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    题名 作者 年代 出处 被引量
1恶性弥漫型腱鞘滑膜巨细胞肿瘤显示文摘Li C F Wang J W Huang W W 黄文斌(摘译) 2008临床与实验病理学杂志2008,24,4:12
2酒精摄入、心脏生物标志物和心房颤动风险与不良结局显示文摘酒精摄入和新发心房颤动相关性证据不一,尤其是在低剂量下。该研究评估欧洲队列在整个饮酒范围内酒精摄入、生物标志物和新发心房颤动的关系。方法和结果:在一个以社区为基础的汇集队列中,研究者随访107845人,以评估酒精摄入(酒精种类和饮酒方式)与新发心房颤动的关系。研究者收集经典心血管病危险因素和新发心力衰竭的信息,并检测生物标记物氨基末端脑钠肽前体和高敏肌钙蛋白I。陈嘉睿(译) 练桂丽((审校) Csengeri D Sprünker NA Di Castelnuovo A Niiranen T Vishram-Nielsen JK Costanzo S S derberg S Jensen SM Vartiainen E Donati MB Magnussen C Camen S Gianfagna F L chen ML Kee F Kontto J Mathiesen EB Koenig W Stefan B de Gaetano G J rgensen T Kuulasmaa K Zeller T Salomaa V Iacoviello L Schnabel RB 2021中华高血压杂志2021,29,2:9
3Gastroenteropancreatic neuroendocrine tumours显示文摘Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin 2008Lancet Oncology2008,,1:8
4High-density SNP-based genetic maps for the parents of an outcrossed and a selfed tetraploid garden rose cross, inferred from admixed progeny using the 68k rose SNP array显示文摘Dense genetic maps create a base for QTL analysis of important traits and future implementation of marker-assisted breeding.In tetraploid rose,the existing linkage maps include<300 markers to cover 28 linkage groups(4 homologous sets of 7 chromosomes).Here we used the 68k WagRhSNP Axiom single-nucleotide polymorphism(SNP)array for rose,in combination with SNP dosage calling at the tetraploid level,to genotype offspring from the garden rose cultivar‘Red New Dawn’.The offspring proved to be not from a single bi-parental cross.In rose breeding,crosses with unintended parents occur regularly.We developed a strategy to separate progeny into putative populations,even while one of the parents was unknown,using principle component analysis on pairwise genetic distances based on sets of selected SNP markers that were homozygous,and therefore uninformative for one parent.One of the inferred populations was consistent with self-fertilization of‘Red New Dawn’.Subsequently,linkage maps were generated for a bi-parental and a self-pollinated population with‘Red New Dawn’as the common maternal parent.The densest map,for the selfed parent,had 1929 SNP markers on 25 linkage groups,covering 1765.5 cM at an average marker distance of 0.9 cM.Synteny with the strawberry(Fragaria vesca)genome was extensive.Rose ICM1 corresponded to F.vesca pseudochromosome 7(Fv7),ICM4 to Fv4,ICM5 to Fv3,ICM6 to Fv2 and ICM7 to Fv5.Rose ICM2 corresponded to parts of F.vesca pseudochromosomes 1 and 6,whereas ICM3 is syntenic to the remainder of Fv6.Mirjana Vukosavljev Paul Arens Roeland E Voorrips Wendy P C van't Westende G D Esselink Peter M Bourke Peter Cox W Eric van de Weg Richard G F Visser Chris Maliepaard Marinus J M Smulders 2016Horticulture Research2016,3,1:6
5Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility:a case-control analysis显示文摘The BRCA1 Associated RING Domain(BARD1) gene has been identified as a high penetrance gene for breast cancer, whose germline and somatic mutations were reported in both non-BRCA1/2 hereditary site-specific and sporadic breast cancer cases. BARD1 plays a crucial role in tumor repression, along with its heterodimeric partner BRCA1. In the current study, we tested the hypothesis that common non-synonymous polymorphisms in BARD1 are associated with breast cancer susceptibility in a case-control study of 507 patients with incident breast cancer and 539 frequency-matched cancer-free controls in Chinese women. We genotyped all three common(minor allele frequency (MAF) > 0.10) non-synonymous polymorphisms(Pro24Ser, Arg378Ser, and Val507Met) in BARD1. We found that the BARD1 Pro24Ser variant genotypes(24Pro/Ser and 24Ser/Ser) and Arg378Ser variant homozygote 378Ser/Ser were associated with a significantly decreased breast cancer risk, compared with their wild-type homozygotes, respectively. Furthermore, a significant locus-locus interaction was evident between Pro24Ser and Arg378Ser (P-int = 0.032). Among the 378Ser variant allele carriers, the 24Pro/Pro wild-type homozygote was associated with a significantly increased breast cancer risk (adjusted OR = 1.81, 95% CI = 1.11-2.95), but the subjects having 24Pro/Ser or Ser/Ser variant genotypes had a significantly decreased risk(adjusted OR = 0.74, 95% CI = 0.56-0.99). In stratified analysis, this locus-locus interaction was more evident among subjects without family cancer history, those with positive estrogen receptor (ER) and individuals with negative progesterone receptor(PR). These findings indicate that the potentially functional polymorphisms Pro24Ser and Arg378Ser in BARD1 may jointly contribute to the susceptibility of breast cancer.Huo, X Hu, Z. B Zhai, X. J Wang, Y Wang, S Wang, X. C Qin, J. W Chen, W. S Jin, G. F Liu, J. Y Gao, J Wei, Q. Y Wang, X. R Shen, H. B 2007南京医科大学学报(自然科学版)2007,27,7:3
6In vitro and in vivo pharmacological characterization of BIIL 284, a novel and potent leukotriene B(4) receptor antagonist 显示文摘Birke F W Meade C J Anderskewitz R 2001J Pharmacol Exp Ther2001,297,:2
7Factors affecting phosphate adsorption equilibria in lake sediments显示文摘Ku W C Digiano F A Feng T H 1978Water Res1978,12,:2
8Brittle elastoplastic damage constitutive model for jointed rockmass and computation concerning bolt-reinforcement显示文摘Zhu W Zhang Q Li S Lee C F 2003International Journal of Damage Mechanics2003,12,:2
9Effect of interleaving on the impact response of a unidirectional carbon/epoxy composite显示文摘Lu W H Liao F S Su A C 1995Composites1995,26,3:2
10卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景 缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 2017国际脑血管病杂志2017,25,5:2
11Effects of teratogenic exposures to Zn2+, Cd2+, Ni2+, Co2+ and Cu2+ on metal- lothionein and metallothionein- mRNA contents of xenopus embryos显示文摘Sunderman F W Jr Plownam M C Kroftova O S 1995Pharmacol Toxicol1995,76,3:2
12Phylogenetic relationships of the Tropiduchidae-group(Homoptera:Fulgoroidea)of planthoppers inferred through nucleotide sequences显示文摘YEH W B YANG C T HUI C F 1998Zool Stu1998,37,1:2
13甜菜碱对肥育猪生长激素脉冲释放和血清代谢的影响显示文摘用添加含量为0和0.125%甜菜碱的日粮饲喂肥育猪,试验对杂交肥育猪日粮中甜菜碱对猪的生长性能、生长激素(GH)脉冲释放及血清代谢的影响进行研究。每试验组3个重复,每个重复8头猪(4头去势公猪,4头母猪),试验在饲喂后3h内每15min采集一次血液样本,测定生长激素脉冲释放。结果表明:添加甜菜碱组平均日增重增加5.45%(P〈0.05),而平均日采食量和饲料转化率则不受影响。Huang Q C Xu Z R Han X Y Li W F 2007饲料博览(技术版)2007,,7:2
14Which Time-to-Peak Threshold Best Identifies Penumbral Flow?: A Comparison of Perfusion-Weighted Magnetic Resonance Imaging and Positron Emission Tomography in Acute Ischemic Stroke显示文摘J Sobesky O Zaro Weber F -G. Lehnhardt V Hesselmann A Thiel C Dohmen A Jacobs M Neveling W -D. Heiss 2004Stroke2004,,12:2
15Interoperability of Design Intent in Integrated Product and Process Design显示文摘Concurrent engineering is currently an overwhelming t rend in product development since it takes the down-stream product development issues and product life-cycle issues into consideration in up-front design pro cess. At this stage, evaluation, verification and validation of design concepts and design schemes is critical to the right-to-market product development. I dentification and extraction of design intent from the part digital mock-ups in different data formats and created in different CAD systems for DFX considerati on, evaluation, verification, and validation is crucial too. Traditionally, fro m manufacturing point of view, feature identification and extraction is to get t he features and feature-related information for manufacturing planning and inte gration. Presently, from the viewpoint of product development and product servi ce life cycle, design intent identification and extraction is to get all the des ign-related information for DFX consideration in early design stage, such as de sign for assembly, design for service, design for tooling, design for functional ity and design for environment etc. Therefore, how to successfully extract desi gn intent such as design