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126篇 您的检索式:作者名="Chuan Tang"
    题名 作者 年代 出处 被引量
1粉防己碱抑制前列腺癌细胞迁移和侵袭并通过诱导凋亡抑制细胞增殖显示文摘粉防己碱作为一种传统的中药,在多种肿瘤细胞中呈现显著的抗肿瘤活性。然而,粉防己碱在前列腺癌细胞中的作用却知之甚少,且其作用于前列腺癌的具体机制也尚未有人阐述。为了探究粉防己碱对前列腺癌DU145和PC-3两种细胞系生长抑制、凋亡诱导、迁移和侵袭抑制等方面的作用,通过MTT实验和克隆形成实验检测其对前列腺癌细胞的生长抑制能力,采用流式细胞仪检测其对前列腺癌细胞的凋亡诱导作用。后通过Western blotting实验检测粉防己碱处理后两种前列腺癌细胞系中PARP、Caspase-3、Akt、p-Akt、Bcl-2、Bax等蛋白的表达情况。而细胞划痕实验和transwell侵袭实验则分别用来检测粉防己碱对前列腺癌细胞的迁移和侵袭能力。结果显示,粉防己碱可剂量依赖性和时间依赖性地抑制前列腺癌细胞系DU145和PC-3的生长;且经粉防己碱处理后,两种前列腺癌细胞系的细胞克隆数明显受到抑制。且粉防己碱可抑制两种前列腺癌细胞系的侵袭,并显著抑制其迁移能力。由此可知,粉防己碱对前列腺癌细胞的增殖、迁移和侵袭有显著抑制作用。另外,粉防己碱可剂量依赖性地诱导前列腺癌细胞的凋亡,且此过程是通过caspase级联反应的激活和PI3K-Akt信号通路的抑制而得以实现的。上述结果提示粉防己碱在临床中可作为前列腺癌治疗的一种潜在治疗药物。Wei Liu Bo KOU Zhen-Kun Ma Xiao-Shuang Tang Chuan Lv Min Ye Jia-Qi Chen Lei Li Xin-Yang Wang Da-Lin He 2015Asian Journal of Andrology2015,17,5:18
2Study of angiogenesis induced by metastatic and non-metastatic liver cancer by corneal micropocket model in nude mice显示文摘METHODSCornealmicropocketswerecreatedinnudemice.Tumortissuesandlivertissueswereimplantedintothecornealmicropockets.Angiogenes...SUN Hui Chuan, LI Xiao Ming, XUE Qiong, CHEN Jun, GAO Dong Mei and TANG Zhao You 1999World Journal of Gastroenterology1999,5,2:17
3Emergency assessment of seismic landslide susceptibility: a case study of the 2008 Wenchuan earthquake affected area显示文摘The 8.0 Mw Wenchuan earthquake triggered widespread and large scale landslides in mountainous regions.An approach was used to map and assess landslide susceptibility in a given area.A numerical rating system was applied to fi ve factors that contribute to slope instability.Factors such as lithology,topography,streams and faults have an important influence as event-controlling factors for landslide susceptibility assessment.A f inal map is provided to show areas of low,medium,and high landslide susceptibility.Areas identifi ed as having high landslide susceptibility were located in the central,northeastern,and far south regions of the study area.The assessment results will help decision makers to select safe sites for emergency placement of refuges and plan for future reconstruction.The maps may also be used as a basis for landslide risk management in the study area.Tang Chuan,Zhu Jing and Liang Jingtao State Key Laboratory of Geo-Hazard Prevention,Chengdu University of Technology,Chengdu 610059,China Professor Associate Professor Graduate Student 2009Earthquake Engineering and Engineering Vibration2009,8,2:16
4Debris Flow Susceptibility Assessment Using a Probabilistic Approach:A Case Study in the Longchi Area, Sichuan Province, China显示文摘The Longchi area with the city of Dujiangyan, in the Sichuan province of China, is composed of Permian stone and diorites and Triassic sandstones and mudstones intercalated with slates. An abundance of loose co-seismic materials were present on the slopes after the May 12, 2008 Wenchuan earthquake, which in later years served as source material for rainfall-induced debris flows or shallow landslides. A total of 48 debris flows, all triggered by heavy rainfall on 13 th August 2010, are described in this paper. Field investigation, supported by remote sensing image interpretation, was conducted to interpret the co-seismic landslides in the debris flow gullies. Specific characteristics of the study area such as slope, aspect, elevation, channel gradient, lithology, and gully density were selected for the evaluation of debris flow susceptibility. A score was given to all the debris flow gullies based on the probability of debris flow occurrence for the selected factors. In order to get the contribution of the different factors, principal component analyses were applied. A comprehensive score was obtained for the 48 debris flow gullies which enabled us to make a susceptibility map for debris flows with three classes. Twenty-two gullies have a high susceptibility, twenty gullies show a moderate susceptibility and six gullies have a low susceptibility for debris flows.CHANG Ming TANG Chuan ZHANG Dan-dan MA Guo-chao 2014Journal of Mountain Science2014,11,4:16
