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| 1 | Gastrointestinal stromal tumors in a cohort of Chinese patients in Hong Kong显示文摘瞄准:用香港汉语调查流行和胃肠的基质肿瘤(大意) 的临床的模式,并且估计发病率的 CD117 的介绍的影响。方法:从 Yan Chai 医院的病理的部门的数据库, 47 个病人,在这研究与到 2003 年 12 月的从 1995 年 9 月的大意被包括。十大意在 CD117 的介绍前被诊断。临床的特征,肿瘤特征,和治疗被分析。预言肿瘤的因素联系了死亡或复发与比例的危险建模的考克斯一起被学习。结果:病人包括了 26 男性和 21 女性,与 66.6 年的吝啬的年龄(SD 13.1,范围 29-87 年) 。大意的估计的流行每 100,000 个人是 13.4-15.6,与每 100,000 个人的 1.68-1.96 的年度发生。在 CD117 的介绍前后的大意的年度发生每 100,000 个人是 1.1 并且 2.1 每 100,000 个人分别地。胃(34 个病人, 72.3%) 是为肿瘤的最普通的地点,由小肠列在后面(8 个病人, 17.0%) ,食管(2 个病人, 4.3%) ,网膜(2 个病人, 4.3%) 并且冒号(1 个病人, 2.1%) 。31 个病人(66%) 有完全的肿瘤切除术。十一从 16 死亡(23%) 是肿瘤相关的。中部的生存时间是 26 瞬间。五年的幸存率是 61.3% 。与肿瘤相关的死亡或复发联系的重要因素是不完全的切除术,肿瘤尺寸 5 厘米以上,侵略到转移的邻近的机关或存在。结论:在香港的大意的发生在美国比得上那,但是在芬兰比那降低。大意的真发生能在 CD117 的介绍前被低估。不完全的切除术,肿瘤尺寸 5 厘米以上,到转移的邻近的机关或存在的侵略是预言肿瘤相关的死亡或复发的因素。 | Kam Hoi Chan Chun Wing Chan Wai Hung Chow Wai Keung Kwan Chi Kwan Kong Ka Fung Mak Miu Yi Leung Lin Kiu Lau | 2006 | World Journal of Gastroenterology2006，12，14： | 12 |
| 2 | Chinese topical herbal medicine gives additive effect on pharmaceutical agent on fracture healing显示文摘OBJECTIVE:To investigate the efficacy on the combination of oral strontium ranelate(Sr R)with a topical Chinese herbal paste on facilitation of fracture healing.METHODS:An open fracture was created at the mid-shaft of the right tibia of rat.A herbal pastecalled CDR containing Honghua(Flos Carthami),Chuanxuduan(Radix Dipsaci Asperoidis)and Dahuang(Radix Et Rhizoma Rhei Palmati)was prepared.The rats were treated with either CDR topically on the fracture site,or Sr R orally,or their combinations.Bone turnover biochemical markers in serum were measured.Microarchitecture of the fracture was analyzed using micro-CT after 14 and 28 d,followed by histomorphometrical analysis.RESULTS:Micro-computed tomography analysis revealed that the combined treatment of CDR with600 mg/g Sr R significantly increased the total callus density,mineralized callus volume fraction,mineralized callus mineral content and mineralized callus density of the callus after 28 d of treatment.This result was consistent with the histomorphometrical analysis on the osteoid volume.Analysis of biochemical markers showed that the combined treatments reduced the bone resorption that occurs temporarily after fracture.CONCLUSION:This study demonstrated that the combined treatment of oral Sr R and topical CDR is effective to promote fracture healing by their additive effect on promoting bone formation and retarding bone resorption. | Siu Wing Sum Shiu Hoi Ting Shum Wai Ting Ko Chun Hay Lau Clara Bik San Hung Leung Kim Leung Ping Chung | 2019 | Journal of Traditional Chinese Medicine2019，39，6： | 4 |
| 3 | Intravenous fluid selection rationales in acute clinical management显示文摘BACKGROUND: Intravenous fluid(IVF) is commonly used in acute clinical management. This study aimed to review the choice and primary considerations in IVF prescriptions and to evaluate the adequacy of guidelines and trainings on it in the New Territories West Cluster(NTWC) of Hong Kong.METHODS: This is a descriptive study based on data collected from an online survey. Data were processed by SPSS for statistical analysis. This study focused on a general description and doctor-nurse between group comparison. Participants were asked the choice of IVF for nine acute clinical scenarios and provide reason. A 1–10 scale was used to assess the sufficiency of guideline, training and information, and time for revision on IVF prescription.RESULTS: 0.9% sodium chloride was the most familiar IVF(36%), followed by 5% Dextrose solution(26%). In the nine scenarios, the most chosen IVF was 0.9% sodium chloride(37%–61%). There was significant difference in the choice of IVF between doctors and nurses in 7 cases. The second most chosen IVF for doctors was Plasma-Lyte A while that for nurses was Gelofusine. Departmental practice was the most chosen reason to account for the prescription. The adequacy of guideline, information and training, and time for revision was rated 5. Doctors had significantly more time at work than nurses to update knowledge in IVF prescription(5.41 versus 4.57).CONCLUSION: 0.9% sodium chloride was mostly chosen. The choice of IVF was mainly based on departmental practice. Adequacy of guideline, information and training, and time for revision on IVF prescription were average, indicating significant training deficit. | Wing Yan Shirley Cheung Wai Kwan Cheung Chun Ho Lam Yeuk Wai Chan Hau Ching Chow Ka Lok Cheng Yau Hang Wong Chak Wah Kam | 2018 | World Journal of Emergency Medicine2018，9，1： | 3 |
