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| 1 | Alkali metal salts doped pluronic block polymers as electron injection/transport layers for high performance polymer light-emitting diodes显示文摘A series of alkali metal salts doped pluronic block copolymer F127 were used as electron injection/transport layers (ETLs) for polymer light-emitting diodes with poly[2-(4-(3′,7′-dimethyloctyloxy)-phenyl)-p-phenylenevinylene] (P-PPV) as the emission layer. It was found that the electron transport capability of F127 can be effectively enhanced by doping with alkali metal salts. By using Li2CO3 (15%) doped F127 as ETL, the resulting device exhibited improved performance with a maximum luminous efficiency (LE) of 13.59 cd/A and a maximum brightness of 5529 cd/m2, while the device with undoped F127 as ETL only showed a maximum LE of 8.78 cd/A and a maximum brightness of 2952 cd/m2. The effects of the doping concentration, cations and anions of the alkali metal salts on the performance of the resulting devices were investigated. It was found that most of the alkali metal salt dopants can dramatically enhance the electron transport capability of F127 ETL and the performance of the resulting devices was greatly improved. | ZHANG Kai LIU ShengJian GUAN Xing DUAN ChunHui ZHANG Jie ZHONG ChengMei WANG Lei HUANG Fei CAO Yong | 2012 | Science China Chemistry2012，55，5： | 5 |
| 2 | Dendrocalamus latiflorus and its component rutin exhibit glucose-lowering activities by inhibiting hepatic glucose production via AKT activation显示文摘The potential medicinal value of Ma bamboo(Dendrocalamus latiflorus), one of the most popular and economically important bamboo species in China, has been underestimated. In the present study, we found that D. latiflorus leaf extract(DLE) reduced fasting blood glucose levels, body weight,and low-density lipoprotein cholesterol with low liver toxicity in db/db mice. In addition, gene expression profiling was performed and pathway enrichment analysis showed that DLE affected metabolic pathways.Importantly, DLE activated the AKT signaling pathway and reduced glucose production by downregulating glucose-6-phosphatase(G6 PC) and phosphoenolpyruvate carboxykinase 1(PCK1) expression. Moreover, network pharmacology analysis identified rutin as an active component in DLE through targeting insulin growth factor 1 receptor(IGF1 R), an upstream signaling transducer of AKT. Due to its hypoglycemic effects and low toxicity, DLE may be considered an adjuvant treatment option for type 2 diabetes patients. | Kun Luo Wenting Huang Liansheng Qiao Xiaoling Zhang Di Yan Zhiyu Ning Chengmei Ma Honglei Dang Dong Wang Hongyan Guo Lan Xie Jing Cheng | 2022 | Acta Pharmaceutica Sinica B2022，12，5： | 4 |
| 3 | A novel crosslinkable electron injection/transporting material for solution processed polymer light-emitting diodes显示文摘A novel crosslinkable water/alcohol soluble conjugated polymer PFN-C containing oxetane groups and aminoalkyl groups in the side chains has been developed and used as highly efficient electron injection and transporting material for polymer light-emitting diodes (PLEDs). The unique solubility in polar solvents and crosslinkable ability of PFN-C render it a good can- didate for solution processed multilayer PLEDs. It was found that PFN-C can greatly enhance the electron injection from high work-function metal cathode, due to its pendant amino groups. As a result, PLEDs with PFN-C/Al cathode exhibited compara- ble device performance to the devices with Ba/Al cathode. The resulting green light-emitting device showed promising perfor- mance with a maximum luminance efficiency of 13.53 cd A-1. | LIU ShengJian ZHONG ChengMei ZHANG Jie DUAN ChunHui WANG XiaoHui HUANG Fei | 2011 | Science China Chemistry2011，54，11： | 4 |
