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| 1 | Risk assessment and validation of flood disaster based on fuzzy mathematics显示文摘Floods often take place around rivers and plains,which indicates a higher risk of flooding in these areas.This paper adopts fuzzy comprehensive assessment(FCA),simple fuzzy classification(SFC),and the fuzzy similarity method(FSM) to assess flood disaster risk in Kelantan,Malaysia.Validation data,such as the flooded area,paddy area,urban area,residential area,and refuges,were overlaid to validate and analyze the accuracy of flood disaster risk.The results show that(1) 70-75% of flooded areas lie within the higher and high-est risk zones,which shows an effective assessment accuracy;(2) paddy,built-up,and residential areas concentrated in the higher and highest risk zones are more likely to be destroyed by flood disasters;(3) 200-225 refuges in the higher and highest risk zones account for around 50% of all refuges,which means that more refuges should be built in the higher and highest risk zones to meet the accommodation requirement;(4) three methods proved to be feasible and effective in evaluating flood disaster risk,among which FCA is more suitable for the study area than the two other methods. | Weiguo Jiang Lei Deng Luyao Chen Jianjun Wu Jing Li | 2009 | Progress in Natural Science:Materials International2009，19，10： | 35 |
| 2 | Complication and safety of ultrasound guided percutaneous nephrolithotomy in 8 025 cases in China显示文摘 | Li Jianxing Xiao Bo Hu Weiguo Yang Bo Chen Liang Hu Hao Wang Xiaofeng | 2014 | Chinese Medical Journal2014，，24： | 36 |
| 3 | Quantifying driving forces of urban wetlands change in Beijing City显示文摘决定树和阀值方法被采用了描出从 LANDSAT 图象的水身体的边界和特征。在空间覆盖分析以后并且用在北京的一种遥感技术和沼泽地库存数据,水身体视觉上在 1986 在北京的城市的沼泽地上被分类进城市的沼泽地,和数据的不同类型, 1991 , 1996 , 2000 , 2002 , 2004 和 2007 被获得。影响沼泽地变化的 13 辆开车因素被选择,并且灰色的关联分析被采用计算在每个开车因素和城市的沼泽地的全部的区域之间的关联。然后,六个主要开车因素基于关联系数被选择,并且贡献这六个开车因素评价到各种各样的城市的沼泽地的区域变化基于正规关联分析被计算。在那以后,这研究分析了在主要开车因素和沼泽地的各种各样的类型之间的关系和机制。五个结论能被得出。(1 ) 在北京的表面水身体的全部的区域从 1986 ~ 1996 增加了,并且逐渐地从 1996 ~ 2007 减少了。(2 ) 河沼泽地,水存储区域和水池的区域和文化区域逐渐地减少了,并且它的变化趋势与沼泽地的全部的区域的一致。采矿水区域和废水处理植物的区域稍微增加了。( 3 )驱动力的六个因素是年度降雨,蒸发,流入水的数量,可得到的地下水的体积,都市化率和废水的每天平均的分泌物是在沼泽地区域影响变化的主要因素,并且他们与沼泽地的全部的区域相关很好。(4 ) 象流入水和地下水的体积的数量那样的水资源的 hydrologic 指示物是影响沼泽地区域的变化的最重要、直接的驱动力。这些因素有 43.94% 的联合贡献率。(5 ) 象降雨和蒸发那样的气候因素是在沼泽地区域影响变化的外部因素,并且他们有 36.54% 的贡献率。(6 ) 象都市化率和废水的每天平均的数量那样的人的活动是主要人工的开车因素。他们有 19.52% 的影响率。 | JIANG Weiguo WANG Wenjie CHEN Yunhao LIU Jing TANG Hong HOU Peng | 2012 | Journal of Geographical Sciences2012，22，2： | 25 |
| 4 | The response of vegetation growth to shifts in trend of temperature in China显示文摘尽管许多研究在温度的趋势集中了于移动的原因,到温度的植被生长的反应是否变化了,仍然不是很清楚的。在这研究,我们从 1984 ~ 2011 基于观察气候的数据和规范的差别植被索引(NDVI ) 在中国在成长季节和植被生长的反应期间分析了温度的趋势变化的空间特征。到在从时期 1984-1997 种季节到时期 1998-2011 期间使移动凉下来的明显的温暖在中国的北、东北的区域被识别,而一完全交谈移动在南部、西方的区域被观察,建议在整个中国种季节温度的趋势的变化的大空间异质。整个的中国,在植被生长和温度之间的一种重要积极关系极大地在 1998-2011 期间在 1984 ~ 1997 期间被削弱了。到温度的植被生长的反应的这个变化被 Granger 诱发性测试也证实了。在地区性的规模上,在在植被生长和温度之间的关系中的明显的移动在适度的荒芜的区域和雨林区域被识别。由包括地在 NDVI 和气候变量之间的关系分析,而且,植被生长上的气候因素的影响的全面减小在最近的年期间在中国上被识别,显示从人的联系活动的提高的影响。 | HE Bin CHEN Aifang JIANG Weiguo CHEN Ziyue | 2017 | Journal of Geographical Sciences2017，27，7： | 23 |
