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| 1 | Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine显示文摘 | Tingting Zhu Ian A Roundtree Ping Wang Xiao Wang Li Wang Chang Sun Yuan Tian Jie Li Chuan He Yanhui Xu | 2014 | Cell Research2014，24，12： | 28 |
| 2 | Chronology and Geochemistry of the Nadingcuo Volcanic Rocks in the Southern Qiangtang Region of the Tibetan Plateau:Partial Melting of Remnant Ocean Crust along the Bangong-Nujiang Suture显示文摘计算碱的岩石主要 trachyte 和 trachyandesite 填写了的 Nadingcuo high-K 是在在西藏的高原的南部的 Qiangtang 岩层的暴烈的岩石的最大的露头区域。然而,他们的准确来源和 peterogenesis 仍然被辩论。40Ar-39Ar 和 LAM-ICPMS 锆石 U-Pb 同位素的标明日期证实这些岩石爆发了在始新世。另外, Nadingcuo 暴烈的岩石被高 Sr/Y 内容比率描绘,与从海洋的外壳的部分融化导出的 adakite 类似。他们能进一步作为高 Mg#(Mg#= 4857 ) 和低 Mg#(Mg#= 3342 ) 被分类子类型。Nadingcuo adakitic 岩石有相对低(87Sr/86Sr ) 我和高 Nd (t) ,显示出类似的一个趋势到在 Bangong-Nujiang 海洋的外壳中在场的 Dongcuo ophiolite。简单建模显示 Nadingcuo adakitic 岩石是与 10%20% 源于 Bangong-Nujiang 海洋的暗岩的混合拉萨岩层的外壳的材料。在这些底上,我们建议低 Mg# Nadingcuo adakitic 岩石是残余的部分融化的产品有小沉积的海洋的外壳,和高 Mg# 岩石是在升起之间的反应的结果残余融化有 subducted 的海洋的外壳沉积和披风楔。因此, Nadingcuo adakitic 岩石的起源可能与印度亚洲的碰撞在新生代期间触发的 intracontinental subduction 有关。 | WANG Baodi CHEN Jianlin XU Jifeng WANG Liquan ZENG Qinggao DONG Yanhui | 2010 | Acta Geologica Sinica(English Edition)2010，84，6： | 15 |
| 3 | PD-L1 is a direct target of cancer-FOXP3 in pancreatic ductal adenocarcinoma(PDAC),and combined immunotherapy with antibodies against PD-L1 and CCL5 is effective in the treatment of PDAC显示文摘High expression of PD-L1 marks the poor prognosis of pancreatic ductal adenocarcinomas(PDAC).However,the regulatory mechanism of PD-L1 remains elusive.We recently reported that cancer Forkhead box protein 3(Cancer-FOXP3 or C-FOXP3)promoted immune evasion of PDAC by recruiting Treg cells into PDAC via upregulation of CCL5.In this study,we confirmed that PD-L1 was overexpressed in PDAC samples from two independent cohorts of patients with radical resection.Moreover,C-FOXP3 was colocalized and correlated with the expression of PD-L1 in tumor cells at the mRNA and protein levels,and this finding was confirmed by the The Cancer Genome Atlas(TCGA)database.Chromatin immunoprecipitation(ChIP)revealed that C-FOXP3 directly bound to the promoter region of PD-L1 in pancreatic cancer cells.Furthermore,overexpression of C-FOXP3 activated the luciferase reporter gene under the control of the PD-L1 promoter.However,mutation of the binding motif-a completely reversed the luciferase activity.In addition,C-FOXP3-induced upregulation of PD-L1 effectively inhibited the activity of CD8+T cells.Based on our recent finding that the CCL-5 antibody achieved a better response to PDAC models with high C-FOXP3 levels,we further demonstrated that the PD-L1 antibody strengthened the antitumor effect of CCL-5 blockade in xenograft and orthotopic mouse models with high C-FOXP3 levels.In conclusion,C-FOXP3 directly activates PD-L1 and represents a core transcription factor that mediates the immune escape of PDAC.Combined blockade of PD-L1 and CCL-5 may provide an effective therapy for patients with PDAC that have high C-FOXP3 levels. | Xiuchao Wang Xin Li Xunbin Wei Haiping Jiang Chungen Lan Shengyu Yang Han Wang Yanhui Yang Caijuan Tian Zanmei Xu Jiangyan Zhang Jihui Hao He Ren | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 11 |
