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| 1 | Deep Learning for Wireless Physical Layer: Opportunities and Challenges显示文摘Machine learning(ML) has been widely applied to the upper layers of wireless communication systems for various purposes, such as deployment of cognitive radio and communication network. However, its application to the physical layer is hampered by sophisticated channel environments and limited learning ability of conventional ML algorithms. Deep learning(DL) has been recently applied for many fields, such as computer vision and natural language processing, given its expressive capacity and convenient optimization capability. The potential application of DL to the physical layer has also been increasingly recognized because of the new features for future communications, such as complex scenarios with unknown channel models, high speed and accurate processing requirements; these features challenge conventional communication theories. This paper presents a comprehensive overview of the emerging studies on DL-based physical layer processing, including leveraging DL to redesign a module of the conventional communication system(for modulation recognition, channel decoding, and detection) and replace the communication system with a radically new architecture based on an autoencoder. These DL-based methods show promising performance improvements but have certain limitations, such as lack of solid analytical tools and use of architectures that are specifically designed for communication and implementation research, thereby motivating future research in this field. | Tianqi Wang Chao-Kai Wen Hanqing Wang Feifei Gao Tao Jiang Shi Jin | 2017 | China Communications2017，14，11： | 51 |
| 2 | State-of-the-art review on frequency response of wind power plants in power systems显示文摘With an increasing penetration of wind power in the modern electrical grid, the increasing replacement of large conventional synchronous generators by wind power plants will potentially result in deteriorated frequency regulation performance due to the reduced system inertia and primary frequency response. A series of challenging issues arise from the aspects of power system planning,operation, control and protection. Therefore, it is valuable to develop variable speed wind turbines(VSWTs) equipped with frequency regulation capabilities that allow them to effectively participate in addressing severe frequency contingencies. This paper provides a comprehensive surveyon frequency regulation methods for VSWTs. It fully describes the concepts, principles and control strategies of prevailing frequency controls of VSWTs, including future development trends. It concludes with a performance comparison of frequency regulation by the four main types of wind power plants. | Ziping WU Wenzhong GAO Tianqi GAO Weihang YAN Huaguang ZHANG Shijie YAN Xiao WANG | 2018 | Journal of Modern Power Systems and Clean Energy2018，6，1： | 26 |
| 3 | Remote Sensing Monitoring of Gullies on a Regional Scale: A Case Study of Kebai Region in Heilongjiang Province, China显示文摘Gully erosion is one of the major causes of land degradation in most areas and attracts increasing attention from researchers. We monitored gullies in the Kebai region in Heilongjiang Province of China by using remote sensing data and found that gully density increased with the increase in slope when the slope was less than 3°. Gully density in sunny slopes or windward slopes was greater than in shady slopes or leeward slopes because of the impacts of freezing and thawing, wind and solar radiation. Specifically, the gully density in northeast slope was the greatest and in southwest was the smallest. Gully density was reduced with increasing slope length and the longer the slope length, the less the gully density changed between 1965 and 2005. Affected by runoff, gullies most easily to occur in concave slopes and the critical elevation for gully erosion was 250–275 m. Moreover, hilly regions had the greatest gully density, followed by tableland regions, whereas the gully density in flatlands was the lowest. However, the gully density of these three types of landforms all increased between 1945 and 2000, and the portion of increase was 57.45%(hill), 52.91%(mesa) and 25.32%(plain), respectively. | ZHANG Shuwen LI Fei LI Tianqi YANG Jiuchun BU Kun CHANG Liping WANG Wenjuan YAN Yechao | 2015 | Chinese Geographical Science2015，25，5： | 10 |
