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1Practice guidelines for the pathological diagnosis of primary liver cancer: 2015 update显示文摘In 2010, a panel of Chinese pathologists reported the first expert consensus for the pathological diagnosis of primary liver cancers to address the many contradictions and inconsistencies in the pathological characteristics and diagnostic criteria for PLC. Since then considerable clinicopathological studies have been conducted globally, prompting us to update the practice guidelines for the pathological diagnosis of PLC. In April 18, 2014, a Guideline Committee consisting of 40 specialists from seven Chinese Societies(including Chinese Society of Liver Cancer, Chinese Anti-Cancer Association; Liver Cancer Study Group, Chinese Society of Hepatology, Chinese Medical Association; Chinese Society of Pathology, Chinese Anti-Cancer Association; Digestive Disease Group, Chinese Society of Pathology, Chinese Medical Association; Chinese Society of Surgery, Chinese Medical Association; Chinese Society of Clinical Oncology, Chinese Anti-Cancer Association; Pathological Group of Hepatobiliary Tumor and Liver Transplantation, Chinese Society of Pathology, Chinese Medical Association) was created for the formulation of the first guidelines for the standardization of the pathological diagnosis of PLC, mainly focusing on the following topics: gross specimen sampling, concepts and diagnostic criteria of small hepatocellular carcinoma(SHCC), microvascular invasion(MVI), satellite nodules,and immunohistochemical and molecular diagnosis. The present updated guidelines are reflective of current clinicopathological studies, and include a novel 7-point baseline sampling protocol, which stipulate that at least four tissue specimens should be sampled at the junction of the tumor and adjacent liver tissues in a 1:1 ratio at the 12, 3, 6 and 9 o'clock reference positions. For the purposes of molecular pathological examination, at least one specimen should be sampled at the intratumoral zone, but more specimens should be sampled for tumors harboring different textures or colors. Specimens should be sampled at both adjacent and distant peritumoral liver tissues or the tumor margin in order to observe MVI, satellite nodules and dysplastic foci/nodules distributed throughout the background liver tissues. Complete sampling of whole SHCC ≤ 3 cm should be performed to assess its biological behavior, and in clinical practice, therapeutic borders should be also preserved, even in SHCC. The diagnostic criteria of MVI and satellite nodules, immunohistochemical panels, as well as molecular diagnostic principles, such as clonal typing, for recurrent HCC and multinodule HCC were also proposed and recommended. The standardized process of pathological examination is aimed at ensuring the accuracy of pathological PLC diagnoses as well as providing a valuable frame of reference for the clinical assessment of tumor invasive potential, the risk of postoperative recurrence, long-term survival, and the development of individualized treatment regimens. The updated guidelines could ensure the accuracy of pathological diagnoses of PLC, and provide a valuable frame of reference for its clinical assessment.Wen-Ming Cong Hong Bu Jie Chen Hui Dong Yu-Yao Zhu Long-Hai Feng Jun Chen 2016World Journal of Gastroenterology2016,22,42:81
2Effect of hepatitis C virus infection on expression of several cancer-associated gene products in hepatocellular carcinoma显示文摘NTRODUCTIONOurpreviousstudiesbyseroepidemiological,molecularepidemiologicalandimmunopathologicalmethodshaverevealedthathepa...YANG Jian Min, WANG Rong Quan, BU Bao Guo, ZHOU Zi Cheng, FANG Dian Chun and LUO Yuan Hui 1999World Journal of Gastroenterology1999,5,1:42
