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| 1 | Measuring Conflict Functions in Generalized Power Space显示文摘One of the most important open issues is that the classical conflict coefficient in D-S evidence theory (DST) cannot correctly determine the conflict degree between two pieces of evidence. This drawback greatly limits the use of DST in real application systems. Early researches mainly focused on the improvement of Dempster’s rule of combination (DRC). However, the current research shows it is very important to define new conflict coefficients to determine the conflict degree between two or more pieces of evidence. The evidential sources of information are considered in this work and the definition of a conflict measure function (CMF) is proposed for selecting some useful CMFs in the next fusion work when sources are available at each instant. Firstly, the definition and theorems of CMF are put forward. Secondly, some typical CMFs are extended and then new CMFs are put forward. Finally, experiments illustrate that the CMF based on Jousselme and its similar ones are the best suited ones. | HU Lifang GUAN Xin DENG Yong HAN Deqiang HE You | 2011 | Chinese Journal of Aeronautics2011，24，1： | 11 |
| 2 | A study of electron-shuttle mechanism in Klebsiella pneumoniae based-microbial fuel cells显示文摘In microbial fuel cell (MFC), the rate of electron transfer to anode electrode is a key intrinsic limiting factor on the power output of MFCs. Using Klebsiella pneumoniae (K. pneumoniae) strain L17 as biocatalyst, we studied the mechanism of electron shuttle via self-producing mediator in a cubic air-chamber MFC. To eliminate the influence of biofilm mechanism, the anode electrode was coated with microfiltration membrane (0.22 μm). Data showed that the microfiltration membrane coated and uncoated MFCs achieved the maximum voltage outputs of 316.2 and 426.2 mV after 270 and 120 h, respectively. When the medium was replaced in MFCs that had the highest power generation, the power output dropped by 62.1% and 8.8%, and required 120 and 48 h to resume the original level in the coated and uncoated MFCs, respectively. The results suggested an electron-shuttle mechanism rather than biofilm mechanism was responsible for electricity generation in the membrane coated MFC. Cyclic voltammetric measurements demonstrated the presence of an electrochemical active compound produced by K. pneumoniae strain L17, which was identified to be 2,6-di-tert-butyl-p-benzoquinon (2,6-DTBBQ) by GC-MS. 2,6-DTBBQ, as a recyclable electron shuttle, could transfer electrons between K. pneumoniae L17 and the anode electrode. | DENG LiFang LI FangBai ZHOU ShunGui HUANG DeYin NI JinRen | 2010 | Chinese Science Bulletin2010，55，1： | 9 |
| 3 | New method for measuring the degree of conflict among general basic probability assignments显示文摘There is doubt about Dempster's rule of combination because of counter-intuitive results when dealing with conflict information in intelligent reasoning.Therefore,many modified combination rules have been presented in the literature on multi-source information fusion and reasoning with uncertainty.However,the issue of identifying conflict among evidence has been ignored.A new parameter measuring conflict evidence called the conflict distance parameter is defined to determine whether there are conflicts in evidence based on the analysis of existing conflict parameters.At the same time,a decisive rule,which a reasonable conflict measure function should satisfy,is put forward.Finally,an analysis of two typical counter-intuitive situations is given,showing that the new parameter can not only satisfy the decisive rule,but can also attain the same effect as a two-dimensional measure when deciding whether to use the Dempster's rule of combination,and can exceed its effect when deciding whether to use Dezert-Smarandache theory. | HE You HU LiFang GUAN Xin DENG Yong HAN DeQiang | 2012 | Science China(Information Sciences)2012，55，2： | 7 |
| 4 | Cross-sectional survey of the relationship of symptomatology, disability and family burden among patients with schizophrenia in Sichuan, China显示文摘 | Zhuoqiu ZHANG Hong DENG Ying CHEN Shuiying LI Qian ZHOU Hua LAI Lifang LIU Ling LIU wenwu SHEN | 2014 | 上海精神医学2014，26，1： | 6 |
