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| 1 | The Structure of Ore-controlling Strain and Stress Fields in the Shangzhuang Gold Deposit in Shandong Province,China显示文摘Shangzhuang 改变岩石的类型金牌矿石存款位于中间的片断并且在 Jiaodong 金省的西北的部分由 Wang'ershan 差错地区控制了,中国。在 Shangzhuang 存款的变丑进化,紧张的结构和压力地和它的控制矿石的效果在这份报纸被讨论。变丑进化主要经历了四个阶段,这被揭示:早可锻的变丑,第二 NE 惹人注目水平简单砍,第三 NE 惹人注目的压缩砍和最后的 NW 惹人注目的压缩。矿化作用发生在在的第三个阶段期间最大的主要压力逐渐地从 NE 的 transited 到 NW。 3-D 压力地的数字模拟证明在最大的主要压力是NE惹人注目的条件上,在差错地区的破裂发展被赞成,当时当最大的主要压力是NW惹人注目的时,差错地区是相对 extensional 和它对形成矿石的液体的流入和炮兵阵地合适。压缩砍紧张地被类型结构在矿化作用期间描绘,积极的花结构,等等。Orebodies 等距离地主要位于 dilatational 空格,它在不可分的有压缩性的情形是分布式的。并且在差错态度变化的地方, dilatational 空格被开发或砍联合系统发展。在全面压缩砍应力地里,紧张地在多重规模忍受自我类似,包括 orebody,矿石存款和 orefield。结构的自我类似在各种各样的规模在一样的规模和破裂的类似的形状包括破裂的 subequidistant 分发。由于特殊地质的结构,然而, orebodies 主要在 Shangzhuang 存款位于挂的墙它与在 Jiaodong 金省的大多数存款不同。在存款的控制矿石的压力和紧张地的分析为寻求的沉积物提供一个重要基础。 | DENG Jun WANG Qingfei YANG Liqiang ZHOU Lei GONG Qingjie YUAN Wanming XU Hao GUO Chunying LIU Xiangwei | 2008 | Acta Geologica Sinica(English Edition)2008，82，4： | 41 |
| 2 | Precise nanomedicine for intelligent therapy of cancer显示文摘Precise nanomedicine has been extensively explored for efficient cancer imaging and targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and clinical explorations. Here, we demonstrate the recent advances of intelligent cancer nanomedicine, and discuss the comprehensive understanding of their structure-function relationship for smart and efficient cancer nanomedicine including various imaging and therapeutic applications, as well as nanotoxicity. In particular, a few emerging strategies that have advanced cancer nanomedicine are also highlighted as the emerging focus such as tumor imprisonment, supramolecular chemotherapy, and DNA nanorobot. The challenge and outlook of some scientific and engineering issues are also discussed in future development. We wish to highlight these new progress of precise nanomedicine with the ultimate goal to inspire more successful explorations of intelligent nanoparticles for future clinical translations. | Huabing Chen Zhanjun Gu Hongwei An Chunying Chen Jie Chen Ran Cui Siqin Chen Weihai Chen Xuesi Chen Xiaoyuan Chen Zhuo Chen Baoquan Ding Qian Dong Qin Fan Ting Fu Dayong Hou Qiao Jiang Hengte Ke Xiqun Jiang Gang Liu Suping Li Tianyu Li Zhuang Liu Guangjun Nie Muhammad Ovais Daiwen Pang Nasha Qiu Youqing Shen Huayu Tian Chao Wang Hao Wang Ziqi Wang Huaping Xu Jiang-Fei Xu Xiangliang Yang Shuang Zhu Xianchuang Zheng Xianzheng Zhang Yanbing Zhao Weihong Tan Xi Zhang Yuliang Zhao | 2018 | Science China Chemistry2018，61，12： | 19 |
| 3 | Variations in net primary productivity and its relationships with warming climate in the permafrost zone of the Tibetan Plateau显示文摘温暖的气候触发的永久冻土降级处于土壤条件导致重要变化,并且进一步在植被上贡献明显的影响。然而,更不在网里关于差别被知道主要生产率(NPP ) 和在在不同植被类型和西藏的高原上的永久冻土地区的各种各样的类型之中的 NPP 和温暖的温度之间的关系。因而,遥远地察觉到陆地表面温度(LST ) 和从 MODIS 站台的 NPP 被用来调查植被 NPP 的反应到温暖气候,并且关联为学习区域被扩大规模。我们的结果从西方显示了 NPP 的著名增加到东方,并且显著地在西藏的高原的永久冻土地区从 2000 ~ 2010 与增加的 LST 一起增加了年度 NPP。同时,为各种各样的植被类型并且在有与温暖温度的关系的永久冻土地区的不同类型的增加的 NPP 被揭示。在连续永久冻土地区的 NPP 有最大的敏感到变化 LST,并且森林 NPP 介绍了最明显的反应。在在各种各样的规模的 NPP 和 LST 之间的积极关联显示了在西藏的高原的永久冻土地区在植被碳隐遁上温暖 LST 的提高的效果。鉴于到在这个高原上温暖温度的 NPP 的著名反应,进一步的遥感需要采用了在植被上揭示永久冻土降级和它的相关效果的地位。 | MAO Dehua LUO Ling WANG Zongming ZHANG Chunhua REN Chunying | 2015 | Journal of Geographical Sciences2015，25，8： | 18 |
