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| 1 | Activation of mitogen-activated protein kinases in satellite glial cells of the trigeminal ganglion contributes to substance P-mediated inflammatory pain显示文摘Inflammatory orofacial pain,in which substance P (SP) plays an important role,is closely related to the cross-talk between trigeminal ganglion (TG) neurons and satellite glial cells (SGCs).SGC activation is emerging as the key mechanism underlying inflammatory pain through different signalling mechanisms,including glial fibrillary acidic protein (GFAP) activation,phosphorylation of mitogen-activated protein kinase (MAPK) signalling pathways,and cytokine upregulation.However,in the TG,the mechanism underlying SP-mediated orofacial pain generated by SGCs is largely unknown.In this study,we investigated whether SP is involved in inflammatory orofacial pain by upregulating interleukin (IL)-1β and tumour necrosis factor (TNF)-α from SGCs,and we explored whether MAPK signalling pathways mediate the pain process.In the present study,complete Freund’s adjuvant (CFA) was injected into the whisker pad of rats to induce an inflammatory model in vivo.SP was administered to SGC cultures in vitro to confirm the effect of SP.Facial expression analysis showed that pre-injection of L703,606 (an NK-1 receptor antagonist),U0126 (an inhibitor of MAPK/extracellular signal-regulated kinase [ERK] kinase [MEK] 1/2),and SB203580 (an inhibitor of P38) into the TG to induce targeted prevention of the activation of the NK-1 receptor and the phosphorylation of MAPKs significantly suppressed CFA-induced inflammatory allodynia.In addition,SP promoted SGC activation,which was proven by increased GFAP,p-MAPKs,IL-1β and TNF-α in SGCs under inflammatory conditions.Moreover,the increase in IL-1β and TNF-α was suppressed by L703,606,U0126 and SB203580 in vivo and in vitro.These present findings suggested that SP,released from TG neurons,activated SGCs through the ERK1/2 and P38 pathways and promoted the production of IL-1β and TNF-α from SGCs,contributing to inflammatory orofacial pain associated with peripheral sensitization. | Yanyan Zhang Ning Song Fei Liu Jiu Lin Mengke Liu Chaolan Huang Daqing Liao Cheng Zhou Hang Wang Jiefei Shen | 2019 | International Journal of Oral Science2019，11，3： | 6 |
| 2 | Remediation Technology for Combined Pollution of Lead and Cadmium in Farmland Soil显示文摘At present,the problem of heavy metal pollution in farmland in southern China is serious. Especially,the cadmium and lead are two heavy metal elements with serious pollution and great harm to human body. This paper reviewed some common methods and materials used in the control of cadmium and lead pollution in farmland soil. Then,it discussed the problems in the repair of cadmium and lead pollution in farmland soil. It came up with the future research direction,to provide references for remediation of lead and cadmium pollution in farmland soil. | Jun TAN Yongxian LIU Xiangfeng WEI Yanfei HUANG Liumei XIONG Liping PAN Jinping CHEN Bin LIU Chaolan ZHANG | 2018 | Asian Agricultural Research2018，10，9： | 3 |
| 3 | Surface-enhanced Raman scattering within silver- nanoparticle - decorated nanometric apertures 显示文摘 | Bei Nie Chaolan He Lijuan Liu | 2013 | Journal of Raman Spectroscopy2013，44，11： | 1 |
| 4 | Study on Thermal Deformation Measurement of Optical RemoteSensing Satellite Platform Based on Machine Vision显示文摘To solve the special requirements of the high orbit optical remote sensing satellite for the thermal deformation of the platform the thermal deformation test and measurement scheme of the satellite platform is designed. Through the comparative analysis of test results the rationality of the thermal deformation design of the platform structure is verified. The results of thermal deformation measurement show that the maximum deformation of A camera mounting surface is 57.5〃 and the maximum deformation of B camera mounting surface points to 79.3〃 which can be used as the basis for thermal deformation prediction of satellite during the orbit operation. | Jie Huang Chaolan You Peng Hou Da Luo Xiangsen Kong Xin Fu | 2019 | Journal of Harbin Institute of Technology(New Series)2019，26，5： | 1 |