| 5 | Inter-annual variations in vegetation and their response to climatic factors in the upper catchments of the Yellow River from 2000 to 2010显示文摘在黄河的上面的集水在有气候因素的植被和他们的关联理解变化,中国,从 2000 ~ 2010 的规范的差别植被索引(NDVI ) 时间系列数据基于 MOD13Q1 产品被收集。变化, Theil 参议员中部的趋势分析和 Mann-Kendall 测试的系数被联合调查轻快特征和植被的趋势特征。气候数据集合然后被用来在植被和气候变化分析在变化之间的关联。以时间的变化,在这个学习区域的植被从 2000 ~ 2010 稍微改善了,尽管轻快特征比在 20062010 在 20002005 是更大的。以空间变化,相对稳定并且有一个显著地增加的趋势的植被说明学习区域的最大的部分。它的空间分发高度与高度被相关,它在这个区域从大约 2000 ~ 3000 m 。显示出一个显著地减少的趋势的高度波动的植被和植被主要与水力发出的电力开发在水库附近并且在河的活动范围被散布。有一个相对稳定、显著地减少的趋势的植被和有高度波动和显著地增加的趋势的植被广泛地被驱散。关于到气候变化的植被的反应,大约 2030% 植被与气候的因素有重要关联,在大多数区域的关联是积极的:有降水的区域作为关键影响因素占超过 10% 区域;有温度的区域作为关键影响因素占不到 10% 区域;并且有降水和温度的区域作为一起影响因素的钥匙占大约 5% 全部的区域。超过 70% 植被与气候的因素有不足道的关联。 | CAO Ran JIANG Weiguo YUAN Lihua WANG Wenjie LV Zhongliang CHEN Zheng | 2014 | Journal of Geographical Sciences2014，24，6： | 19 |
| 6 | 中医药治疗高血压作用机制的研究进展显示文摘高血压是一种以体循环动脉压升高为主要临床表现的疾病,其发病机制复杂。随着近年来中医药事业的发展,中医药治疗高血压不仅能够控制血压,在改善症状、提高患者生活质量等方面也起到良好作用。其作用机制主要有:(1)对肾素血管紧张素醛固酮系统(RAAS)的作用:中医药主要通过抑制肾素的作用、抑制血管紧张素转换酶的活性、拮抗血管紧张素Ⅱ(AngⅡ)受体3个关键点,下调心脏糜蛋白酶信号通路,下调AngⅡ1型受体(AT1R)的mRNA表达而控制血压水平;(2)抑制血管运动中枢和抑制交感神经或阻断神经节的作用,从而抑制交感神经活动;(3)内皮功能障碍是高血压发生发展的重要原因之一,保护血管内皮是防治高血压的关键。中医药能够通过磷脂酰肌醇3激酶(PI3K)/蛋白激酶B(Akt)/哺乳动物雷帕霉素靶蛋白(mTOR)/缺氧诱导因子(HIF)信号通路上调内皮型一氧化氮合酶(eNOS)的表达,增加Krüppel样因子4(KLF4)磷酸化促进内皮细胞增殖,从而改善血管内皮功能,具有减少血管内皮细胞黏附分子(CD54、CD62P)的表达,抑制白细胞和内皮细胞黏附及抑制血管壁炎症等作用;(4)中医药可以上调PI3Kp85mRNA和胰岛素受体底物1(IRS1)蛋白,从而改善胰岛素抵抗进而稳定血压;(5)中医药干预高血压与细胞膜离子通道的作用主要通过开放ATP敏感性钾通道(KATP)、内向整流钾通道(Kir)和电压门控钾通道(Kv)等诱导血管舒张功能、参与Ca^(2+)/一氧化氮/环磷酸鸟苷(cGMP)通路引起血管内皮舒张从而控制血压。 | Rongzhong Xu Weiguo Chen | 2017 | 中华高血压杂志2017，25，2： | 15 |
| 7 | Effects of Nogo-neutralizing antibody and neurotrophin-3 on axonal regeneration following spinal cord injury in rats显示文摘BACKGROUND: Recent studies have suggested that regeneration of the central nerve fiber following spinal cord injury occurs under specific conditions. OBJECTIVE: To study the effects of Nogo-neutralizing antibody (IN-1), in combination with neurotrophin-3 (NT-3), on axonal regeneration and motor function following spinal cord injury in the rat. DESIGN, TIME AND SETTING: A randomized, controlled, animal study combining immunohistochemistry was performed at the Laboratory of Neuroanatomy of Xiangya Medical College, and Central Laboratory of Xiangya the Third Hospital, Central South University from January 2006 to December 2007. MATERIALS: Eighteen healthy, Sprague Dawley rats were randomly divided into three groups, with six rats per group: control, IN-1, and IN-1/NT-3. Hemisectioned spinal cord injury models were established by cutting the posterior 2/3 of spinal cord, which is equivalent to the T8 level. METHODS: A polyethylene tubing was inserted through into subarachnoid cavity, equivalent to the superior margin at the T8 level. Saline, IN-1, and IN-1/NT-3 were respectively injected into control, IN-1, and IN-1/NT-3 groups, three times/day for seven consecutive days. MAIN OUTCOME MEASURES: At 2 weeks post-surgery, biotin dextran amine (10%) was injected into the right sensorimotor cortex area. At day 28 post-surgery, spinal cord tissue was prepared for frozen sections. Positive astrocytic expression was observed with glial fibrillary acidic protein (GFAP) immunohistochemical staining whose proliferation level was represented by gray value, i.e. the higher the gray value was, the less the positive cells were, and growth of positive fibers was observed with a biotin dextran amine histological reaction. Motor function was measured according to BBB scores pre-operatively, as well as at days 1, 7, 14, 21, and 28 post-operatively. RESULTS: Three rats died during experimentation. By random supplement, a total of 18 rats were included. GFAP-positive astrocytes were observed in all the three groups. In the control group, astrocytes were characterized according to active function, hyperplasia, proliferation, hypertrophy, and increasing processes as compared to IN-1 group and IN-1/IN-3 group. Astrocyte hyperplasia represented by gray