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| 1 | Inflammation in irritable bowel syndrome:Myth or newtreatment target?显示文摘Low-grade intestinal inflammation plays a key role in the pathophysiology of irritable bowel syndrome(IBS), and this role is likely to be multifactorial. The aim of this review was to summarize the evidence on the spectrum of mucosal inflammation in IBS, highlighting the relationship of this inflammation to the pathophysiology of IBS and its connection to clinical practice. We carried out a bibliographic search in Medline and the Cochrane Library for the period of January 1966 to December 2014, focusing on publications describing an interaction between inflammation and IBS. Several evidences demonstrate microscopic and molecular abnormalities in IBS patients. Understanding the mechanisms underlying low-grade inflammation in IBS may help to design clinical trials to test the efficacy and safety of drugs that target this pathophysiologic mechanism. | Emanuele Sinagra Giancarlo Pompei Giovanni Tomasello Francesco Cappello Gaetano Cristian Morreale Georgios Amvrosiadis Francesca Rossi Attilio Ignazio Lo Monte Aroldo Gabriele Rizzo Dario Raimondo | 2016 | World Journal of Gastroenterology2016，22，7： | 16 |
| 2 | Inflammation and Atherosclerosis显示文摘 | Peter Libby Paul M. Ridker Attilio Maseri | 2002 | Circulation: Journal of the American Heart Association2002，，9： | 11 |
| 3 | Review on microbiota and effectiveness of probiotics use in older显示文摘The aim of the present systematic review is to summarize the existing knowledge about the human microbiota in the elderly and the effects of probiotics in elderly population. The elderly subjects, compared to adult population, show a reduction in the diversity of the microbiota, characterized by a large interindividual variability, with lower numbers of Firmicutes, Bifidobacteria, Clostridium cluster XIV, Faecalibacterium Prausnitzii, Blautia coccoides-Eubacterium rectal and higher presence of Enterobacteriaceae and Bacteroidetes. These differences of the intestinal microbiota of the elderly may not necessarily be caused by aging, but they could be associated with the decline of the general state of health with malnutrition and with increased need for medication, such as antibiotics and nonsteroidal antiinflammatory drugs, situations that occur frequently in the elderly. Differences have been demonstrated in the composition of the microbiota between healthy elderly subjects and hospitalized or institutionalized elderly subjects. These findings which further indicates that the living conditions, health status, nutrition and drugs have a significant effect on the composition of the microbiota. According to the available knowledge, the use of probiotics is safe and could represent an useful intervention to prevent or treat antibioticassociated diarrhea, in addition to reducing the severity of symptoms, other than to help the management of constipation. | Mariangela Rondanelli Attilio Giacosa Milena Anna Faliva Simone Perna Francesca Allieri Anna Maria Castellazzi | 2015 | World Journal of Clinical Cases2015，3，2： | 10 |
| 4 | Myocardial Cell Death in Human Diabetes显示文摘 | Andrea Frustaci Jan Kajstura Cristina Chimenti Igor Jakoniuk Annarosa Leri Attilio Maseri Bernardo Nadal-Ginard Piero Anversa | 2000 | Circulation Research: Journal of the American Heart Association2000，，12： | 4 |
| 5 | Efficacy and safety of endoscopic papillary balloon dilation for the removal of bile duct stones: Data from a “real-life” multicenter study on Dilation-Assisted Stone Extraction显示文摘AIM To report data on Dilation-Assisted Stone Extraction(DASE) use in clinical practice and its efficacy and safety trough three Italian referral centers for biliopancreatic diseases treatment. METHODS From January 2011 to December 2015 we collected data on 120 patients treated with DASE. Technical success was obtained when the endoscopist was able to place the balloon trough the papilla inflating the balloon until the final diameter for an adequate time(at least 30 s). Clinical success was obtained after complete stone removal(no remaining stones were visible at the cholangiogram).RESULTS Forty-nine male(40.8%) and 71 female(59%) were enrolled. The mean age was 67.8 years ± 15.7. The mean common bile duct(CBD) dilation was 19.2 mm± 3.9 and the mean size of stones 15.8 ± 2.9. DASE was applied as first approach in 38%(62% after initial failure of stones extraction). Technical and clinical success was of 91% and 87% respectively. In those in which DASE failed alternative treatment were adopted. After DASE 18% of patients experienced a complication(bleeding 