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| 1 | Indole alkaloid sulfonic acids from an aqueous extract of Isatis indigotica roots and their antiviral activity显示文摘Six new indole alkaloid sulfonic acids(1–6), together with two analogues(7 and 8) that were previously reported as synthetic products, were isolated from an aqueous extract of the Isatis indigotica root. Their structures including the absolute configurations were determined by spectroscopic data analysis, combined with enzyme hydrolysis and comparison of experimental circular dichroism and calculated electronic circular dichroism spectra. In the preliminary assay, compounds 2 and 4 showed antiviral activity against Coxsackie virus B3 and influenza virus A/Hanfang/359/95(H3N2), respectively. | Lingjie Meng Qinglan Guo Yufeng Liu Minghua Chen Yuhuan Li Jiandong Jiang Jiangong Shi | 2017 | Acta Pharmaceutica Sinica B2017，7，3： | 14 |
| 2 | Spiral Steel Wire Based Fiber-Shaped Stretchable and Tailorable Triboelectric Nanogenerator for Wearable Power Source and Active Gesture Sensor显示文摘Continuous deforming always leads to the performance degradation of a flexible triboelectric nanogenerator due to the Young’s modulus mismatch of different functional layers.In this work,we fabricated a fiber-shaped stretchable and tailorable triboelectric nanogenerator(FST-TENG)based on the geometric construction of a steel wire as electrode and ingenious selection of silicone rubber as triboelectric layer.Owing to the great robustness and continuous conductivity,the FST-TENGs demonstrate high stability,stretchability,and even tailorability.For a single device with ~6 cm in length and ~3 mm in diameter,the open-circuit voltage of ~59.7 V,transferred charge of ~23.7 nC,short-circuit current of ~2.67 μA and average power of ~2.13 μW can be obtained at 2.5 Hz.By knitting several FST-TENGs to be a fabric or a bracelet,it enables to harvest human motion energy and then to drive a wearable electronic device.Finally,it can also be woven on dorsum of glove to monitor the movements of gesture,which can recognize every single finger,different bending angle,and numbers of bent finger by analyzing voltage signals. | Lingjie Xie Xiaoping Chen Zhen Wen Yanqin Yang Jihong Shi Chen Chen Mingfa Peng Yina Liu Xuhui Sun | 2019 | Nano-Micro Letters2019，11，3： | 13 |
| 3 | Triboelectric–Electromagnetic Hybrid Generator for Harvesting Blue Energy显示文摘Progress has been developed in harvesting lowfrequency and irregular blue energy using a triboelectric–electromagnetic hybrid generator in recent years. However,the design of the high-efficiency, mechanically durable hybrid structure is still challenging. In this study, we report a fully packaged triboelectric–electromagnetic hybrid generator(TEHG), in which magnets were utilized as the trigger to drive contact–separation-mode triboelectric nanogenerators(CS-TENGs) and coupled with copper coils to operate rotary freestanding-mode electromagnetic generators(RF-EMGs). The magnet pairs that produce attraction were used to transfer the external mechanical energy to the CS-TENGs, and packaging of the CS-TENGpart was achieved to protect it from the ambient environment. Under a rotatory speed of 100 rpm, the CS-TENGs enabled the TEHG to deliver an output voltage, current,and average power of 315.8 V, 44.6 μA, and ~ 90.7 μW,and the output of the RF-EMGs was 0.59 V, 1.78 m A, and 79.6 μW, respectively. The cylinder-like structure made the TEHG more easily driven by water flow and demonstrated to work as a practical power source to charge commercial capacitors. It can charge a 33μF capacitor from 0 to 2.1 V in 84 s, and the stored energy in the capacitor can drive an electronic thermometer and form a self-powered water-temperature sensing system. | Huiyun Shao Ping Cheng Ruixuan Chen Lingjie Xie Na Sun Qingqing Shen Xiaoping Chen Qianqian Zhu Yi Zhang Yina Liu Zhen Wen Xuhui Sun | 2018 | Nano-Micro Letters2018，10，3： | 9 |
| 4 | Isatindolignanoside A, a glucosidic indole-lignan conjugate from an aqueous extract of the Isatis indigotica roots显示文摘A glucosidic indole-lignan conjugate with a novel carbon skeleton, named isatindolignanoside A(1), was isolated from an aqueous extract of the Isatis indigotica roots 'ban lan gen'. Its structure was elucidated by comprehensive analysis of spectroscopic data, including J-and NOESY correlation-based configurational analysis, circular dichroism(CD) data, enzyme hydrolysis, and theoretical ECD calculation. In a preliminary assay, compound 1 showed antiviral activity against Coxsackie virus B3. This compound is the first example of natural product having a structural feature of conjugation between indole and lignan units, and its biosynthetic pathway is postulated. | Lingjie Meng Qinglan Guo Minghua Chen JiANDong Jiang Yuhuan Li Jiangong Shi | 2018 | Chinese Chemical Letters2018，29，8： | 7 |
