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| 1 | Direct interaction between CD155 and CD96 promotes immunosuppression in lung adenocarcinoma显示文摘Despite the advance in targeted therapy,lung adenocarcinoma(LUAD)remains one of the leading causes of death in patients with cancer.CD155,a member of poliovirus receptor–related(PRR)family,has been identified as the ligand of the Ig-like receptors tactile(CD96)and DNAM-1(CD226)on T cells.The interaction of CD155 with CD96 transmits an inhibitory signal and suppresses immune response.The interaction of CD155 with CD226 enhances the immune response.1,2,3 CD155 expression has been shown to be elevated in many types of cancers4,5 and is involved with immune suppression in melanoma.6 However,how CD155/CD96 is involved in immune response in the tumor microenvironment of LUAD remains unknown. | Hui Zhang Qianwen Liu Yiyan Lei Jianwen Zhou Wenting Jiang Yongmei Cui Qiong He Junfeng Zhu Zheng Zhu Yu Sun Zunfu Ke | 2021 | Cellular & Molecular Immunology2021，18，6： | 3 |
| 2 | Arabidopsis immune-associated nucleotide-binding genes repress heat tolerance at the reproductive stage by inhibiting the unfolded protein response and promoting cell death显示文摘Plants are vulnerable to heat stress,especially during reproductive development.The heat shock response(HSR)in the cytosol and nucleus,as well as the unfolded protein response(UPR)in the endoplasmic reticulum(ER),are two mechanisms that enable plants to survive heat stress.Excessive heat or ER stresses lead to cell death when the UPR cannot repair stress damage,but the means by which cell survival or death is determined remains unclear.In this study,we used a genome-wide association study(GWAS)to identify that a cluster of five Immune-associated nucleotide-binding protein(IAN)genes(IAN2 to IAN6)is responsible for variation in heat tolerance at the reproductive stage in Arabidopsis thaliana.These IAN genes have both unique and overlapping functions in the negative regulation of heat tolerance,and their loss of function singly or in combination confers increased heat tolerance,measured by a lower number of barren siliques and a higher seedling survival rate under heat.The loss of rice IAN1 gene function also leads to enhanced heat tolerance,suggesting a conserved function of plant IANs.Transcriptome analysis revealed enhanced expression of HSR and UPR genes,as well as reduced cell death,under heat and ER stress in the mutant of IAN6,a major effect member in Arabidopsis.Furthermore,the IAN proteins were found to promote cell death induced by heat stress,ER stress,and cell death-inducing molecules.Thus,the Arabidopsis IAN genes repress heat tolerance,probably through the HSR and UPR and by enhancing the cell death pathway.The IAN2 to IAN6 proteins are partially localized to the ER,suggesting a direct role in the UPR and UPR-mediated cell death.In addition,a natural IAN6 variant from more heat-tolerant Arabidopsis accessions confers greater heat tolerance and induces less cell death compared with the natural variant from less heat-tolerant accessions.The heat-tolerant IAN6 variant is associated with a higher maximum temperature of the warmest month at its collection sites compared with the heat-sensitive variant.Taken together,these results reveal an important role of Arabidopsis IAN2 to IAN6 genes in the regulation of the HSR,UPR,and cell death,and suggest that their natural variations have adaptive functions in heat tolerance. | Shan Lu Tianquan Zhu Zhixue Wang Lilin Luo Shuai Wang Minghui Lu Yongmei Cui Baohong Zou Jian Hua | 2021 | Molecular Plant2021，14，2： | 2 |
| 3 | Ethacrynic acid targets GSTM1 to ameliorate obesity by promoting browning of white adipocytes显示文摘Dear Editor,Obesity is caused by an imbalance between energy intake and expenditure,and has become a global epidemic with over 650 million adults affected.Adipose tissues in mammals are composed of white adipose tissue(WAT)and classical brown adipose tissue(BAT),and their balance is highly related to the occurrence of obesity.The browning of white adipocytes results in“beige”or“brite”adipocytes,which appear functionally similar to classical brown adipocytes,and can be detected in WAT deposits of animals that have been exposed to cold or other inducers(Fu et al.,2015). | Zhaomeng Cui Yang Liu Wei Wan Yuyan Xu Yehui Hu Meng Ding Xin Dou Ruina Wang Hailing Li Yongmei Meng Wei Li Wei Jiang Zengxia Li Yiming Li Minjia Tan Dengke KMa Yu Ding Jun OLiu Cheng Luo Biao Yu Qiqun Tang Yongjun Dang | 2021 | Protein & Cell2021，12，6： | 1 |
| 4 | The origin of remnant forest stands of Pinus tabulaeformis in southeastern Inner Mongolia显示文摘 | Hongyan Liu Haiting Cui Pengtao Yu Yongmei Huang | 2002 | Plant Ecology2002，，2： | 1 |