| 5 | Spatial Analysis of Commuting Mode Choice in Guangzhou, China显示文摘Metropolitan cities in China are commonly confronted with unresolved traffic congestion issues, primarily due to rapidly increasing traffic demand. Group disparity between commuting mode choice and its spatial distribution on road networks has enabled us to examine the factors that give rise to the discrepancies and the fundamental spatial causes of traffic congestion. In recent years, micro-perspective, individual, and behavior-based spatial analysis have mushroomed and been facilitated with effective tools such as temporal geographic information systems (T-GIS). It is difficult to study the interrelations between transport and space on the basis of commuting mode choice since the mode choice data are invisible in a specific space such as a particular road network. Therefore, in the field of transport, the classical origin destination (OD) four-stage model (FSM) is usually employed to calculate data when studying commuting mode choice. Based on the relative principles of T-GIS and the platform of ArcGIS, this paper considers Guangzhou as a case study and develops a spatio-temporal tool to examine the daily activities of residents. Meanwhile, the traffic volume distribution in rush hours, which was analyzed according to commuting modes and how they were reflected in the road network, was scrutinized with data extracted from travel diaries. Moreover, efforts were made to explain the relationship between traffic demand and urban spatial structure. Based on the investigation, this research indicates that traffic volumes in divergent groups and on the road networks is driven by: 1) the socio-economic characteristics of travelers; 2) a jobs-housing imbalance under suburbanization; 3) differences in the spatial supply of transport modes; 4) the remains of the Danwei (work unit) system and market development in China; and 5) the transition of urban spatial structure and other factors. | ZHOU Suhong DENG Lifang HUANG Meiyu | 2013 | Chinese Geographical Science2013，23，3： | 4 |
| 6 | A New Probabilistic Transformation in Generalized Power Space显示文摘The mapping from the belief to the probability domain is a controversial issue, whose original purpose is to make (hard) decision, but for contrariwise to erroneous widespread idea/claim, this is not the only interest for using such mappings nowadays. Actually the probabilistic transformations of belief mass assignments are very useful in modern multitarget multisensor tracking systems where one deals with soft decisions, especially when precise belief structures are not always available due to the existence of uncertainty in human being’s subjective judgments. Therefore, a new probabilistic transformation of interval-valued belief structure is put forward in the generalized power space, in order to build a subjective probability measure from any basic belief assignment defined on any model of the frame of discernment. Several examples are given to show how the new transformation works and we compare it to the main existing transformations proposed in the literature so far. Results are provided to illustrate the rationality and efficiency of this new proposed method making the decision problem simpler. | HU Lifang HE You GUAN Xin DENG Yong HAN Deqiang | 2011 | Chinese Journal of Aeronautics2011，24，4： | 4 |
| 7 | Interaction Between Variations in Dopamine D2 and Serotonin 2A Receptor is Associated with Short-Term Response to Antipsychotics in Schizophrenia显示文摘Dear Editor,Schizophrenia is a chronic and debilitating brain disorder,which has a strong genetic component with heritability ranging from 66%to 85%[1,2].Currently,antipsychotic drugs remain the most effective treatment for the psychotic symptoms of schizophrenia[3].Because of the severe sideeffects of first-generation antipsychotics(FGAs),secondgeneration antipsychotics(SGAs)have become more widely used in the treatment of schizophrenia. | Liansheng Zhao Huijuan Wang Yamin Zhang Jinxue Wei Peiyan Ni Hongyan Ren Gang Li Qiang Wang Gavin P Reynolds Weihua Yue Wei Deng Hao Yan Liwen Tan Qi Chen Guigang Yang Tianlan Lu Lifang Wang Fuquan Zhang Jianli Yang Keqing Li Luxian Lv Qingrong Tan Yinfei Li Hua Yu Hongyan Zhang Xin Ma Fude Yang Lingjiang Li Chuanyue Wang Huiyao Wang Xiaojing Li Wanjun Guo Xun Hu Yang Tian Xiaohong Ma Jeremy Coid Dai Zhang Chao Chen Tao Li Chinese Antipsychotics Pharmacogenomics Consortium | 2019 | Neuroscience Bulletin2019，35，6： | 3 |
