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| 1 | Functional Heterogeneity of Cancer-Associated Fibroblasts from Human Colon Tumors Shows Specific Prognostic Gene Expression Signature显示文摘 | Mercedes Herrera Abul B.M.M.K. Islam Alberto Herrera Paloma Martín Vanesa García Javier Silva Jose M. Garcia Clara Salas Ignacio Casal Antonio García de Herreros Félix Bonilla Cristina Pe?a | 2013 | Clinical Cancer Research2013，，21： | 2 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification显示文摘MLL-AF4 熔化基因是在在婴儿的高风险的尖锐成淋巴细胞的白血病的一个特点 genomic 错误。尽管 MLL-AF4 在人的开发期间出生前地产生,这很好被建立,它在在 utero 的造血的开发的效果仍然保持未经勘探。我们创造了一个人特定的细胞的系统在 MLL-AF4-expressing 人的胚胎的干细胞(hESCs ) 学习早 hemato-endothelial 开发。介绍的功能的研究,同种细胞的分析和基因表示表明在 hESCs 的 MLL-AF4 的那表情有 phenotypic,功能并且基因表示影响。MLL-AF4 在 hESCs 充当全球 transcriptional 使活跃之物和 homeobox 基因表示的一个积极管理者。机能上地, MLL-AF4 从 hESCs 提高 hemogenic 先锋的说明,但是强烈损害进一步造血的承诺赞成 endothelial 房间命运。MLL-AF4 hESCs transcriptionally 被告知向对 endothelial 成熟敏感的 hemogenic 先锋区分,由联系到 vascular-endothelial 功能和早造血作用的主人基因的显著 upregulation 思考了。而且,我们报导那 MLL-AF4 表情不是足够的转变导出 hESC 的造血的房间。这个工作说明 hESCs 怎么可以提供唯一的卓见进人的开发并且推进我们理解白血病的熔化基因,知道出生前地产生,调整人的胚胎的造血的说明。 | Clara Bueno Rosa Montes Gustavo J Melen Verdnica Ramos-Mejia Pedro J Real Ver6nica Ayllo'n Laura Sanchez Gertmdis Ligero Inmaculada Gutierrez-Aranda Agustin F Femfindez Mario F Fraga Inmaculada Moreno-Gimeno Deborah Btlrks Maria del Carmen Plaza-Calonge Juan C Rodriguez-Manzaneque Pablo Menendez | 2012 | Cell Research2012，22，6： | 2 |
| 4 | Conformational comparion in the snake toxin family显示文摘 | Roberto J F Clara P Mirtha J | 1996 | Int J Peptide Protein Res1996，47，： | 1 |
| 5 | Spatially-resolved EELS analysis of antibody distribution on biofunctionalized magnetic nanoparticles显示文摘 | Raul A Laura D M Laura C Alvaro M Marcel T Valeria G Jesus M D L F Clara M Ricardo 1 | 2013 | ACS Nano2013，7，5： | 1 |
| 6 | Resolvin DI reduces the immunoinflammatory response of the rat eye following uveitis显示文摘 | Settimio R Clara DF Franca F | 2012 | Mediatom Inflamm2012，2012，31： | 1 |
| 7 | Rare-earth-doped transparent glass ceramics 显示文摘 | Goncalves M Clara Luis F Santos Rui M Almeida | 2002 | Comptes Rendus Chimie2002，5，12： | 1 |
| 8 | Pancreatic abscess caused by Candida following wide-spectrum antibiotic treatment 显示文摘 | De Vera F Martinez JF Clara Verdu R | 1998 | Gastroenterol Hepatol1998，21，4： | 1 |
| 9 | Does the Clam Ensis siliqua Provide Useful Information About Contamination by Polychlorinated Biphenyls and Organochlo~_ne Pesticides Beyond that of Mussel Mytilus galloprovincialis显示文摘 | Maria C F Maria T Ci Clara N | 2014 | Bulletin of Environmental Contamination and Toxicology2014，，92： | 1 |
| 10 | A new black fly isolate of Bacillus thuringiensis autoagglutinating strain highly toxic to Simulium pertinax 显示文摘 | Clara F G Rodrigo N F | 2005 | Mem Inst OswaldoCruz2005，100，7： | 1 |
| 11 | Design and development of miniature direct methanol fuel cell power sources for cellular phone applications显示文摘 | NARAYANAN S R VALDEZ T I Clara F | 2000 | Fuel Cell Seminar Abstracts Portland Oregon2000，，： | 1 |
| 12 | Use of lateral circumflex femoral artery system free flaps in skull base reconstruction 显示文摘 | Daniel C Angel F Clara M | 2011 | J Craniofac Surg2011，22，3： | 1 |
| 13 | Headspace solid -phase micro -extraction and gas chromatography-ion trap tandem mass spectrometry method for butyhin analysis in sediments: Optimization and validation显示文摘 | Pedro N Carvalho Luiz F Pinto M Clara P Basto | 2007 | Microchemical journal2007，87，2： | 1 |
| 14 | Prophylaxis of recurrent preeclampsia: low-molecular-weight heparin plus low-dose aspirin versus low-dose aspirin alone 显示文摘 | SERGIO F MARIA CLARA D GABRIELLA F | 2006 | Hypertens Pregnancy2006，25，2： | 1 |
| 15 | Rapid detection and serotyping of prunus necrotic ringspot virus in perennial crops by enzymelinked immmosorbent assay显示文摘 | Barbars D J ClarA M F Threch J M | 1978 | Ann Appl Biol1978，90，： | 1 |
| 16 | Relation Between The 6-Minute Walk Test And The Maximum Oxygen Consumption 显示文摘 | Walter V Clara L Luis F | 2007 | Chest Meeting Abstracts2007，，132： | 1 |
| 17 | Phytic acid level in edible grain derivatives in the canary islands(gofio and frangollo)显示文摘 | Clara I F Angeles A | 2000 | Europe Food Research Technology2000，210，： | 1 |
| 18 | Solvent regulation of oxygen affinity in hemoglobin 显示文摘 | CLARA F EMRZCO B CHAKLES O | 1984 | The Journal of Biological Chemistry1984，259，10： | 1 |
| 19 | Cerqueira functional characterisation and antimicrobial efficiency assessment of smart nanohydrogels containing natamycin incorporated into polysaccharide-based films 显示文摘 | CLARA F MARTIN M MIGUEL A | 2015 | Food and bioprocess technology2015，8，7： | 1 |
| 20 | Modules which are self-injective relative to closed submodules显示文摘 | SANTA Clara C SMITH P F | 1999 | Algebra and its applications1999，，： | 1 |
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