| 5 | Assessment of metals pollution on agricultural soil surrounding a lead-zinc mining area in the Karst region of Guangxi, China显示文摘 | ZHANG Chaolan LI Zhongyi YANG Weiwei | 2013 | Bulletin of Environmental Contamination and Toxicology2013，90，6： | 1 |
| 6 | Analysis of factors influencing cardiopulmonary resuscitation and survival outcome in adults after in-hospital cardiac arrest:a retrospective observational study显示文摘To the Editor:Cardiopulmonary resuscitation(CPR)guidelines,especially the latest 2020 guidelines issued by the American Heart Association(AHA),have emphasized the importance of high-quality CPR.[1]The research on cardiac arrest(CA)and CPR has dramatically increased in recent years,and the international recovery guidelines are also being revised and implemented.However,the outcome of in-hospital cardiac arrest(IHCA)remains poor,and the understanding of the prognostic factors for survival outcome after IHCA is lacking,especially in China.Patients with CA are often poorly treated,and the incidence and mortality of CA are increasing yearly.[2]This study analyzed the effects of CPR,and explored the factors that affect survival outcome after IHCA in adults. | Chaolan Wang Yulei Gao Yancun Liu Ying Yao Chen Li Qingsong Li Yanfen Chai | 2022 | Chinese Medical Journal2022，135，23： | 1 |
| 7 | Confirmation of three inflammatory bowel disease susceptibility loci in a Chinese cohort显示文摘 | Chaolan Lv Xiaoming Yang Yiyang Zhang Xinmei Zhao Zhengyan Chen Jinghua Long Yingchun Zhang Changqing Zhong Jia Zhi Guopeng Yao Bo Jiang Fachao Zhi | 2012 | International Journal of Colorectal Disease2012，，11： | 1 |
| 8 | Assessment of metal pollution on agricultural soil surrounding a lead-zinc mining area in the Karst Region of Guangxi, China 显示文摘 | Zhang Chaolan Li Zhongyi Yang Weiwei | 2013 | Bulle- tin of Environmental Contamination and Toxicology2013，90，6： | 1 |
| 9 | Mercury contaminated and its potential health effects in a lead-zinc mining area in the karst region of Guangxi, China 显示文摘 | DENG Ghaohing ZHANG Chaolan LI Lihe | 2011 | Appl Geochem2011，26，2： | 1 |
| 10 | Modeling study of a flexible hub-beam system with large motion and with considering the effect of shear deformation显示文摘 | You Chaolan Hong Jiazhen Cai Guoping | 2006 | Journal of Sound and Vibration2006，295，1： | 1 |
| 11 | Edge Detection of COVID-19 CT Image Based on GF_SSR, Improved Multiscale Morphology, and Adaptive Threshold显示文摘Edge detection is an effective method for image segmentation and feature extraction.Therefore,extracting weak edges with the inhomogeneous gray of Corona Virus Disease 2019(COVID-19)CT images is extremely important.Multiscale morphology has been widely used in the edge detection of medical images due to its excellent boundary detection accuracy.In this paper,we propose a weak edge detection method based on Gaussian filtering and singlescale Retinex(GF_SSR),and improved multiscale morphology and adaptive threshold binarization(IMSM_ATB).As all the CT images have noise,we propose to remove image noise by Gaussian filtering.The edge of CT images is enhanced using the SSR algorithm.In addition,based on the extracted edge of CT images using improved Multiscale morphology,a particle swarm optimization(PSO)algorithm is introduced to binarize the image by automatically getting the optimal threshold.To evaluate our method,we use images from three datasets,namely COVID-19,Kaggle-COVID-19,and COVID-Chestxray,respectively.The average values of results are worthy of reference,with the Shannon information entropy of 1.8539,the Precision of 0.9992,the Recall of 0.8224,the F-Score of 1.9158,running time of 11.3000.Finally,three types of lesion images in the COVID-19 dataset are selected to evaluate the visual effects of the proposed algorithm.Compared with the other four algorithms,the proposed algorithm effectively detects the weak edge of the lesion and provides help for image segmentation and feature extraction. | Shouming Hou Chaolan Jia Kai Li Liya Fan Jincheng Guo Mackenzie Brown | 2022 | Computer Modeling in Engineering & Sciences2022，，7： | 0 |