| 8 | Testing the role of genetic variation of the MC4R gene in Chinese population in antipsychotic-induced metabolic disturbance显示文摘Antipsychotic-induced metabolic disturbance(AIMD) is a common adverse effect of antipsychotics with genetics partly underpinning variation in susceptibility among schizophrenia patients. Melanocortin4 receptor(MC4 R) gene, one of the candidate genes for AIMD, has been under-studied in the Chinese patients. We conducted a pharmacogenetic study in a large cohort of Chinese patients with schizophrenia. In this study, we investigated the genetic variation of MC4 R in Chinese population by genotyping two SNPs(rs489693 and rs17782313) in 1,991 Chinese patients and examined association of these variants with the metabolic effects that were often observed to be related to AIMD. Metabolic measures, including body mass index(BMI), waist circumference(WC), glucose, triglyceride, high-density lipoprotein(HDL), and low-density lipoprotein(LDL) levels were assessed at baseline and after 6-week antipsychotic treatment. We found that interaction of SNP×medication status(drug-na?ve/medicated) was significantly associated with BMI, WC, and HDL change %, respectively. Both SNPs were significantly associated with baseline BMI and WC in the medicated group. Moderate association of rs489693 with WC, Triglyceride, and HDL change % were observed in the whole sample. In the drug-na?ve group, we found recessive effects of rs489693 on BMI gain more than 7%, WC and Triglyceride change %, with AA incurring more metabolic adverse effects. In conclusion, the association between rs489693 and the metabolic measures is ubiquitous but moderate. Rs17782313 is less involved in AIMD. Two SNPs confer risk of AIMD to patients treated with different antipsychotics in a similar way. | Yamin Zhang Hongyan Ren Qiang Wang Wei Deng Weihua Yue Hao Yan Liwen Tan Qi Chen Guigang Yang Tianlan Lu Lifang Wang Fuquan Zhang Jianli Yang Keqing Li Luxian Lv Qingrong Tan Hongyan Zhang Xin Ma Fude Yang Lingjiang Li Chuanyue Wang Dai Zhang Liansheng Zhao Huiyao Wang Xiaojing Li Wanjun Guo Xun Hu Yang Tian Xiaohong Ma Tao Li Chinese Antipsychotics Pharmacogenomics Consortium | 2019 | Science China(Life Sciences)2019，62，4： | 3 |
| 9 | Isolation and characterization of liver epithelial progenitor cells from normal adult rhesus monkeys (Macaca mulatta)显示文摘 | Lifang Jin Shaohui Ji Xianghui Tang Xiangyu Guo Yongqing Lu Hongwei Chen Hongkui Deng Qi Zhou Weizhi Ji | 2009 | Cell Research2009，19，2： | 2 |
| 10 | New conflict representation model in generalized power space显示文摘The study on alternative combination rules in Dempster-Shafer theory (DST) when evidences are in conflict has emerged again recently as an interesting topic, especially in data/information fusion applications. The earlier researches have mainly focused on investigating the alternative which would be appropriate for the conflicting situation, under the assumption that a conflict is identified. However, the current research shows that not only the combination rule but also the classical conflict coefficient in DST are not correct to determine the conflict degree between two pieces of evidences. Most existing methods of measuring conflict do not consider the open world situation, whose frame of discernment is incomplete. To solve this problem, a new conflict representation model to determine the conflict degree between evidences is proposed in the generalized power space, which contains two parameters: the conflict distance and the conflict coefficient of inconsistent evidences. This paper argues that only when the conflict measure value in the new representation model is high, it is safe to say the evidences are in conflict. Experiments illustrate the efficiency of the proposed conflict representation model. | You He Lifang Hu Xin Guan Deqiang Han Yong Deng | 2012 | Journal of Systems Engineering and Electronics2012，23，1： | 2 |
| 11 | Immunomodulatory activity and partial characterisation of polysaccharides from Momordica charantia显示文摘 | DENG Yuanyuan YI Yang ZHANG Lifang | 2014 | Molecules2014，19，13： | 1 |
| 12 | In the spring,aloe vera gel in the treatment of recurrent oral ulcer clinical curative effect observation of显示文摘 | Deng Xuelian Liu Lifang Fu Zhong | | 0，，： | 1 |
| 13 | New probabilistic transformation of imprecise belief structure显示文摘The case when the source of information provides precise belief function/mass,within the generalized power space,has been studied by many people.However,in many decision situa-tions,the precise belief structure is not always available.In this case,an interval-valued belief degree rather than a precise one may be provided.So,the probabilistic transformation of impre-cise belief function/mass in the generalized power space including Dezert-Smarandache(DSm) model from scalar transformation to sub-unitary interval transformation and,more generally,to any set of sub-unitary interval transformation is provided.Different from the existing probabilistic transformation algorithms that redistribute an ignorance mass to the singletons involved in that ignorance pro-portionally with respect to the precise belief function or probability function of singleton,the new algorithm provides an optimization idea to transform any type of imprecise belief assignment which may be represented by the union of several sub-unitary(half-) open intervals,(half-) closed intervals and/or sets of points belonging to [0,1].Numerical examples are provided to illustrate the detailed implementation process of the new probabilistic transformation approach as well as its validity and wide applicability. | Lifang Hu You He Xin Guan Deqiang Han Yong Deng | 2011 | Journal of Systems Engineering and Electronics2011，22，5： | 1 |