| 4 | Changing Forestry Policy by Integrating Water Aspects into Forest/Vegetation Restoration in Dryland Areas in China显示文摘Restoration forestry (forest rehabilitation) or re-vegetation is one effective measure to solve environmental problems, notably soil erosion. It may be further stimulated by the Clean Development Mechanism for carbon sequestration. However, there is an intensive and on-going debate about the adverse effects arising from afforestation in dryland areas, such as soil drying up which may cause further damage to the success of forest restoration, and the water yield reduction from watershed which may harm the regional development. On other hand, some preliminary studies showed a possibility that these adverse effects may be diminished more or less by properly designing the system structure and spatial distribution of forest/vegetation in a watershed. However, it is urgent to develop an evidence-based and sustainable new forestry policy for harmonizing forest-water interrelation. As a leading country in afforestation, China is beginning to develop a more trans-disciplinary and cross-sectoral forestry policy for harmonizing forestry development with water management. The main points of the changing new forestry policy should include: (1) Establishing a regional development strategy focusing on harmonized forest-water relations; (2) Taking forest-water interactions as an important part of evaluation; (3) Reducing the 'eco-water' quota of forests through technical advancement; (4) Developing and extending water-adaptive forest management practices; (5) Strengthening forest ecohydrological research and decision support ability. | WANG Yanhui Mike Bonell Karl-Heinz Feger YU Pengtao XIONG Wei XU Lihong | 2012 | Bulletin of the Chinese Academy of Sciences2012，26，1： | 9 |
| 5 | Cryo-EM structure of human mTOR complex 2显示文摘 | Xizi Chen Mengjie Liu Yuan Tian Jiabei Li Yilun Qi Dan Zhao Zihan Wu Min Huang Catherine C. L. Wong Hong-Wei Wang Jiawei Wang Huirong Yang Yanhui Xu | 2018 | Cell Research2018，28，5： | 8 |
| 6 | Cryo-EM structure of human DNA-PK holoenzyme显示文摘 | Xiaotong Yin Mengjie Liu Yuan Tian Jiawei Wang Yanhui Xu | 2017 | Cell Research2017，27，11： | 8 |
| 7 | 4.4 A Resolution Cryo-EM structure of human mTOR Complex 1显示文摘 | Huirong Yang Jia Wang Mengjie Liu Xizi Chen Min Huang Dan Tan Meng-Qiu Dong Catherine C. L, Wong Jiawei Wang Yanhui Xu Hong-Wei Wang | 2016 | Protein & Cell2016，7，12： | 7 |
| 8 | Water yield reduction due to forestation in arid mountainous regions, northwest China显示文摘Forestation has been encouraged worldwide due to increasing demand for forest products, and for its ecological benefits such as soil erosion control and sediment reduction. However, forestation reduces runoff, thus potentially aggravating water shortages in arid regions. In order to quantitatively estimate the possible water yield reductions caused by forestation in an arid region, a small watershed (the Pailugou watershed) in the Qilian Mountains of northwest China was chosen as a study area. The responses of hydrological dynamics to different forestation scenarios in the study area were simulated using the TOPOG model. The results showed that forestation could lead to a complete loss of runoff at the site scale. At the watershed scale, a 10% increase in forest coverage led to a runoff reduction of 25.6 mm, equivalent to 13% of the runoffin the un-forested watershed. However, due to climatological and topographical constraints, the potential forest distribution occupied only 46.3% of the watershed area, and runoff reduction was estimated to reach a maximum of 60% when the forest cover ratio increased from 0.41% to 46.1%. Actual forest coverage is 36% in the study area, thus the water yield will be reduced with any further increase in forest area. Our study suggested that a trade-off between the numerous benefits of forest coverage increase and its negative impact on water yield should be carefully addressed in arid regions with inherently severe water-shortage. | Pengtao YU Yanhui WANG Xudong WU Xiaohong DONG Wei XIONG Gaowa BU Shunli WANG Jinye WANG Xiande LIU Lihong XU | 2010 | International Journal of Sediment Research2010，25，4： | 7 |
