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| 1 | Cropland redistribution to marginal lands undermines environmental sustainability显示文摘Cropland redistribution to marginal land has been reported worldwide;however,the resulting impacts on environmental sustainability have not been investigated sufficiently.Here we investigated the environmental impacts of cropland redistribution in China.As a result of urbanization-induced loss of high-quality croplands in south China(~8.5 t ha^(-1)),croplands expanded to marginal lands in northeast(~4.5 t ha^(-1)) and northwest China(~2.9 t ha^(-1)) during 1990-2015 to pursue food security.However,the reclamation in these low-yield and ecologically vulnerable zones considerably undermined local environmental sustainability,for example increasing wind erosion(+3.47%),irrigation water consumption(+34.42%),fertilizer use(+20.02%) and decreasing natural habitats(-3.11%).Forecasts show that further reclamation in marginal lands per current policies would exacerbate environmental costs by 2050.The future cropland security risk will be remarkably intensified because of the conflict between food production and environmental sustainability.Our research suggests that globally emerging reclamation of marginal lands should be restricted and crop yield boost should be encouraged for both food security and environmental benefits. | Wenhui Kuang Jiyuan Liu Hanqin Tian Hao Shi Jinwei Dong Changqing Song Xiaoyong Li Guoming Du Yali Hou Dengsheng Lu Wenfeng Chi Tao Pan Shuwen Zhang Rafiq Hamdi Zherui Yin Huimin Yan Changzhen Yan Shixin Wu Rendong Li Jiuchun Yang Yinyin Dou Wenbin Wu Liqiao Liang Bao Xiang Shiqi Yang | 2022 | National Science Review2022，9，1： | 13 |
| 2 | Continuous land cover change monitoring in the remote sensing big data era显示文摘Since the late 20th century,global change issues have attracted lots of attention.As a key component of global changes,land cover and land use information has been increasingly important for improved understanding of global environmental changes and feedbacks between social and environmental systems(Verburg et al.,2015).A set of national and global scale land cover/use products with higher spatial and temporal resolutions have been developed to fill this gap.In China,existing efforts include China’s | DONG JinWei KUANG WenHui LIU JiYuan | 2017 | Science China Earth Sciences2017，60，12： | 13 |
| 3 | Daily variation characteristics of CO2 emission fluxes and contributions of environmental factors in semiarid grassland of Inner Mongolia, China显示文摘Fixed field experimental studies are carried out on daily variations of the undis- turbed community and soil respiration fluxes in different phenological phases of 2001―2002 in semiarid Aneurolepidium chinense steppe of Inner Mongolia, China using static black chamber method. Corresponding statistical analysis of the contributions of the water-heat factors (air temperature, ground temperature, surface soil water content) and ecological factors (above- ground biomass, underground biomass, litter biomass) to daily variation law of the undisturbed community and soil respiration fluxes as well as differences in daily respiration are also con- ducted. The results indicate that undisturbed community and soil respiration have apparent daily variation laws, daily variation patterns of respiration fluxes during different phenological phases are basically the same, and the variations of environmental factors only exert effect on CO2 emission intensities, while the effect on daily variation pattern of grassland CO2 emission fluxes is relatively small. The daily total respiration of the undisturbed community in different phenological phases ranges from 1.34―10.13 g·m?2; soil daily total respiration ranges from 0.98―5.17 g·m?2; both daily variations of undisturbed community and soil respiration fluxes are significantly corre- lated (p < 0.05) or extremely significantly correlated (p < 0.01) with air temperatures and ground surface temperatures, but the correlativity with the soil temperature at 5 and 10 cm depths is relatively weak; multiple regression analysis indicates that about 80% of the difference in daily respiration