9%, pancreatitis 8%, perforation 0.8%). At univariable analysis, elective endoscopic retrograde cholangiopancreatography(P = 0.031), DASE as first approach(P = 0.032), and cannulation of major papilla followed by guidewire insertion(P = 0.004) were related to low risk of complications. Pre-cut was related to an increased risk of complications(P = 0.01). CONCLUSION DASE allowed a higher first-session success rate and can be consider a valid alternative to endoscopic sphincterotomy not only for bigger CBD stones. | Roberto Di Mitri Filippo Mocciaro Socrate Pallio Giulia Maria Pecoraro Andrea Tortora Claudio Zulli Simona Attardo Attilio Maurano | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，18： | 3 |
| 6 | Structural health monitoring of bridges in the State of Connecticut显示文摘A joint effort between the Connecticut Department of Transportation and the University of Connecticut has been underway for more than 20 years to utilize various structural monitoring approaches to assess different bridges in Connecticut.This has been done to determine the performance of existing bridges,refine techniques needed to evaluate different bridge components,and develop approaches that can be used to provide a continuous status of a bridge's structural integrity.This paper briefly introduces the background of these studies,with emphasis on recent research and the development of structural health monitoring concepts.This paper presents the results from three different bridge types:a post-tensioned curved concrete box girder bridge,a curved steel box-girder bridge,and a steel multi-girder bridge.The structural health monitoring approaches to be discussed have been successfully tested using field data collected during multi-year monitoring periods,and are based on vibrations,rotations and strains.The goal has been to develop cost-effective strategies to provide critical information needed to manage the State of Connecticut's bridge infrastructure. | Chengyin Liu Joshua Olund Alan Cardini Paul D'Attilio Eric Feldblum John DeWolf | 2008 | Earthquake Engineering and Engineering Vibration2008，7，4： | 3 |
| 7 | Cloning and molecular analysis of structural genes involved in flavonoid and stilbene biosynthesis in grape (Vitis vinifera L.)显示文摘 | Francesca Sparvoli Cathie Martin Attilio Scienza Giuseppe Gavazzi Chiara Tonelli | 1994 | Plant Molecular Biology1994，，5： | 3 |
| 8 | Persistent Activation of Nuclear Factor Kappa-B Signaling Pathway in Patients With Unstable Angina and Elevated Levels of C-Reactive Protein显示文摘 | Giovanna Liuzzo Matteo Santamaria Luigi M. Biasucci Michela Narducci Valeria Colafrancesco Annalisa Porto Salvatore Brugaletta Michela Pinnelli Vittoria Rizzello Attilio Maseri Filippo Crea | 2007 | Journal of the American College of Cardiology2007，，2： | 2 |
| 9 | Coronavirus disease 2019 (COVID-19) and prosthetic heart valve: An additional coagulative challenge显示文摘Dear editor,A new infectious disease outbreak,caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),is now spreading all around the world.[1]One of the most critical understandings of the current pandemic of the coronavirus disease 2019(COVID-19)focuses on an imbalanced coagulation status.Based on the current evidence,we can divide the COVID-19-related hypercoagulable state into two categories[2]:patients without other pre-existing indications for anticoagulant therapy who develop a state of hypercoagulability linked to SARS-CoV-2 infection especially during the cytokine storm phase,and patients already on anticoagulation in whom we have to reevaluate their drug choices,dosages,and pharmacokinetics.At the same time,recent literature recommends the use of heparin in severe SARS-CoV-2 infection,both as thromboembolic prophylaxis and as an anticoagulant therapy,in light of possible anti-infl ammatory and antiviral mechanisms and less pharmacological interferences.[3]This indication should be adopted in all patients except for those with prosthetic heart valves,in whom vitamin K antagonists continue to remain the drug of choice.[4]In this subgroup of patients,strict monitoring of PT-INR is required to maintain the therapeutic range.The purpose of this article is to underline the need for good quality evidence regarding the management of this high-risk category of the patient population. | Attilio Allione Jacopo Davide Giamello Sara Bernardi Giulia Paglietta Giulia Lucia Massimina Cavalot Luca Alessio Dutto Daniela Caruso Andrea Tortore Giuseppe Lauria | 2020 | World Journal of Emergency Medicine2020，11，4： | 2 |
