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| 1 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 2 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 3 | Excited - state properties of dioxorhenium(V) generation and reactivity of dioxorhenium(Ⅵ) 显示文摘 | Che C M Chung W C Lai T F | 1989 | Inorg Chem1989，28，： | 1 |
| 4 | Gelation of surimi by high hydrostatic pressure显示文摘 | Chung Y C Gebrehiwot A Farkas D F Morrissey M T | 1994 | J Food Sci1994，59，52： | 1 |
| 5 | Fuzzy kernel hyperball perceptron显示文摘 | Chung F L Wang S T Deng Z H | | 0，，01： | 1 |
| 6 | A heuristic me- thodology for order distribution in a demand driven collabora- tive supply chain显示文摘 | CHAN F T S CHUNG S H WADHWA S | 2004 | International Journal of Product Re- search2004，42，1： | 1 |
| 7 | Steel beams with large web openings of various shapes and sizes:an empirical design method using a generalized moment-shear interaction curve显示文摘 | Chung K F Liu T CH Ko A CH | 2003 | Journal of Constructional Steel Research2003，59，： | 1 |
| 8 | Steel beams with large web openings of various shapes and sizes:finite element investigation显示文摘 | Liu T CH Chung K F | 2003 | Journal of Constructional Steel Research2003，59，： | 1 |
| 9 | Experimental study on parameter choices in norm-r support vector regression machines with noisy input显示文摘 | Wang S T Zhu J G Chung F L | | 0，，03： | 1 |
| 10 | Adakites from continental collision zones: Melting of thickened lower crust beneath southern Tibet 显示文摘 | Chung S L Liu D Y Ji J Q Chu M F Lee H Y Wen D J Lo C H Lee T Y Qian Q Zhang Q | 2003 | Geology2003，31，11： | 1 |
| 11 | Seismic Behavior of Steel Beams and CFT Column Moment-resisting Connections with Floor Slabs 显示文摘 | CHENG C T CHAN C F CHUNG L L | 2007 | Journal of Constructional Steel Research2007，63，11： | 1 |
| 12 | FRSDE:Fast reduced set density estimator using minimal enclosing ball approximation显示文摘 | Deng Z H Chung F L Wang S T | | 0，，04： | 1 |
| 13 | Extravascu/ar lung water cor- relates multiorgan dysfunction syndrome and mortality in sepsis 显示文摘 | Chung F T Lin H C Kuo C H | 2010 | PLoS One2010，5，15： | 1 |
| 14 | Sub- cooled Boiling Incipience on a Highly Smooth Microheater 显示文摘 | Chen T Klausner J F Garimella S V Chung J N | 2006 | International Journal of Heat and Mass Transfer2006，49，： | 1 |
| 15 | Exploration of regeneration and reusability of human serum albumin as a stereoselective ligand for chiral separation in affinity ultrafiltration显示文摘 | Edwie F Li Yi Chung T S | 2010 | Journal of Membrane Science2010，362，10： | 1 |
| 16 | Development of greatburdock essence compounds显示文摘 | Wang C H Chung F Y Tsai T R e/ al | 2012 | Genomic Medicine Biomarkers and Health Sciences2012，4，1： | 1 |
| 17 | A novel image thresholding method based on Parzen windowestimate显示文摘 | Wang S T Chung F L Xiong F S | 2008 | Pattern Recognition2008，41，： | 1 |
| 18 | Toward accommodating realistic fuel chemistry in large-scale computations 显示文摘 | Lu T F Chung K L | 2009 | Combustion and Flame2009，35，： | 1 |
| 19 | Development and posi- tron annihilation spectroscopy (PAS) characterization of polyamide imide (PAI)-polyethersulfone(PES) based de-fect-free dual-layer hollow fiber membranes with an ultra- thin dense-selective layer for gas separation显示文摘 | Li F Y Li Y Chung T S | 2011 | Journal of Membrane Science2011，378，： | 1 |
| 20 | Cascaded centralized TSK fuzzy systems,Universal approximator and high interpretation显示文摘 | Wang S T Chung F L Shen H B | 2005 | Applied Soft Computing2005，5，： | 1 |
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