| 4 | Mass-transport Deposits of the Upper Cretaceous Qingshankou Formation, Songliao Terrestrial Basin, Northeast China: Depositional Characteristics, Recognition Criteria and External Geometry显示文摘Extensive mass transport deposits(MTDs), which form a significant component of the stratigraphic record in ancient and modern deep water systems, mostly distributed in the continental margin of ocean basins worldwide. To date, no large-scale MTDs have been found in Chinese terrestrial basins. Based on integrated analysis of the seismic, drilling, core and logging data, this article report MTDs have been found in Songliao terrestrial basin(SLTB), Northeast China. During the depositional period of the Upper Cretaceous Qingshankou Formation, slope break of lacustrine basins was an ideal discharge place for gravity depositions. Regional sedimentary study of MTDs reveals that Cretaceous-age MTDs in SLTB were deposited in slope-break environments by slide, slump and debris flow, and MTDs were mixed with little turbidite simultaneously. Besides the massive aspect, key features of MTDs are the common presence of deformational structures or softsedimentary deformation, floating shale clasts, boudins, microfaults, distortion beddings, rotated sand debris. Detailed mapping of two three-dimensional(3-D) seismic surveys acquired in Yingtai(YT) and Haituozi(HTZ) areas reveals that MTDs are characterized by chaotic, mounded, and transparent seismic reflection. Growth fault, slope gully and geomorphology of the slope break greatly influenced the sedimentary process and external geometry of MTDs, and as a consequence, MTDs in SLTB exhibit classic fan-like geometry and some special(non-fan-like) external geometry. Furthermore, fanlike MTDs can be divided into three subcategories, including isolated fan, mother-son fan and stacked fan. Non-fan-like MTDs can be divided into two subcategories, strip-like MTDs and faulted-pit MTDs. A new sedimentary model has been built for MTDs in SLTB. MTDs have become a new exploration and development target in the SLTB. | PAN Shuxin WEI Pingsheng WANG Tianqi LIU Caiyan CHEN Bintao LIANG Sujuan | 2014 | Acta Geologica Sinica(English Edition)2014，88，1： | 9 |
| 5 | The role of miR156 in developmental transitions in Nicotiana tabacum显示文摘Plants undergo a series of developmental transitions during their life cycle. After seed germination, plants pass through two distinct phases: the vegetative phase in which leaves are produced and the reproductive phase in which flowering occurs. Based on the reproductive competence and morphological changes, the vegetative phase can be further divided into juvenile and adult phases. Here, we demonstrate that the difference between juvenile and adult phase of Nicotiana tabacum is characterized by the changes in leaf size, leaf shape as well as the number of leaf epidermal hairs(trichomes). We further show that miR156, an age-regulated microR NA, regulates juvenile-to-adult phase transition in N. tabacum. Overexpression of miR156 results in delayed juvenile-to-adult transition and flowering. Together, our results support an evolutionarily conserved role of miR156 in plant developmental transitions. | ZHANG TianQi WANG JiaWei ZHOU ChuanMiao | 2015 | Science China(Life Sciences)2015，58，3： | 7 |
