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| 1 | LEAFY HEAD2,which encodes a putative RNA-binding protein,regulates shoot development of rice显示文摘在植物的开发期间,更高的植物连续地在常规空间、时间的模式形成新叶子。有反常的叶的异种发展模式不仅提供大卓见进理解植物建筑学的规章的机制,而且充实方法到它庄稼产量能被改进的修正。这里,我们报导了米饭 leafy-head2 (lhd2 ) 的描述展览弄短的异种阶段的 plastochron,侏儒症,减少的 tiller 数字,和失败转移从对繁殖生长植物。而减少的 tiller 数字是 tiller 芽长出的抑制的后果,解剖、组织学的学习表明在 lhd2 的叶子的快速的出现从叶 primordia 的快速的开始被结果。分子、基因的分析证明 LHD2 与 67% 类似编码通常认为的 RNA 有约束力的蛋白质到玉米 TE1。染色体规模表示侧面在之间的比较野类型并且 lhd2 植物建议 LHD2 可以通过 KNOX 和荷尔蒙相关的基因调整米饭射击开发。LHD2 变化和 LHD2 的保存表示模式引起的类似的显型在在草控制时间的叶开始显示了保存机制。 | Guo Sheng Xiong Xing Ming Hu Yong Qing Jiao Yan Chun Yu Cheng Cai Chu Jia Yang Li Qian Qian Yong Hong Wang | 2006 | Cell Research2006，16，3： | 11 |
| 2 | Comparison of nonhuman primates identified the suitable model for COVID-19显示文摘Identification of a suitable nonhuman primate(NHP)model of COVID-19 remains challenging.Here,we characterized severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection in three NHP species:Old World monkeys Macaca mulatta(M.mulatta)and Macaca fascicularis(M.fascicularis)and New World monkey Callithrix jacchus(C.jacchus).Infected M.mulatta and M.fascicularis showed abnormal chest radiographs,an increased body temperature and a decreased body weight.Viral genomes were detected in swab and blood samples from all animals.Viral load was detected in the pulmonary tissues of M.mulatta and M.fascicularis but not C.jacchus.Furthermore,among the three animal species,M.mulatta showed the strongest response to SARS-CoV-2,including increased inflammatory cytokine expression and pathological changes in the pulmonary tissues.Collectively,these data revealed the different susceptibilities of Old World and New World monkeys to SARS-CoV-2 and identified M.mulatta as the most suitable for modeling COVID-19. | Shuaiyao Lu Yuan Zhao Wenhai Yu Yun Yang Jiahong Gao Junbin Wang Dexuan Kuang Mengli Yang Jing Yang Chunxia Ma Jingwen Xu Xingli Qian Haiyan Li Siwen Zhao Jingmei Li Haixuan Wang Haiting Long Jingxian Zhou Fangyu Luo Kaiyun Ding Daoju Wu Yong Zhang Yinliang Dong Yuqin Liu Yinqiu Zheng Xiaochen Lin Li Jiao Huanying Zheng Qing Dai Qiangming Sun Yunzhang Hu Changwen Ke Hongqi Liu Xiaozhong Peng | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 5 |
| 3 | Prevalence of Hyperuricemia and Associated Factors in the Yi Farmers and Migrants of Southwestern China: A Cross-sectional Study显示文摘Hyperuricemia(HUA) is a common metabolic disease caused by increased formation or reduced excretion of uric acid. Although HUA does not cause direct damage to the body, it is closely related to the occurrence of various diseases, including gout,hypertension, diabetes mellitus, metabolic syndrome, and chronic kidney disease. | WANG Qing Qing WAN Shao Ping SHAN Guang Liang WU Wen Bo YONG Zheng Ping PEI Jiao | 2020 | Biomedical and Environmental Sciences2020，33，6： | 4 |
| 4 | Comparing community birdwatching and professional bird monitoring with implications for avian diversity research: a case study of Suzhou, China显示文摘Background:In the past decades,birdwatching as a hobby developed rapidly and produced ample scientific records that have aided conservation efforts.Therefore,it is increasingly attractive to promote avian research by providing data from birdwatching.Methods:We compared records from 16 years of community birdwatching and a 1-year formalized bird monitoring in Suzhou,China to study the similarities and differences between the two monitoring methods.Results:We showed that within the 325 bird species recorded by the two methods,an annual average of 108 species were documented by community science and 223 bird species were recorded by 1-year formalized monitoring.Measured by the number of bird species recorded per survey trip,the bird monitoring activity of community birdwatchers was significantly lower.Furthermore,the monitoring intensity of community birdwatching measured as the average survey trips per site each survey year was also lower than that of formalized bird monitoring.In addition,community birdwatchers preferred urban landscapes to rural areas.Conclusions:Community birdwatching could record the majority of local birds and complements the professional surveys in avian research.Well designed and coordinated community science can be used to expand the knowledge about avian distribution and population dynamics.These findings are critical for the development of conservation science with regard to community involvement. | Yan Zhou Anping Chen Jenny QOuyang Yanlin Liu Aiyu Zheng Zaixi Yang Yong Zhang Bin Wang Yifei Jia Shengwu Jiao Qing Zeng Changhu Lu | 2020 | Avian Research2020，11，2： | 2 |
| 5 | Synthesis of a novel multivalent galactoside with high hepatocyte targeting for gene delivery显示文摘A novel bifunctional glycolipid which carried a cluster of thiogalactosides as the hepatocyte targeting ligand for gene delivery was prepared. Hexa-antennary alcohol 1 was used as the core scaffold to attach a cholesterol molecule by a poly(ethylene glycol) chain, while its remaining branches were linked with five acetylgalactosides, which would be deacetylated later to produce penta- antennary galactoside. Liposome containing the galactoside showed high affinity and transfection activity in hepatoma cells HepG2. | Qing Lin Jiang Li Hai Lei Chen Jiao Lu Zhi Rong Zhang Yong Wu | 2008 | Chinese Chemical Letters2008，19，2： | 1 |
| 6 | Expert Consensus on Assessment of Rupture Factors in Unruptured Intracranial Aneurysms显示文摘Intracranial aneurysms have a high prevalence in the population and are associated with high rates of disability and mortality after rupture.It is essential to assess the rupture risk of unruptured intracranial aneurysms by selecting appropriate morphological parameters.However,there is still a need for consistent evidence-based medicine to provide a clinical reference.Therefore,the expert group has jointly written this consensus based on literature review and clinical experience,aiming to provide a standardized reference for predicting the development of intracranial aneurysms and evaluating their rupture risk factors. | Ren-Ya Zhan Jian-Wei Pan Jian Shen Yu Zhu Jie Shen Fan Wu Hong-Wei He Hua Yang Jing Dai Xiang-Yu Wang Jun Ren Ying Xia Wei Wang Li-Qun Jiao Chuan-Lu Jiang Qing Lan Yi-Rong Wang Qi-Chuan Zhuge Guo-Hua Mao Hua Lu Xin-Gen Zhu Wen-Hua Yu Yong Jing Xiang-Dong Zhu | 2022 | Journal of Cerebrovascular Disease2022，5，3： | 0 |
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