5Co-seismic Landslide Inventory and Susceptibility Mapping in the 2008 Wenchuan Earthquake Disaster Area,China显示文摘The Ms 8.0 May 12,2008 Wenchuan earthquake triggered tens of thousands of landslides.The widespread landslides have caused serious casualties and property losses,and posed a great threat to post-earthquake reconstruction.A spatial database,inventoried 43,842 landslides with a total area of 632 km 2,was developed by interpretation of multi-resolution remote sensing images.The landslides can be classified into three categories:swallow,disrupted slides and falls;deep-seated slides and falls,and rock avalanches.The correlation between landslides distribution and the influencing parameters including distance from co-seismic fault,lithology,slope gradient,elevation,peak ground acceleration(PGA) and distance from drainage were analyzed.The distance from co-seismic fault was the most significant parameter followed by slope gradient and PGA was the least significant one.A logistic regression model combined with bivariate statistical analysis(BSA) was adopted for landslide susceptibility mapping.The study area was classified into five categories of landslide susceptibility:very low,low,medium,high and very high.92.0% of the study area belongs to low and very low categories with corresponding 9.0% of the total inventoried landslides.Medium susceptible zones make up 4.2% of the area with 17.7% of the total landslides.The rest of the area was classified into high and very high categories,which makes up 3.9% of the area with corresponding 73.3% of the total landslides.Although the susceptibility map can reveal the likelihood of future landslides and debris flows,and it is helpful for the rebuilding process and future zoning issues.LI Wei-le HUANG Run-qiu TANG Chuan XU Qiang Cees van WESTEN 2013Journal of Mountain Science2013,10,3:15
6Surgical treatment of hepatocellular carcinoma with inferior vena cava tumor thrombus: a new classification for surgical guidance显示文摘BACKGROUND: Hepatic resection is the main treatment modality for hepatic tumors. Advances in diagnostic technique, preoperative preparation, surgical technique, and postoperative management increased the success rate. The present study aimed to evaluate hepatectomy and resection of inferior vena cava tumor thrombus (IVCTT) in patients with hepatocellular carcinoma, and the relationship between IVCTT classification and selection of surgical technique. METHODS: We retrospectively reviewed 13 patients with hepatocellular carcinoma who had undergone hepatectomy with IVCTT resection between May 1997 and August 2009. Age, gender, diagnosis, findings of physical examination, results of preoperative laboratory investigations, radiological examination, criteria for resection, postoperative pathological results, incisions, operative technique, intraoperative transfusion, drains, and intraoperative and postoperative complications were evaluated for all patients. RESULTS: Type Ⅰ IVCTT (10 patients) was posterior to the liver and below the diaphragm; type Ⅱ IVCTT (2 patients) was above the diaphragm but still outside the atrium; and type Ⅲ IVCTT (1 patient) was above the diaphragm and in the right atrium. Type Ⅰ was treated by radical hepatectomy and removal of IVCTT with total hepatic vascular exclusion. Type Ⅱ was treated by radical hepatectomy and removal of IVCTT by incision of the diaphragm. Type Ⅲ was treated by hepatectomy and resection of the thrombus from the right atrium under cardiopulmonary bypass. There were no surgical complications and one patient has been survived for 4 years with cancer-free status. The median survival time was 18.2 months, and the 1-and 2-year survival rates were 53.8% and 15.4%, respectively. CONCLUSION: Surgical treatment is safe and feasible for treatment of IVCTT in patients with hepatocellular carcinoma, and surgical resectability can be judged according to the classification of tumor thrombus.Ai-Jun Li Wei-Ping Zhou Chuan Lin Xi-Long Lang Zhen-Guang Wang Xiao-Yu Yang Qing-He Tang Ran Tao Meng-Chao Wu 2013Hepatobiliary & Pancreatic Diseases International2013,12,3:15
