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| 1 | 体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。 | 刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B | 2020 | 中华高血压杂志2020，28，3： | 22 |
| 2 | Failure of hepatocyte marker-expressing hematopoietic progenitor cells to efficiently convert into hepatocytes in vitro显示文摘 | Lian G Wang C Teng C Zhang C Du L Zhong Q Miao C Ding M Deng H | 2006 | 中国生物学文摘2006，20，5： | 11 |
| 3 | Investigation of the thermal mechanical properties of a plasmasprayed nanostructured zirconia coating显示文摘 | Chen H Zhou X M Ding C X | 2003 | Journal of the European Ceramics Society2003，23，： | 1 |
| 4 | Study on microstructures and mechanical properties of B510L steel by TMCP显示文摘 | LI L YANG C Z DING H | 2005 | Materials Science Forum2005，47，： | 1 |
| 5 | Nucleic acid biosensor for detection of hepatitis B virus using 2,9-dimethyl- 1,10-phenanthroline copper complex as electrochemical indicator显示文摘 | Li X Ju H Ding C | 2007 | Analytica ChimicaActa2007，582，1： | 1 |
| 6 | 显示文摘 | Ding S J Ju C P Lin J H C | 2000 | Journal of Materials Science:Materials in Medicine2000，11，1： | 1 |
| 7 | Temperature-Dependent Photoluminescence of ZnO Nanorods Prepared by a Simple Solution Route显示文摘 | Lv Y Z Zhang Y H Li C P Ren L R Guo L Xu H B Ding L Yang C L Ge W K and Yang S H | 2007 | Luminescence2007，，： | 1 |
| 8 | Synthesis and characterization of chitosan-poly(acrylic acid) nanoparticles显示文摘 | Hu Y Jiang X Q Ding Y Ge H X Yuan Y Y Yang C Z | 2002 | Biomaterials2002，23，： | 1 |
| 9 | Celecoxib derivatives induce apoptosis via the disruption of mitochondrial membrane potential and activation of caspase 9显示文摘 | Ding H Han C Zhu J | 2005 | Int J Cancer2005，113，5： | 1 |
| 10 | The Differential Expres- sion of Hepatic Genes Between Prelaying and Laying Geese显示文摘 | S T Ding C F Yen P H Wang | 2007 | Poultry Science2007，86，： | 1 |
| 11 | Numerical Simulation and Analysis of Tapered Interference Fit of Atomizer Disk 显示文摘 | Lin S H Li C J Ding J P | 2012 | AppIied Mechanics and Materials2012，201，： | 1 |
| 12 | 显示文摘 | Zhang H L Ding J C’Qiu Y L | 2012 | Bioresourse Technolo-gy2012，112，： | 1 |
| 13 | Feature selection based on mutual information:Criteria of max-dependency,max-relevance,and min-redundancy显示文摘 | Peng H Long F Ding C | | 0，，08： | 1 |
| 14 | Magnetically engineered Cd-free quan- tum dots as dual-modality probes for fluorescence/magnetic resonance im- aging of tumors 显示文摘 | DING K JING L H LIU C Y | 2014 | Biomaterials2014，35，： | 1 |
| 15 | Expression pattern genomic struc- ture, and promoter analysis of the gene encoding stilbene synthase from Chinese wild Vitis pseudoreticulata显示文摘 | XU W R YU Y H ZHOU Q DING J H DAI L M XIE X Q XU Y ZHANG C H WANG Y J | 2011 | Journal of Experimen- tal Botany2011，62，8： | 1 |
| 16 | A level set method for imagesegmentation in the presence of intensity inhomogeneitieswith application to MRI显示文摘 | Li C M Huang R Ding Z H | 2011 | IEEE Transactions on Image Processing2011，20，7： | 1 |
| 17 | Feature selection based on mutual information, Criteria of max-dependency, max-relevance, and min-redundancy显示文摘 | PENG H C LONG F H DING C | 2005 | IEEE Transactions on Pattern Analysis and Machine Intelligence2005，8，27： | 1 |
| 18 | Analysis of nonylphenol polyethoxycarboxylates and their related metabolites by on-line derivatization and ion-trap gas chromatography- mass spectrometry 显示文摘 | DING W H CHEN C T | 1999 | Journal of Chromatography A1999，862，1： | 1 |
| 19 | Climate change due to greenhouse effects in China as simulated by a regional climate model显示文摘 | Gao X J Zhao Z C Ding Y H | 2001 | Adv Atmos Sci2001，18，6： | 1 |
| 20 | Minimum redundancy feature selection from microarray gene expression data显示文摘 | DING C PENG H | 2005 | Journal of Bioinformatics and Computational Biology2005，3，2： | 1 |
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