| 4 | Remote Monitoring of Expansion of Aquaculture Ponds Along Coastal Region of the Yellow River Delta from 1983 to 2015显示文摘Aquaculture ponds are one of the fastest-growing land use types in valuable and fertile coastal areas and have caused serious environmental problems. Quantitative assessment of the extent, spatial distribution, and dynamics of aquaculture ponds is of utmost importance for sustainable economic development and scientific management of land and water resources in the coastal area. An object-oriented classification approach was applied to Landsat images acquired over three decades to investigate the long-term change of aquaculture ponds in the coastal region of the Yellow River Delta. The results indicated that the aquaculture ponds in the study area undergone a sharp expansion from 40.38 km^2 in 1983 to 1406.89 km^2 in 2015, and the fast expansion occurred during the period of 2010–2015 and 1990–2000. Natural wetlands, especially mudflat, and cropland were main land use types contributing to the increase of aquaculture ponds. The patches of aquaculture ponds were consequently prevalence in the north of the Yellow River Estuary and landscape metrics indicated an increase of the aquaculture ponds of the study area in the quantity and complexity. The expansion of aquaculture ponds inevitably had negative effects on the coastal environment, including loss of natural wetlands, water pollution and land subsidence, etc. The results from this study provide baseline data and valuable information for efficiently planning and managing aquaculture practices and for effectively implementing adequate regulations and protection measures. | REN Chunying WANG Zongming ZHANG Bai LI Lin CHEN Lin SONG Kaishan JIA Mingming | 2018 | Chinese Geographical Science2018，28，3： | 18 |
| 5 | Measurement and Correlation of Pressure Drop for Gas-Liquid Two-phase Flow in Rectangular Microchannels显示文摘The pressure drop of gas-liquid two-phase flow in microchannel is of fundamental importance in heat and mass transfer processes. In this work,the pressure drop of gas-liquid two-phase flow in horizontal rectangular cross-section microchannels was measured by a pressure differential transducer system. Water,ethanol and n-propanol were used as liquid phase to study the effects of capillary number on pressure drop;air was used as the gas phase. Four microchannels with various dimensions of 100 μm× 200 μm,100 μm× 400 μm,100 μm× 800 μm and 100 μm× 2000 μm(depth × width) were used for determining the influence of configuration on the pressure drop. Experimental results showed that in micro-scale,the capillary number also affected the pressure drop remarkably,and in spite of only one-fold difference in aspect ratio,the variation of pressure drop reached up to near three times under the same experimental conditions. Taking the effects of aspect ratio and surface tension into account,a modi-fied correlation for Chisholm parameter C in the Chisholm model was proposed for predicting the frictional multi-plier,and the predicted values by the proposed correlation showed a satisfactory agreement with experimental data. | MA Youguang JI Xiyan WANG Dongji FU Taotao ZHU Chunying | 2010 | Chinese Journal of Chemical Engineering2010，18，6： | 16 |
| 6 | Examining Forest Net Primary Productivity Dynamics and Driving Forces in Northeastern China During 1982–2010显示文摘Forest net primary productivity(NPP) is a key parameter for forest monitoring and management. In this study, monthly and annual forest NPP in the northeastern China from 1982 to 2010 were simulated by using Carnegie-Ames-Stanford Approach(CASA) model with normalized difference vegetation index(NDVI) sequences derived from Advanced Very High Resolution Radiometer(AVHRR) Global Inventory Modeling and Mapping Studies(GIMMS) and Terra Moderate Resolution Imaging Spectroradiometer(MODIS) products. To address the problem of data inconsistency between AVHRR and MODIS data, a per-pixel unary linear regression model based on least squares method was developed to derive the monthly NDVI sequences. Results suggest that estimated forest NPP has mean relative error of 18.97% compared to observed NPP from