| 6 | Release of VEGF and BMP9 from injectable alginate based composite hydrogel for treatment of myocardial infarction显示文摘Myocardial infarction(MI)is one of cardiovascular diseases that pose a serious threat to human health.The pathophysiology of MI is complex and contains several sequential phases including blockage of a coronary artery,necrosis of myocardial cells,inflammation,and myocardial fibrosis.Aiming at the treatment of different stages of MI,in this work,an injectable alginate based composite hydrogel is developed to load vascular endothelial active factor(VEGF)and silk fibroin(SF)microspheres containing bone morphogenetic protein 9(BMP9)for releasing VEGF and BMP9 to realize their respective functions.The results of in vitro experiments indicate a rapid initial release of VEGF during the first few days and a relatively slow and sustained release of BMP9 for days,facilitating the formation of blood vessels in the early stage and inhibiting myocardial fibrosis in the long-term stage,respectively.Intramyocardial injection of such composite hydrogel into the infarct border zone of mice MI model via multiple points promotes angiogenesis and reduces the infarction size.Taken together,these results indicate that the dual-release of VEGF and BMP9 from the composite hydrogel results in a collaborative effect on the treatment of MI and improvement of heart function,showing a promising potential for cardiac clinical application. | Yong Wu Tianqi Chang Weiqian Chen Xiaoyu Wang Jingjing Li Yueqiu Chen You Yu Zhenya Shen Qian Yu Yanxia Zhang | 2021 | Bioactive Materials2021，6，2： | 7 |
| 7 | Spontaneous apoptosis of cells in therapeutic stem cell preparation exert immunomodulatory effects through release of phosphatidylserine显示文摘Mesenchymal stem cell(MSC)-mediated immunomodulation has been harnessed for the treatment of human diseases,but its underlying mechanism has not been fully understood.Dead cells,including apoptotic cells have immunomodulatory properties.It has been repeatedly reported that the proportion of nonviable MSCs in a MSC therapeutic preparation varied from 5-50%in the ongoing clinical trials.It is conceivable that the nonviable cells in a MSC therapeutic preparation may play a role in the therapeutic effects of MSCs.We found that the MSC therapeutic preparation in the present study had about 5%dead MSCs(DMSCs),characterized by apoptotic cells.Namely,1×10^(6) MSCs in the preparation contained about 5×10^(4) DMSCs.We found that the treatment with even 5×10^(4) DMSCs alone had the equal therapeutic effects as with 1×10^(6) MSCs.This protective effect of the dead MSCs alone was confirmed in four mouse models,including concanavalin A(ConA)-and carbon tetrachloride(CCI4)-induced acute liver injury,LPS-induced lung injury and spinal cord injury.We also found that the infused MSCs died by apoptosis in vivo.Furthermore,the therapeutic effect was attributed to the elevated level of phosphatidylserine(PS)upon the injection of MSCs or DMSCs.The direct administration of PS liposomes(PSLs)mimic apoptotic cell fragments also exerted the protective effects as MSCs and DMSCs.The Mer tyrosine kinase(MerTK)deficiency or the knockout of chemokine receptor C-C motif chemokine receptor 2(CCR2)reversed these protective effects of MSCs or DMSCs.These results revealed that DMSCs alone in the therapeutic stem cell preparation or the apoptotic cells induced in vivo may exert the same immunomodulatory property as the'living MSCs preparation'through releasing PS,which was further recognized by MerTK and participated in modulating immune cells. | Xuemei He Weiqi Hong Jingyun Yang Hong Lei Tianqi Lu Cai He Zhenfei Bi Xiangyu Pan Yu Liu Lunzhi Dai Wei Wang Canhua Huang Hongxin Deng Xiawei Wei | 2021 | Signal Transduction and Targeted Therapy2021，6，8： | 6 |
| 8 | Performance of the Autism Spectrum Rating Scale and Social Responsiveness Scale in Identifying Autism Spectrum Disorder Among Cases of Intellectual Disability显示文摘The Autism Spectrum Rating Scale(ASRS) and the Social Responsiveness Scale(SRS) have been widely used for screening autism spectrum disorder(ASD) in the general population during epidemiological studies, but studies of individuals with intellectual disability(ID) are quite limited. Therefore, we recruited the parents/caregivers of 204 ASD cases, 71 ID cases aged 6–18 years from special education schools, and 402 typically developing(TD) children in the same age span from a communitybased population to complete the ASRS and SRS. The results showed that the ID group scored significantly lower on total and subscale scores