| 4 | Study on Pretreatment during Simultaneous Determination of Sulfonamides and Chloramphenicols in Honey显示文摘[Objective]This study was conducted to establish a new UPLC-MS method for simultaneous detection of sulfonamides and chloramphenicols in honey.[Method]In this experiment,0.2%formic acid-acetonitrile was used as an extractant to simultaneously extract chloramphenicols and sulfonamides from drugs.The extract was then loaded and extracted with an efficient separation column Oasis~?PRiME HLB.After nitrogen blow-concentration and dissolution with mobile phase,the extract was loaded on UPLC and detected by MS.[Result]There was a good linear relation in the range of 0.1-10ng/ml for chloramphenicols,with a correlation coefficient of 0.991,while sulfonamides had a good linear relation in the range of 0.5-50ng/ml.The lowest detection limit of chloramphenicols and sulfonamides were 0.1and 0.5μg/kg,respectively.The recoveries were in the range of 82.50%-101.2%,with RSDvalues in the range of 3.2%-4.0%.[Conclusion]This method is simple and fast with low detection limit,high recovery and good reproducibility,and could be used for simultaneous detection of residual chloramphenicols and sulfonamides in honey. | Guangfeng ZHONG Xiaoling LIU Chengmei WANG | 2017 | Agricultural Biotechnology2017，6，2： | 2 |
| 5 | Characterization of coal burning-derived individual particles emitted from an experimental domestic stove显示文摘Coal combustion in the domestic stoves, which is common in most parts of the Chinese countryside, can release harmful substances into the air and cause health issues. In this study, particles emitted from laboratory stove combustion of the raw powder coals were analyzed for morphologies and chemical compositions by using transmission electron microscopy(TEM) coupled with energy-dispersive X-ray spectrometry(EDX). The coal burning-derived individual particles were classified into two groups: carbonaceous particles(including soot aggregates and organic particles) and non-carbonaceous particles(including sulfate, mineral and metal particles). The non-carbonaceous particles, which constituted a majority of the coal burning-derived emissions, were subdivided into Si-rich, S-rich, K-rich,Ca-rich, and Fe-rich particles according to the elemental compositions. The Si-rich, S-rich and K-rich particles are commonly observed in the coal burning emission. The proportions for particles of different types exhibit obvious coal-issue dependence. Burning of coal with high ash yield could emit more non-carbonaceous particles, and burning of coal with high sulfur content can emit more S-rich particles. By comparing the S-rich particles from this coal burning experiment with those in the atmosphere, we draw a conclusion that some S-rich particles in the atmosphere in China could be mainly sourced from coal combustion. | Cong Hou Longyi Shao Chengmei Zhao ling Wang Junxia Liu Chunmei Geng | 2018 | Journal of Environmental Sciences2018，30，9： | 2 |
| 6 | Uncertainty Analysis of Residues of Nitrofuran Metabolites in Chicken Bone显示文摘[Objectives] Uncertainty in liquid chromatography-mass spectrometry detection of nitrofuran metabolite residues in chicken bone was analyzed to find out the influencing factors. [Methods] According to relevant theories such as Evaluation and expression of uncertainty in measurement,the uncertainty in the results of nitrofuran metabolites in chicken bone was analyzed and calculated combining with mathematical models. [Results] Under the addition amount of 1. 0 μg/kg,the uncertainty of the four nitrofuran metabolites was as follows: nitrofurazone metabolites C(SEM)= 0. 981 μg/kg,U = 0. 070 μg/kg,k = 2;furazolidone metabolites C(AOZ)= 1. 032 μg/kg,U = 0. 061 μg/kg,k = 2;furaltadone metabolites C(AMOZ)= 1. 068 μg/kg,U = 0. 076 μg/kg,k = 2;furadantin metabolites C(AHD)=1. 007 μg/kg,U = 0. 046 μg/kg,k = 2. [Conclusions]The uncertainty in the measurement process mainly comes from the purity of the standards,the preparation process,the sample weight,the number of repeated measurement and the recovery of spiked sample. The research results are of great significance for reducing uncertainty and improving data accuracy and reliability during actual operation. | Xiaolin ZHANG Chengmei WANG | 2020 | Agricultural Biotechnology2020，9，3： | 1 |