value in the IN-1 group was less than the control group. Gray value of GFAP-positive products in the IN-1/IN-3 group was higher than other two groups (P < 0.05). Biotin dextran amine tracing demonstrated no corticospinal tract fiber outgrowth following spinal cord injury; the fibers were incapable of passing through the glial scar in the control group. Several fibers were distributed in the proximal scar tissue region in the IN-1 group, and the regenerated fibers were disarranged. Many nerve fibers were distributed throughout the scar tissue, and even several biotin dextran amine-positive fibers were observed at the distal end of the injured segment. Post-operative Basso, Beattie, Bresnahan scores were greater than pre-operative ones, while Basso, Beattie, Bresnahan scores in the IN-1/NT-3 group were significantly greater than the other two groups at days 14, 21, and 28 post-surgery (P < 0.05). CONCLUSION: IN-1, in combination with NT-3, promoted axonal regeneration following spinal cord injury, inhibited the colloidal effect, and enhanced the correlation between proximal and distal processes to recover motor function. The recovery effect of IN-1/NT-3 on motor function was superior that of to IN-1 alone. | Ruisen Zhan Shijie Chen Weiguo Wang Haibin Long | 2008 | Neural Regeneration Research2008，3，12： | 10 |
| 8 | Longitudinal non-vascular transport pathways originating from acupuncture points in extremities visualised in human body显示文摘A subcutaneous transport pathway in humans has been previously visualised by injection of a paramagnetic tracer into the specific region of skin.In the current study,we further investigated the behaviours of imaging tracers in the transport pathways using imaging techniques.Three types of imaging tracers,including Gd-DTPA,iodised oil,and fluorescein sodium,were hypodermically injected into different acupuncture points of healthy volunteers to visualise the transport pathways by magnetic resonance imaging(MRI),X-ray,CT,and a digital fluorescein camera.Several longitudinal transport pathways in the arms and feet,which represent venous vessels and subcutaneous transport pathways(STPs) without well-defined boundaries,were visualised by MRI.Among the visualised veins,the partial walls of a few veins were enhanced by Gd-DTPA.The fluorescent images further indicated that STPs likely represent boundless pathways.The findings in this study suggested that specific anatomical structures within the subcutaneous tissues or the partial walls of certain veins werenot vascular conduits but rather represented unique transport pathways in humans that warrant extensive future studies. | Hongyi Li Jiabin Tong Weiguo Cao Min Chen Hua Li Hong Dai Liang Xu Xiaoliang Chen | 2014 | Chinese Science Bulletin2014，59，35： | 10 |
| 9 | Branched tetraether lipids in Chinese soils:Evaluating the fidelity of MBT/CBT proxies as paleoenvironmental proxies显示文摘The ubiquitous occurrence of branched glycerol dialkyl glycerol tetraethers(br GDGTs) in soils has allowed development of new proxies for reconstruction of past climate and environment. The methylation and cyclization degrees of br GDGTs, expressed as MBT and CBT, respectively, are reported to be mainly controlled by mean annual air temperature(MAAT) and soil p H. However, the br GDGT-derived temperatures and soil p H scatter widely when data from different environmental conditions are considered. In this study, we collected over 300 soil samples from China, which are representative of humid(Xishuangbanna, Guangzhou, and Shanghai), semi-arid(Dongying) and semi-arid/arid(Lanzhou, Tibetan