than the ASD group on both scales(P \ 0.05) but higher than TD children(P \ 0.05).Receiver operating characteristic analyses demonstrated a similar fair performance in discriminating ASD from ID with the ASRS(area under the curve(AUC) = 0.709,sensitivity = 77.0%, specificity = 52.1%, positive predictive value(PPV) = 82.2%) and the SRS(AUC = 0.742,sensitivity = 59.8%, specificity = 77.5%, PPV = 88.4%).The results showed that individuals with ID had clear autistic traits and discriminating ASD from ID cases was quite challenging, while assessment tools such as ASRS and SRS, help to some degree. | Chunpei Li Hao Zhou Tianqi Wang Shasha Long Xiaonan Du Xiu Xu Weili Yan Yi Wang | 2018 | Neuroscience Bulletin2018，34，6： | 5 |
| 9 | Small molecules in targeted cancer therapy:advances,challenges,and future perspectives显示文摘Due to the advantages in efficacy and safety compared with traditional chemotherapy drugs,targeted therapeutic drugs have become mainstream cancer treatments.Since the first tyrosine kinase inhibitor imatinib was approved to enter the market by the US Food and Drug Administration(FDA)in 2001,an increasing number of small-molecule targeted drugs have been developed for the treatment of malignancies.By December 2020,89 small-molecule targeted antitumor drugs have been approved by the US FDA and the National Medical Products Administration(NMPA)of China.Despite great progress,small-molecule targeted anti-cancer drugs still face many challenges,such as a low response rate and drug resistance.To better promote the development of targeted anti-cancer drugs,we conducted a comprehensive review of small-molecule targeted anti-cancer drugs according to the target classification.We present all the approved drugs as well as important drug candidates in clinical trials for each target,discuss the current challenges,and provide insights and perspectives for the research and development of anti-cancer drugs. | Lei Zhong Yueshan Li Liang Xiong Wenjing Wang Ming Wu Ting Yuan Wei Yang Chenyu Tian Zhuang Miao Tianqi Wang Shengyong Yang | 2021 | Signal Transduction and Targeted Therapy2021，6，6： | 5 |
| 10 | Abscisic acid signaling negatively regulates nitrate uptake via phosphorylation of NRT1.1 by SnRK2s in Arabidopsis显示文摘Nitrogen(N)is a limiting nutrient for plant growth and productivity.The phytohormone abscisic acid(ABA)has been suggested to play a vital role in nitrate uptake in fluctuating N environments.However,the molecular mechanisms underlying the involvement of ABA in N deficiency responses are largely unknown.In this study,we demonstrated that ABA signaling components,particularly the three subclass Ⅲ SUCROSE NON-FERMENTING1(SNF1)-RELATED PROTEIN KINASE 2 S(SnRK2)proteins,function in root foraging and uptake of nitrate under N deficiency in Arabidopsis thaliana.The snrk2.2 snrk2.3 snrk2.6 triple mutant grew a longer primary root and had a higher rate of nitrate influx and accumulation compared with wild-type plants under nitrate deficiency.Strikingly,SnRK2.2/2.3/2.6 proteins interacted with and phosphorylated the nitrate transceptor NITRATE TRANSPORTER1.1(NRT1.1)in vitro and in vivo.The phosphorylation of NRT1.1 by SnRK2 s resulted in a significant decrease of nitrate uptake and impairment of root growth.Moreover,we identified NRT1.1Ser585 as a previously unknown functional site:the phosphomimetic NRT1.1S585 D was impaired in both low-and high-affinity transport activities.Taken together,our findings provide new insight into how plants fine-tune growth via ABA signaling under N deficiency. | Hang Su Tian Wang Chuanfeng Ju Jinping Deng Tianqi Zhang Mengjiao Li Hui Tian Cun Wang | 2021 | Journal of Integrative Plant Biology2021，63，3： | 4 |