| 7 | Impact of adverse childhood experiences on the symptom severity of different mental disorders: a cross-diagnostic study显示文摘Background Adverse childhood experiences have a significant impact on different mental disorders.Objective To compare differences in adverse childhood experiences among those with different mental disorders and their relationships in a cross-disorder manner.Methods The study included 1513 individuals aged≥18 years:339 patients with substance use disorders,125 patients with schizophrenia,342 patients with depression,136 patients with bipolar disorder,431 patients with obsessive-compulsive disorder(OCD),and 140 healthy controls.The Early Trauma Inventory Self Report-Short Form was used to investigate childhood traumatic experiences,and the Addiction Severity Index,Positive and Negative Syndrome Scale,Hamilton Depression Scale,Young Mania Rating Scale,and Yale-Brown Obsessive-Compulsive Scale were used to assess mental disorder severity.Correlation and multivariate logistic regression were analysed between adverse childhood experiences and clinical features.Results Levels of adverse childhood experiences were significantly different among different mental disorders.Moreover,25.8%of patients with substance use disorders reported childhood trauma,which was significantly higher than found in the other four psychiatric disorder groups.Emotional abuse scores were positively correlated with disease severity:the higher the total trauma score,the more severe the mental disorder.Conclusions Adverse childhood experiences are a common phenomenon in those with mental disorders,and the level of trauma affects mental disorder severity.Emotional abuse is closely related to many mental disorders.The incidence or severity of mental disorders can be reduced in the future by reducing the incidence of adverse childhood experiences or by timely intervention in childhood trauma. | Wenjie Gu Qing Zhao Chengmei Yuan Zhenghui Yi Min Zhao Zhen Wang | 2022 | General Psychiatry2022，35，2： | 1 |
| 8 | Hybrid SVPWM strategy for diode-clamped 5H - bridge inverter 显示文摘 | LIN Chengmei WANG Gongbao LI Weichao | 2014 | ICEMS2014，2014，： | 1 |
| 9 | Important clinical features of atypical antipsychotics in acute bipolar depression that inform routine clinical care: a review of pivotal studies with number needed to treat显示文摘English-language literature cited in MEDLINE from January,1980 to October 30,2014 was searched by using terms of antipsychotic,generic and brand names of atypical antipsychotics, 'bipolar depression/bipolar disorder', 'placebo',and 'trial'.The parameters of response(≥50%improvement on MADRS,Montgomery-Asberg Depression Rating Scale total score),remission(either ≤12 or 8 on MADRS total score at endpoint),discontinuation due to adverse events(DAEs),somnolence,≥7%weight gain,overall extrapyramidal side-effects(EPSs),and akathisia,were extracted from originally published primary outcome papers.The number needed to treat to benefit(NNT) for response and remission or harm(NNH) for DAEs or other side effects relative to placebo were estimated and presented with the estimate and 95%confidence interval.Olanzapine monotherapy,olanzapine-fluoxetine combination(OFC),quetiapine-IR monotherapy,quetiapine-XR monotherapy,lurasidone monotherapy,and lurasidone adjunctive therapy were superior to placebo with NNTs for responses of 11-12,4,7-8,4,4-5,and 7,and NNTs for remission of 11-12,4,5-11,7,6-7,and 6,respectively.There was no significant difference between OFC and lamotrigine,and between aripiprazole or ziprasidone and placebo in response and remission.Olanzapine monotherapy,quetiapine-IR,quetiapine-XR,aripiprazole,and ziprasidone 120-160 mg/day had significantly increased risk for DAEs with NNHs of 24,8-14,9,12,and 10,respectively.For somnolence,quetiapine-XR