and machining features and design-related information from the prototyping digital mock-ups created by different CAD systems for DFX consideration in upstream design stage is a very useful topic in integrated prod uct and process design and development. Presently, there are heterogeneous CAD systems in the market and the interoperat ion among the different CAD systems is indispensable. The interoperability of d ifferent CAD systems is by way of data exchanged technology such as STEP and IGE S. The critical weakness of this interoperation technology is that much of the design intent is lost in the interoperation process. Once the product digital m ock-ups is exchanged via data exchange technology such as IGES or STEP, the des ign intent including the dimension-driven design features and other attributes embedded in the part model are lost in the data translation process. Models rea d out of CAD systems come into other systems as featureless chunks of geometry e ntities. Obviously, the interoperation technology does not satisfy the industry need. It has been reported that this poor interoperation technology, which pro vides poor CAD models in neutral-format geometry had cost the automobile indust ry alone $1 billon per year. Fortunately, some researchers have been aware of t he criticality of this since only the United States industry spends billons of d ollars as a result of poor interoperability between computer-aided engineering software tools. In the past, product development was often done within a single company by co-located design team. In more recent years, there has been a busi ness paradigm shift in product development as the product development is being d one more often by geographically and temporally distributed design teams. There is a high level of outsourcing, not only of manufacturing but also of actual pr oduct development effort. Besides, product development across companies, and ev en within a single company, is often done within a heterogeneous software tool e nvironment. How to improve the interoperability of design intent created in het erogeneous software tool environment geographically has become a critical issue in next-generation product development system. Design intent in this research is defined as the outcome of design process. Des ign process goes from the identification of needs to satisfaction of that needs. Design intent satisfies this kind of needs. In this research, design intent i s created in a CAD system and embedded in part CAD model. The detailed design i ntent here includes design and manufacturing features and the feature-relat ed information such as feature parameters, feature relationships and some relate d characteristics such as associativity. Interoperability refers to the ability to share and communicate in the heterogeneous environment or heterogeneous softM W Fu W F Lu A Y C Nee S K Ong 2002厦门大学学报(自然科学版)2002,41,S1:2
16Screening of subclinical hepatic encephalopathy显示文摘Michael Groeneweg Wendy Moerland Juan C Quero Wim C.J Hop Paul F Krabbe Solko W Schalm 2000Journal of Hepatology2000,,5:2
17Kontrastmittelsonografie bei B-Bild-morphologisch unklaren Leberraumforderungen – Diagnostische Treffsicherheit im klinischen Alltag (DEGUM-Multicenter – Studie)显示文摘D Strobel K Seitz W Blank A Schuler C Dietrich A Herbay M Friedrich-Rust G Kunze D Becker U Will W Kratzer F Albert C Pachmann K Dirks H Strunk C Greis T Bernatik 2008Ultraschall in Med2008,,05:2
18A method for rapid determination of lactose显示文摘Teles F F Young C K Stull J W 1978J Dairy Sci1978,61,:2
19Engrafted bone marrow-derived flk-(1+) mesenchymal stem cells regenerate skin tissue显示文摘Deng W Han Q Liao L Li C Ge W Zhao Z You S Deng H Murad F Zhao RC 2006中国生物学文摘2006,20,5:2
20A DNA vector-based RNAi technology to suppress gene expression in mammalian cells显示文摘Sui G Soohoo C Affar el B Gay F Shi Y Forrester W C Shi Y 0,,:2
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