7Human umbilical cord blood stem cell transplantation for the treatment of chronic spinal cord injury Electrophysiological changes and long-term efficacy显示文摘Stem cell transplantation can promote functional restoration following acute spinal cord injury (injury time < 3 months), but the safety and long-term efficacy of this treatment need further exploration. In this study, 25 patients with traumatic spinal cord injury (injury time > 6 months) were treated with human umbilical cord blood stem cells via intravenous and intrathecal injection. The follow-up period was 12 months after transplantation. Results found that autonomic nerve functions were restored and the latent period of somatosensory evoked potentials was reduced. There were no severe adverse reactions in patients following stem cell transplantation. These experimental findings suggest that the transplantation of human umbilical cord blood stem cells is a safe and effective treatment for patients with traumatic spinal cord injury.Liqing Yao Chuan He Ying Zhao Jirong Wang Mei Tang Jun Li Ying Wu Lijuan Ao Xiang Hu 2013Neural Regeneration Research2013,8,5:14
8How Work Organization Affects the Prevalence of WMSDs: A Case-control Study显示文摘Objective In this study, we aimed at exploring the association between work-related musculoskeletal disorders(WMSDs) and work organization based on a case-control study. Methods A total of 1938 workers who claimed to suffer from WMSDs were selected from Beijing, Henan, Hubei, and the Guangdong province. The control group consisted of 2009 workers employed in similar industries without severe disease or musculoskeletal discomforts. We used a modified version of the questionnaire developed by the NMQ and the DMQ to investigate individual and work-related factors. Results A total of 13 variables(P<0.1) were selected by the chi-square test and finally, 7 variables entered into the equation, with 6 variables reaching statistical significance(P<0.05). The odds ratios(OR) of ‘work changing with season' and ‘sufficient rest time' did not reach 1(0.749 and 0.441, respectively). In addition, ‘sufficient rest time' seemed to be the stronger protective factor according to its higher standardized coefficient. And ‘repetitive work every minute', ‘constantly repetitive work'(every day), ‘shortage of site personnel', and ‘often switching shifts with others' seemed to be the risk factors. Conclusion Work organization may have comprehensive effects on the occurrence of WMSDs. This pattern of associations suggests that further investigation into the mechanism of how work organization affects the prevalence of WMSDs is required.LIU Lu CHEN Song Gen TANG Shi Chuan WANG Sheng HE Li Hua GUO Ze Hua LI Jing Yun YU Shan Fa WANG Zhong Xu 2015Biomedical and Environmental Sciences2015,28,9:11
9Early vitrectomy combined with pan retinal photocoagulation, anti-vascular endothelial growth factor, and gradual cyclophotocoagulation for treatment of neovascular glaucoma显示文摘To the editor: Neovascular glaucoma (NVG) is refractory glaucoma characterized by neovascularization of iris or anterior chamber angle, which often leads to dramatic elevation of intraocular pressure (IOP) and severe vision loss.[1] Series of studies have been reported regarding managing NVG with anti-vascular endothelial growth factor (VEGF) therapy or in combination with anti-glaucoma surgery.[2,3,4] However, the effect of anti-VEGF seems only temporary and it does not improve the prognosis in the long term.[5] Therefore, pan retinal photocoagulation (PRP) remains necessary for improving long term prognosis.[5] However, it is not easy to complete PRP early in NVG patients due to corneal edema, hyphema, or vitreous hemorrhage. We conducted this prospective interventional case series study to propose a protocol which could confine NVG in an early stage. The aims of our treatment modalities included that controlling IOP immediately, complete PRP as soon as possible, anti-VEGF as adjuvant and controlling residual glaucoma with gradual cyclophotocoagulation.Chuan Sun Hong-Song Zhang Yu-Jie Yan Tong Zhao Ai-Hong Li Yan Tang Zhi-Jun Wang 2019Chinese Medical Journal2019,,20:8