| 11 | Traditional Chinese Medicines alleviated myocardial ischemia by regulating Qi and promoting blood circulation显示文摘OBJECTIVE:To investigate the efficacy of Chinese medicines on Qi stagnation and blood stasis in rats with myocardial ischemia.METHODS:Fifty male Wistar rats were randomly divided into five groups(n=10)as follows:(a)sham operation(Sham),(b)myocardial ischemia(Model),(c)treatment that regulates Qi(Qi),(d)treatment that promotes blood circulation(Blood),(e)treatment that both regulates Qi and promotes blood circulation(QB).The rat model was established via activities restriction for 6 h followed by tail clamp stimulation for 5 mins every day for 7 d and occlusion left coronary anterior descending artery.Afterwards rats were treated with medicines that regulate Qi and/or promote blood circulation via gavage for 14 d.Behavioral parameters were evaluated using open field and elevated plus-maze tests.The tongue color and sublingual vein were visually examined.Blood flow perfusion of tongue and auricle were detected using PIMⅡ.The mesenteric microcirculation was examined via capillaroscopy,and hemodynamics was assessed using a polygraph system.Serum homocysteine(Hcy),creatine kinase isoenzyme(CKMB)levels and endothelin-1(ET-1)were measured.Hematoxylin and eosin staining and transmission electron microscopy were employed to detect the myocardial morphology and ultrastructure,respectively.RESULTS:Compared with findings in Sham group,rats in model group had coarse hair,dark mucosa of the lips and claw,low activity,and increased anxiety.Compared with findings in Model group,rats in the three treatment groups exhibited a lighter tongue color without an extended and varicose sublingual vein.There were significant increases of auricle blood flow perfusion in the Qi group and tongue bottom blood flow perfusion in the QB group.Compared with findings in Model rats,rats in Blood group exhibited improved mesenteric microcirculation associated with increased mesenteric blood flow and a larger arteriole diameter.Moreover,compared with findings in Model rats,Qi and QB rats exhibited increased left ventricular±dp/dtmax,decreased serum CKMB,Hcy,ET-1 levels,and reduced myocardial ultrastructural damage.CONCLUSION:Myocardial ischemia damage was suppressed by Traditional Chinese Medicines that regulate Qi and promote blood circulation. | Wang Chen Wang Xiaoreng Tao Tianqi Song Dandan Wang Jianli Wang You Liu Xiuhua Wu Xudong | 2020 | Journal of Traditional Chinese Medicine2020，40，6： | 4 |
| 12 | New direction of arrival estimation method for wideband coherent signals显示文摘To estimate the direction-of-arrival (DOA) of wideband coherent signals, a new method by modifying the orthogonality of the projected subspaces method is proposed. And it can deal with randomly position perturbed arrays by using the Toeplitz method. This method needn't the primary information of DOA for focusing matrix and the sector dividing of interpolated method, which improving the precision of estimation and reducing the computational complexity. Simulations illustrate the effectiveness of this method. | Wang Ling Yin Jihao Chen Tianqi | 2008 | Journal of Systems Engineering and Electronics2008，19，3： | 4 |
| 13 | PEG-assisted Hydrothermal synthesis and photoluminescence of CdMoO 4 :Tb 3+ green phosphor显示文摘 | Junjun Zhang Tianqi Zhao Bingnan Wang Linlin Li Lianchun Zou Shucai Gan | 2014 | Journal of Physics and Chemistry of Solids2014，，： | 4 |
| 14 | A nanotheranostic agent based on Nd^(3+)-doped YVO_(4) with blood-brain-barrier permeability for NIR-Ⅱ fluorescence imaging/magnetic resonance imaging and boosted sonodynamic therapy of orthotopic glioma显示文摘The specific diagnosis and treatment of gliomas is a primary challenge in clinic due to their high invasiveness and blood-brain barrier(BBB)obstruction.It is highly desirable to find a multifunctional agent with good BBB penetration for precise theranostics.Herein,we design and construct a core-shell structured nanotheranostic agent(YVO_(4):Nd^(3+)-HMME@MnO_(2)-LF,marked as YHM)with YVO_(4)∶Nd^(3+) particles as the core and MnO_(2) nanosheets as the shell.Sonosensitizer hematoporphyrinmonomethyl ether(HMME)and lactoferrin(LF)were further loaded and modified on the surface,giving it a good ability to cross the BBB,near-infrared fluorescence imaging in the second window(NIR-Ⅱ)/magnetic resonance imaging(MRI)bimodality,and highly efficient sonodynamic therapy(SDT)of orthotopic gliomas.The YVO_(4):Nd^(3+)(25%)core exhibited good NIR-Ⅱ fluorescence properties,enabling YHM to act as promising probes for NIR-Ⅱ fluorescence imaging of vessels and orthotopic gliomas.MnO_(2) shell can not only provide O2 in the tumor microenvironments(TME)to significantly improve the healing efficacy of SDT,but also release Mn^(2+) ions to achieve T1-weight MRI in situ.Non-invasive SDT can effectively restrain tumor growth.This work not only demonstrates that multifunctional YHM is promising for diagnosis and treatment of orthotopic glioma,but also provides insights into exploring the theranostic agents based on rare earth-doped yttrium vanadate nanoparticles. | Zhijia Lv Longhai Jin Yue Cao Hao Zhang Dongzhi Xue Na Yin Tianqi Zhang Yinghui Wang Jianhua Liu Xiaogang Liu Hongjie Zhang | 2022 | Light(Science & Applications)2022，11，6： | 3 |
| 15 | 采用改进的一次浸泡和碳化法制备多层碳纳米管/棉织物柔性超级电容器电极显示文摘基于简便有效的方法制备了一种导电率高、电化学参数优良的多层碳纳米管(MWCNTs-COOH)/棉织物柔性超级电容器电极。首先,通过改进的一次性浸泡法(Improved one-time dipping method)将MWCNTs-COOH装载到棉织物上,且高温和高压下处理2 h能有效增加其在基层上的紧密度。其次,在高温下对上述制备好的复合材料进行预氧化和碳化以提高其碳含量。由此获得的复合材料具备高导电性和较大的比表面积。电化学分析结果显示,该复合材料在电流比0.81 A·g-1时的最大比电容达到94.3 F·g-1。经3 000次不同角度的弯折后,其展示出良好的稳定性和用作柔性超级电容器电极的巨大潜能。 | 杨子山 Hao Tianqi Sun Jiayi Wang Wei | 2018 | 中国棉花2018，45，10： | 3 |
| 16 | The Arabidopsis catalase triple mutant reveals important roles of catalases and peroxisome-derived signaling in plant development显示文摘Hydrogen peroxide(H_2O_2)is generated in many metabolic processes.As a signaling molecule,H_2O_2plays important roles in plant growth and development,as well as environmental stress response.In Arabidopsis,there are three catalase genes,CAT1,CAT2,and CAT3.The encoded catalases are predominately peroxisomal proteins and are critical for scavenging H_2O_2.Since CAT1 and CAT3 are linked on chromosome 1,it has been almost impossible to generate cat1/3 and cat1/2/3 mutants by traditional genetic tools.In this study,we constructed cat1/3 double mutants and cat1/2/3 triple mutants by CRISPR/Cas9 to investigate the role of catalases.The cat1/2/3 triple mutants displayed severe redox disturbance and growth defects under physiological conditions compared with wild-type and the cat2/3 double mutants.Transcriptome analysis showed a more profound transcriptional response in the cat1/2/3 triple mutants compared to the cat2/3 mutants.These differentially expressed genes are involved in plant growth regulation as well as abiotic and biotic stress responses.In addition,expression of OXI1(OXIDATIVE SIGNAL INDUCIBLE 1)and several MAPK cascade genes were changed dramatically in the catalase triple mutant,suggesting that H_2O_2produced in peroxisomes could serve as a peroxisomal retrograde signal. | Tong Su Pingping Wang Huijuan Li Yiwu Zhao Yao Lu Peng Dai Tianqi Ren Xiaofeng Wang Xuezhi Li Qun Shao Dazhong Zhao Yanxiu Zhao Changle Ma | 2018 | Journal of Integrative Plant Biology2018，60，7： | 3 |
| 17 | Analysis of process variations impact on the single-event transient quenching in 65 nm CMOS combinational circuits显示文摘Single-event transient pulse quenching(Quenching effect)is employed to effectively mitigate WSET(SET pulse width).It enhanced along with the increased charge sharing which is norm for future advanced technologies.As technology scales,parameter variation is another serious issue that significantly affects circuit’s performance and single-event response.Monte Carlo simulations combined with TCAD(Technology Computer-Aided Design)simulations are conducted on a six-stage inverter chain to identify and quantify the impact of charge sharing and parameter variation on pulse quenching.Studies show that charge sharing induce a wider WSET spread range.The difference of WSET range between no quenching and quenching is smaller in NMOS(N-Channel Metal-Oxide-Semiconductor Field-Effect Transistor)simulation than that in PMOS’(P-Channel Metal-Oxide-Semiconductor Field-Effect Transistor),so that from parameter variation view,quenching is beneficial in PMOS SET mitigation.The individual parameter analysis indicates that gate oxide thickness(TOXE)and channel length variation(XL)mostly affect SET response of combinational circuits.They bring 14.58%and 19.73%average WSET difference probabilities for no-quenching cases,and 105.56%and 123.32%for quenching cases. | WANG TianQi XIAO LiYi ZHOU Bin QI ChunHua | 2014 | Science China(Technological Sciences)2014，57，2： | 2 |