3Acacetin protects against cerebral ischemia-reperfusion injury via the NLRP3 signaling pathway显示文摘Acacetin(5,7-dihydroxy-4′-methoxyflavone), a potential neuroprotective agent, has an inhibitory effect on lipopolysaccharide-induced neuroinflammatory reactions. However, whether acacetin has an effect on inflammatory corpuscle 3(NLRP3) after cerebral ischemia-reperfusion injury has not been fully determined. This study used an improved suture method to establish a cerebral ischemia-reperfusion injury model in C57BL/6 mice. After ischemia with middle cerebral artery occlusion for 1 hour, reperfusion with intraperitoneal injection of 25 mg/kg of acacetin(acacetin group) or an equal volume of saline(0.1 mL/10 g, middle cerebral artery occlusion group) was used to investigate the effect of acacetin on cerebral ischemia-reperfusion injury. Infarct volume and neurological function scores were determined by 2,3,5-triphenyltetrazolium chloride staining and the Zea-Longa scoring method. Compared with the middle cerebral artery occlusion group, neurological function scores and cerebral infarction volumes were significantly reduced in the acacetin group. To understand the effect of acacetin on microglia-mediated inflammatory response after cerebral ischemia-reperfusion injury, immunohistochemistry for the microglia marker calcium adapter protein ionized calcium-binding adaptor molecule 1(Iba1) was examined in the hippocampus of ischemic brain tissue. In addition, tumor necrosis factor-α, interleukin-1β, and interleukin-6 expression in ischemic brain tissue of mice was quantified by enzyme-linked immunosorbent assay. Expression of Iba1, tumor necrosis factor-α, interleukin-1β and interleukin-6 was significantly lower in the acacetin group compared with the middle cerebral artery occlusion group. Western blot assay results showed that expression of Toll-like receptor 4, nuclear factor kappa B, NLRP3, procaspase-1, caspase-1, pro-interleukin-1β, and interleukin-1β were significantly lower in the acacetin group compared with the middle cerebral artery occlusion group. Our findings indicate that acacetin has a protective effect on cerebral ischemia-reperfusion injury, and its mechanism of action is associated with inhibition of microglia-mediated inflammation and the NLRP3 signaling pathway.Juan Bu Shen Shi Hui-Qin Wang Xiao-Shan Niu Zong-Feng Zhao Wei-Dong Wu Xiao-Ling Zhang Zhi Ma Yan-Jun Zhang Hui Zhang Yi Zhu 2019Neural Regeneration Research2019,14,4:22
4MAX2 Affects Multiple Hormones to Promote Photornorphogenesis显示文摘Ubiquitin-26S proteasome 系统(不间断电源) 被显示了在轻、调整荷尔蒙的植物生长和开发起中央作用。以前,我们显示出那 MAX2, F 盒子蛋白质,断然响应光调整 photomorphogenic 开发的方面。然而, MAX2 怎么控制这些回答,仍然是未知的。这里,我们证明 MAX2 相对地调整 GA 和骆驼毛的织物生合成响应光优化种子萌芽。Doseresponse 曲线证明 max2 种子对 GA 弱敏并且对在种子萌芽回答的骆驼毛的织物过分敏感。RTPCR 试金证明 GA biosynthetic 基因的表示是下面调整的,当 GA 分解代谢的基因的表示在 max2 种子与相比是起来调整的时野类型。有趣地,两骆驼毛的织物 biosynthetic 的表示和分解代谢的基因在 max2 种子与相比是起来调整的野类型。有一个植物生长素运输禁止者的处理, NPA,证明在 max2 幼苗的那增加的植物生长素运输在光下面贡献长胚轴显型。而且,轻发信号的显型被限制为 max2 作为在 strigolactone 小径, max1, max3,和 max4 的 biosynthetic 异种,没在种子萌芽和幼苗 de 青白化显示任何缺点与相比野类型。一起拿,这些数据建议 MAX2 调制多重荷尔蒙小径影响 photomorphogenesis。Hui Shen Ling Zhu Qing-Yun Bu Enamul Huq 2012Molecular Plant2012,5,3:14
5Synergistically Directed Assembly of Aromatic Stacks Based Metal-Organic Frameworks by Donor-Acceptor and Coordination Interactions显示文摘A synergistically directed assembly approach to distinctive metal-organic frameworks utilizing both donor-acceptor (D-A) interaction from aromatic systems and coordination interactions is presented.Based on such an approach,the coronene-tpt (tpt =2,4,6-tri(4-pyridyl)-1,3,5-triazine) stacks based coronene-MOF-1-4 have been successfully fabricated.Their structural discrepancies with coroneneabsent control products,1'-4',illustrate clearly the significance of coronene-tpt based D-A interactions in these architectures.All these coronene-MOFs contain varied coronene-tpt stacks as organic secondary building blocks (SBUs),which are closely interrelated with the coordination based framework structures.Moreover,porous coronene-MOF-1 and-2 exhibit high physicochemical stability and significant light hydrocarbons storage and separation performances.Xi Wang Ying Zhang Ze Chang Hui Huang Xiao-Ting Liu Jialiang Xu Xian-He Bu 2019Chinese Journal of Chemistry2019,37,9:11
6Completely video-assisted thoracoscopic lobectomy versus open lobectomy for non-small cell lung cancer greater than 5 cm:a retrospective study显示文摘背景完全帮助录像的 thoracoscopic Iobectomy 是为早阶段的 non-small-cell 肺癌症(NSCLC ) 的合理治疗在场的 .At,为这个过程的指示是阶段 la 和 Ib 外部肺癌症((<-)5 厘米) ;为更大的肿瘤,然而,这种外科的技术是否是可比较的开 Iobectomy.This 学习试图评估 thoracoscopic Iobectomy 的安全,完全性,和功效,仍然保持争论,并且在我们的 center.In 为 non-small-cell 肺癌症的治疗经历了 Iobectomy 当肿瘤的直径比从2001年5月的 5 cm.Methods 大到4月2011,802日病人时,为 non-small-cell 肺癌症的治疗把这种技术与开的 Iobectomy 作比较 133 个病人,肿瘤Bu Liang Li Yun Yang Fan Zhao Hui Jiang Guan-chao Li Jian-feng Liu Jun Wang Jun 2012Chinese Medical Journal2012,,3:10