| 5 | The Chinese Hα Solar Explorer(CHASE) mission: An overview显示文摘The Chinese Hα Solar Explorer(CHASE), dubbed “Xihe”—Goddess of the Sun, was launched on October 14, 2021 as the first solar space mission of China National Space Administration(CNSA). The CHASE mission is designed to test a newly developed satellite platform and to acquire the spectroscopic observations in the Hα waveband. The Hα Imaging Spectrograph(HIS)is the scientific payload of the CHASE satellite. It consists of two observational modes: raster scanning mode and continuum imaging mode. The raster scanning mode obtains full-Sun or region-of-interest spectral images from 6559.7 to 6565.9 ? and from 6567.8 to 6570.6 ? with 0.024 ? pixel spectral resolution and 1 min temporal resolution. The continuum imaging mode obtains photospheric images in continuum around 6689 ? with the full width at half maximum of 13.4 ?. The CHASE mission will advance our understanding of the dynamics of solar activity in the photosphere and chromosphere. In this paper, we present an overview of the CHASE mission including the scientific objectives, HIS instrument overview, data calibration flow, and first results of on-orbit observations. | Chuan Li Cheng Fang Zhen Li MingDe Ding PengFei Chen Ye Qiu Wei You Yuan Yuan MinJie An HongJiang Tao XianSheng Li Zhe Chen Qiang Liu Gui Mei Liang Yang Wei Zhang WeiQiang Cheng JianXin Chen ChangYa Chen Qiang Gu QingLong Huang MingXing Liu ChengShan Han HongWei Xin ChangZheng Chen YiWei Ni WenBo Wang ShiHao Rao HaiTang Li Xi Lu Wei Wang Jun Lin YiXian Jiang LingJie Meng Jian Zhao | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，8： | 7 |
| 6 | Pickering emulsions stabilized by colloidal surfactants:Role of solid particles显示文摘Pickering emulsions are emulsions stabilized by colloidal surfactants,i.e.solid particles.Compared with traditional molecular suffactant-stabilized emulsions,Pickering emulsions show many advantages,such as high resistance to coalescence,long-term stability,good biocompatibility and tunable properties.In recent years,Pickering emulsions are widely applied in scientific researches and industrial applications.In this review,we focus on the influences of particle properties on Pickering emulsions,including particle amphiphilicity,concentration,size and shape,and summarize the strategies developed for the preparation of amphiphilic Janus particles.The applications of Pickering emulsions in food industry,cosmetic industry,material science,drug delivery,biomedical research and vaccine adjuvant will also be covered.Pickering emulsions are a unique system for multi-disciplinary studies and will become more and more important in the future. | Zhu Sun Xiaoxiao Yan Yao Xiao Lingjie Hu Max Eggersdorfer Dong Chen Zhenzhong Yang David AWeitz | 2022 | Particuology2022，20，5： | 6 |
| 7 | Nonlinear Adaptive Control Using Neural Networks and Multiple Models显示文摘 | Chen Lingji Narendra K S | | 0，，08： | 1 |
| 8 | Nonlinear adaptive control using neural networks and multiple models 显示文摘 | CHEN Lingji NARENDRA K S | 2001 | Automatica2001，37，8： | 1 |
| 9 | Nonlinear adaptive control using neural networks and multiple models显示文摘 | Chen Lingji Narendra K S | 2001 | Automatica2001，37，8： | 1 |
| 10 | Identification and control of a nonlinear discrete-time system based on its linearization: A unified framework显示文摘 | Chen Lingji Narendra K S | 2004 | IEEE Trans on Neural Networks2004，15，3： | 1 |
| 11 | Polymorphisms of β-adrenoceptor and Natriuretic Peptide Receptor Genes Influence the Susceptibility to and the Severity of Idiopathic Dilated Cardiomyopathy in a Chinese Cohort显示文摘 | Lingjie Wang Lin Lu Fengru Zhang Qiujing Chen Weifeng Shen | 2010 | Journal of Cardiac Failure2010，，1： | 1 |