of the undisturbed community among different phenological phases is induced by the variation of the aboveground biomass, while the variations of the remaining factors can jointly explain around 20% of the daily respiration variations of the whole grassland ecosystem; about 83% of the soil daily respiration variation of the different phenological phases is caused by 0―20 cm underground biomass. Besides, surface soil water content is also an important environmental factor affecting soil daily respiration variations of the Aneurolepidium chinense steppe, but its partial correlation coefficient with soil daily respiration amount does not reach the significance level of 0.05. | QI Yuchun DONG Yunshe LIU Jiyuan GENG Yuanbo LI Mingfeng YANG Xiaohong LIU Lixin | 2005 | Science China Earth Sciences2005，48，7： | 11 |
| 4 | Impacts of ecological restoration projects on agricultural productivity in China显示文摘在农田数量和质量的变化由于陆地使用是国家食物安全的批评担心,特别地为中国。尽管有重要生态的效果,生态的恢复节目(ERP ) ,从 1999 开始了,显然改变了瓷器农田和农业生产率的空间模式。从 2000 ~ 2008 把动态数据基于农田首先与主要生产率建模的 30-m 分辨率和基于卫星的网源于卫星图象,我们在 ERP 引起的农业生产率上识别了影响,包括为格林的谷物,节目(GFGP ) 和到湖(RCTL ) 的回收农田编程序。我们的结果显示农业生产率与 132.67lis 的率输了。在 R 的射击的 Pb 的累积。pseudoacacia 比另外的种类显著地高。在学习区域的土壤的 Pb 的数量是 s 吗?? | QIN Yuanwei YAN Huimin LIU Jiyuan DONG Jinwei CHEN Jingqing XIAO Xiangming | 2013 | Journal of Geographical Sciences2013，23，3： | 8 |
| 5 | Physiological and ultralstructural changes of Chlorella sp. induced by UV-B radiation显示文摘In order to investigate the mechanisms of enhanced UV-B radiation on algae, the effects of UV-B radiation on the physiological and ultrastructural changes of Chlorella sp. were examined. The results showed that UV-B radiation could inhibit the growth and photosynthesis of microalgae. UV-B radiation at lower doses increased the photosynthetic pigment (chlorophyll a (Chla) and carotenoid (Car)) contents, while at higher doses of UV-B radiation Chla and Car contents were decreased. The ultrastructure of Chlorella sp. without exposure to UV-B showed that the thylakoid lamellae were clear and regular, the stroma of its chloroplast was apparent and clear. The globules with photosynthetic pigments and the cristae of mitochondria were clearly seen. After exposure to UV-B radiation at dose of 2.88 kJ/m2, the thylakoid lamellae of Chlorella sp. were lost and dissolved, the globules which contained photosynthetic pigments in chloroplast were bleached; some mitochondria cristae were dissolved; slight plasmolysis was found in some Chlorella sp. cells. After exposure to 5.76 kJ/m2 UV-B radiation, the thylakoid was in disarray and disintegration, plasmolysis was found in most cells, and the cell wall was broken and began to fall out. Many blank areas were observed in cells, mitochondria were seriously deformed and most of the mitochondria cristae were dissolved. Also, globules containing photosynthetic pigments in chloroplast were bleached and some empty globules were found in chloroplast. Therefore, UV-B radiation could damage cell structure of Chlorella sp., and this damage increased with the dose of UV-B radiation they exposed to. | YU Juan TANG Xuexi ZHANG Peiyu TIAN Jiyuan DONG Shuanglin | 2005 | Progress in Natural Science:Materials International2005，15，8： | 2 |
| 6 | Numerical study of primary steam superheating effects on steam ejector flow and its pumping performance显示文摘 | Xiaodong Wang Jingliang Dong Ao Li Hongjian Lei Jiyuan Tu | 2014 | Energy2014，，： | 1 |
| 7 | Numerical Re- search about the Internal Flow of Steam-Jet Vacuum Pump: Evaluation of Turbulence Models and Determiuation of the Shock-Mixing Layer 显示文摘 | Dong Jingliang Wang Xiaodong Tu Jiyuan | 2012 | Physics Procedia2012，32，： | 1 |
| 8 | Simulation of the long-term transfer and fate of DDT in Lanzhou, China显示文摘 | DONG Jiyuan WANG Shigong SHANG Kezheng | 2010 | Chemosphere2010，81，4： | 1 |
| 9 | Simulation of the transfer and fate of HCHs since the 1950s in Lanzhou, China显示文摘 | DONG Jiyuan GAO Hong WANG Shigong | 2009 | Ecotoxicology & Environmental Safety2009，72，7： | 1 |
| 10 | China's sloping land conversion program at the beginning of 21st century and its habitat suitability in typical region of Loess Plateau显示文摘 | Dong Jinwei Liu Jiyuan Shi Wenjiao | | 0，，01： | 1 |