7Crop rotation-dependent yield responses to fertilization in winter oilseed rape(Brassica napus L.)显示文摘Differences in soil physical, chemical and biological properties between paddy–upland and continuous upland rotations will influence nutrient relations and crop growth. With the aim of estimating rapeseed yield performance in response to fertilization in rice–rapeseed(RR) and cotton–rapeseed(CR) rotations, on-farm experiments were conducted at 70 sites across Hubei province, central China. The economically optimal fertilizer rates of winter oilseed rape in different rotations were determined. Field experiments showed that previous crops significantly influenced seed yields. Without N fertilization,seed yields were significantly lower for the RR rotation than for the CR rotation. The average yield increase ratio and agronomic efficiency associated with nitrogen(N)fertilization in the RR rotation were 96.6% and 6.56 kg kg- 1, significantly higher than those in the CR rotation. No seed yield differences were detected between the two rotations under phosphorus(P) and potassium(K) fertilization. In contrast to the CR rotation, N fertilizer played a more vital role in maintaining high seed yields in the RR rotation owing to the lower indigenous soil N supply. Compared with local N fertilizer recommendation rates for the RR rotation, on average an additional 18 kg N ha- 1was recommended according to the economically optimal N fertilizer rate(EONFR). In contrast, the EONFR was 14 kg N ha- 1lower than the locally recommended N fertilizer rate for the CR rotation. There were no differences between the two rotations for the average economically optimal P and K fertilization rates. Consequently, the average EONFR of winter oilseed rape could be reduced if cotton rather than rice preceded the winter oilseed rape.Tao Ren Hui Li Jianwei Lu Rongyan Bu Xiaokun Li Rihuan Cong Mingxing Lu 2015The Crop Journal2015,3,5:8
8Upconversion nano-photosensitizer targeting into mitochondria for cancer apoptosis induction and cyt c fluorescence monitoring显示文摘反应的氧种类(mitoROS ) 玩的 mitochondrial 的混乱在癌症房间 apoptosis 的一个主要角色。这里,我们设计了 core/shell-structured 有由 photosensitizer (PS ) 涂的核心合并了的做 lanthanide 的 upconversion nanoparticle (UCNP ) 的指向线粒体的基于 upconversion 的使 nano 具有感光性(TPP-UC (PS )) 稠密的硅石壳。有外部在红外线附近的激光(NIR ) 的后面的照耀,在引起为激活的基于 upconversion 的光力学的治疗(UC 太平洋夏季时间) 胀大的严肃的 mitochondrial 矩阵的线粒体的 TPP-UC (PS ) ,和细胞色素 c (cyt c ) 的动员响应增加的 mitoROS 被放大。明确地,这包含 heme cyt c 能被改变 TPP-UC (PS ) s upconversion 光信号(UCL ) 监视,它可以便于在里面为 apoptosis 研究的 cyt c 的 situ 察觉。作为概念的一个证明,我们的设计 TPP-UC (PS ) 可以为在 NIR 刺激下面控制癌症房间 apoptosis 并且为用动态 UCL 学习 apoptosis 提供重要机会,它被本地 cyt c 影响。Yanyan Liu Jiawen Zhang Changjing Zuo Zhen Zhang Dalong Ni Chen Zhang Jing Wang Hui Zhang Zhenwei Yao Wenbo Bu 2016Nano Research2016,9,11:8
9Efficacy and safety of Yunxiangjing derived from Chinese herbal medicine administered as an enema in the management of acute radiation-induced proctitis in patients with pelvic malignancy显示文摘OBJECTIVE: To assess the efficacy and safety of Yunxiangjing(YXJ), derived from Chinese herbal medicine, in the management of acute radiation-induced proctitis(ARIP) in patients with pelvic malignancy.METHODS: Forty-eight patients with grade 2 ARIP were administered YXJ as an enema(1∶30 dilution)for 2 weeks and followed up for 2 years. All were assessed for response and ARIP grade. Quality of life(QOL) was assessed with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30.RESULTS: Of the 48 patients, six(12.5%) achieved complete remission of ARIP and 28(58.3%) showed a decrease from grade 2 to grade 1 ARIP. No patient experienced a grade ≥3 toxicity. At the end of radiotherapy, patients showed significant improvements in QOL(P < 0.05). Two years after treatment, 46 patients showed no late toxicity, with only two experiencing grade 1 late toxicity.CONCLUSION: YXJ can be used as an enema to manage acute radiation-induced proctitis in cancer patients undergoing radiotherapy. These findings suggest that YXJ enema may be an alternative treatment of ARIP.Tang Huaying Huang Yinchun Mo Xingneng Yi Guisheng Wen Hui Guo Zhen Feng Kaihua Liu Yin Bu Qing Jiang Wei 2016Journal of Traditional Chinese Medicine2016,36,1:7