| 14 | Design and experimental verification of a monolithic complete-light modulator based on birefringent materials显示文摘This paper presents a method to design a monolithic complete-light modulator(MCLM) that fully controls the amplitude, phase, and polarization of incident light. The MCLM is made of birefringent materials that provide different refractive indices to orthogonal eigen-polarizations, the ordinary o and extraordinary e states. We propose an optimization method to calculate the two relief depth distributions for the two eigen-polarizations. Also, a merging algorithm is proposed to combine the two relief depth distributions into one. The corresponding simulations were carried out in this work and the desired light distribution, including information on amplitude,phase, and four polarization states, was obtained when a laser beam passed through a 16-depth-level microstructure whose feature size is 8 μm. The structure was fabricated by common photolithography. An experimental optical system was also set up to test the optical effects and performances of the MCLM. The experimental performance of the MCLM agrees with the simulation results, which verifies the validity of the algorithms we propose in this paper. | YINGFEI PANG AXIU CAO JIAZHOU WANG HUI PANG WEI YAN XIANGDONG WU LIFANG SHI QILING DENG | 2019 | Photonics Research2019，7，8： | 0 |
| 15 | Prediction of CO_(2) solubility in deep eutectic solvents using random forest model based on COSMO-RS-derived descriptors显示文摘This work presents the development of molecular-based mathematical model for the prediction of CO_(2) solubility in deep eutectic solvents(DESs).First,a comprehensive database containing 1011 CO_(2) solubility data in various DESs at different temperatures and pressures is established,and the COSMO-RS-derived descriptors of involved hydrogen bond acceptors and hydrogen bond donors of DESs are calculated.Afterwards,the efficiency of the input variables,i.e.,temperature,pressure,COSMO-RS-derived descriptors of HBA and HBD as well as their molar ratio,is explored by a qualitative analysis of CO_(2) solubility in DESs using a simple multiple linear regression model.A machine learning method namely random forest is then employed to develop more accurate nonlinear quantitative structure-property relationship(QSPR)model.Combining the QSPR validation and comparisons with literature-reported models(i.e.,COSMO-RS model,traditional thermodynamic models and equations of state methods),the developed QSPR model with COSMO-RS-derived parameters as molecular descriptors is suggested to be able to give reliable predictions of CO_(2) solubility in DESs and could be used as a useful tool in selecting DESs for CO_(2) capture processes. | Jingwen Wang Zhen Song Lifang Chen Tao Xu Liyuan Deng Zhiwen Qi | 2021 | Green Chemical Engineering2021，2，4： | 0 |
| 16 | Preparation of Double-sided Nanostructure Based on Soft-nanoimprinting Lithography显示文摘Double-sided nanostructure has more excellent properties in high efficiency,high yield,and high capability devices,which becomes the attention spots in nanofabrication technology.We proposed a very simple method to fabricate the double-sided nanostructure on polymer elastic substrate.By using twice soft-nanoimprinting process,the same or different nanostructures array was fabricated onto the elastomeric slab substrate.In this paper,we fabricated double-sided nanopillars array with different diameters of 200nm and 350nm.In order to expand the applications field in optical and electronic devices,metal layer could be deposited onto the substrate before imprinting nanostructure. | Man Zhang Qiling Deng Hui Pang Lifang Shi Axiu Cao | 2018 | Journal of Microelectronic Manufacturing2018，1，2： | 0 |
