. Chung Angel R. Leon Luigi Tavazzi Jing-Ping Sun Petros Nihoyannopoulos John Merlino William T. Abraham Stefano Ghio Christophe Leclercq Jeroen J. Bax Cheuk-Man Yu John Gorcsan Martin St John Sutton Johan De Sutter Jaime Murillo | 2008 | Circulation2008，，20： | 1 |
| 7 | Autoregres- sive conditional volatility, skewness and kurtosis 显示文摘 | Angel Leon Gonzalo Rubio Gregorio Serna | 2005 | The Quarterly Review of Economics and Finance2005，45，23： | 1 |
| 8 | Safety and Efficacy of a Subcutaneous Implantable-Defibrillator显示文摘 | Martin Burke Bradley Knight Michael R. Gold Angel Leon John M. Herre Margaret Hood Mayer Rashtian Mark Kremers Ian Crozier Kerry L. Lee Warren Smith Raul Weiss | 2012 | Heart Rhythm2012，，9： | 1 |
| 9 | Nonalcoholic Fatty Liver Disease Epidemic and Its Implications for Liver Transplantation显示文摘 | Nyingi Kemmer Guy W. Neff Edson Franco Hussein Osman-Mohammed John Leone Erin Parkinson Elizabeth Cece Angel Alsina | 2013 | Transplantation Journal2013，，10： | 1 |
| 10 | A direct comparison in the fatigue resistance enhanced by surface severe plastic deformation and shot peening in a C-2000 superalloy显示文摘 | Leon L. Shaw Jia-Wan Tian Angel L. Ortiz Kun Dai Juan C. Villegas Peter K. Liaw Ruiming Ren Dwaine L. Klarstrom | 2009 | Materials Science & Engineering A2009，，4： | 1 |
| 11 | Measurement of Formal Harmonization Progress: The IASC Experi- ence 显示文摘 | Pascual Garrido Angel Leon Ana Zorio | 2002 | The International Journal of Accounting2002，37，1： | 1 |
| 12 | A TSH- CREBI-microRNA loop is required for thyroid cell growth 显示文摘 | LEONE V D'ANGEL() D FERRARO A | 2011 | MolEndocrinol2011，25，10： | 1 |
| 13 | Obesity portends increased morbidity and earlier recurrence following liver transplantation for hepatocellular carcinoma显示文摘 | Abhishek Mathur Edson S. Franco John P. Leone Hussein Osman‐Mohamed Haydy Rojas Nyingi Kemmer Guy W. Neff Alexander S. Rosemurgy Angel E. Alsina | 2013 | HPB2013，，7： | 1 |
| 14 | Post-shock metabolic response显示文摘 | Cuthbertson DP Angeles VZM Leon SM | 2001 | Nutr Hosp2001，16，5： | 1 |
| 15 | Measurement of Formal Harmonization Progress:The IASC Experience显示文摘 | Garrido Pascual Angel Leon Ana Zorio | 2002 | The International Journal of Accounting2002，37，1： | 1 |
| 16 | Effect of paricalcitol and enalapril on renal inflammation/oxidative stress in atherosclerosis显示文摘AIM: To investigate the protective effect of paricalcitol and enalapril on renal inflammation and oxidative stress in Apo E-knock out mice. METHODS: Animals treated for 4 mo as group(1) Apo E-knock out plus vehicle, group(2) Apo E-knock out plus paricalcitol(200 ng thrice a week),(3) Apo Eknock out plus enalapril(30 mg/L),(4) Apo E-knock out plus paricalcitol plus enalapril and(5) normal. Blood pressure(BP) was recorded using tail cuff method. The kidneys were isolated for biochemical assays using spectrophotometer and Western blot analyses. RESULTS: Apo E-deficient mice developed high BP(127 ± 3 mm Hg) and it was ameliorated by enalapril and enalapril plus paricalcitol treatments but not with paricalcitol alone. Renal malondialdehyde concentrations, p22 phox, manganese-superoxide dismutase, inducible nitric oxide synthase(NOS), monocyte chemoattractant protein-1, tumor necrosis factor-alpha and transforming growth factor-β1 levels significantly elevated but reduced glutathione, Cu Zn-SOD and e NOS levels significantly depleted in Apo E-knock out animals compared to normal. Administration of paricalcitol, enalapril and combined together ameliorated the renal inflammation and oxidative stress in Apo E-knock out animals. CONCLUSION: Paricalcitol and enalapril combo treatment ameliorates renal inflammation as well as oxidative stress in atherosclerotic animals. | Kazim Husain Edu Suarez Angel Isidro Wilfredo Hernandez Leon Ferder | 2015 | World Journal of Biological Chemistry2015，6，3： | 1 |
| 17 | Optimization of mycelial growth of Xylaria papulis Lloyd(Xylariaceae)in indigenous liquid culture conditions,science city of Muñoz,Nueva Ecija,Philippines显示文摘The search for potential and inexhaustible sources of bioactive compounds with great functional activities is imperative for potential drug leads in treating various human diseases.In this regard,this study investigated the optimum liquid medium and physical culture conditions for the mycelial growth of X.papulis Lloyd for nutraceutical studies.The greatest mycelial biomass was achieved in PSB liquid medium among the indigenous media evaluated,such as potato sucrose broth(PSB),corn meal broth(CMB),rice bran broth(RBB),and coconut water(CW).In terms of pH,X.papulis Lloyd was observed to grow in a wide range of pH(5.0−8.5),but the best mycelial growth was observed at pH 6.5.Room temperature of 28℃,lighted(137 lux),and static conditions were the other optimum physical culture conditions for mycelial growth of X.papulis Lloyd. | Mark Kevin S.Lopez Sofronio P.Kalaw Rich Milton R.Dulay Angeles M.De Leon Renato G.Reyes | 2022 | Studies in Fungi2022，7，1： | 0 |