10Progress in ENSO prediction and predictability study显示文摘ENSO is the strongest interannual signal in the global climate system with worldwide climatic, ecological and societal impacts. Over the past decades, the research about ENSO prediction and predictability has attracted broad attention. With the development of coupled models, the improvement in initialization schemes and the progress in theoretical studies, ENSO has become the most predictable climate mode at the time scales from months to seasons. This paper reviews in detail the progress in ENSO predictions and predictability studies achieved in recent years. An emphasis is placed on two fundamental issues: the improvement in practical prediction skills and progress in the theoretical study of the intrinsic predictability limit. The former includes progress in the couple models, data assimilations, ensemble predictions and so on, and the latter focuses on efforts in the study of the optimal error growth and in the estimate of the intrinsic predictability limit.Youmin Tang Rong-Hua Zhang Ting Liu Wansuo Duan Dejian Yang Fei Zheng Hongli Ren Tao Lian Chuan Gao Dake Chen Mu Mu 2018National Science Review2018,5,6:8
11Detection of serum IgM and IgG for COVID-19 diagnosis显示文摘Dear Editor,Infection with the novel coronavirus(SARS-CoV-2,which is the virus responsible for the coronavirus disease 2019(COVID-19))was first reported in Wuhan,China on December 31,2019.The outbreak of COVID-19 remains ongoing and was linked to more than 80,000 infected patients and more than 3,000 deaths in China as of March 7,2020(Holshue et al.,2020).Ling Zhong Junlan Chuan Bo Gong Ping Shuai Yu Zhou Yi Zhang Zhilin Jiang Dingding Zhang Xiaoqi Liu Shi Ma Yi Huang He Lin Qingwei Wang Lulin Huang Dan Jiang Fang Hao Juan Tang Chunqi Zheng Hua Yu Zhibin Wang Qi Jiang Tao Zeng Mei Luo Fanwei Zeng Fanxin Zeng Jianghai Liu Junxi Tian Yu Xu Tengxiang Long Kaiju Xu Xingxiang Yang Yuping Liu Yi Shi Li Jiang Zhenglin Yang 2020Science China(Life Sciences)2020,63,5:8
12Recent advances in spinel-type electrocatalysts for bifunctional oxygen reduction and oxygen evolution reactions显示文摘The demand for efficient and environmentally-benign electrocatalysts that help availably harness the renewable energy resources is growing rapidly. In recent years, increasing insights into the design of water electrolysers, fuel cells, and metal–air batteries emerge in response to the need for developing sustainable energy carriers, in which the oxygen evolution reaction and the oxygen reduction reaction play key roles. However, both reactions suffer from sluggish kinetics that restricts the reactivity. Therefore, it is vital to probe into the structure of the catalysts to exploit high-performance bifunctional oxygen electrocatalysts. Spinel-type catalysts are a class of materials with advantages of versatility, low toxicity, low expense, high abundance, flexible ion arrangement, and multivalence structure. In this review, we afford a basic overview of spinel-type materials and then introduce the relevant theoretical principles for electrocatalytic activity, following that we shed light on the structure–property relationship strategies for spinel-type catalysts including electronic structure, microstructure, phase and composition regulation,and coupling with electrically conductive supports. We elaborate the relationship between structure and property, in order to provide some insights into the design of spinel-type bifunctional oxygen electrocatalysts.Xiao-Meng Liu Xiaoyang Cui Kamran Dastafkan Hao-Fan Wang Cheng Tang Chuan Zhao Aibing Chen Chuanxin He Minghan Han Qiang Zhang 2021Journal of Energy Chemistry2021,30,2:7