forest inventory. Forest NPP in the northeastern China increased significantly during the twenty-nine years. The results of seasonal dynamic show that more clear increasing trend of forest NPP occurred in spring and autumn. This study also examined the relationship between forest NPP and its driving forces including the climatic and anthropogenic factors. In spring and winter, temperature played the most pivotal role in forest NPP. In autumn, precipitation acted as the most important factor affecting forest NPP, while solar radiation played the most important role in the summer. Evaportranspiration had a close correlation with NPP for coniferous forest, mixed coniferous broadleaved forest, and broadleaved deciduous forest. Spatially, forest NPP in the Da Hinggan Mountains was more sensitive to climatic changes than in the other ecological functional regions. In addition to climatic change, the degradation and improvement of forests had important effects on forest NPP. Results in this study are helpful for understanding the regional carbon sequestration and can enrich the cases for the monitoring of vegetation during long time series. | MAO Dehua WANG Zongming WU Changshan SONG Kaishan REN Chunying | 2014 | Chinese Geographical Science2014，24，6： | 16 |
| 7 | Spatiotemporal Dynamics of Coastal Wetlands and Reclamation in the Yangtze Estuary During Past 50 Years(1960s–2015)显示文摘Reclamation is one of the fastest-growing land use type developed in coastal areas and has caused degradation and loss of coastal wetlands as well as serious environmental problems. This paper was aimed at monitoring the spatiotemporal patterns of coastal wetlands and reclamation in the Yangtze Estuary during the 1960s and 2015. Satellite images obtained from 1980 to 2015 and topography maps of the 1960 s were employed to extract changes of reclamation and coastal wetlands. Area-weight centroids were calculated to identify the movement trend of reclamation and coastal wetlands. The results show that from the 1960 s to 2015, the net area of natural wetlands declined by 574.3 km^2, while man-made wetlands and reclamation increased by 553.6 and 543.9 km^2, respectively. During the five study phases, the fastest areal change rate natural wetlands was –13.3 km^2/yr in the period of 1990–2000, and that of man-made areas was 24.7 km^2/yr in the same period, and the areal change rate of reclamation was 27.6 km^2/yr in the period of 2000–2010. Conversion of coastal wetlands mainly occurred in the Chongming Island, Changshu City and the east coast of Shanghai Municipality. Reclamation was common across coastal areas, and was mainly attributed to settlement and man-made wetlands in the Chongming Island, Lianyungang City and the east coast of Shanghai Municipality. Natural wetlands turned into farmlands and settlement, and man-made wetlands gained from reclamation of farmlands. The centroid of natural wetlands generally moved towards the sea, man-made wetlands expanded equally in all directions and inland, and the centroid of reclamation migrated toward Shanghai Municipality. Sea level rise, erosion-deposition changes, and reclamation activities together determine the dynamics of the Yangtze Estuary wetlands. However, reclamation activities for construction of ports, industries and aquaculture are the key causes for the dynamics. The results from this study on the dynamics of coastal wetlands and reclamation are valuable for local government to put forward sustainable land use and land development plans. | CHEN Lin REN Chunying ZHANG Bai LI Lin WANG Zongming SONG Kaishan | 2018 | Chinese Geographical Science2018，28，3： | 12 |