| 9 | Synergy between metallic components of MoNi alloy for catalyzing highly efficient hydrogen storage of MgH2显示文摘Catalysts play a critical role in improving the hydrogen storage kinetics in Mg/MgH2 system.Exploring highly efficient catalysts and catalyst design principles are hot topics but challenging.The catalytic activity of metallic elements on dehydrogenation kinetics generally follows a sequence of Ti>Nb>Ni>V>Co>Mo.Herein,we report a highly efficient alloy catalyst composed of low-active elements of Mo and Ni(i.e.MoNi alloy)for MgH2 particles.MoNi alloy nanoparticles show excellent catalytic effect,even outperforming most advanced Ti-based catalysts.The synergy between Mo and Ni elements can promote the break of Mg-H bonds and the dissociation of hydrogen molecules,thus significantly improves the kinetics of Mg/MgH2 system.The MoNi-catalyzed Mg/MgH2 system can absorb and release 6.7 wt.%hydrogen within 60 s and 10 min at 300℃,respectively,and exhibits excellent cycling stability and low-temperature hydrogen storage performance.This study provides a strategy for designing efficient catalysts for hydrogen storage materials using the synergy of metal elements. | Meng Chen Yanhui Pu Zhenyang Li Gang Huang Xiaofang Liu Yao Lu Wukui Tang Li Xu Shuangyu Liu Ronghai Yu Jianglan Shui | 2020 | Nano Research2020，13，8： | 5 |
| 10 | Preparation of alumina supported on carbon nano-tubes and its application in fluoride adsorption from an aqueous solution显示文摘A novel material, alumina supported on carbon nanotubes (Al2O3/CNT), was prepared from carbon nano-tubes and A1(NO3)3. X-ray diffraction (XRD) spectra demonstrate that alumina is amorphous, and scanning electron microscope (SEM) images show that CNT and alumina are homogeneously mixed. Furthermore, the fluoride adsorption behavior on the surface of Al2O3/CNT has been investigated and compared with other adsorbents. The results indicate that Al2O3/CNT has a high adsorption capacity, with a saturation adsorption capacity of 39.4 mg/g. It is also found that the adsorption capacity of Al2O3/CNT is 3.0-4.5 times that of γ-Al2O3 while almost equal to that of IRA-410 polymeric resin at 25°C . The adsorption isotherms of fluoride on Al2O3/CNT fit the Freundlich equation well, and optimal pH ranging from 5.0 to 9.0. | WANG Shuguang LI Yanhui ZHAO Dan XU Cailu LUAN Zhaokun LIANG Ji WU Dehai | 2002 | Chinese Science Bulletin2002，47，9： | 5 |
| 11 | Cryo-EM structure of human ATR-ATRIP complex显示文摘ATR (变异毛细管扩张、 Rad3 相关的混乱) 蛋白质 kinase 并且(交往 ATR 蛋白质) 起锚形成建筑群并且响应复制应力和 DNA 损坏起一个关键作用。这里,我们决定了在 4.7 点 ATR 起锚复杂的人的 cryo 电子显微镜学(他们) 结构吗?分辨率并且造了 ATR 的 C 终端催化核心的一个原子模型(残余 1 521-2 644 ) 在 3.9 点?分辨率。建筑群采用空心形状,由在不同符合构造的二 ATR 单体组成。他们地图为起锚表明 14 热在扩大 S 形状重复。ATR 的 conformational 灵活性起锚允许适当地锁二 ATR 单体的 N 终点赞成 ATR 起锚复杂的形成和功能的差异。孤立的头头和尾巴尾巴各个采用假 2 褶层对称。外面的催化衣袋脸和底层存取没被禁止的元素限制。我们的研究为理解集会提供一个结构的基础 ATR 起锚,为描绘调停 ATR 的 DNA 的建筑群和一个框架修理小径。 | Qinhui Rao Mengjie Liu Yuan Tian Yuhan Hao Lei Song Zhaoyu Qin Chen Ding Hong-Wei Wang Jiawei Wang Yanhui Xu | 2018 | Cell Research2018，28，2： | 4 |
| 12 | Large-Scale Discovery of Non-conventional Peptides in Maize and Arabidopsis through an Integrated Peptidogenomic Pipeline显示文摘Non-conventional peptides(NCPs),which include small open reading frame-encoded peptides,play critical roles in fundamental biological processes.In this study,we developed an integrated peptidogenomic pipeline using high-throughput mass spectra to probe a customized six-frame translation database and applied it to large-scale identification of NCPs in plants.A total of 1993 and 1860 NCPs were unambiguously identified in maize and Arabidopsis,respectively.These NCPs showed distinct characteristics compared with conventional peptides and were derived from introns,3′UTRs,5′UTRs,junctions,and intergenic regions.Furthermore,our results showed that translation events in unannotated transcripts occur more broadly than previously thought.In addition,we found that dozens of maize NCPs are enriched within regions associated with phenotypic