| 4 | Early-onset primary torsional dystonia in a 4-generation Chinese family with a mutation in the DYT1 gene显示文摘Primary torsion dystonia (PTD) is a clinically and genetically heterogeneous movement disorder. At least thirteen different types of dystonia can be distinguished on a genetic basis.1 The DYT1 gene was first mapped by Ozelius et al in 1989.2 (Kramer et) al3 linked the same locus to PTD in 12 Ashkenazi Jewish families in 1990. Most patients with early-onset generalized PTD were caused by the same three base pair (GAG) deletion in the DYT1 gene on chromosome 9q34.1,4,5 The product of the gene is a protein called torsinA.5 (Although the) function of this protein is as yet uncertain, it is widely distributed throughout the brain with high levels in the substantia nigra compacta dopamine neurones. | YEUNG Wai Lan LAM Ching Wan CHENG Wai Tsoi SIN Ngai Chuen WONG Wing Kin WONG Chun Nei TSE Ka Ming FOK Tai Fai | 2005 | Chinese Medical Journal2005，，10： | 2 |
| 5 | Examining patterns of traditional chinese medicine use in pediatric oncology: A systematic review, meta-analysis and data-mining study显示文摘Background Traditional Chinese medicine(TCM)is becoming a popular complementary approach in pediatric oncology.However,few or no meta-analyses have focused on clinical studies of the use of TCM in pediatric oncology.Objective We explored the patterns of TCM use and its efficacy in children with cancer,using a systematic review,meta-analysis and data mining study.Search strategy We conducted a search of five English(Allied and Complementary Medicine Database,Embase,PubMed,Cochrane Central Register of Controlled Trials,and ClinicalTrials.gov)and four Chinese databases(Wanfang Data,China National Knowledge Infrastructure,Chinese Biomedical Literature Database,and VIP Chinese Science and Technology Periodicals Database)for clinical studies published before October 2021,using keywords related to“pediatric,”“cancer,”and“TCM.”Inclusion criteria We included studies which were randomized controlled trials(RCTs)or observational clinical studies,focused on patients aged<19 years old who had been diagnosed with cancer,and included at least one group of subjects receiving TCM treatment.Data extraction and analysis The methodological quality of RCTs and observational studies was assessed using the six-item Jadad scale and the Effective Public Healthcare Panacea Project Quality Assessment Tool,respectively.Meta-analysis was used to evaluate the efficacy of combining TCM with chemotherapy.Study outcomes included the treatment response rate and occurrence of cancer-related symptoms.Association rule mining(ARM)was used to investigate the associations among medicinal herbs and patient symptoms.Results The fifty-four studies included in this analysis were comprised of RCTs(63.0%)and observational studies(37.0%).Most RCTs focused on hematological malignancies(41.2%).The study outcomes included chemotherapy-induced toxicities(76.5%),infection rate(35.3%),and response,survival or relapse rate(23.5%).The methodological quality of most of the RCTs(82.4%)and observational studies(80.0%)was rated as“moderate.”In studies of leukemia patients,adding TCM to conventional treatment significantly improved the clinical response rate(odds ratio[OR]=2.55;95%confidence interval[CI]=1.49-4.36),lowered infection rate(OR=0.23;95%CI=0.13-0.40),and reduced nausea and vomiting(OR=0.13;95%CI=0.08-0.23).ARM showed that Radix Astragali,the most commonly used medicinal