10DOES INVESTOR SENTIMENT PREDICT STOCK RETURNS? THE EVIDENCE FROM CHINESE STOCK MARKET显示文摘BU Hui PI Li 2014Journal of Systems Science & Complexity2014,27,1:7
11Comparison of the autofluorescence bronchoscope and the white light bronchoscope in airway examination显示文摘Background and Objective: The sensitivity and accuracy of white light bronchoscopy (WLB) in airway examination are low. Autofluorescence bronchoscope (AFB) can determine early lesions in bronchial mucosa more sensitively, but it has seldom performed in China. To assess the clinical value of the AFB in airway examination, we compared the sensitivity and specificity of the AFB and WLB in detecting cancer of the airway mucosa. Methods: Between September 2009 and May 2010, bronchoscope examinations using both the AFB and WLB were performed on 136 patients, 95 men and 41 women with a median age of 61.5 years (ranged from 25 to 84 years). There were 46 lesions located in the central airway, 84 in the peripheral lung parenchyma, and 6 in the mediastinal region. All patients received local and general anesthesia and were subsequently examined with the WLB and AFB in tandem. All procedures were completed safely. Abnormal visual findings were recorded, and biopsies of the affected regions were collected for pathologic examination. Results: Of 241 regions sampled for biopsy, 76 sites contained malignant lesions, whereas 165 sites contained benign lesions. The AFB detected 72 of the 76 malignant lesions, but the WLB detected only 50. The sensitivities of the AFB and WLB were 94.7% and 65.8%, respectively, and the specificities were 57.0% and 83.6%, respectively. The negative predictive values of the AFB and WLB were 95.9% and 84.1%, respectively. Conclusions: The AFB is more sensitive than the WLB in detecting cancerous lesions in the mucosa, and is an effective airway examination.Yun Li Xiao Li Xi-Zhao Sui Liang Bu Zu-Li Zhou Fan Yang Yan-Guo Liu Hui Zhao Jian-Feng Li Jun Liu Guan-Chao Jiang Jun Wang 2010Chinese Journal of Cancer2010,29,12:7
12Application of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of mediastinal lesions显示文摘背景 Mediastinal 损害经常是困难的因为纵隔的唯一的解剖位置,在临床的实践诊断,它广泛地做在肺癌症和 mediastinal 淋巴节点阶段的诊断的指导超声的 transbronchial 针渴望是的 endobronchial 的活体检视 difficult.The 价值的性能 accepted.However ,很少研究在 endobronchial 的价值上被进行了在诊断和 differenti 的指导超声的 transbronchialZHAO Hui WANG Jun ZHOU Zu-li LI Yun BU Liang YANG Fan SUI Xi-zhao CHEN Ke-zhong LI Xiao LIU Jun LI Jian-feng JIANG Guan-chao 2011Chinese Medical Journal2011,,23:6
13CNT@MnO_(2) composite ink toward a flexible 3D printed micro-zinc-ion battery显示文摘Flexible energy storage devices have played a significant role in multiscenario applications,while flexible zinc-ion batteries(ZIBs),as an essential branch,have developed rapidly in recent years.Three-dimensional(3D)printing is an extremely advanced technology to design and modify the structure of batteries and provides unlimited possibilities for the diversified development of energy storage equipment.Herein,by utilizing 3D printing technology,carbon nanotube(CNT)is coated by MnO_(2) to form a flexible CNT@MnO_(2) ink as a cathode for flexible aqueous micro-ZIBs for the first time and zinc powder ink is used as an anode due to its high flexibility and bendability.The Zn//CNT@MnO_(2) flexible battery shows a stable capacity of 63μAh cm^(−2) at 0.4mA cm^(−2).When the battery is bent in different states,the maximum capacity loss compared with the initial value is only 2.72%,indicating its stability.This study shows the potential of 3D printing technology in the development of flexible manganese-based ZIBs.Yujin Ren Fanbo Meng Siwen Zhang Bu Ping Hui Li Bosi Yin Tianyi Ma 2022Carbon Energy2022,4,3:5
14The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus.Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang 2016Science China(Life Sciences)2016,59,9:5