Plateau) regions. Collectively we have the most extensive dataset that broadly characterizes the distribution of br GDGTs according to climate zones in China. The overall data demonstrate that the MBT/CBT derived temperatures better match the measured MAATs in humid and non-alkaline regions than those from regions of low MAP(<400 mm/yr) and above neutral soil p H(>7.0–7.5). Similarly, CBT describes soil p H much better in humid and non-alkaline soils than in semi-arid/arid and alkaline soils; the semi-arid/arid and alkaline soils tend to show a positive correlation between soil p H and CBT, which contradicts that in the humid and non-alkaline soils. While soil p H, MAAT and mean annual precipitation(MAP) are dominating factors controlling the br GDGT distribution across all climate zones, conductivity, total organic carbon and total nitrogen, as well as soil water content can also play an important role locally. Removing br GDGT-II resulted in a revised CBT index that provides more accurate estimation of p H, especially in semi-arid/arid and alkaline soils. The overall Chinese dataset demonstrates that continental air temperature derived from br GDGT-proxies can vastly deviate from real measurements and should be used with extreme caution in paleo-climate or-environment studies. | ZHENG FengFeng ZHANG ChuanLun CHEN YuFei LI FuYan MA CenLing PU Yang ZHU YuanQing WANG YongLi LIU WeiGuo | 2016 | Science China Earth Sciences2016，59，7： | 10 |
| 10 | Economic Value Evaluation of Wetland Service in Yeyahu Wetland Nature Reserve,Beijing显示文摘Based on multi-source data,this paper evaluated the economic value of ecological services in the Yeyahu Wetland Nature Reserve,Beijing,China.The ecological services of wetland included gas regulation,water quality im-provement,biodiversity maintenance,erosion control,water supply,recreational opportunity,raw material supply and existence value.Multiple conventional evaluation methods were used to calculate the value of eight wetland services.The results showed that significant values came from biodiversity maintenance and recreational opportunity.The main reasons were as follows.Firstly,Yeyahu Wetland Nature Reserve was the habitat for migrant birds,and government had payed more efforts to protect precious birds.Secondly,the population is large in Beijing.People enjoyed going outside and enjoyed the natural and artificial wetland scenes.At the same time,most people were prepared to pay for wetland conservation.The decline of vegetation cover made the economic value of erosion control the lowest.While the shrink of water resource and the deteriorative water quality caused the economic value of water supply lower.The evaluation results could help decision-makers understand the present status of the Yeyahu Wetland Nature Reserve and provide a scientific basis for strategic decision. | ZHU Lin CHEN Yun GONG Huili JIANG Weiguo ZHAO Wenji XIAO Yanfang | 2011 | Chinese Geographical Science2011，21，6： | 7 |
| 11 | Relay-intercropping soybean with maize maintains soil fertility and increases nitrogen recovery efficiency by reducing nitrogen input显示文摘Optimized nitrogen(N)management can increase N-use efficiency in intercropping systems.Legume-nonlegume intercropping systems can reduce N input by exploiting biological N fixation by legumes.Measurement of N utilization can help in dissecting the mechanisms underlying N uptake and utilization in legume-nonlegume intercropping systems.An experiment was performed with three planting patterns:monoculture maize(MM),monoculture soybean(SS),and maize-soybean relay intercropping(IMS),and three N application levels:zero N(NN),reduced N(RN),and conventional N(CN)to investigate crop N uptake and utilization characteristics.N recovery efficiency and 15N recovery rate of crops were higher under RN than under CN,and those under RN were higher under intercropping than under the corresponding monocultures.Compared with MM,IMS showed a lower soil N-dependent rate(SNDR)in 2012.However,the SNDR of MM rapidly declined from 86.8%in 2012 to 49.4%in 2014,whereas that of IMS declined slowly from 75.4%in 2012 to 69.4%in 2014.The interspecific N competition rate(NCRms)was higher under RN than under CN,and increased yearly.Soybean nodule dry weight and nitrogenase activities were respectively 34.2%and 12.5%higher under intercropping than in monoculture at the beginning seed stage.The amount(Ndfa)and ratio(%Ndfa)of soybean N2 fixation were significantly greater under IS than under SS.In conclusion,N fertilizer was more efficiently used under RN than under CN;in particular,the relay intercropping system promoted N fertilizer utilization in comparison with the corresponding monocultures.An intercropping system helps to maintain soil fertility because interspecific N competition promotes biological N fixation by soybean by reducing N input.Thus,a maize-soybean relay intercropping system with reduced N application is sustainable and environmentally friendly. | Qing Du Li Zhou Ping Chen Xiaoming Liu Chun Song Feng Yang Xiaochun Wang Weiguo Liu Xin Sun Junbo Du Jiang Liu Kai Shu Wenyu Yang Taiwen Yong | 2020 | The Crop Journal2020，8，1： | 7 |
| 12 | Microbial diversity accumulates in a downstream direction in the Three Gorges Reservoir显示文摘Organic and inorganic materials migrate downstream and have important roles in regulating environmental health in the river networks.However,it remains unclear whether and how a mixture of materials(i.e.,microbial species)from various upstream habitats contribute to microbial community coalescence upstream of a dam.Here we track the spatial variation in microbial abundance and diversity in the Three Gorges Reservoir based on quantitative PCR and 16 S rRNA gene high-throughput sequencing data.We further quantitatively assess the relative contributions of microbial species from mainstem,its tributaries,and the surrounding riverbank soils to the area immediately upstream of the Three Gorges Dam(TGD).We found an increase of microbial diversity and the convergent microbial distribution pattern in areas immediately upstream of TGD,suggesting this area become a new confluence for microbial diversity immigrating from upstream.Indeed,the number of shared species increased from upstream to TGD but unique species decreased,indicating immigration of various sources of microbial species overwhelms local environmental conditions in structuring microbial community close to TGD.By quantifying the sources of microbial species close to TGD,we found little contribution from soils as compared to tributaries,especially for sites closer to TGD,suggesting tributary microbes have greater influence on microbial diversity and environmental health in the Three Gorges Reservoir.Collectively,our results suggest that tracking microbial geographic origin and evaluating accumulating effects of microbial diversity shed light on the ecological processes in microbial communities and provide information for regulating aquatic ecological health. | Shang Wang Weiguo Hou Hongchen Jiang Liuqin Huang Hailiang Dong Shu Chen Bin Wang Yongcan Chen Binliang Lin Ye Deng | 2021 | Journal of Environmental Sciences2021，33，3： | 7 |