had the smallest NNH of 4.For ≥7%weight gain,olanzapine monotherapy and OFC had the smallest NNHs with both of 5.For akathisia,aripiprazole had the smallest NNH of 5.These findings suggest that among the FDA-approved agents including OFC,quetiapine-IR and-XR,lurasidone monotherapy and adjunctive therapy to a mood stabilizer,the differences in the NNTs for response and remission are small,but the differences in NNHs for DAEs and common side-effects are large.Therefore,the selection of an FDA-approved atypical antipsychotic for bipolar depression should be based upon safety and tolerability. | Keming Gao Chengmei Yuan Renrong Wu Jun Chen Zuowei Wang Yiru Fang Joseph R.Calabrese | 2015 | Neuroscience Bulletin2015，31，5： | 1 |
| 10 | Determination of Sodium Pentachlorophenoxide Residues in Animal-derived Foods by Ultra-performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS)显示文摘[Objectives]This study was conducted to establish an ultra-high performance liquid chromatography-tandem mass spectrometry for the rapid extraction of sodium pentachlorophenoxide from animal-derived food.[Methods]The samples were extracted with an acetonitrile water solution(8∶2),0.1 mol/L hydrochloric acid and a purification extraction bag with shaking.Centrifugation was performed to obtain supernatants,which were added to purification tubes containing PSA and C_(18) for purification,and then filtered with membranes for determination.Each test solution was separated by a ZORBAX Eclipse plus C_(18) column with acetonitrile and 5 mmol/L ammonium acetate as mobile phases,and determined with electrospray ionization and multiple reaction monitoring.[Results]The method had good linearity in the concentration range of 1.0-50 ng/ml,and the correlation coefficient was 0.9997.The limit of detection was 0.25μg/kg and the limit of quantification was 0.75μg/kg.The recovery was between 87.4%and 112.5%,and the RSD%was between 0.5%and 10.0%.[Conclusions]The method has simple operation and high sensitivity,and is suitable for trace detection of sodium pentachlorophenoxide in large quantities of animal-derived food. | Chengmei WANG Chunxia CHENG Guixia YANG Susu ZHANG Xuan QIAN | 2022 | Agricultural Biotechnology2022，11，2： | 0 |
| 11 | Decoy Nanozymes Enable Multitarget Blockade of Proinflammatory Cascades for the Treatment of Multi-Drug- Resistant Bacterial Sepsis显示文摘Sepsis is a life-threatening organ dysfunction characterized by severe systemic inflammatory response to infection.Effective treatment of bacterial sepsis remains a paramount clinical challenge,due to its astonishingly rapid progression and the prevalence of bacterial drug resistance. | Xuancheng Du Mingzhen Zhang Huiting Zhou Weijie Wang Chengmei Zhang Lei Zhang Yuanyuan Qu Weifeng Li Xiangdong Liu Mingwen Zhao Kangsheng Tu Yong-Qiang Li | 2023 | Research2023，，2： | 0 |
| 12 | Study on the Quality Evaluation of Steamed Bread and the Physical and Chemical Properties of Wheat显示文摘In this study,the different physical and chemical properties of wheat were studied,and on this basis,and the quality of steamed bread made was evaluated.We analyzed the correlation between the evaluation indexes of steamed bread and the basic physical and chemical indexes of wheat,and investigated important factors that affect the evaluation indexes of steamed bread,including flour extraction rate,protein content,amylose content,protein,added amount of yeast,fermentation time and other aspects.According to the study results,it was shown that different factors had different effect on steamed bread quality,with both positive correlation and negative correlation. | Fenglan ZHANG Chengmei WANG De LI | 2021 | Agricultural Biotechnology2021，10，2： | 0 |
