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| 1 | Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial显示文摘 | Somnath Mukherjee Christopher N Hurt John Bridgewater Stephen Falk Sebastian Cummins Harpreet Wasan Tom Crosby Catherine Jephcott Rajarshi Roy Ganesh Radhakrishna Alec McDonald Ruby Ray George Joseph John Staffurth Ross A Abrams Gareth Griffiths Tim Maugh | 2013 | Lancet Oncology2013，，4： | 4 |
| 2 | Prevalence and virological profiles of hepatitis B infection in human immunodeficiency virus patients显示文摘AIM: To determine the prevalence of hepatitis B virus (HBV) in adult human immunodeficiency virus (HIV) patients with CD4+ T-cell count less than 500/mm 3 and without antiretroviral therapy; to describe different HBV-HIV coinfection virological profiles; and to search for factors associated with HBs antigen (HBsAg) presence in these HIV positive patients.METHODS: During four months (June through September 2006), 491 patients were received in four HIV positive monitoring clinical centers in Abidjan. Inclusion criteria: HIV-1 or HIV-1 and 2 positive patients, age ≥ 18 years, CD4+ T-cell count < 500/mL and formal and signed consent of the patient. Realized blood tests included HIV serology, CD4+ T-cell count, quantitative HIV RNA load and HBV serological markers, such as HBsAg and HBc antibody (anti-HBcAb). We performed HBeAg, anti-HBe antibody (anti-HBeAb), anti-HBc IgM and quantitative HBV DNA load in HBsAg positive patients. Anti-HBsAb had been tested in HIV patients with HBsAg negative and anti-HBcAb-positive. HBV DNA was also tested in 188 anti-HBcAb positive patients with HBsAg negative status and without anti-HBsAb. Univariate analysis (Pearsonχ 2 test or Fischer exact test) and multivariate analysis (backward step-wise selection logistic regression) were performed as statistical analysis. RESULTS: Mean age of 491 patients was 36 ± 8.68 years and 73.3% were female. Type-1 HIV was found in 97% and dual-type HIV (type 1 plus type 2) in 3%. World Health Organization (WHO) clinical stage was 1, 2, 3 and 4 respectively in 61 (12.4%), 233 (47.5%), 172 (35%) and 25 patients (5.1%). Median CD4+ T-cell count was 341/mm 3 (interquartile range: 221-470). One hundred and twelve patients had less than 200 CD4+ T-cell/mm 3 . Plasma HIV-1 RNA load was elevated (≥ 5 log 10 copies/mL) in 221 patients (45%). HBsAg and anti-HBcAb prevalence was respectively 13.4% and 72.9%. Of the 66 HBsAg positive patients, 22 were inactive HBV carriers (33.3%), 21 had HBeAg positive hepatitis (31.8%) and 20 had HBeAg negative hepatitis (30.3%). HBeAg and anti-HBeAb were indeterminate in 3 of them. Occult B infection prevalence (HBsAg negative, anti-HBcAb positive, anti-HBsAb negative and detectable HBV DNA) was 21.3%. Three parameters were significantly associated with the presence of HBsAg: male [odds ratio (OR): 2.2;P = 0.005; 95% confidence interval (CI): 1.3-3.8]; WHO stage 4 (OR: 3.2;P = 0.01;95% CI: 1.3-7.9); and aspartate aminotransferase (AST) level higher than the standard (OR: 1.9;P = 0.04; 95% CI: 1.02-3.8). CONCLUSION: HBV infection prevalence is high in HIV-positive patients. HBeAg positive chronic hepatitis and occult HBV infection are more frequent in HIVpositive patients than in HIV negative ones. Parameters associated with HBsAg positivity were male gender, AIDS status and increased AST level. | Koffi Alain Attia Serge Eholié Eugène Messou Christine Danel Sandrine Polneau Henri Chenal Thomas Toni Myreille Mbamy Catherine Seyler Naomi Wakasugi Thérèse N'dri-Yoman Xavier Anglaret | 2012 | World Journal of Hepatology2012，4，7： | 4 |
| 3 | Heavy metal removal from sediments by biosurfactants显示文摘 | Catherine N Mulligan Raymond N Yong Bernard F Gibbs | 2001 | Journal of Hazardous Materials2001，，1： | 2 |
| 4 | Evaluation of ethnobotanically selected Benin medicinal plants for their in vitro antiplasmodial activity显示文摘 | Bernard Weniger Latifou Lagnika Catherine Vonthron-Sénécheau Tomabu Adjobimey Joachim Gbenou Mansourou Moudachirou Reto Brun Robert Anton Ambaliou Sanni | 2003 | Journal of Ethnopharmacology2003，，2： | 2 |
| 5 | Antibiosis revisited: bacterio- cins produced by dairy starter cultures显示文摘 | Susan F B Catherine G N | 1993 | Journal of Dairy Science1993，76，8： | 1 |
| 6 | Microbes Central to Human Reproduction显示文摘 | Gregor Reid Patrizia Brigidi Jeremy P. Burton Nikhat Contractor Sylvia Duncan Emilie Fargier Colin Hill Sarah Lebeer Rocio Martín Andrew J. McBain Gil Mor Catherine O’Neill Juan Miguel Rodríguez Jonathan Swann Saskia Hemert Juliett Ansell | 2015 | Am J Reprod Immunol2015，，1： | 1 |
| 7 | Automation and optimization of glycine Synthesis显示文摘 | Mehrdad N Catherine P | 1996 | Process Control Qual1996，8，1： | 1 |
| 8 | Ccurrence of arsenic contamination in Canada: Sources, behavior and distribution 显示文摘 | Suiling Wang Catherine N Mulligan O | 2006 | Science of the Total Environment2006，366，： | 1 |
| 9 | Identification of the DNA Binding specificity and potential target genes for the farnesold X-activated receptor显示文摘 | Bryan A L Heidi R K Catherine M N | 2000 | J Biol Chem2000，275，10： | 1 |