| 8 | Identification of genomic regions determining flower and pod numbers development in soybean (Glycine max L.)显示文摘Flower and pod numbers per plant are important agronomic traits underlying soybean yield. So far quantitative trait loci (QTL) detected for flower and pod-related traits have mainly focused on the final stage, and might therefore have ignored genetic effects expressed during a specific developmental stage. Here, dynamic expressions of QTL for flower and pod numbers were identified using 152 recom-binant inbred lines (RILs) and a linkage map of 306 markers. Wide genetic variation was found among RILs; 17 unconditional and 18 conditional QTL were detected for the two traits at different developmental stages over two years. Some QTL were detected only at one stage and others across two or more stages, indicating that soybean flower and pod numbers development may be governed by time-dependent gene expression. Three main QTL (qfn-Chr18-2, qfn-Chr20-1, and qfn-Chr19) were detected for flower number, and two main QTL (qpn-Chr11 and qpn-Chr20) were detected for pod number. The phenotypic variation explained by them ranged from 6.1% to 34.7%. The markers linked to these QTL could be used in marker-assisted selection for increasing soybean flower and pod numbers, with the ultimate aim of increasing soybean yield. Comparison of the QTL regions for flower and pod numbers traits with the related genes reported previously showed that seven and four related genes were located in the QTL regions of qfn-Chr11 and qfn-Chr19, respectively. These results provide a basis for fine mapping and cloning of flower and pod development-related genes. | Dan Zhang, Hao Cheng, Hui Wang, Hengyou Zhang, Chunying Liu, Deyue Yu National Center for Soybean Improvement, National Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing 210095, China | 2010 | Journal of Genetics and Genomics2010，37，8： | 11 |
| 9 | Land Use Changes in Northeast China Driven by Human Activities and Climatic Variation显示文摘Human-induced land use/cover change (LUCC) forms an important component of global environmental change. Therefore, it is important to study land use/cover and its change at local, regional and global scales. In this paper we conducted the study of land use change in Northeast China, one of the most important agricultural zones of the nation. From 1986 to 2000, according to the study results obtained from Landsat images, widespread changes in land use/cover took place in the study area. Grassland, marsh, water body and woodland decreased by 9864, 3973, 1367 and 10,052km2, respectively. By comparison, paddy field, dry farmland, and built-up land expanded by 7339, 17193 and 700km2, respectively. Those changes bore an interactive relationship with the environment, especially climate change. On the one hand, climate warming created a potential environment for grassland and marsh to be changed to farmland as more crops could thrive in the warmer climate, and for dry farmland to paddy field. On the other hand, the changed surface cover modified the local climate. Those changes, in turn, have adversely influenced the local environment by accelerating land degradation. In terms of socio-economic driving forces, population augment, regional economic development, and national and provincial policies were confirmed as main driving factors for land use change. | WANG Zongming LIU Zhiming SONG Kaishan ZHANG Bai ZHANG Sumei LIU Dianwei REN Chunying YANG Fei | 2009 | Chinese Geographical Science2009，19，3： | 10 |