| 17 | Prolonged control of insulin-dependent diabetes via intramuscular expression of plasmid-encoded single-strand insulin analogue显示文摘Daily insulin injection is necessary for the treatment of the insulin-dependent diabetes. However, the process is painful and inconvenient. Accordingly, we have made exploratory efforts to establish an alternative method for continuous insulin supply via intramuscular injection of a designed plasmid encoding the single-strand insulin analogue (SIA), which provides safe, effective and prolonged control of insulin-dependent diabetes. To generate a SIA, a short flexible peptide was alternatively introduced into the natural proinsulin to replace its original long and rigid C-peptide. Then, the synthetic promoter SP301 was used to drive potent and specific expression of SIA in skeletal muscle cells. By combining the Pluronic L64 and low-voltage electropulse (L/E), the specialized gene delivery technique was applied to efficiently transfer the constructed plasmid into skeletal muscle cells via intramuscular injection. Through these efforts, a plasmid-based intramuscular gene expression system was established and improved, making it applicable for gene therapy. The plasmid-expressed SIA showed biological functions that were similar to that of natural insulin. A single L/E-pSP301-SIA administration provided sustained SIA expression in vivo for about 1.5 months. In addition, the diabetic mice treated with L/E-pSP301-SIA were much healthier than those with other treatments. This plasmid-based system was safe for the treatment of diabetes and did not cause immune responses or pathological damage. The results confirmed that, in a mouse model, long-term positive effects were achieved by a single intramuscular L/E-pSP301-SIA injection, which consequently provided reliable experimental basis for its clinical application for the treatment of diabetes mellitus with promising prospects. | Lu Deng Ping Yang Caixia Li Lifang Xie Wanling Lu Yanhan Zhang Ming Liu Gang Wang | 2023 | Genes & Diseases2023，10，3： | 0 |
| 18 | Li^(+)-ion bound crown ether functionalization enables dual promotion of dynamics and thermodynamics for ambient ammonia synthesis显示文摘Electrosynthesis of ammonia from the reduction of nitrogen is still confronted with the limited supply of gas reactant in dynamics as well as high activation barrier in thermodynamics.Unfortunately,despite tremendous efforts devoted to electrocatalysts themselves,they still fail to tackle the above two challenges simultaneously.Herein,we employ a heterogeneous catalyst adlayer-composed of crown ethers associated with Li^(+)ions-to achieve the dual promotion of dynamics and thermodynamics for ambient ammonia synthesis.Dynamically,the bound Li^(+)ions interact with the strong quadrupole moment of nitrogen,and trigger considerable reactant flux toward the catalyst.Thermodynamically,Li^(+)associated with the oxygen of crown ether achieves a higher density of states at the Fermi level for the catalyst,enabling effortless electron transfer from the catalysts to nitrogen and thus greatly reducing the activation barrier.As expected,the proof-of-concept system achieves an ammonia yield rate of 168.5μg h^(-1)mg^(-1)and a Faradaic efficiency of 75.3%at-0.3 V vs.RHE.This system-level approach opens up pathways for tackling the two key challenges that have limited the field of ammonia synthesis. | Qiyang Cheng Sisi Liu Mengfan Wang Lifang Zhang Yanzheng He Jiajie Ni Jingru Zhang Chengwei Deng Yi Sun Tao Qian Chenglin Yan | 2023 | Journal of Energy Chemistry2023，，10： | 0 |
| 19 | Plasma Extracellular Vesicle MicroRNA Analysis of Alzheimer’s Disease Reveals Dysfunction of a Neural Correlation Network显示文摘Small extracellular vesicle(sEV)is an emerging source of potential biomarkers of Alzheimer's disease(AD),but the role of microRNAs(miRNAs)in sEV is not well understood.In this study,we conducted a comprehensive analysis of sEV-derived miRNAs in AD using small RNA sequencing and coexpression network analysis.We examined a total of 158 samples,including 48 from AD patients,48 from patients with mild cognitive impairment(MCI),and 62 from healthy controls.We identified an miRNA network module(M1)that was strongly linked to neural function and showed the strongest association with AD diagnosis and cognitive impairment.The expression of miRNAs in the module was decreased in both AD and MCI patients compared to controls.Conservation analysis revealed that M1 was highly preserved in the healthy control group but dysfunctional in the AD and MCI groups,suggesting that changes in the expression of miRNAs in this module may be an early response to cognitive decline prior to the appearance of AD pathology.We further validated the expression levels of the hub miRNAs in M1 in an independent population.The functional enrichment analysis showed that 4 hub miRNAs might interact with a GDF11-centered network and play a critical role in the neuropathology of AD.In summary,our study provides new insights into the role of sEV-derived miRNAs in AD and suggests that M1 miRNAs may serve as potential biomarkers for the early diagnosis and monitoring of AD. | Yuzhe Sun Zhen Hefu Benchao Li Wang Lifang Song Zhijie Li Zhou Yan Deng Liu Zhili Jiahong Ding Tao Li Wenwei Zhang Nie Chao Shuang Rong | 2023 | Research2023，，4： | 0 |
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