| 5 | Dental Imaging With Near-Infrared Transillumination Using Random Fiber Laser显示文摘Contrary to the conventional detection method like radiography,the near infrared light source has been demonstrated to be suitable for dental imaging due to different reflectivity among enamel,dentin,and caries lesion.In this paper,three light sources with different bandwidths based on a transillumination method are compared.The contrast among enamel,dentin,and caries lesion is calculated in different situations.The experimental results show that the random fiber laser has the best comprehensive quality in dental imaging due to its high spectral density,low coherence,and deep penetration.This work provides a guidance for light source selection in dental imaging. | Jiayu GUO Yunjiang RAO Weili ZHANG Zewen CUI Anran LIU Yongmei YAN | 2020 | Photonic Sensors2020，10，4： | 1 |
| 6 | The origin of remnant forest stands of Pinus tabulaeformis in southeastern Inner Mongolia显示文摘 | Hongyan Liu Haiting Cui Pengtao Yu Yongmei Huang | 2002 | Plant Ecology2002，，2： | 1 |
| 7 | Antimicrobial activity and biodiversity of endophytic fungi in Dendrobium devonianum and Dendrobium thyrsiflorum from Vietnam 显示文摘 | Xing Yongmei Chen Juan Cui Jinlong | 2011 | Current Microbiology2011，62，4： | 1 |
| 8 | Research on Financial Risk Identification and Assessment in Merger & Acquisition显示文摘 | Yongmei Cui Liwei Wang | 2005 | China-USA Business Review2005，4，5： | 1 |
| 9 | Design, synthesis, and characterization of BK channel openers based on oximation of abietane diterpene derivatives 显示文摘 | Yongmei Cui Eriko Yasutomi Yuko Otani | 2010 | Bioorganic & Medicinal Chemistry2010，10，： | 1 |
| 10 | Synthesis and application of a novel 9,9-diethyl-1,2-diaryl-1,9-dihydrofluoreno[2,3-d]imidazole for blue organic light emitting diode显示文摘Two novel 2-(4-(9,9-disubstitued-9 H-fluoren-2-yl)phenyl)-9,9-diethyl-l-phenyl-1,9-dihydrofluoreno-[2,3-d]imidazole derivatives 2 a and 2 b were synthesized and characterized.Their photophysical and electrochemical properties,thermal stability property,and electroluminescence(EL)performance of 2 b were investigated.The fabricated device based on 2 b doping into 4,4’-N,N’-dicarbazole-biphenyl(5%)as an emitter present a maximum brightness of 1272 cd/m^2 at 4 V with the CIE coordinate of(0.1590,0.0465). | Xueying Wang Zhangcheng Liao Tianqi Wang Haixia Lin Zixing Wang Yongmei Cui | 2020 | Chinese Chemical Letters2020，31，1： | 1 |
| 11 | Synthesis and Characterization of 9,9-diethyl-1-phenyl-1,9-dihydrofluoreno[2,3-d]imidazole-ended Fluorophores显示文摘A series ofπ-conjugated compounds ending with 9,9-diethyl-1-phenyl-1,9-dihydrofluoreno[2,3-d]imidazole were conveniently synthesized by condensation of the key intermediate9,9-diethyl-N^(2)-phenyl-9H-fluorene-2,3-diamine with the corresponding symmetric aryl phthalaldehydes under very mild conditions.The structures of these compounds were confirmed by^(1)H NMR,^(13)C NMR,and HRMS.Their UV-Vis spectroscopy data,fluorescent spectroscopy data,and further details of the electronic properties from cyclic voltammetry measurements and theoretical calculations were studied.Most compounds possess good fluorescence-emitting ability with quantum yield of fluorescence values in the region of 0.36-0.92 and display emission within 449-513 nm depending on the molecular nature. | LI Saijun WANG Tianqi TAN Qitao LIN Haixia CUI Yongmei | 2023 | Journal of Wuhan University of Technology(Materials Science)2023，38，6： | 0 |
| 12 | Development and commercial application of Baosteel sintering flue gas recirculating process显示文摘Because of the low temperature,large waste gas volume,high pollutant content,and complicated compositions,waste heat recovery and emission gas treatment of sintering flue gas have always presented a challenge in the steel industry,and this issue has attracted widespread attention both locally and abroad. Recently,based on the first domestic pilot plant and demonstration project,Baosteel has performed a series of innovative research and development investigations on its sintering flue gas recirculating( SFGR) process,in which the system design and optimization,dioxin-related contaminant source suppression,ore matching structure optimization,wear-resistant design of cycling fans and pipelines,high-efficiency dust removal equipment,system control and stable operation strategy,flue gas mixing and switching control,circular hood sealing,oxygen content conditioning,recirculation sintering system process control,and model development have been studied,and a complete set of equipment and technology for the SFGR process has been initially developed. The investigation results suggest that the SFGR process can not only significantly reduce exhaust gas volume and pollutant emissions but also recover low-temperature waste heat and reduce the energy consumption of sintering; therefore,the overall technologies possess great value in energy savings,pollution emission reduction,and sintering ore quality / yield improvement. | CUI Jian LI Xianwei SHI Lei DU Hongjin JIA Xiufeng XI Saifeng YU Bo WANG Ruyi YU Yongmei JIN Chun YANG Yun | 2014 | Baosteel Technical Research2014，8，4： | 0 |
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