variations and domestication selection,indicating that they potentially are involved in genetic regulation of complex traits and domestication in maize.Taken together,our study developed an integrated peptidogenomic pipeline for large-scale identification of NCPs in plants,which would facilitate global characterization of NCPs from other plants.The identification of large-scale NCPs in both monocot(maize)and dicot(Arabidopsis)plants indicates that a large portion of plant genome can be translated into biologically functional molecules,which has important implications for functional genomic studies. | Shunxi Wang Lei Tian Haijun Liu Xiang Li Jinghua Zhang Xueyan Chen Xingmeng Jia Xu Zheng Shubiao Wu Yanhui Chen Jianbing Yan Liuji Wu | 2020 | Molecular Plant2020，13，7： | 4 |
| 13 | USP47-mediated deubiquitination and stabilization of YAP contributes to the progression of colorectal cancer显示文摘Dear Editor,The Hippo tumor suppressor pathway plays an important role in development and tumorigenesis.Yes-associated protein(YAP)is a major effector of the Hippo pathway regulating the expression of genes involved in cell proliferation,cell death,and cell differentiation(Pan,2010;Johnson and Haider,2014;Piccolo etal.,2014;Yu etal.,2015).In intestine,YAP is mainly expressed in leucine rich repeat containing G protein-coupled receptor 5(LGR5)marked stem cells,and is required for regeneration following tissue damage and the development of colon cancer in mice(Cai etal.,2010;Barry etal.,2013;Wang etal.,2017).Moreover,in colorectal cancer(CRC)specimens,elevated YAP expression and activity is frequently observed(Steinhardt et al.,2008).It has been shown that high YAP expression is associated with cancer metastasis,poor prognosis,resistance to chemotherapy,and greater possibility of relapse(Johnson and Haider,2014;Yu etal.,2015). | Beiqing Pan Yi Yang Jian Li Yu Wang Chuantao Fang Fa-Xing Yu Yanhui Xu | 2020 | Protein & Cell2020，11，2： | 4 |
| 14 | Genome-wide comprehensive analysis of transcriptomes and small RNAs offers insights into the molecular mechanism of alkaline stress tolerance in a citrus rootstock显示文摘Alkaline stress has serious-negative effects on citrus production.Ziyang xiangcheng(Citrus junos Sieb.ex Tanaka)(Cj)is a rootstock that is tolerant to alkaline stress and iron deficiency.Trifoliate orange(Poncirus trifoliata(L.)Raf.)(Pt),the most widely used rootstock in China,is sensitive to alkaline stress.To investigate the molecular mechanism underlying the tolerance of Cj to alkaline stress,next-generation sequencing was employed to profile the root transcriptomes and small RNAs of Cj and Pt seedlings that were cultured in nutrient solutions along a three pH gradient.This two-level regulation data set provides a system-level view of molecular events with a precise resolution.The data suggest that the auxin pathway may play a central role in the inhibitory effect of alkaline stress on root growth and that the regulation of auxin homeostasis under alkaline stress is important for the adaptation of citrus to alkaline stress.Moreover,the jasmonate(JA)pathway exhibits the opposite response to alkaline stress in Cj and Pt and may contribute to the differences in the alkaline stress tolerance and iron acquisition between Cj and Pt.The dataset provides a wealth of genomic resources and new clues to further study the mechanisms underlying alkaline stress resistance in Cj. | Juxun Wu Junying Cao Mei Su Guizhi Feng Yanhui Xu Hualin Yi | 2019 | Horticulture Research2019，6，1： | 4 |