| 13 | Genome-wide association study of seedling nitrogen-use efficiency-associated traits in common wheat(Triticum aestivum L.)显示文摘Nitrogen(N)fertilizer application is essential for crop-plant growth and development.Identifying genetic loci associated with N-use efficiency(NUE)could increase wheat yields and reduce environmental pollution caused by overfertilization.We subjected a panel of 389 wheat accessions to N and chlorate(a nitrate analog)treatments to identify quantitative trait loci(QTL)controlling NUE-associated traits at the wheat seedling stage.Genotyping the panel with a 660K single-nucleotide polymorphism(SNP)array,we identified 397 SNPs associated with N-sensitivity index and chlorate inhibition rate.These SNPs were merged into 49 QTL,of which eight were multi-environment stable QTL and 27 were located near previously reported QTL.A set of 135 candidate genes near the 49 QTL included TaBOX(F-box family protein)and TaERF(ethylene-responsive transcription factor).A Tabox mutant was more sensitive to low-N stress than the wild-type plant.We developed two functional markers for Hap 1,the favorable allele of TaBOX. | Huawei Shi Weichong Wang Lifeng Gao Jirong Wu Chengmei Hu Huishu Yan Yugang Shi Ning Li Youzhi Ma Yongbin Zhou Zhaoshi Xu Jun Chen Wensi Tang Kai Chen Daizhen Sun Yuxiang Wu Ming Chen | 2024 | The Crop Journal2024，12，1： | 0 |
| 14 | Comparison of the Detection Results of Salmonellae in Samples by Two Methods显示文摘Salmonellae samples provided by FAPAS were detected by VIDAS and GB 4789.4-2016,respectively.The advantages and disadvantages of each detection method were discussed in the paper,so as to provide theoretical support for the detection of Salmonellae. | Jian LI Chengmei WANG | 2020 | Agricultural Biotechnology2020，9，4： | 0 |
| 15 | Pollution and Quality Control of Mycotoxins in Foods and Feeds显示文摘Mycotoxins are a kind of secondary metabolites and the most polluting biotoxins in food and feed pollution,causing great losses to people's lives and economy.This study analyzed the residues of mycotoxins in foods and feeds in a certain area,so as to understand the food safety situation in the region and provide a strong basis for food and drug supervision and management.Quality control in the analysis process is the basis for ensuring real and effective data.This study carried out a specific analysis on the contamination of mycotoxins and the quality control in the process. | Xiaoling LIU Chengmei WANG | 2019 | Agricultural Biotechnology2019，8，3： | 0 |
| 16 | Influences of Meteorological Conditions on Interannual Variations of Particulate Matter Pollution during Winter in the Beijing–Tianjin–Hebei Area显示文摘To investigate the interannual variations of particulate matter(PM) pollution in winter, this paper examines the pollution characteristics of PM with aerodynamic diameters of less than 2.5 and 10 μm(i.e., PM_(2.5) and PM10), and their relationship to meteorological conditions over the Beijing municipality, Tianjin municipality, and Hebei Province—an area called Jing–Jin–Ji(JJJ, hereinafter)—in December 2013–16. The meteorological conditions during this period are also analyzed. The regional average concentrations of PM_(2.5)(PM10) over the JJJ area during this period were 148.6(236.4), 100.1(166.4), 140.5(204.5), and 141.7(203.1) μg m^(–3), respectively. The high occurrence frequencies of cold air outbreaks, a strong Siberian high, high wind speeds and boundary layer height, and low temperature and relative humidity, were direct meteorological causes of the low PM concentration in December 2014. A combined analysis of PM pollution and meteorological conditions implied that control measures have resulted in an effective improvement in air quality. Using the same emissions inventory in December 2013–16, a modeling analysis showed emissions of PM_(2.5) to decrease by 12.7%, 8.6%, and 8.3% in December 2014, 2015, and 2016, respectively,each compared with the previous year, over the JJJ area. | Jianjun HE Sunling GONG Hongli LIU Xingqin AN Ye YU Suping ZHAO Lin WU Congbo SONG Chunhong ZHOU Jie WANG Chengmei YIN Lijuan YU | 2017 | Journal of Meteorological Research2017，31，6： | 0 |
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