| 13 | Synergistically Enhanced Mucoadhesive and Penetrable Polypeptide Nanogel for Efficient Drug Delivery to Orthotopic Bladder Cancer显示文摘Intravesical chemotherapy has been recommended after the gold standard of transurethral resection of the bladder tumor to prevent bladder cancer(BC)from local recurrence in the clinic.However,due to rapid urine excretion and barrier protection of the bladder wall,the clinical performances of chemotherapeutic drugs are severely compromised.In the present work,a smart positively charged disulfide-crosslinked nanogel of oligoarginine-poly(ethylene glycol)-poly(L-phenylalanine-co-L-cystine)(R_(9)-PEG-P(LP-co-LC))was prepared to prolong the retention period and enhance the penetration capability of chemotherapeutic agent toward the bladder wall.PEG significantly improved the aqueous dispersibility of the 10-hydroxycamptothecin(HCPT)-loaded R_(9)-PEG-P(LP-co-LC)(i.e.,R_(9)NG/HCPT)and enhanced the mucoadhesive capability by the nonspecific interaction between PEG chain and the bladder mucosa accompanied with the electrostatic interaction between the cationic R_(9)and negatively charged bladder mucosa.Besides,R_(9),as a cell-penetrating peptide,efficiently penetrated through the cell membrane and delivered carried cargo.The disulfide bond endowed the selective release behavior of HCPT triggered by the intracellular reductive microenvironment.As an advanced chemotherapeutic nanoformulation,the smart R_(9)NG/HCPT demonstrated superior cytotoxicity against human BC 5637 cells in vitro and remarkably enhanced tumor suppression activity toward orthotopic BC models of mouse and rat in vivo,indicating its great potential in the clinical intravesical BC chemotherapy. | Hui Guo Faping Li Heping Qiu Weiguo Xu Pengqiang Li Yuchuan Hou Jianxun Ding Xuesi Chen | 2020 | Research2020，，1： | 7 |
| 14 | African Swine Fever Virus Protein E199L Promotes Cell Autophagy through the Interaction of PYCR2显示文摘African swine fever virus(ASFV),as a member of the large DNA viruses,may regulate autophagy and apoptosis by inhibiting programmed cell death.However,the function of ASFV proteins has not been fully elucidated,especially the role of autophagy in ASFV infection.One of three Pyrroline-5-carboxylate reductases(PYCR),is primarily involved in conversion of glutamate to proline.Previous studies have shown that depletion of PYCR2 was related to the induction of autophagy.In the present study,we found for the first time that ASFV E199 L protein induced a complete autophagy process in Vero and HEK-293 T cells.Through co-immunoprecipitation coupled with mass spectrometry(Co IP-MS)analysis,we firstly identified that E199 L interact with PYCR2 in vitro.Importantly,our work provides evidence that E199 L down-regulated the expression of PYCR2,resulting in autophagy activation.Overall,our results demonstrate that ASFV E199 L protein induces complete autophagy through interaction with PYCR2 and down-regulate the expression level of PYCR2,which provide a valuable reference for the role of autophagy during ASFV infection and contribute to the functional clues of PYCR2. | Sheng Chen Xinheng Zhang Yu Nie Hongxin Li Weiguo Chen Wencheng Lin Feng Chen Qingmei Xie | 2021 | Virologica Sinica2021，36，2： | 7 |