| 10 | Modification on the tribological properties of ceramics lubricated by water using fullerenol as a lubricating additive显示文摘It is necessary to modify the running-in process for the application of ceramics using water as a lubricant in real conditions because ceramics sliding in water are characterized by a running-in period with severe friction and wear.Fullerenol,a kind of highly water-soluble nanoparticle,was synthesized and then used to ameliorate the tribological properties of Si 3 N 4 sliding against Al 2 O 3 in pure water.With the addition of fullerenol,the running-in period was shortened from 30 min to 100 s at a speed of 250 mm/s.The speed threshold above which ultralow friction can be obtained in a short time was expanded from 450 mm/s to 80 mm/s.Meanwhile,the load-carrying ability of water film was increased.The role of fullerenol was discussed based on observation of the wear scar by an optical interferometer and XPS characterization of the tribo-film on the wear track. | LIU YuHong WANG XiaoKang LIU PengXiao ZHENG JunPeng SHU ChunYing PAN GuoShun LUO JianBin | 2012 | Science China(Technological Sciences)2012，55，9： | 9 |
| 11 | Coordination-responsive drug release inside gold nanorod @ metal-organic framework core-shell nanostructures for near-infrared-induced synergistic chemo-photothermal therapy显示文摘 | Yantao Li Jun Jin Dawei Wang Jiawei Lv Ke Hou Yaling Liu Chunying Chen Zhiyong Tang | 2018 | Nano Research2018，11，6： | 7 |
| 12 | Smart CU1.75S nanocapsules with high and stable photothermal efficiency for NIR photo-triggered drug release显示文摘Thermosensitive 药交货系统(DDS ) 面对主要挑战,例如遥远、可重复的控制在 vivo 温度,尽管这些能增加药的治疗学的功效。处理这个问题,我们涂在红外线附近(NIR ) photothermal Cu 1.75 有 pH/thermos-sensitive 聚合物由的 S nanocrystals 在 situ 聚合。装载内容的 doxorubicine (纪录影片) 直到 40 wt.% ,与纪录影片在正常生理的条件下面正在被漏的不到 8.2 wt.%(pH = 7.4, 37 吗? | Sheng Huang Jing Liu Qian He Hongli Chen Jiabin Cui Suying Xu Yuliang Zhao Chunying Chen Leyu Wang | 2015 | Nano Research2015，8，12： | 7 |
| 13 | Bi2WO6 doped with rare earth ions:Preparation,characterization and photocatalytic activity under simulated solar irradiation显示文摘Rare-earth modification Bi2WO6 composites(RE/Bi2WO6)were studied by experimental performance and theory computation based on the different 4 f orbits of selected rare earth elements(La,Ce,Gd,and Yb).The prepared RE/Bi2WO6 was characterized by XRD,SEM/TEM,XPS,UV-vis DRS,and N2 adsorption to learn their physical-chemical properties.Azo dye Rhodamine B(RhB)was photodegraded as a target pollutant to investigate the photocatalytic activity of prepared RE/Bi2WO6 composites.The results of experiment and computation show that four rare earth elements with different electron configurations retain the phase and morphology of Bi2 WO6 and enhance the removal efficiency of RhB under simulated solar irradiation.The optimum doping contents are 0.01%,0.05%,0.05%and 0.01%for La-,Ce-,Gd-,and Yb-doped Bi2WO6,respectively.However,light rare earth La and Ce doped composites indicate some difference in visible light adso rption capacity and mineralization on RhB co mpared with heavy rare earth Gd and Yb doped composites.Both La/Bi2WO6 and Ce/Bi2 WO6 possess larger pore size and higher mineralization ability than Gd/Bi2 WO6 and Yb/Bi2WO6 under the same experimental conditions while Gd/Bi2WO6 and Yb/Bi2WO6 show stronger red shift to the visible light due to the more 4 f electrons.The hole oxidation plays a major role in the photodegradation of RhB by all RE/Bi2WO6. | Chunying Wang Chuantao Gu Ting Zeng Qingqing Zhang Xianping Luo | 2021 | Journal of Rare Earths2021，39，1： | 6 |