| 15 | A study on the changes of dynamic feature code when fixing bugs: towards the benefits and costs of Python dynamic features显示文摘Dynamic features in programming languages support the modification of the execution status at runtime, which is often considered helpful in rapid development and prototyping. However, it was also reported that some dynamic feature code tends to be change-prone or error-prone. We present the first study that analyzes the changes of dynamic feature code and the roles of dynamic features in bug-fix activities for the Python language. We used an AST-based differencing tool to capture fine-grained source code changes from 17926 bug-fix commits in 17 Python projects. Using this data, we conducted an empirical study on the changes of dynamic feature code when fixing bugs in Python. First, we investigated the characteristics of dynamic feature code changes, by comparing the changes between dynamic feature code and non-dynamic feature code when fixing bugs, and comparing dynamic feature changes between bug-fix and non-bugfix activities. Second, we explored 226 bug-fix commits to investigate the motivation and behaviors of dynamic feature changes when fixing bugs. The study results reveal that(1) the changes of dynamic feature code are significantly related to bug-fix activities rather than non-bugfix activities;(2) compared with non-dynamic feature code, dynamic feature code is inserted or updated more frequently when fixing bugs;(3) developers often insert dynamic feature code as type checks or attribute checks to fix type errors and attribute errors;(4) the misuse of dynamic features introduces bugs in dynamic feature code, and the bugs are often fixed by adding a check or adding an exception handling. As a benefit of this paper, we gain insights into the manner in which developers and researchers handle the changes of dynamic feature code when fixing bugs. | Zhifei CHEN Wanwangying MA Wei LIN Lin CHEN Yanhui LI Baowen XU | 2018 | Science China(Information Sciences)2018，61，1： | 4 |
| 16 | Cloning and analysis of a cDNA encoding acetohydroxy acid isomeroreductase from G2 pea显示文摘Using cDNA representational difference analysis (cDNA RDA) method, we have successfully isolated a gene fragment whose expression was specifically induced by external GAa application. Screening a G2 pea cDNA library using this fragment as a probe, we obtained a 2036 bp full-length cDNA. It contains a 1746 bp open reading frame and encodes a protein of 581 amino acids with a theoretical molecular weight of 64 ku. It shares high-level sequenceidentity with AAIR genes from other plant species. This cDNA was cloned into expression vector and recombinant E. coli DH5α cells with remarkable AAIR enzyme activity were obtained. | XU Huasong XU Yunjian GU Xuesong HU Tingzhang SU Yanhui ZHU Yuxian | 2001 | Chinese Science Bulletin2001，46，21： | 4 |
| 17 | Sub-synchronous frequency domain-equivalent modeling for wind farms based on rotor equivalent resistance characteristics显示文摘The equivalent simplification of large wind farms is essential for evaluating the safety of power systems.However,sub-synchronous oscillations can significantly affect the stability of power systems.Although detailed mathematical models of wind farms can help accurately analyze the oscillation mechanism,the solution process is complicated and may lead to problems such as the“dimensional disaster.”Therefore,this paper proposes a sub-synchronous frequency domain-equivalent modeling method for wind farms based on the nature of the equivalent resistance of the rotor,in order to analyze sub-synchronous oscillations accurately.To this end,Matlab/Simulink is used to simulate a detailed model,a single-unit model,and an equivalent model,considering a wind farm as an example.A simulation analysis is then performed under the sub-synchronous frequency to prove that the model is effective and that the wind farm equivalence model method is valid. | Yanhui Xu Tianchu Gao | 2022 | Global Energy Interconnection2022，5，3： | 4 |