15Treatment results and prognostic factors of patients undergoing postoperative radiotherapy for laryngeal squamous cell carcinoma显示文摘Postoperative radiotherapy (PRT) is widely advocated for patients with squamous cell carcinomas of the head and neck that are considered to be at high risk of recurrence after surgical resection. The aims of this study were to evaluate the treatment outcomes of PRT for patients with laryngeal carcinoma and to identify the value of several prognostic factors. We reviewed the records of 256 patients treated for laryngeal squamous cell carcinoma between January 1993 and December 2005. Disease-free survival (DFS) and overall survival (OS) were estimated using the Kaplan-Meier method. Log-rank test was employed to identify significant prognostic factors for DFS and OS. The Cox proportional hazards model was applied to identify covariates significantly associated with the aforementioned endpoints. Our results showed the 3-, 5-, and 10-year DFS for all patients were 69.9%, 59.5%, and 34.9%, respectively. The 3-, 5-, and 10-year OS rates were 80.8%, 68.6%, and 38.8%, respectively. Significant prognostic factors for both DFS and OS on univariate analysis were grade, primary site, T stage, N stage, overall stage, lymph node metastasis, overall treatment times of radiation, the interval between surgery and radiotherapy, and radiotherapy equipment. Favorable prognostic factors for both DFS and OS on multivariate analysis were lower overall stage, no cervical lymph node metastasis, and using 60Co as radiotherapy equipment. In conclusion, our data suggest that lower overall stage, no cervical lymph node metastasis, and using 60Co as radiotherapy equipment are favorable prognostic factors for DFS and OS and that reducing the overall treatment times of radiation to 6 weeks or less and the interval between surgery and radiotherapy to less than 3 weeks are simple measures to remarkably improve treatment outcome.Ting Jin Wei-Han Hu Li-Bing Guo Wen-Kuan Chen Qiu-Li Li Hui Lin Xiu-Yu Cai Nan Ge Rui Sun Si-Yi Bu Xin Zhang Meng-Yao Qiu Wei Zhang Su Luo Yi-Xin Zhou 2011Chinese Journal of Cancer2011,30,7:5
16DeST 3.0:A new-generation building performance simulation platform显示文摘Buildings contribute to almost 30%of total energy consumption worldwide.Developing building energy modeling programs is of great significance for lifecycle building performance assessment and optimization.Advances in novel building technologies,the requirements of high-performance computation,and the demands for multi-objective models have brought new challenges for building energy modeling software and platforms.To meet the increasing simulation demands,DeST 3.0,a new-generation building performance simulation platform,was developed and released.The structure of DeST 3.0 incorporates four simulation engines,including building analysis and simulation(BAS)engine,HVAC system engine,combined plant simulation(CPS)engine,and energy system(ES)engine,connected by air loop and water loop balancing iterations.DeST 3.0 offers numerous new simulation features,such as advanced simulation modules for building envelopes,occupant behavior and energy systems,cross-platform and compatible simulation kernel,FMI/FMU-based co-simulation functionalities,and high-performance parallel simulation architecture.DeST 3.0 has been thoroughly evaluated and validated using code verification,inter-program comparison,and case-study calibration.DeST 3.0 has been applied in various aspects throughout the building lifecycle,supporting building design,operation,retrofit analysis,code appliance,technology adaptability evaluation as well as research and education.The new generation building simulation platform DeST 3.0 provides an efficient tool and comprehensive simulation platform for lifecycle building performance analysis and optimization.Da Yan Xin Zhou Jingjing An Xuyuan Kang Fan Bu Youming Chen Yiqun Pan Yan Gao Qunli Zhang Hui Zhou Kuining Qiu Jing Liu Yan Liu Honglian Li Lei Zhang Hong Dong Lixin Sun Song Pan Xiang Zhou Zhe Tian Wenjie Zhang Ruhong Wu Hongsan Sun Yu Huang Xiaohong Su Yongwei Zhang Rui Shen Diankun Chen Guangyuan Wei Yixing Chen Jinqing Peng 2022Building Simulation2022,15,11:5