| 14 | ~1H nuclear magnetic resonance-based metabolomic study on efficacy of Qingrehuatan decoction against abundant phlegm-heat syndrome in young adults with essential hypertension显示文摘OBJECTIVE: To observe the influence of Qingrehuatan decoction(QRHT) on serum metabolic profile in young essential hypertension(YEH) patients with abundant phlegm-heat syndrome and provide a basis for treatment with the decoction.METHODS: Twelve male YEH patients were randomly selected and serum samples were collected for examination before and after 4 weeks of thetreatment with QRHT. Twelve healthy males were randomly selected and their serum samples were collected as a control. All serum samples were detected using metabolomic technology with1 H nuclear magnetic resonance. Differences in metabolites were studied by principal component analysis and partial least squares-discriminate analysis,which produced scores and loadings plots.RESULTS: After 4 weeks of treatment, serum substances could be distinguished between the YEH patients with abundant phlegm-heat syndrome and the control patients. The specific serum endogenous metabolites tended to improve after the treatment. QRHT can appropriately increase the levels of glucose, lactic acid, citric acid, high-density lipoprotein, phosphatidylcholine, glycerophosphate choline, hydroxybutyrate, alanine, and glutamate.QRHT could also decrease the levels of low-density lipoprotein/very low-density lipoprotein, lipids,N-acetyl glycoprotein, and O-acetyl glycoprotein.CONCLUSION: QRHT can effectively ameliorate metabolic disorders in YEH Patients with abundant phlegm- heat syndrome.1H NMR-based metabolomic technology can provide an objective basis for the treatment of YEH patients with abundant phlegm-heat syndrome using QRHT. | Feng Xuanchao Yang Zheng Chu Yuguang Du Bai Su Mei Li Yi Wang Yinghong Jiang Chunying Hu Yuanhui | 2015 | Journal of Traditional Chinese Medicine2015，35，1： | 6 |
| 15 | Impact of land use/land cover changes on ecosystem services in the Nenjiang River Basin, Northeast China显示文摘Introduction:The Nenjiang River Basin is an important foodstuff base and eco-environmental fragile area in Northeast China.With the rapid rise in human population,human-induced changes in land use/land cover form an important component of regional environment and ecosystem service change.At the local and regional level,the ecosystem service concept can act as a decision support tool for a stakeholder to reach sustainable land use management.However,the prevailing ecosystem service evaluation would produce a biggish warp when it is applied to concrete area.So,it is essential to evaluate ecosystem service change according to the local actuality.Method:According to 1:250,000 land use/land cover maps of China and the adjusted equivalent value per unit area of ecosystem services in the Nenjiang River Basin,we evaluated the ecosystem service change of the river basin from 1980 to 2005.Results:The forest and wetland,which are mainly located in the upstream mountainous area of the Nenjiang River Basin,were the two valuable land cover types,accounting for more than three quarters of the total ecosystem service value of the river basin.As for individual ecosystem service,besides the food production,all of the ecosystem service values declined from 1980 to 2005.The total decline of 2.43 billion USD was mainly due to the cultivation of grassland(14.34%of the area in 1980)and wetland(4.62%of the area in 1980)in the downstream plain.Conclusions:Due to the increase in population and the concomitant requirement of grain,the inconsistency between decision-making at the macro-level,and the objective of agricultural production at the micro-level,cultivated land was increased through zealous reclamation of grassland,marginal woodland,and even fallow land.Tremendous land use/land cover changes had caused great damages to the ecological environment such as land degradation and ecosystem service recession.So,the policies of the Grain for Green and Construction of Ecological Province projects should be well-implemented to optimize land use/land cover. | Zhiliang Wang Zongming Wang Bai Zhang Chunyan Lu Chunying Ren | 2015 | Ecological Processes2015，4，1： | 5 |
