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11篇 您的检索式:作者名="Changmin WU"
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1Wearable Sweat Biosensors Refresh Personalized Health/Medical Diagnostics显示文摘Sweat contains a broad range of critical biomarkers including ions,small molecules,and macromolecules that may indirectly or directly reflect the health status of the human body and thereby help track disease progression.Wearable sweat biosensors enable the collection and analysis of sweat in situ,achieving real-time,continuous,and noninvasive monitoring of human biochemical parameters at the molecular level.This review summarizes the physiological/pathological information of sweat and wearable sweat biosensors.First,the production of sweat pertaining to various electrolytes,metabolites,and proteins is described.Then,the compositions of the wearable sweat biosensors are summarized,and the design of each subsystem is introduced in detail.The latest applications of wearable sweat biosensors for outdoor,hospital,and family monitoring are highlighted.Finally,the review provides a summary and an outlook on the future developments and challenges of wearable sweat biosensors with the aim of advancing the field of wearable sweat monitoring technology.Wenhui Ji Jingyu Zhu Wanxia Wu Nanxiang Wang Jiqing Wang Jiansheng Wu Qiong Wu Xuewen Wang Changmin Yu Gaofeng Wei Lin Li Fengwei Huo 2021Research2021,,1:1
2Wearable Sweat Biosensors Refresh Personalized Health/Medical Diagnostics显示文摘Sweat contains a broad range of critical biomarkers including ions,small molecules,and macromolecules that may indirectly or directly reflect the health status of the human body and thereby help track disease progression.Wearable sweat biosensors enable the collection and analysis of sweat in situ,achieving real-time,continuous,and noninvasive monitoring of human biochemical parameters at the molecular level.This review summarizes the physiological/pathological information of sweat and wearable sweat biosensors.First,the production of sweat pertaining to various electrolytes,metabolites,and proteins is described.Then,the compositions of the wearable sweat biosensors are summarized,and the design of each subsystem is introduced in detail.The latest applications of wearable sweat biosensors for outdoor,hospital,and family monitoring are highlighted.Finally,the review provides a summary and an outlook on the future developments and challenges of wearable sweat biosensors with the aim of advancing the field of wearable sweat monitoring technology.Wenhui Ji Jingyu Zhu Wanxia Wu Nanxiang Wang Jiqing Wang Jiansheng Wu Qiong Wu Xuewen Wang Changmin Yu Gaofeng Wei Lin Li Fengwei Huo 2022Research2022,,1:1
3Mitochondria-targeted fluorescent probe based on vibration-induced emission for real-time monitoring mitophagy-specific viscosity dynamic显示文摘Directly monitoring mitophagy-specific viscosity dynamic in living cells is of great significance but remains challenging.Herein,this study reported a novel mitochondria-targeted fluorescent probe DPACDY based on vibration-induced emission(VIE)for monitoring viscosity changes during mitochondrial autophagy.This probe contained N,N’-diphenyl-dihydrodibenzo[a,c]phenazine(DPAC)as the VIE core and two positively charged pyridinium moieties for mitochondria anchoring.As the ambient viscosity increased,the vibration of DPAC-DY could be hindered,and subsequently resulting in the enhancement of fluorescence emission.In vitro and intracellular experiments indicated that the probe DPAC-DY showed highly sensitive response to viscosity due to VIE mechanism.Importantly,by virtue of this probe,in situ and real-time visualization of the specific viscosity dynamics during the mitochondrial autophagy process was achieved.Thus,this work provides a novel strategy for VIE-based viscosity response sensors applied to specific organelles and offers a platform for in-depth study of mitochondrial viscosity-related diseases.Shuangxi Wang Bicong Zhou Na Wang Changmin Yu Naidi Yang Jian Chen Qiong Wu Chengwu Zhang Lin Li Wei Huang 2020Chinese Chemical Letters2020,31,11:1
4Nd3-xAExFe5O12: Hydrothermal Synthesis, Structure and Magnetic Properties显示文摘WU Jie YUAN Long WANG Shan HOU Changmin 2017Chemical Research in Chinese Universities2017,33,6:0