17An analytic solution describing the visco-elastic deformation of coal pillars in room and pillar mine显示文摘Coal pillar deformation is typically nonlinear and time-dependent. The accurate prediction of this defor- mation has a vital importance for the successful implementation of mining techniques. These methods have proven very important as a way to excavate coal resources from under buildings, railways, or water bodies. Elastic and visco-elastic theory are employed with a Maxwell model to formulate an analytic solution for displacement of coal pillars in room and pillar mine. These results show that the visco-elastic solution adequately predicts the coal pillar deformation over time. We conclude that the visco-elastic solution can predict the coal pillar and roadway displacement from the measured geological parameters of the conditions in situ. Furthermore, this method would be useful for mine design, coal pillar support optimization, ground subsidence prediction, and coal pillar stability analysis.Li Qiang XU Hui BU Wankui Zhao Guozhen 2011Mining Science and Technology2011,21,6:5
18Board affiliation and pay gap显示文摘This paper examines the effects of board affiliation on the corporate pay gap.Using a sample of Chinese listed firms from 2005 to 2011, we find that boards with a greater presence of directors appointed by block shareholders have lower pay gaps. Furthermore, the governance effects of board affiliation with and without pay are distinguished. The empirical results show that board affiliation without pay is negatively related to the pay gap, while board affiliation with pay is positively related to the pay gap. Overall, the results shed light on how block shareholders affect their companies' pay gaps through board affiliation.Shenglan Chen Hui Ma Danlu Bu 2014China Journal of Accounting Research2014,,2:4
19The Role of HBx Gene Mutations in PLA2R Positive Hepatitis-B-associated Membranous Nephropathy显示文摘China is a higher-intermediate hepatitis B virus(HBV)endemicity country,and HBV is among the most important infectious diseases[1,2].Hepatitis-Bassociated glomerulonephritis(HBV-GN)is also one of the main forms of secondary kidney diseases seen in China[3].The main pathological type is hepatitis-Bassociated membranous nephropathy(HBV-MN).In the recent years,it has been found that human renal podocyte membrane M-type phospholipase 2 receptor(PLA2R)is the main autoantigen in idiopathic membranous nephropathy(IMN)[4].At present,it is found that PLA2 R and its antibodies are.DONG Hui XU Yan XU Ting SUN Jing Yi BU Quan Dong WANG Yan Fei CHE Lin ZHAO Long JIANG Wei 2020Biomedical and Environmental Sciences2020,33,4:3
20Correlates of Condom-use Self-efficacy on the EPPM-based Integrated Model among Chinese College Students显示文摘Objective To explore the predictors of condom-use self-efficacy in Chinese college students according to the extended parallel process model(EPPM)-based integrated model.Methods A total of 3,081 college students were anonymously surveyed through self-administered questionnaires in Guangzhou and Harbin,China.A structural equation model was applied to assess the integrated model.Results Among the participants,1,387(46.7%)were male,1,586(53.3%)were female,and the average age was 18.6 years.The final integrated model was acceptable.Apart from the direct effect(r=0.23),perceived severity had two indirect effects on condom-use self-efficacy through the attitude to HIV education(r=0.40)and intention to engage in premarital sex(r=-0.16),respectively.However,the perceived susceptibility mediated through the intention to engage in premarital sex(intent-to-premarital-sex)had a poor indirect impact on condom-use self-efficacy(total effect was-0.06).Furthermore,attitude toward HIV health education(r=0.49)and intent-to-premarital-sex(r=-0.31)had a strong direct effect on condom-use self-efficacy.In addition,male students perceived higher susceptibility,stronger intent-to-premarital-sex,and lower condom-use self-efficacy than female students.Conclusion The integrated model may be used to assess the determinants of condom-use self-efficacy among Chinese college students.Future research should focus on raising the severity perception,HIV-risk-reduction motivation,and the premarital abstinence intention among college students.Furthermore,considering the gender differences observed in the present survey,single-sex HIV education is required in school-based HIV/sex intervention.JIN Shan Shan BU Kai CHEN Fang Fang XU Hui Fang LI Yi ZHAO Dong Hui XU Fang LI Jing Yan HAN Meng Jie WANG Ning WANG Lu 2017Biomedical and Environmental Sciences2017,30,2:3
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