| 10 | Obstruction of Mechanical Mitral Prostheses: Analysis of Pathologic Findings显示文摘 | Nicola Vitale Attilio Renzulli Lucio Agozzino Alessio Pollice Nicola Tedesco Luigi de Luca Tupputi Schinosa Maurizio Cotrufo | 1997 | The Annals of Thoracic Surgery1997，，4： | 2 |
| 11 | Effect of temperature and nitrogen concentration on the growth and lipid content of Nannochloropsis oculata and Chlorella vulgaris for biodiesel production显示文摘 | Attilio Converti Alessandro A. Casazza Erika Y. Ortiz Patrizia Perego Marco Del Borghi | 2009 | Chemical Engineering & Processing: Process Intensification2009，，6： | 2 |
| 12 | Contrast-Enhanced Ultrasound Imaging of Intraplaque Neovascularization in Carotid Arteries显示文摘 | Stefano Coli Marco Magnoni Giuseppe Sangiorgi Massimiliano M. Marrocco-Trischitta Giulio Melisurgo Alessandro Mauriello Luigi Spagnoli Roberto Chiesa Domenico Cianflone Attilio Maseri | 2008 | Journal of the American College of Cardiology2008，，3： | 2 |
| 13 | Biological removal of phosphorus from wastewaters by alternating aerobic and anaerobic conditions显示文摘 | Attilio Converti Mauro Rovatti Marco Del Borghi | 1994 | Water Research1994，，1： | 1 |
| 14 | Vitamin D Serum Levels and Markers of Asthma Control in Italian Children显示文摘 | Iolanda Chinellato Michele Piazza Marco Sandri Diego Peroni Giorgio Piacentini Attilio L. Boner | 2011 | The Journal of Pediatrics2011，，3： | 1 |
| 15 | Cloning and molecular analysis of structural genes involved in flavonoid and stilbene biosynthesis in grape ( Vitis vinifera L.)显示文摘 | Francesca Sparvoli Cathie Martin Attilio Scienza Giuseppe Gavazzi Chiara Tonelli | 1994 | Plant Molecular Biology1994，，5： | 1 |
| 16 | Benefits of drug-eluting stents as compared to bare metal stent in ST-segment elevation myocardial infarction: Four year results of the P aclit A xel or S irolimus- E luting stent vs bare metal stent in primary angiOplasty (PASEO) randomized trial显示文摘 | Emilio Di Lorenzo Rosario Sauro Attilio Varricchio Michele Capasso Tonino Lanzillo Fiore Manganelli Ciro Mariello Francesco Siano Maria Rosaria Pagliuca Giovanni Stanco Giuseppe Rosato Giuseppe De Luca | 2009 | American Heart Journal2009，，： | 1 |
| 17 | Desalinated water production at LNG terminals 显示文摘 | Attilio A | 1983 | Desalination1983，45，3： | 1 |
| 18 | The use of an oral contraceptive containing estradiol valerate and dienogest before office operative hysteroscopy: a feasibility study显示文摘 | Giuseppe Bifulco Attilio Di Spiezio Sardo Nicoletta De Rosa Elena Greco Marialuigia Spinelli Costantino Di Carlo Giovanni A. Tommaselli Carmine Nappi | 2012 | Gynecological Endocrinology2012，，12： | 1 |
| 19 | Effect of temperature and nitrogen concentration on the growth and lipid content of Nannochloropsis oculata and Chlorella vulgaris for biodiesel production显示文摘 | Attilio Converti Alessandro A. Casazza Erika Y. Ortiz Patrizia Perego Marco Del Borghi | 2009 | Chemical Engineering & Processing: Process Intensification2009，，6： | 1 |
| 20 | Effects of physical activity in Parkinson's disease: A new tool for rehabilitation显示文摘Parkinson's disease(PD) is a common neurodegenerative disease characterized by bradykinesia, tremor, rigidity, and postural instability. Motor disorders are composite and combined, adversely affecting the patient's health. Tremor and rigidity are correlated with worsening manual dexterity as well as postural changes such as akinesia and camptocormia. Moreover, gait alteration as well as postural instability, with consequent impairment in balance, increase the risk of falls. It is well known that these symptoms respond poorly to pharmacologic therapy in PD patients. Physical therapy is the most effective non-pharmacological aid to PD patients. Available data in the literature indicate that any rehabilitation protocol has to focus on: cognitive movement strategies, cueing strategies, and improved physical capacity and balance. Different training programs for PD patients have been designed and evaluated but only specific training strategies, tailored and individualized for each patient, may produce improvements in gait speed and stride length, decrease motor and balance symptoms and improve quality of life. Furthermore, aerobic training may improve muscle trophism, strength and mobility. It seems reasonable to state that tailoredphysical activity is a valid tool to be included in the therapeutic program of PD patients, considering that this approach may ameliorate the symptoms as well as the overall physical incapacity, reduce the risk of falls and injuries, and ultimately improve quality of life. | Paolo Borrione Eliana Tranchita Pierpaolo Sansone Attilio Parisi | 2014 | World Journal of Methodology2014，4，3： | 1 |
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