5Growth of Nd : YAG Free from Core and Dislocation显示文摘Nd:YAG crystals free from core and dislocation have been grown by using the“controlled reversion of solid-liquid interface” method.The basic idea of the method is to combine the respective advantages of both the convex and the flat interface growth and to overpass 'safely'the interface reversion so that the whole crystal could be grown in stable fluid How states.XU Tianhua WU Zihe PENG Weiqing ZHEN Qimeng ZHOU Jianmin ZHANG Shengxiu XIE Sanwen XU Guangyu HANG Changmin 1993Chinese Physics Letters1993,10,11:0
6Migration of paleo-uplift in southwestern Tarim Basin and its implications for orogenesis and reservoir development, NW China显示文摘Based on well horizon calibration,the typical seismic profiles in southwestern Tarim Basin were interpreted systematically,regional geological sections were established,and the regional denudation thickness of each tectonic period was restored.On this basis,the plane morphology maps of ancient structures of the Cambrian pre-salt dolomites in different periods were compiled,and the spatial distribution,development,evolution and migration of paleo-uplift in the late Early Paleozoic were analyzed.In the late Early Paleozoic,there existed a unified regional paleo-uplift widely distributed in southwestern Tarim Basin,which is called the southwestern Tarim plaeo-uplift.The“Tarim SW paleo-uplift”and“Hetian paleo-uplift”proposed in previous literatures are not independent,but the result of the spatio-temporal migration and evolution of the southwestern Tarim paleo-uplift identified in this paper.The southwestern Tarim paleo-uplift emerged at the end of Middle Ordovician,and took its initial shape with increased amplitude in the Late Ordovician.During the Silurian,the southwestern Tarim paleo-uplift rose steadily and expanded rapidly to the east,incorporating Pishan-Hetian and other areas,with the structural high locating in the Pishan-Hetian area.During the Devonian,the southwestern Tarim paleo-uplift began to shrink gradually,to a limited range in the Pishan-Hetian area in the southern part of the basin.During the Carboniferous,the southwestern Tarim paleo-uplift became an underwater uplift,that is,the paleo-uplift gradually died out.The southwestern Tarim paleo-uplift belongs to the forebulge of the southwestern Tarim foreland basin in the late Early Paleozoic,and its formation and evolution are related to the early Paleozoic orogeny of the West Kunlun orogenic belt in the south of the Tarim Basin.The migration of the southwestern Tarim paleo-uplift from the northwestern part of the southwestern Tarim Basin to the Pishan-Hetian area indicates the early Paleozoic orogenic process of the West Kunlun orogenic belt,which started in the western section at the end of Middle Ordovician and extended from west to east in a“scissor”style.The migration and evolution of the southwestern Tarim paleo-uplift controlled the development of unconformities at the end of Middle Ordovician,the end of Late Ordovician,and the end of Middle Devonian,and the spatial distribution of dissolved fracture-cave reservoirs in weathered crust below the unconformities in the southwest of Tarim Basin.The migration of the structural high of the southwestern Tarim paleo-uplift also played an important role in controlling the development of dissolved fracture-cave reservoirs in weathered crust.YAN Jiakai CHEN Hanlin CHENG Xiaogan CHEN Yongquan ZENG Changmin CHEN Cai WU Hongxiang 2023Petroleum Exploration and Development2023,50,1:0
7Ultrasensitive detection of IgE levels based on magnetic nanocapturer linked immunosensor assay for early diagnosis of cancer显示文摘Rapid and accurate detection of immunoglobulin E(Ig E) in serum and reduction of serum dosage are of great significance for clinical detection. Herein, we described a rapid magnetic separation of Ig E from patient serum based on Fe3 O4@Si O2-NTA@026 sdab as the capture probe and multiple horseradish peroxidase(HRP)-labeled antibodies linked gold nanoparticles(Au NPs) as chemiluminescence(CL) signal amplifier for ultrasensitive detection of total Ig E. Results showed that the limit of detection of our immunosensor system in serum samples was 0.03 k U/L, which is lowest in comparison with current methods, and far lower than that of Immuno CAP for Ig E detection(0.1 k U/L). Furthermore, our immunosensor possessed satisfied repeatability and accuracy, as well as good stability. In comparison with the Immuno CAP for the quantitative detection of Ig E, highly consistent results were achieved in 20 serum samples. Specially, this method was also successfully utilized for assessing the Ig E traces in breast cancer patients,which provides a new idea for the diagnosis of early cancer. Therefore, we believe that such versatile immunosensor will offer an alternative method for the on-site monitoring and determination of various Ig E-related diseases.Yongxin Liu Mengda Cao Zhongxi Huang Changmin Yu Naidi Yang Qiong Wu Liang Shi Wenjie Duan Yi Zhu Jifu Wei Lin Li Wei Huang 2022Chinese Chemical Letters2022,33,4:0