| 18 | Clinical and anatomic predictors of need for repeat atrial fibrillation ablation显示文摘AIM To identify predictors of need for repeat procedures after initial atrial fibrillation(AF) ablation. METHODS We identified a cohort undergoing first time AF ablation at our institution from January 2004 to February 2014 who had cardiac magnetic resonance(CMR) imaging performed prior to ablation. Clinical variables and anatomic characteristics(determined from CMR) were assessed as predictors of need for repeat ablation. The decision regarding need for and timing of repeat ablation was at the discretion of the treating physician. RESULTS From a cohort of 331 patients, 142 patients(43%) underwent repeat ablation at a mean of 13.6 ± 18.4 mo afterthe index procedure. Both male gender(81% vs 71%, P = 0.05) and lower ejection fraction(57.4% ± 10.3% vs 59.8% ± 9.4%, P = 0.04) were associated with need for repeat ablation. On pre-ablation CMR, mean pulmonary vein(PV) diameters were significantly larger in all four PVs among patients requiring repeat procedures. In multivariate analysis, increased right superior PV diameter significantly predicted need for repeat ablation(odds ratio 1.08 per millimeter increase in diameter, 95%CI: 1.00-1.16, P = 0.05). There were also trends toward significance for increased left and right inferior PV sizes among those requiring repeat procedures.CONCLUSION Increased PV size predicts the need for repeat AF ablation, with each millimeter increase in PV diameter associated with an approximately 5%-10% increased risk of requiring repeat procedures. | Yaanik Desai Mathew R Levy Shahriar Iravanian Edward C Clermont Heval M Kelli Robert L Eisner Mikhael F El-Chami Angel R Leon David B Delurgio Faisal M Merchant | 2017 | World Journal of Cardiology2017，9，9： | 0 |
| 19 | Antinociceptive and Anti-inflammatory Activities of Methanol Extract of Ormosia coccinea (Aubl,) Jacks in vivo显示文摘 | Miguel Angel Diaz C. Lorena H. Cruz M. Mahabir P. Gupta Dionisio Olmedo Jose Luis Lopez-Perez Estela Guerrero De Leon Juan Antonio Moran-Pinzon | 2017 | Journal of Pharmacy and Pharmacology2017，5，6： | 0 |
| 20 | Prospective evaluation of health status, quality of life and clinical outcomes following implantable defibrillator generator exchange显示文摘BACKGROUND Little is known about health status and quality of life(QoL)after implantable cardioverter-defibrillator(ICD)generator exchange(GE).METHODS We prospectively followed patients undergoing first-time ICD GE.Serial assessments of health status were performed by administering the 36-Item Short Form Survey(SF-36).RESULTS Mean age was 67.5±14.3 years,left ventricle ejection fraction(LVEF)was 36.5%±15.0%and over 40%of the cohort had improved LVEF to>35%at the time of GE.SF-36 scores were significantly worse in physical/general health domains compared to domains of emotional/social well-being(P<0.001 for each comparison).Physical health scores were significantly worse among those with medical comorbidities including diabetes,chronic obstructive pulmonary disease and atrial fibrillation.Mean follow-up was 1.6±0.5 years after GE.Overall SF-36 scores remained stable across all domains during follow-up.Survival at 3 years post-GE was estimated at 80%.Five patients died during follow-up and most deaths were adjudicated as non-arrhythmic in origin.Four patients experienced appropriate ICD shocks after GE,three of whom had LVEF which remains impaired LVEF(i.e.,<35%)at the time of GE.CONCLUSION Patients undergoing ICD GE have significantly worse physical health compared to emotional/social well-being,which is associated with the presence of medical comorbidities.In terms of clinical outcomes,the incidence of appropriate shocks after GE among those with improvement in LVEF is very low,and most deaths post-procedure appear to be non-arrhythmic in origin.These data represent an attempt to more fully characterize the spectrum of QoL and clinical outcomes after GE. | Faisal M Merchant John Larson Leon Darghosian Paige Smith Soroosh Kiani Stacy Westerman Anand D.Shah David S.Hirsh Michael S.Lloyd Angel R.Leon Mikhael F.El-Chami | 2021 | Journal of Geriatric Cardiology2021，18，9： | 0 |
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