| 12 | Visualized and cascade-enhanced gene silencing by smart DNAzyme-graphene nanocomplex显示文摘BCL-2 gene as well as its products is recognized as a promising target for the molecular targeted therapy of tumors.However,due to certain defense measures of tumor cells,the therapeutic effect based on the gene silencing of BCL-2 is greatly reduced.Here we fabricate a smart response nucleic acid therapeutic that could silence the gene effectively through a dual-targeted and cascade-enhanced strategy.In brief,nano-graphene oxide(GO),working as a nano-carrier,is loaded with a well-designed DNAzyme,which can target and silence the BCL-2 mRNA.Furthermore,upon binding with the BCL-2 mRNA,the enzymatic activity of the DNAzyme can be initiated,cutting a substrate oligonucleotide to produce an anti-nucleolin aptamer AS1411.Nucleolin,a nucleolar phosphoprotein,is known as a stabilizer of BCL-2 mRNA.Via binding and inactivating the nucleolin,AS1411 can destabilize BCL-2 mRNA.By this means of simultaneously targeting mRNA and its stabilizer in an integrated system,effective silencing of the BCL-2 gene of tumor cells is achieved at both the cellular and in vivo levels.After being dosed with this nucleic acid therapeutic and without any chemotherapeutics,apoptosis of tumor cells at the cellular level and apparent shrinkage of tumors in vivo are observed.By labeling a molecular beacon on the substrate of DNAzyme,visualization of the enzymatic activity as well as the tumor in vivo can be also achieved.Our work presents a pure bio-therapeutic strategy that has positive implications for enhancing tumor treatment and avoiding side effects of chemotherapeutics. | Lingjie Ren Xiaoxia Chen Chang Feng Lei Ding Xiaomin Liu Tianshu Chen Fan Zhang Yanli Li Zhongliang Ma Bo Tian Xiaoli Zhu | 2020 | Nano Research2020，13，8： | 1 |
| 13 | Inhibition Effect of Propargyl Alcohol on the Stress Corrosion Cracking of Super 13Cr Steel in a Completion Fluid显示文摘 | CHEN Zhenyu LI Lingjie ZHANG Guo'an | 2013 | Corrosion Science2013，69，： | 1 |
| 14 | Two-Level Hierarchical PCG Methods for the Quadratic FEM Discretizations of 2D Concrete Aggregate Models显示文摘The concrete aggregate model is considered as a type of weakly discontinuous problem consisting of three phases:aggregates which randomly distributed in different shapes,cement paste and internal transition zone(ITZ).Because of different shapes of aggregate and thin ITZs,a huge number of elements are often used in the finite element(FEM)analysis.In order to ensure the accuracy of the numerical solutions near the interfaces,we need to use higher-order elements.The widely used FEM softwares such as ANSYS and ABAQUS all provide the option of quadratic elements.However,they have much higher computational complexity than the linear elements.The corresponding coefficient matrix of the system of equations is a highly ill-conditioned matrix due to the large difference between three phase materials,and the convergence rate of the commonly used solving methods will deteriorate.In this paper,two types of simple and efficient preconditioners are proposed for the system of equations of the concrete aggregate models on unstructured triangle meshes by using the resulting hierarchical structure and the properties of the diagonal block matrices.The main computational cost of these preconditioners is how to efficiently solve the system of equations by using linear elements,and thus we can provide some efficient and robust solvers by calling the existing geometric-based algebraic multigrid(GAMG)methods.Since the hierarchical basis functions are used,we need not present those algebraic criterions to judge the relationships between the unknown variables and the geometric node types,and the grid transfer operators are also trivial.This makes it easy to find the linear element matrix derived directly from the fine level matrix,and thus the overall efficiency is greatly improved.The numerical results have verified the efficiency of the resulting preconditioned conjugate gradient(PCG)methods which are applied to the solution of several typical aggregate models. | Yingxiong Xiao Heng Chen Lingjie Xie | 2019 | Advances in Applied Mathematics and Mechanics2019，11，6： | 1 |
| 15 | Nonlinear adaptive control using neural network and multiple model显示文摘 | Lingji Chen Narendra K S | 2001 | Automatica2001，37，3： | 1 |
| 16 | Nonlinear adaptive control using neural network and multiple models显示文摘 | Lingji Chen SNarendraK | 2001 | Automatica2001，37，： | 1 |
| 17 | Nonlinear adaptive control using neural networks and multiple models 显示文摘 | Chen Lingji Kumpati S Narendra | 2001 | Automatic2001，，37： | 1 |
| 18 | Nonlinear adaptive control using neural network and multiple models 显示文摘 | Lingji Chen K S Narendra | 2001 | Automatica (S0005-1098)2001，37，8： | 1 |
| 19 | Adaptive control design for nonaffine models arising in flight control 显示文摘 | Chen Lingji Mehra R K | 2004 | Journal of Guidance Control and Dynamics2004，27，2： | 1 |
| 20 | Nonlinear adaptive control using neural network and multiple models 显示文摘 | Lingji Chen S Narendra K | 2001 | Automatica2001，37，： | 1 |
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