herb(58.0%),was associated with treating myelosuppression,gastrointestinal complications,and infection.Conclusion There is growing evidence that TCM is an effective adjuvant therapy for children with cancer.We proposed a checklist to improve the quality of TCM trials in pediatric oncology.Future work will examine the use of ARM techniques on real-world data to evaluate the efficacy of medicinal herbs and drug-herb interactions in children receiving TCM as a part of integrated cancer therapy. | Chun Sing Lam Li Wen Peng Lok Sum Yang Ho Wing Janessa Chou Chi-Kong Li Zhong Zuo Ho-Kee Koon Yin Ting Cheung | 2022 | Journal of Integrative Medicine2022，20，5： | 2 |
| 6 | Targeted hepatitis C screening among ex‐injection drug users in the community显示文摘 | Vincent Wai‐Sun Wong Grace Lai‐Hung Wong Angel Mei‐Ling Chim Tsz‐Fai Cheng Shirley Wing‐Yan Cheung Carol Man‐Sze Lai Kylie Joan‐Yi Szeto Sharon Tsang Stephen Ho‐Chun Wu Kenneth Kar‐Lung Yan Alex Yui Hui Desmond Chi‐Him Yiu Brian Bing‐Ying Wu David Cheung | 2014 | J Gastroenterol Hepatol2014，，1： | 1 |
| 7 | A macroscopic taxi model for passenger demand, taxi utilization and level of services显示文摘 | HAI YANG YAN WING LAU SZE CHUN WONG | 2000 | Transportation2000，，27： | 1 |
| 8 | Learning the “Whys”: Discovering design rationale using text mining — An algorithm perspective显示文摘 | Yan Liang Ying Liu Chun Kit Kwong Wing Bun Lee | 2011 | Computer-Aided Design2011，，10： | 1 |
| 9 | The destruction of the lower urinary tract by Ket- amine absue: a new syndrome 显示文摘 | Peggy Sau - Kwan Chu Wai - Kit Ma Simon Chun - Wing Wang | 2008 | BJU International2008，102，11： | 1 |
| 10 | Discovery of diagnostic serum biomarkers of gastric cancer using proteomics显示文摘 | Katie Wing‐keiLam Samuel Chun‐lapLo | 2008 | Prot Clin Appl2008，，2： | 1 |
| 11 | Effect of Kt/V on survival and clinical outcome in CAPD patients in a randomized prospective study 显示文摘 | Lo Wai kei Ho Yiu wing Li Chun sang | 2003 | Kidney Int2003，64，2： | 1 |
| 12 | Hepatic Actinomycosis Presenting as a Liver Tumour: Case Report and Literature Review显示文摘 | Alex T. Lai Chi Ming Lam Kelvin K. Ng Chun Yeung Wing Lau Ho Lap Tak Poon Irene O. Ng | 2004 | Asian Journal of Surgery2004，，4： | 1 |
| 13 | Laparoscopic Repair for Perforated Peptic Ulcer: A Randomized Controlled Trial显示文摘 | Wing T. Siu Heng T. Leong Bonita K. B. Law Chun H. Chau Anthony C. N. Li Kai H. Fung Yuk P. Tai Michael K. W. Li | 2002 | Annals of Surgery2002，，3： | 1 |
| 14 | A macroscopic taxi model for passenger demand, taxi utilization and level of services 显示文摘 | Hai Yang Yan Wing Lau Sze Chun Wong | 2000 | Transportation2000，，6： | 1 |
| 15 | A Geometrical Model For Kantian Intuition 显示文摘 | Wing - chun Wong | 1998 | Idealistic Studies28 ( 1 - 3 )1998，，： | 1 |
| 16 | Epstein-Barr virus-associated infectious mononucleosis in Chinese children显示文摘 | Chan Chun Wing Chiang | 2003 | Pediatr Infect Dis J2003，22，11： | 1 |
| 17 | Contributions of artificial lighting sources on light pollution in Hong Kong measured through a night sky brightness monitoring network 显示文摘 | Chun Shing Jason Pun Chu Wing So Wai Yan Leung Chung Fai Wong | 2014 | Journal of Quantitative Spectroscopy & Radiative Transfer2014，，139： | 1 |
| 18 | Antioxidant properties in vitro and total phenolic contents in methanol extracts from medicinal plants显示文摘 | LI Hua Bin WONG Chi Chun CHENG Ka Wing | 2008 | LWT-Food Science and Technology2008，41，3： | 1 |
| 19 | Severe Hypoglycemia Identifies Vulnerable Patients With Type 2 Diabetes at Risk for Premature Death and All-Site Cancer: The Hong Kong Diabetes Registry显示文摘 | Kong Alice PS Yang Xilin Luk Andrea Ma Ronald CW So Wing Yee Ozaki Risa Ting Rose Cheung Kitty Ho Chung Shun Chan Michael HM Chow Chun Chung Chan Juliana CN | 2014 | Diabetes Care2014，，4： | 1 |
| 20 | Laparoscopic Versus Open Appendectomy for Complicated Appendicitis显示文摘 | Kwok Kay Yau Wing Tai Siu Chun Ngai Tang George Pei Cheung Yang Michael Ka Wah Li | 2007 | Journal of the American College of Surgeons2007，，1： | 1 |
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