| 18 | Efficacy and brain mechanism of transcutaneous auricular vagus nerve stimulation for adolescents with mild to moderate depression:Study protocol for a randomized controlled trial显示文摘Background Depression is a common mental illness in childhood and adolescence,with an incidence of 4%–5%;it can lead to impairments in learning and social functioning.Transcutaneous auricular vagus nerve stimulation(taVNS)is a commonly used method of auricular acupuncture point stimulation,which is regarded as an effective treatment for adults with depression.The aim of this study was to investigate the efficacy and mechanism of taVNS for adolescents with mild to moderate depression.Methods This randomized controlled clinical trial will include 120 patients aged 12–16 years,all of whom are diagnosed with mild to moderate depression.Patients will be randomly assigned to a taVNS group and a drug control group(sertraline hydrochloride)at a ratio of 1:1.Patients will be evaluated using the 17‐item Hamilton Depression Scale,Hamilton Anxiety Rating Scale,Self‐Rating Depression Scale,Self‐Rating Anxiety Scale,and Pittsburgh Sleep Quality Index scores at baseline,as well as at the 2nd,4th,6th,8th,and 12th weeks.To investigate the underlying neural mechanisms of taVNS treatment from the perspective of the default mode network,multimodal magnetic resonance imaging(MRI;i.e.,structural MRI[sMRI],resting state MRI[rsMRI],and pseudocontinuous arterial spin‐labeled[pcASL]MRI)will be used to compare cerebral images among groups.MRI data will also be collected from 40 healthy volunteers to assess whether the participants exhibit normal development of structural and functional components.Discussion Depression is the most common mental disorder in adolescence.Drug treatment can improve depression symptoms;however,the side effects of drug treatments are often severe.This study proposes a simple physiotherapy that aims to treat adolescents with mild to moderate depression.The mechanism of taVNS in the treatment of depression will also be investigated.The results of this study will provide evidence to guide the application of taVNS in adolescents with depression. | Xue Xiao Xiaobing Hou Zhangjing Zhang Ying Li Xue Yu Yanhui Wang Jing Tian Ke Xu | 2020 | Pediatric Investigation2020，4，2： | 3 |
| 19 | Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans显示文摘Histone 离氨酸 methylation 能被 JmjC 包含域的蛋白质在 sequence-state-specific 和 methylation-state-specific 举止移开。然而,底层特性怎么样,决定,酶怎么被调整,大部分是未知的。我们最近发现了那 ceKDM7A,一个哲学博士 -- 并且 JmjC 包含域的蛋白质,是为 H3K9me2 特定的 histone demethylase, H3K27me2,和 PHD 摸绑定到 H3K4me3 指南在 vivo 的 demethylation 活动。为了为酶的活动和 PHD 的功能提供结构的卓见进分子的机制,摸,我们与包含 H3K4me3, H3K9me2,和 H3K27me2 修正的各种各样的联合的单身者或二肽一起在 apo 形式并且在建筑群解决了酶的六水晶结构。结构显示 H3K9me2 和 H3K27me2 以一种类似的方式与 ceKDM7A 交往,并且肽绑定特性被特定的相互作用的一个网络决定。结构的几何测量也揭示了与 PHD 手指和 H3K9me2 界限联系到 JmjC 领域的那 H3K4me3 从二个分开的分子,建议 trans-histone 肽绑定机制。因此,我们的全身的结构的研究重要地由催化领域而且更多揭示底层识别不仅,为 H3K9me2 和 H3K27me2 的 ceDKM7A 的双特性的分子的机制。 | Ying Yang Lulu Hu Ping Wang Haifeng Hou Yan Lin Yi Liu Ze Li Rui Gong Xiang Feng Lu Zhou Wen Zhang Yuhui Dong Huirong Yang Hanqing Lin Yiqin Wang Charlie Degui Chen Yanhui Xu | 2010 | Cell Research2010，20，8： | 3 |
| 20 | The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B显示文摘KDM5B 是 histone H3K4me2/3 demethylase。KDM5B 的 PHD1 领域为 demethylation 是批评的,但是位于这个领域的行动下面的机制是不清楚的。在这份报纸,我们观察了那 PHD1 < 潜水艇 class= “ a-plus-plus ” > KDM5B 与 unmethylated H3K4me0 交往。我们 PHD1 的 NMR 结构 < 潜水艇 class= “ a-plus-plus ” > 在有 H3K4me0 的建筑群的 KDM5B 表明有约束力的模式与另外的报导哲学博士手指的稍微不同。由在接口(L325A/D328A ) 的残余上的两倍变化的这个相互作用的混乱减少在在约 50% 的房间和增加的 KDM5B 的 H3K4me2/3 demethylation 活动肿瘤 suppressor 基因由的 transcriptional 压抑近似双重。这些调查结果暗示那 PHD1 < 潜水艇 class= “ a-plus-plus ” > KDM5B 可以帮助在目标基因维持 KDM5B 调停 KDM5B 的 demethylation 活动。 | Yan Zhang Huirong Yang Xue Guo Naiyan Rong Yujiao Song Youwei Xu Wenxian Lan Xu Zhang Maili Liu Yanhui Xu Chunyang Cao | 2014 | Protein & Cell2014，5，11： | 3 |
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