13Rapid Susceptibility Mapping of Co-seismic Landslides Triggered by the 2013 Lushan Earthquake Using the Regression Model Developed for the 2008 Wenchuan Earthquake显示文摘The primary objective of landslide susceptibility mapping is the prediction of potential landslides in landslide-prone areas.The predictive power of a landslide susceptibility mapping model could be tested in an adjacent area of similar geoenvironmental conditions to find out the reliability.Both the 2008 Wenchuan Earthquake and the 2013 Lushan Earthquake occurred in the Longmen Mountain seismic zone,with similar topographical and geological conditions.The two earthquakes are both featured by thrust fault and similar seismic mechanism.This paper adopted the susceptibility mapping model of co-seismic landslides triggered by Wenchuan earthquake to predict the spatial distribution of landslides induced by Lushan earthquake.Six influencing parameters were taken into consideration: distance from the seismic fault,slope gradient,lithology,distance from drainage,elevation and Peak Ground Acceleration(PGA).The preliminary results suggested that the zones with high susceptibility of coseismic landslides were mainly distributed in the mountainous areas of Lushan,Baoxing and Tianquan counties.The co-seismic landslide susceptibility map was completed in two days after the quake and sent to the field investigators to provide guidance for rescue and relief work.The predictive power of the susceptibility map was validated by ROC curve analysis method using 2037 co-seismic landslides in the epicenter area.The AUC value of 0.710 indicated that the susceptibility model derived from Wenchuan Earthquake landslides showed good accuracy in predicting the landslides triggered by Lushan earthquake.LI Wei-le HUANG Run-qiu XU Qiang TANG Chuan 2013Journal of Mountain Science2013,10,5:7
14A Study of Tensile Strength Tests of Arborous Species Root System in Forest Engineering Technique of Shallow Landslide显示文摘One experiment was conducted, through tensile tests of Albazzia and Eucalypt roots culled from the fields. The other experiment was conducted, by testing anti-drawing strength of these root systems in the Albazzia and Eucalypt lands. These two experiments had an aim to give insights into the maximum tensile strength and anti-drawing strength of the root systems. Results indicated that the maximum tensile strength of root system is in an exponential relation with the diameter of root system while the maximum tensile strength is positively correlative with the diameter of root system. Anti-drawing force of root system together with root diameter, length, and soil bulk density are folded into a regression equation in an attempt to figure out the static friction coefficient between root system and its ambient soil.YANG Yonghong LIU Shuzhen WANG Chenghua TANG Chuan 2006Wuhan University Journal of Natural Sciences2006,11,4:6
15The Two Main Mechanisms of Glacier Lake Outburst Flood in Tibet,China显示文摘With the global warming,the disasters of Glacier Lake Outburst Flood(GLOF) have taken place frequently in Tibet in recent years and attracted more and more attention.A systematic survey was conducted on the 19 GLOFs in Tibet to study their two main mechanisms.Investigations indicated that all the events occurred in end-moraine lakes,and the outburst occurred partially and instantly.And the breach had the shape of an arc or a trapezoid in overflow outburst and its top width was 3-5 times more than the height.The two main mechanisms of GLOFs in Tibetan end-moraine Lake were overflow and piping,and the overflow mechanism caused by iceberg collapse was dominated in most cases.A formula was proposed to calculate the critical thickness of iceberg tongue that determines the collapse.Granular analysis of the moraine materials revealed that seepage deformation is crucial in the outburst process.Finally,we conducted a case study of the Guangxiecuo Lake to show its possible process of outburst and estimated the peak discharge of the resulted flood.LIU Jing-jing TANG Chuan CHENG Zun-lan 2013Journal of Mountain Science2013,10,2:6
16CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta,alpha,beta,and gamma显示文摘SARS-CoV-2 mutations contribute to increased viral transmissibility and immune escape,compromising the effectiveness of existing vaccines and neutralizing antibodies.An in-depth investigation on COVID-19 pathogenesis is urgently needed to develop a strategy against SARS-CoV-2 variants.Here,we identified CD147 as a universal receptor for SARS-CoV-2 and its variants.Meanwhile,Meplazeumab,a humanized anti-CD147 antibody,could block cellular entry of SARS-CoV-2 and its variants-alpha,beta,gamma,and delta,with inhibition rates of 68.7,75.7,52.1,52.1,and 62.3%at 60μg/ml,respectively.Furthermore,humanized CD147 transgenic mice were susceptible to SARS-CoV-2 and its two variants,alpha and beta.When infected,these mice developed exudative alveolar pneumonia,featured by immune responses involving alveoli-infiltrated macrophages,neutrophils,and lymphocytes and activation of IL-17 signaling pathway.Mechanistically,we proposed that severe COVID-19-related cytokine storm is induced by a'spike protein-CD147-CyPA signaling axis':Infection of SARS-CoV-2 through CD147 initiated the JAK-STAT pathway,which further induced expression of cyclophilin A(CyPA);CyPA reciprocally bound to CD147 and triggered MAPK pathway.Consequently,the MAPK pathway regulated the expression of cytokines and chemokines,which promoted the development of cytokine storm.Importantly,Meplazumab could effectively inhibit viral entry and inflammation caused by SARS-CoV-2 and its variants.Therefore,our findings provided a new perspective for severe COVID-19-related pathogenesis.Furthermore,the validated universal receptor for SARS-CoV-2 and its variants can be targeted for COVID-19 treatment.Jiejie Geng Liang Chen Yufeng Yuan Ke Wang Youchun Wang Chuan Qin Guizhen Wu Ruo Chen Zheng Zhang Ding Wei Peng Du Jun Zhang Peng Lin Kui Zhang Yongqiang Deng Ke Xu Jiangning Liu Xiuxuan Sun Ting Guo Xu Yang Jiao Wu Jianli Jiang Ling Li Kun Zhang Zhe Wang Jing Zhang Qingguo Yan Hua Zhu Zhaohui Zheng Jinlin Miao Xianghui Fu Fengfan Yang Xiaochun Chen Hao Tang Yang Zhang Ying Shi Yumeng Zhu Zhuo Pei Fei Huo Xue Liang Yatao Wang Qingyi Wang Wen Xie Yirong Li Mingyan Shi Huijie Bian Ping Zhu Zhi-Nan Chen 2021Signal Transduction and Targeted Therapy2021,6,10:6
17Approximate Iteration Detection and Precoding in Massive MIMO显示文摘Massive multiple-input multiple-output provides improved energy efficiency and spectral efficiency in 5 G. However it requires large-scale matrix computation with tremendous complexity, especially for data detection and precoding. Recently, many detection and precoding methods were proposed using approximate iteration methods, which meet the demand of precision with low complexity. In this paper, we compare these approximate iteration methods in precision and complexity, and then improve these methods with iteration refinement at the cost of little complexity and no extra hardware resource. By derivation, our proposal is a combination of three approximate iteration methods in essence and provides remarkable precision improvement on desired vectors. The results show that our proposal provides 27%-83% normalized mean-squared error improvement of the detection symbol vector and precoding symbol vector. Moreover, we find the bit-error rate is mainly controlled by soft-input soft-output Viterbi decoding when using approximate iteration methods. Further, only considering the effect on soft-input soft-output Viterbi decoding, the simulation results show that using a rough estimation for the filter matrix of minimum mean square error detection to calculating log-likelihood ratio could provideenough good bit-error rate performance, especially when the ratio of base station antennas number and the users number is not too large.Chuan Tang Yerong Tao Yancang Chen Cang Liu Luechao Yuan Zuocheng Xing 2018China Communications2018,15,5:5
18Plant community composition and interspecific relationships among dominant species on a post-seismic landslide in Hongchun Gully, China显示文摘The 5.12 Earthquake in 2008 and 8.14 Debris Flow in 2010 resulted in large-scale landslides that disturbed vast areas of vegetation in the Hongchun Gully, Wenchuan County, China. To define the specific characteristics of vegetation restoration during natural recovery after catastrophic events,vegetation species composition and interspecific associations were investigated on this typical landslide. Field survey data selected from a total of 51 sample plots belonged to seven belt transects and were analysed by Schluter's variance ratio, pearson's chi-squared test, Spearman's correlation coefficients and ecological species groups. Plant