| 10 | Inverse association between the effect of carbohydrates on blood glucose and subsequent short term food intake in young men 显示文摘 | Anderson G H Catherine N L Woodend D M | 2002 | American Journal of Clinical Nutrition2002，76，5： | 1 |
| 11 | Risk factors for liver disease among adults of Mexican descent in the United States and Mexico显示文摘AIM To compare the prevalence of chronic liver disease(CLD) risk factors in a representative sample of MexicanAmericans born in the United States(US) or Mexico, to a sample of adults in Mexico.METHODS Data for Mexican-Americans in the US were obtained from the 1999-2014 National Health and Nutrition Examination Survey(NHANES), which includes persons of Mexican origin living in the US(n = 4274). The NHANES sample was restricted to Mexican-American participants who were 20 years and older, born in the US or Mexico, not pregnant or breastfeeding, and with medical insurance.The data in Mexico were obtained from the 2004-2013 Health Worker Cohort Study in Cuernavaca, Mexico(n =9485). The following known risk factors for liver disease/cancer were evaluated: elevated aminotransferase levels(elevated alanine aminotransferase was defined as > 40 IU/L for males and females; elevated aspartate aminotransferase was defined as > 40 IU/L for males and females), infection with hepatitis B or hepatitis C,metabolic syndrome, high total cholesterol, diabetes,obesity, abdominal obesity, and heavy alcohol use. The main independent variables for this study classified individuals by country of residence(i.e., Mexico vs the US) and place of birth(i.e., US-born vs Mexico-born).Regression analyses were used to investigate CLD risk factors.RESULTS After adjusting for socio-demographic characteristics,Mexican-American males were more likely to be obese,diabetic, heavy/binge drinkers or have abdominal obesity than males in Mexico. The adjusted multivariate results for females also indicate that Mexican-American females were significantly more likely to be obese, diabetic, be heavy/binge drinkers or have abdominal obesity than Mexican females. The prevalence ratios and prevalence differences mirror the multivariate analysis findings for the aforementioned risk factors, showing a greater risk among US-born as compared to Mexico-born MexicanAmericans. CONCLUSION In this study, Mexican-Americans in the US had more risk factors for CLD than their counterparts in Mexico.These findings can be used to design and implement more effective health promotion policies and programs to address the specific factors that put Mexicans at higher risk of developing CLD in both countries. | Yvonne N Flores Zuo-Feng Zhang Roshan Bastani Mei Leng Catherine M Crespi Paula Ramírez-Palacios Heather Stevens Jorge Salmerón | 2018 | World Journal of Gastroenterology2018，24，37： | 1 |
| 12 | 显示文摘 | Sabine T Friede N Catherine L | 1999 | Oncogene1999，18，47： | 1 |
| 13 | A DSC study on cure kinetics of HTPB-IPDI urethane reaction显示文摘 | CATHERINE K B KRISHNAN K NINAN K N | 2000 | Journal of Thermal Analysis and Calorimetry2000，59，12： | 1 |
| 14 | Oral combination therapy with a nucleoside polymerase inhibitor (RG7128) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): a randomised, double-blind, placebo-controlled, dose-escalation trial显示文摘 | Edward J Gane Stuart K Roberts Catherine AM Stedman Peter W Angus Brett Ritchie Rob Elston David Ipe Peter N Morcos Linda Baher Isabel Najera Tom Chu Uri Lopatin M Michelle Berrey William Bradford Mark Laughlin Nancy S Shulman Patrick F Smith | 2010 | The Lancet2010，，9751： | 1 |
| 15 | Inverse associa- tion between the effect of carbohydrates on blood glucose and subsequent short term food intake in young men显示文摘 | Anderson G H Catherine N L Woodend D M | 2002 | American Journal of Clinical Nutrition2002，76，5： | 1 |
| 16 | Rheology and microstructure of k-carrageenan under different conformations induced by several concentrations of potassium ion显示文摘 | M C Nú(n)ez-Santiago Alberto Tecante Catherine Garnier | | 0，，01： | 1 |
| 17 | Diet quality of montrealarea adults needs improvement: estimates from a self-administerod food frequency questionnaire furnishing a dietary indicator score 显示文摘 | BRYNA S SYLVIE N CATHERINE G | 2005 | J Am Diet Assoc2005，105，： | 1 |
| 18 | Accessibility as a determinant of landscape transformation in western Honduras:linking pattern and process显示文摘 | Jane S Catherine T | 2003 | Landscape Ecology2003，18，： | 1 |
| 19 | Cranberry and blueberry:Evidence for protective ef- fects against cancer and vascular diseases显示文摘 | Catherine C N | 2007 | Mol Nutr Food Res2007，51，6： | 1 |
| 20 | Anticoagulant low molecular weight fucans produced by radical process and ion exchange chromatography of high molecular weight fucans extracted from the brown seaweed Ascophyllum modosum显示文摘 | Alain N Frederic C Catherine B V | 1991 | Carbohydrate Research1991，289，： | 1 |
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