| 16 | Injectable collagen scaffold promotes swine myocardial infarction recovery by long-term local retention of transplanted human umbilical cord mesenchymal stem cells显示文摘Stem cell therapy is an attractive approach for recovery from myocardial infarction(MI)but faces the challenges of rapid diffusion and poor survival after transplantation.Here we developed an injectable collagen scaffold to promote the long-term retention of transplanted cells in chronic MI.Forty-five minipigs underwent left anterior descending artery(LAD)ligation and were equally divided into three groups 2 months later(collagen scaffold loading with human umbilical mesenchymal stem cell(hUMSC)group,hUMSC group,and placebo group(only phosphate-buffered saline(PBS)injection)).Immunofluorescence staining indicated that the retention of transplanted cells was promoted by the collagen scaffold.Echocardiography and cardiac magnetic resonance imaging(CMR)showed much higher left ventricular ejection fraction(LVEF)and lower infarct size percentage in the collagen/hUMSC group than in the hUMSC and placebo groups at 12 months after treatment.There were also higher densities of vWf-,α-sma-,and cTnT-positive cells in the infarct border zone in the collagen/cell group,as revealed by immunohistochemical analysis,suggesting better angiogenesis and more cardiomyocyte survival after MI.Thus,the injectable collagen scaffold was safe and effective on a large animal myocardial model,which is beneficial for constructing a favorable microenvironment for applying stem cells in clinical MI. | Qiang Wangn Xiaojun He Bin Wang Jun Pan Chunying Shi Jie Li Liudi Wang Yannan Zhao Jianwu Dai Dongjin Wang | 2021 | Science China(Life Sciences)2021，64，2： | 5 |
| 17 | In situ observation of C_(60)(C(COOH)_(2))_(2) interacting with living cells using fluorescence microscopy显示文摘The interactions between nanoparticles and living cells were investigated by an imaging technique of fluorescence microscopy. For this pur- pose, the C60 derivative C60(C(COOH)2)2, a thera- peutic agent for degeneration diseases of central nervous system, was synthesized, purified and characterized. Its interaction with the living cell and penetration of the cellular membrane were in situ studied using the real time imaging technique, and its potential cytotoxicity was also examined by flow cy- tometry. The results indicate that C60(C(COOH)2)2 can easily enter cells, and is mainly located in cytoplasm by fluorescein labeling. Furthermore, C60(C(COOH)2)2 can carry the molecule that cannot cross cellular membranes into cells, because fluo- rescein compound itself cannot enter the cell or ad- here to membrane. At concentrations ranging from 1×10?2 to 1×102 mg/L, C60(C(COOH)2)2 does not show any detectable cytotoxicity. | YE Chang CHEN Chunying CHEN Zhen MENG Huan XING Li JIANG Yaxin YUAN Hui XING Gengmei ZHAO Feng ZHAO Yuliang CHAI Zhifang FANG Xiaohong HAN Dong CHEN Long WANG Chen WEI Taotao | 2006 | Chinese Science Bulletin2006，51，9： | 4 |
| 18 | Uniqueness of the Gossypium mustelinum Genome Revealed by GISH and 45S rDNA FISH显示文摘Gossypium mustelinum ((广告) 4 ) 是在 Gossypium 的五 disomic 种之一。三 45S ribosomal DNA (rDNA ) loci 被检测在(广告) 4 作为探针与 Gossypium D 染色体种类的 genomic DNA (gDNA ) 作为探查,和三个更明亮的信号与 45S rDNA 被检测。尺寸和这些更明亮的信号的地点与作为探查与 45S rDNA 检测的那些一样,并且被称为 GISH -- 也不。他们之一是超级专业的,它说明了因为在染色体 3,和另外的二点关于它在中期的染色体的一个一半被定位的事实在染色体次要、定位 5 和 9 分别地。所有 GISH 也不位于一个亚染色体染色体,从另外的四 allopolyploid 棉花种分开。GISH -- 也没作为探查,然而并非 A 与 D 染色体种类被检测。极大地反常尺寸和地点(广告) 4 NORs 或 GISH 也不为列在后面的 45S rDNA 多样化(广告) 显示可能的机制 4 种形成。GISH 紧张和 GISH 的比较 -- 有 gDNA 的生产也不在 A 和 D 染色体表演之间探查更好的关系(广告) 4 与一个染色体。最短 G 的一个亚染色体的二个染色体。mustelinum 比 D 亚染色体染色体的最长的染色体短。因此,最长, tetraploid 棉花的 13 个染色体作为一个亚染色体正在被分类,当时更突然, 13 个染色体作为 D 亚染色体正在被分类在传统细胞发生并且 karyotype 分析不能是完全正确的。 | Qiong Wu Fang Liu Shaohui Li Guoli Song Chunying Wang Xiangdi Zhang Yuhong Wang David Stelly Kunbo Wang | 2013 | Journal of Integrative Plant Biology2013，55，7： | 4 |
