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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)显示文摘 | Bentley SD Chater KF Cerdeno-Tarraga AM Challis GL Thomson NR James KD Harris DE Quail MA Kieser H Harper D Bateman A Brown S Chandra G Chen CW Collins M Cronin A Fraser A Goble A Hidalgo J Hornsby T Howarth S Huang CH Kieser T Larke L Murphy L Oliver K O | | 0，，： | 1 |
| 3 | Road transport conditions of slaughter cattle: Effects on the prevalence of dark, firm and dry beef显示文摘 | WARREN L A MANDELL I B BATEMAN K G | 2010 | Canadian Journal of Animal Science2010，90，4： | 1 |
| 4 | The pa-raspinal sacrospinalis-splitting approach to the lumbar spine显示文摘 | Wiltse L L Bateman J G Hutchinson R H | 1968 | J Bone Joint Surg Am1968，50，5： | 1 |
| 5 | The paraspinal sa- cmspinalis- splitting approach to the lumbar spine 显示文摘 | Wiltse L L Bateman J G Hutchinson R H | 1968 | J Bone Joint Surg Am1968，50，： | 1 |
| 6 | The Pfam protein families database 显示文摘 | Punta M Coggill P C Eberhardt R Y Mistry J Tate J Boursnell C Pang N Forslund K Ceric G Clements J Hcger A Holm L Sonnhammer E L Eddy S R Bateman A Finn R D | 2012 | Nucleic Acids Research2012，40，： | 1 |
| 7 | Progranulin (PC-cell-derived growth factor/acrogranin) regulates invasion and cell survival显示文摘 | He Z Ismail A Kriazhev L Sadvakassova G Bateman A | 2002 | Cancer Res2002，62，： | 1 |
| 8 | Relationship among Fusarium spp estimated by comparing restriction fragment length polymorphisms in polymerase chain reaction-am- plified nuclear rDNA 显示文摘 | Bateman G L Kwasna H Ward E | 1996 | Can J Microbiol1996，42，： | 1 |
| 9 | The paraspinal sacrospinalis - splitting approach to the lumbar spine 显示文摘 | Wiltse L L Bateman J G Hutchinson R H | 1968 | J Bone Joint Surg Am1968，50，5： | 1 |
| 10 | Evaluation of ruminally protected methionine and lysine or blood meal and fish meal as protein sources for lactating Holsteins显示文摘 | Spain J N Kerley M S Belyea R L and Marshall R T | 1999 | J Dairy Sci1999，82，： | 1 |
| 11 | Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)显示文摘 | Bentley SD Chater KF Cerdeno-Tarraga AM Challis GL Thomson NR James KD Harris DE Quail MA Kieser H Harper D Bateman A Brown S Chandra G Chen CW Collins M Cronin A Fraser A Goble A Hidalgo J Hornsby T Howarth S Huang CH Kieser T Larke L Murphy L Oliver K O | | 0，，： | 1 |
| 12 | Pathogenicity of fungi associated with winter loss and injury in white lupin显示文摘 | Bateman G L | 1997 | Plant Pathology1997，46，2： | 1 |
| 13 | Recent advances in aryl-aryl bond formation by direct arylation显示文摘 | McGlacken G P Bateman L M | | 0，，08： | 1 |
| 14 | Effect of Weaning Age of Dairy Calves Fed a Conventional or More Optimum Milk Replacer Program显示文摘 | Hill T M Bateman H G Aldrich J M Schlotterbeck R L | 2009 | Professional Animal Scientist2009，，： | 1 |
| 15 | The paraspinal sacrospinalis-splitting approach to the lumbar spine显示文摘 | Wihse L L Bateman J G Hutchinson R H | 1968 | J Bone Joint SurgAm1968，50，5： | 1 |
| 16 | Comparison of Gaeumannomyces- and Phialophora -like fungal pathogens from maize and other plants using DNA methods显示文摘 | Ward E Bateman G L | 1999 | New Phytol1999，141，： | 1 |
| 17 | Recent advances in aryl-aryl bond formation by direct arylation显示文摘 | MCGLACKEN G P BATEMAN L M | | 0，，08： | 1 |
| 18 | The Pfam protein families database 显示文摘 | Finn RD Mistry J Tate J Coggill P Heger A Pollington JE Gavin OL Gunasekaran P Ceric G Forslund K Holm L Sonnhammer EL Eddy SR Bateman A | 2010 | Nucleic Acids Res2010，38，： | 1 |
| 19 | Detection of circulating tumor cells with the magnetic activated cell sorter显示文摘 | Wong L S Bateman W J Morris A G | 1995 | Br J Surg1995，82，13： | 1 |
| 20 | The paraspinal attcrospinalis-splitting approach to the lumbar spine显示文摘 | Wiltse L L Bateman J G Hutchinson R H | 1968 | J Bone Joint Surg(Am)1968，50，5： | 1 |
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