8Rational design of nanocarriers for mitochondria-targeted drug delivery显示文摘Well-developed mitochondria-targeted nanocarriers for function regulation are highly desirable.Numerous studies have been conducted on the treatment of mitochondria-related diseases;however,further improvements are required to develop more effective drug delivery methods.Herein,we comprehensively introduce recent developments progress in rational design of mitochondria-targeted nanocarriers,and discuss the different strategies of available nanocarriers for targeting mitochondria.We also highlight the advantages and disadvantages of various carrier systems that are currently in use.Finally,perspective on new generation for mitochondria-targeted delivery systems in the emerging area of drug-based therapeutics is also discussed.Lihua Huang Zonghao Sun Qian Shen Zhongxi Huang Shuangxi Wang Naidi Yang Gongqiang Li Qiong Wu Wei Wang Lin Li Changmin Yu 2022Chinese Chemical Letters2022,33,9:0
9Improved Energy Conversion Efficiency of ZnO/Polythiophene Solar Cell in Ga-Doped ZnO Nanorod Array Photoanode显示文摘We reported the fabrication and doping effect of Ga-doped ZnO nanorods/electropolymerized polythio-phene(e-PT) hybrid photovoltaic(h-PV) devices. Ga-Doped ZnO nanorod array photoanode devices were fabricatedvia hydrothermally growing nanorods on sol-gel spin-coating ZnO seed layer, and then the nanorod array was im-mersed into a thiophene solution to yield a thin polythiophene film by electrochemically polymerization. Afterwards,a thin layer of A1 was deposited on the surface of polythiophene to make an electrode for photovoltaic measurement.The ZnO nanorods with different Ga-doping contents were characterized by means of X-ray diffraction(XRD), scan-ning electron micrograph(SEM) and X-ray photoelectron spectroscopy(XPS). Photovoltaic J-V characterization wasperformed on the e-PT/ZnO bilayer and bulk heterojunction(BHJ) devices. Though the unsubstituted polythiophene isnot an ideal polymer material for solar cells with high power conversion efficiency, it is a sound model for the studyon the effect of dopant in hybrid materials. The results indicate that doping Ga can substantially improve the powerconversion efficiency of the ZnO-polythiophene solar cell.WU Jie LIU Huanhuan YUAN Long HOU Changmin 2016Chemical Research in Chinese Universities2016,32,6:0
10Detailed analysis of PCBs and PCDD/Fs impurities in a dielectric oil sample (ASKAREL Nr 1740) from an imported transformer in China显示文摘Jun HUANG Yamei HUI Toru MATSUMURA Gang YU Shubo DENG Makoto YAMAUCHI Changmin WU Norimasa YAMAZAKI 2014Frontiers of Environmental Science & Engineering2014,8,2:0
11Genome-wide identification and prediction of long noncoding RNAs in half-smooth tongue sole Cynoglossus semilaevis显示文摘At present,the function and profile of long noncoding RNAs(lncRNAs)in half-smooth tongue soles Cynoglossus semilaevis remain poorly understood.Therefore,we identified lncRNAs in the species using large-scale deep sequencing approaches.A total of 96726222 clean reads and 2497 lncRNAs were obtained from the compound samples.In total,1694 known lncRNAs and 803 novel lncRNAs were identified.Most of the novel lncRNAs distributed mainly in a range of 200-3000 nt and contained 2-6 exons.Six novel lncRNAs were selected for expression analysis by quantitative reverse transcription-polymerase chain reaction,of which lnc_770 and lnc_150 were expressed mainly in the ovary.This study provides a valuable resource for lncRNA studies of half-smooth tongue sole and improves our understanding of the function of non-coding RNA in fish.JIANG Xiaoli JING Xiaohong LÜ Yan SHAN Changmin LI Jiahua YU Yan WU Yuyong SUN Yeying 2020Journal of Oceanology and Limnology2020,38,1:0
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