| 19 | Estimating soil ammonium adsorption using pedotransfer functions in an irrigation district of the North China Plain显示文摘Extensive use of chemical fertilizers in agriculture can induce high concentration of ammonium nitrogen(NH4^(+)_(-)N) in soil. Desorption and leaching of NH4^(+)_(-)N has led to pollution of natural waters. The adsorption of NH4^(+)_(-)N in soil plays an important role in the fate of the NH4^(+)_(-)N. Understanding the adsorption characteristics of NH4^(+)_(-)N is necessary to ascertain and predict its fate in the soil-water environment, and pedotransfer functions(PTFs) could be a convenient method for quantification of the adsorption parameters. Ammonium nitrogen adsorption capacity, isotherms, and their influencing factors were investigated for various soils in an irrigation district of the North China Plain. Fourteen agricultural soils with three types of texture(silt, silty loam, and sandy loam) were collected from topsoil to perform batch experiments. Silt and silty loam soils had higher NH4^(+)_(-)N adsorption capacity than sandy loam soils.Clay and silt contents significantly affected the adsorption capacity of NH4^(+)_(-)N in the different soils. The adsorption isotherms of NH4^(+)_(-)N in the 14 soils fit well using the Freundlich, Langmuir, and Temkin models. The models’ adsorption parameters were significantly related to soil properties including clay,silt, and organic carbon contents and Fe^(2+) and Fe^(3+) ion concentrations in the groundwater. The PTFs that relate soil and groundwater properties to soil NH4^(+)_(-)N adsorption isotherms were derived using multiple regressions where the coefficients were predicted using the Bayesian method. The PTFs of the three adsorption isotherm models were successfully verified and could be useful tools to help predict NH4^(+)_(-)N adsorption at a regional scale in irrigation districts. | Chunying WANG Defeng WU Xiaomin MAO Jingming HOU Lei WANG Yuping HAN | 2021 | Pedosphere2021，31，1： | 4 |
| 20 | Nano-bio interactions: the implication of size-dependent biological effects of nanomaterials显示文摘Due to their many advantageous properties,nanomaterials(NMs)have been utilized in diverse consumer goods,industrial products,and for therapeutic purposes.This situation leads to a constant risk of exposure and uptake by the human body,which are highly dependent on nanomaterial size.Consequently,an improved understanding of the interactions between different sizes of nanomaterials and biological systems is needed to design safer and more clinically relevant nano systems.We discuss the sizedependent effects of nanomaterials in living organisms.Upon entry into biological systems,nanomaterials can translocate biological barriers,distribute to various tissues and elicit different toxic effects on organs,based on their size and location.The association of nanomaterial size with physiological structures within organs determines the site of accumulation of nanoparticles.In general,nanomaterials smaller than 20 nm tend to accumulate in the kidney while nanomaterials between 20 and 100 nm preferentially deposit in the liver.After accumulating in organs,nanomaterials can induce inflammation,damage structural integrity and ultimately result in organ dysfunction,which helps better understand the size-dependent dynamic processes and toxicity of nanomaterials in organisms.The enhanced permeability and retention effect of nanomaterials and the utility of this phenomenon in tumor therapy are also highlighted. | Xiaoyu Wang Xuejing Cui Yuliang Zhao Chunying Chen | 2020 | Science China(Life Sciences)2020，63，8： | 4 |
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