| 18 | Recent Advances on Porous Materials for Synergetic Adsorption and Photocatalysis显示文摘Porous photocatalysts are promising materials capable of simultaneously adsorbing and oxidizing/reducing target species,showing great potentials in environmental remediation and energy generation.This review offered a comprehensive overview of the recent progress in design,fabrication,and applications of porous photocatalysts,including carbon-based semiconductors,metal oxides/sulfides,metal–organic frameworks,and adsorbent–photocatalyst hybrids.The fundamental understanding of the structure–performance relationships of porous materials together with the in-depth insights into the synergetic effects between adsorption and photocatalysis was presented.The strategies to further improve the photocatalytic activity of porous photocatalysts were proposed.This review would provide references and outlooks of constructing efficient porous materials for adsorptive and photocatalytic removal of pollutants and energy production. | Tianqi Wang Bingbing Tian Bin Han Dingren Ma Mingzhe Sun Aamir Hanif Dehua Xia Jin Shang | 2022 | Energy & Environmental Materials2022，5，3： | 2 |
| 19 | Identifying the Optimal Age for Herpes Zoster Vaccination—Yichang City,Hubei Province,China,2017–2019显示文摘Summary What is already known about this topic?Herpes zoster(shingles)is a common skin condition in older adults,which usually presents as a painful rash with blisters.Vaccination is the most effective method to prevent shingles.However,there is not sufficient population-based epidemiological data in China to optimize the timing of zoster vaccination.What is added by this report?Clustering analyses of population-wide epidemiological data from the Healthcare Big Data Platform in Yichang,China showed that the average annual zoster incidence is the highest among people 55 years or older,at 10 cases per thousand persons per year,making this age group the optimal target population for vaccination.Incidence was lower but increased with age among younger adults,28–54 years old.What are the implications for public health practice?With limited vaccination resources,zoster vaccinations should be targeted at adults 55 years or older who are at the greatest risk for shingles.Research should be conducted to understand the risk of shingles among young and middle-aged adults and identify triggers of shingles:potentially leading to preventive measures. | Meiying You Tianqi Wang Miaomiao Wang Wei Jiang Jing Jiang Xudong Li Yuehua Hu Dapeng Yin | 2022 | China CDC weekly2022，4，29： | 2 |
| 20 | Electrospun Scaff old of Collagen and Polycaprolactone Containing ZnO Quantum Dots for Skin Wound Regeneration显示文摘Nanofibers(NFs)have been widely used in tissue engineering such as wound healing.In this work,the antibacterial ZnO quantum dots(ZnO QDs)have been incorporated into the biocompatible poly(ε-caprolactone)/collagen(PCL/Col)fibrous scaffolds for wound healing.The as-fabricated PCL-Col/ZnO fibrous scaffolds exhibited good swelling,antibacterial activity,and biodegradation behaviors,which were beneficial for the applications as a wound dressing.Moreover,the PCL-Col/ZnO fibrous scaffolds showed excellent cytocompatibility for promoting cell proliferation.The resultant PCL-Col/ZnO fibrous scaffolds containing vascular endothelial growth factor(VEGF)also exhibited promoted wound-healing effect through promoting expression of transforming growth factor-β(TGF-β)and the vascular factor(CD31)in tissues in the early stages of wound healing.This new electrospun fibrous scaffolds with wound-healing promotion and antibacterial property should be convenient for treating wound healing. | Pengfei Li Liming Ruan Ruofan Wang Tianqi Liu Gao Song Xiaofei Gao Guohua Jiang Xiaoyan Liu | 2021 | Journal of Bionic Engineering2021，18，6： | 2 |
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