| 15 | Multistring analysis of wellhead movement and uncemented casing strength in offshore oil and gas wells显示文摘This paper presents a theoretical method and a finite element method to describe wellhead movement and uncemented casing strength in offshore oil and gas wells. Parameters considered in the theoretical method include operating load during drilling and completion and the temperature field, pressure field and the end effect of pressure during gas production. The finite element method for multistring analysis is developed to simulate random contact between casings. The relevant finite element analysis scheme is also presented according to the actual procedures of drilling, completion and gas production. Finally, field cases are presented and analyzed using the proposed methods. These are four offshore wells in the South China Sea. The calculated wellhead growths during gas production are compared with measured values. The results show that the wellhead subsides during drilling and completion and grows up during gas production. The theoretical and finite element solutions for wellhead growth are in good agreement with measured values and the deviations of calculation are within 10%. The maximum von Mises stress on the uncemented intermediate casing occurs during the running of the oil tube. The maximum von Mises stress on the uncemented production casing, calculated with the theoretical method occurs at removing the blow-out-preventer(BOP) while that calculated with the finite element method occurs at gas production. Finite element solutions for von Mises stress are recommended and the uncemented casings of four wells satisfy strength requirements. | Liu Xiuquan Chen Guoming Chang Yuanjiang Zhang Lei Zhang Weiguo Xie Hua | 2014 | Petroleum Science2014，11，1： | 7 |
| 16 | Response of winter cohort abundance of Japanese common squid Todarodes pacificus to the ENSO events显示文摘The Japanese common squid Todarodes pacificus is an economically important species with one year lifespan,which is significantly influenced by climatic and environmental variability. According to the fishery data of the winter cohort of T. pacificus from 2003 to 2012, as well as environmental data and the Oceanic Ni?o index(ONI,which was defined by the sea surface temperature(SST) anomaly in the Ni?o 3.4 region), variations in the SST,chlorophyll a(Chl a) concentration, suitable spawning area(SSA) and sea surface height anomaly(SSHA) on the spawning ground of T. pacificus were examined under the El Ni?o and La Ni?a conditions. Their influences on squid abundance(defined by catch per unit effort, CPUE) were further assessed. The results showed that seasonal changes were found in SST, Chl a and SSA on the spawning ground of T. pacificus. Correlation analysis suggested that annual CPUE was significantly positively correlated with Chl a and SSA(p<0.05), but had insignificant relationship with SST(p>0.05). Moreover, the El Ni?o and La Ni?a events tended to dominate the changes of SSA and Chl a concentration in the key area between 25°–29°N and 122.5°–130.5°E, driving the variability of squid abundance. However, this influence varied with the intensity of each anomalous climatic event: the weak El Ni?o event occurred, the spawning ground was occupied by waters with enlarged SSA but with extremely low Chl a concentration, leading to low squid recruitment, the CPUE then decreased; the moderate intensity of El Ni?o event resulted in shrunk SSA but with high Chl a concentration on the spawning ground, the squid recruitment and CPUE increased; the moderate intensity of La Ni?a events yielded elevated SSA and high Chl a concentration on the spawning ground, the squid recruitment and CPUE dramatically increased. Our findings suggested that the ENSO events played crucial effects on the incubating and feeding conditions of the winter cohort of T. pacificus during the spawning season and ultimately affected its abundance. | YU Wei ZHANG Yang CHEN Xinjun YI Qian QIAN Weiguo | 2018 | Acta Oceanologica Sinica2018，37，6： | 7 |