communities on the landslide consisted of 78 species, 65 genera and52 families. Of the total of 78 species, 25 are identified as dominant species, among which Camptotheca acuminate, Toxicodendron vernicifluum, Coriaria nepalensis, Robinia pseudoacacia, Buddleja alternifolia, Anemone vitifolia and Nephrolepis auriculata play a constructive role during the natural afforestation. Moreover, according to environmental and ecological factors, these 25 dominant species could be divided into four ecological species groups.This study found that even though the landslide had frequently suffered from interference due to heavy rain, the vegetation succession processes are ongoing,and it is now at a shrub–herb community succession stage, which indicates that vegetation can naturally recover in the denuded sites. This study provides a useful insight into the ecological interactions and interdependence between plant species during the natural recovery of vegetation and provides valuable information on vegetation recovery modelling in the landslide area.HUANG You-you HAN Han TANG Chuan LIU Shou-jiang 2017Journal of Mountain Science2017,14,10:5
19Commissioning the photocathode radio frequency gun:a candidate electron source for Hefei Advanced Light Facility显示文摘The Hefei Advanced Light Facility(HALF)proposed by the National Synchrotron Radiation Laboratory(NSRL)is a diffraction-limited storage ring(DLSR),which plans to use a full energy linac as the injector.To ensure injection efficiency,the injection beam needs to have low emittance.Therefore,a photocathode radio frequency(RF)gun was developed in the HALF R&D project.The gun is designed to deliver high-quality electron bunches with a typically 0.5 nC charge and~4.5 MeV energy with low emittance.The initial system commission with an electron beam was completed at the end of 2020,and a stable 1.2–1.4 mm.mrad emittance with a bunch charge of 500 pC was demonstrated.In this paper,we report the experimental results and experience obtained during the commission,including the RF gun,drive laser system,and beam diagnostics.Wen-Xing Wang Cheng Li Zhi-Gang He Shan-Cai Zhang Rui-Xuan Huang Wei-Wei Li Ping Lu Chuan Li Lei-Lei Tang Feng-Lei Shang Fang-Fang Wu Da-Chun Jia Hai-Yan Zhang Wei Wang 2022Nuclear Science and Techniques2022,33,3:4
20Spatial distribution analysis of landslides triggered by the 2013-04-20 Lushan earthquake,China显示文摘The 2013-04-20 Lushan earthquake(seismic magnitude Ms 7.0 according to the State Seismological Bureau)induced a large number of landslides.In this study,spatial characteristics of landslides are developed by interpreting digital aerial photography data.Seven towns near the epicenter,with an area of about 11.11 km2,were severely affected by the earthquake,and 703 landslides were identified from April 24,2013 aerial photography data over an area of 1.185 km2.About 55.56% of the landslide area was less than 1000 m2,whereas about 3.23 % was more than 10,000 m2.Rock falls and shallow landslides were the most commonly observed types in the study area,and were primarily located in the center of Lushan County.Most landslide areas were widely distributed near river channels and along roads.Five main factors were chosen to study the distribution characteristics of landslides:elevation,slope gradients,fault,geologic unit and river system.The spatial distribution of coseismal landslides is studied statistically using both landslide point density(LPD),defined as the number of landslides(LS Number)per square kilometer,and landslide area density(LAD),interpreted as the percentage of landslides area affected by earthquake.The results show that both LPD and LAD have strong positive correlations with five main factors.Most landslides occurred in the gradient range of 40°-50° and an elevation range of 1.0-1.5 km above sea level.Statistical results also indicate that landslides were mainly formed in soft rocks such as mudstone and sandstone,and concentrated in IX intensity areas.Chang Ming Tang Chuan Xia Chenhao Fang Qunsheng 2016Earthquake Engineering and Engineering Vibration2016,15,1:4
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