| 12 | An overview on transparent ceramics with pyrochlore and fluorite structures显示文摘Transparent ceramics have potential applications in various areas,including aerospace,relativistic optics industries,medical cares and defense.Specifically,they can be used as laser gain media,armor windows,IR domes,solid-state phosphors,scintillators and electro-optical components.From crystal structure point of view,transparent ceramic materials should have high crystallographic symmetries(cubic,tetragonal and hexagonal),which have minimal birefringent effect.Currently,transparent ceramics are dominantly based on oxide materials,although there are also nonoxides,such as fluorides and nitrides(oxynitrides).Transparent ceramics with pyrochlore and fluorite structures have attracted much attention in recent years,whereas fluorides are not well described in the open literature.Therefore,this paper is aimed to deliver an overview on the progress of the two categories of transparent ceramics,from material processing and characterization point of view. | Yu He Kaige Liu Bingxi Xiang Chaolan Zhou Ling Zhang Gang Liu Xiaoyang Guo Jianpang Zhai Tao Li Ling Bing Kong | 2020 | Journal of Advanced Dielectrics2020，10，3： | 0 |
| 13 | Identification of Xunxi Shujin Decoction by TLC显示文摘[Objectives]To establish a TLC qualitative method for the determination of Radix Aconiti,Radix Aconiti Kusnezoffii,Caesalpinia sappan L.and Radix zanthoxyli.[Methods]TLC was used to study the quality of Radix Aconiti,Radix Aconiti Kusnezoffii and C.sappan L.in Xunxi Shujin Decoction,and the influencing factors were investigated to optimize the TLC conditions.[Results]In the TLC identification test of Radix Aconiti,Radix Aconiti Kusnezoffii,C.sappan L.and R.zanthoxyli in Xunxi Shujin Decoction,the spots were clear,the resolution was good,the specific value was moderate,the negative control was not disturbed,and the specificity was strong.[Conclusions]The established TLC method was simple,specific and reproducible,and could be used for the quality control of Xunxi Shujin Decoction. | Fengxian ZHAO Yuanming ZHONG Deren LI Yong CHEN Chaolan WANG Jian CUI | 2024 | Medicinal Plant2024，15，1： | 0 |
| 14 | The KL system in wheat permits homoeologous crossing over between closely related chromosomes显示文摘The Chinese wheat landrace Kaixianluohanmai(KL)expresses the ph-like phenotype.A major QTL,QPh.sicau-3A(syn.phKL),responsible for this effect has been mapped to chromosome arm 3AL.This study presents some characteristics of homoeologous pairing and recombination induced by phKL.In KL haploids,the level of homoeologous pairing was elevated relative to Ph1 Chinese Spring(CS)haploids.There was a clear preference for A–D pairing and less frequent for A–B and B–D,reflecting the higher levels of affinity between genomes A and D in wheat.The characteristics of pairing were affected by temperature and magnesium ion supplementation.The suitability of phKL for chromosome engineering was tested on three pairs of homoeologues:2Sv-2B,2Sv-2D,and 2RL-2BL.The recombination rates were 1.68%,0.17%,and 0%,respectively.The phKL locus in KL induced a moderate level of homoeologous chromosome pairing and recombination when the Ph1 locus of wheat was present,both in wheat haploids and hexaploids.The Ph1-imposed criteria for chromosome pairing and crossing over were relaxed to some degree,permitting homoeologous crossing over but only between closely related chromosomes;there was no crossing over between more differentiated chromosomes.Therefore,the phKL system(QPh.sicau-3A)can be a useful tool in chromosome engineering of wheat to transfer genes from closely related species with the benefit of reduced genomic chaos generated by the ph1b mutation. | Chaolan Fan Jiangtao Luo Jiaojiao Sun Hong Chen Liqiong Li Lanyue Zhang Xue Chen Yazhou Li Shunzong Ning Zhongwei Yuan Bo Jiang Lianquan Zhang Xuejiao Chen Adam J.Lukaszewski Dengcai Liu Ming Hao | 2023 | The Crop Journal2023，11，3： | 0 |
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