| 17 | Endothelial activation and dysfunction in COVID-19:from basic mechanisms to potential therapeutic approaches显示文摘On 12 March 2020,the outbreak of coronavirus disease 2019(COVID-19)was declared a pandemic by the World Health Organization.As of 4 August 2020,more than 18 million confirmed infections had been reported globally.Most patients have mild symptoms,but some patients develop respiratory failure which is the leading cause of death among COVID-19 patients.Endothelial cells with high levels of angiotensin-converting enzyme 2 expression are major participants and regulators of inflammatory reactions and coagulation.Accumulating evidence suggests that endothelial activation and dysfunction participate in COVID-19 pathogenesis by altering the integrity of vessel barrier,promoting pro-coagulative state,inducing endothelial inflammation,and even mediating leukocyte infiltration.This review describes the proposed cellular and molecular mechanisms of endothelial activation and dysfunction during COVID-19 emphasizing the principal mediators and therapeutic implications. | Yuefei Jin Wangquan Ji Haiyan Yang Shuaiyin Chen Weiguo Zhang Guangcai Duan | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 6 |
| 18 | A new distinct geminivirus causes soybean stay-green disease显示文摘Dear Editor,Plant viruses make up almost half of the plant disease-causing pathogens,affecting crop yields and the global economy(Savary et al.,2019).Soybean(Glycine max)is one of the most valuable legume crops in the world,supplying 25%of the global edible oil and two-thirds of the global concentrated protein for livestock feeding.Recently,the outbreak of soybean stay-green syndrome with delayed leaf senescence(stay-green),flat pods,and increased number of abnormal seeds has swept the soybean production in the Huang-Huai-Hai region of China,resulting in huge yield losses(Xu et al.,2019).This disease has become an epidemic and prominent problem in soybean production and is still expanding its geography,including North America,posing a serious threat to soybean production(Harbach et al.,2016;Zhang et al.,2016;Li et al.,2019).However,the cause of soybean stay-green syndrome remains obscure. | Ruixiang Cheng Ruoxin Mei Rong Yan Hongyu Chen Dan Miao Lina Cai Jiayi Fan Gairu Li Ran Xu Weiguo Lu Yu Gao Wenwu Ye Shuo Su Tianfu Han Junyi Gai Yuanchao Wang Xiaorong Tao Yi Xu | 2022 | Molecular Plant2022，15，6： | 6 |
| 19 | Recurrence Characteristics of Major Earthquakes in the Tangshan area,North China显示文摘Tangshan 区域躺在一位女士 7.8 地震发生在 1976 的北方中国平原,它与一个隐藏的活跃差错被联系。为了揭示专业的复发特征,在一相对长的时间在这个区域震动,我们用地质的调查,浅地震探索,地上凿穿,沟观察并且地质的标明日期进行了全面研究。五 paleoearthquakes 向西在一条 6.4m-deep 沟被认出到 Tangshan 精神病院。在他们之中,前者三个事件发生在 56.78 敮之间? | LIU Kang QU Guosheng CHEN Jianqiang WANG Weiguo NING Baokun | 2013 | Acta Geologica Sinica(English Edition)2013，87，1： | 5 |
| 20 | Magnetic evidence for heavy metal pollution of topsoil in Shanghai, China显示文摘这研究介绍从土壤侧面的集中大小在 Baoshan 区域从可耕地和城市的公园收集了的磁性的危险性和重金属(Cu, Zn, Pb,和 Cr ) 获得的结果,上海的一个工业区域,中国。学习在土壤侧面在磁性的危险性和重金属集中并且在在磁性的危险性和重金属集中之间的关联上集中于垂直变化的调查。结果证明在土壤侧面的表面层的那磁性的改进与增加的重金属污染被联系。丰富因素(EF ) 和 Tomlinson 污染负担索引(PLI-EF ) 为在学习估计土壤侧面的重金属污染的水平被计算。在重金属内容,丰富因素(EF ) , Tomlinson 污染负担索引(PLI-CF ) ,修改 Tomlinson 污染负担索引(PLI-EF ) ,和磁性的危险性(c) 之间的重要积极关联重金属那么显示在学习区域的污染被连接到燃烧导出的微粒排出物。结果证实联合磁性的测量和重金属集中分析能为在城市的环境监视的土壤提供有用信息。然而,磁性的技术的使用应该被进一步的 geochemical 分析证实在这个学习区域的土壤侧面定位重金属污染边界。 | Guan WANG Yuan LIU Jiao CHEN Feifan REN Yuying CHEN Fangzhou YE Weiguo ZHANG | 2018 | Frontiers of Earth Science2018，12，1： | 5 |
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