| 11 | Simulation of thelong-term transfer and fate of DDT in Lanzhou,China显示文摘 | DONG Jiyuan WANG Shigong SHANG Kezheng | 2010 | Chemosphere2010，81，4： | 1 |
| 12 | The effects of enriched C0_(2) and enhanced UV-B radiation on ultrastructure of Dunaliella salina, singly and in combination显示文摘The effects of ambient CO2/ambient UV- B, enriched CO2/ambient UV- B, ambient CO2/enhanced UV- B, and enriched CO2/ enhanced UV- B on the ultrastructure of Dunaliella salina were investigated. (1) The ultrastructure of D. salina cell in the control experiment showed that the arrangement of thylakoid lamellae was regular, and there were many large starch grains among the thylakoid lamellae. A prominent well-developed pyrenoid was found in the middle of the chloroplast. Nucleus envelope and nucleolus were clearly ob- served. The Golgi apparatus accompanied by numerous vesicles with a compact arrangement of cisternae and the peripheral tips of the cisternae were swollen to a size comparable to that of some of the associated vesicles. (2) The ultrastructure of D. salina cell in en- riched CO2 showed that the arrangement of thylakoid was regular and the lamellae were vivid. Developed pyrenoids were found in the low-CO2-grown cells, but not in the high-CO2-grown cells. The mitochondria cristae were vivid. The arrangement of Golgi apparatus was compact. (3) The ultrastructure of D. salina cell in enhanced UV- B showed that the thylakoid was dissolved and the cells had a less developed pyrenoid or no detectable pyrenoid. Part of the nucleus envelope was dissolved. The number of mitochondria was in- creased and some mitochondria cristae were disintegrated. The starch grains were broken apart into many small starch grains. The Gol- gi apparatus with a loose arrangement of cisternae and the peripheral tips of the Golgi cisternae were not especially swollen, with sev- eral large associated vesicles. (4) The ultrastructure of D. salina cell in the enriched CO2/enhanced UV- B showed that part of the thy- lakoid and nucleus envelopes of some cells were dissolved. The pyrenoid was larger than that of the enhanced UV- B. There were many mitochondria between stroma and chloroplast membrane, but mitochondria cristae were partly dissolved. Many small starch grains were accumulated in cells. The starch sheath was broken into several discontinuous starch grains with different sizes. The ar- rangement of Golgi apparatus was loose. Above all, although the enriched CO2 can alleviate the damage induced by the UV- B radia- tion, the effects of experimental UV- B radiation were larger than the effects of actual UV- B radiation, the damage induced by the UV- B radiation was so severe, therefore, CO2 enrichment could not restore the ultrastructure to the control level. | YU Juan XIAO Hui TIAN Jiyuan ZHANG Peiyu DONG Shuanglin TANG Xuexi | 2006 | Acta Oceanologica Sinica2006，25，1： | 1 |
| 13 | The Performance Prediction and Enhancement of Steam Ejector on Respect of Different Geometry by CFD显示文摘 | Dong Jingliang Wang Xiaodong Tu Jiyuan | | 0，，： | 1 |
| 14 | Structure-based drug discovery of novel fusedpyrazolone carboxamide derivatives as potent and selective AXL inhibitors显示文摘a novel and promising antitumor target,AXL plays an important role in tumor growth,metastasis,immunosuppression and drug resistance of various malignancies,which has attracted extensive research interest in recent years.In this study,by employing the structure-based drug design and bioisosterism strategies,we designed and synthesized in total 54 novel AXL inhibitors featuring a fusedpyrazolone carboxamide scaffold,of which up to 20 compounds exhibited excellent AXL kinase and BaF3/TEL-AXL cell viability inhibitions.Notably,compound 59 showed a desirable AXL kinase inhibitory activity(IC_(50):3.5 nmol/L)as well as good kinase selectivity,and it effectively blocked the cellular AXL signaling.In turn,compound 59 could potently inhibit BaF3/TEL-AXL cell viability(IC_(50):1.5 nmol/L)and significantly suppress GAS6/AXL-mediated cancer cell invasion,migration and wound healing at the nanomolar level.More importantly,compound 59 oral administration showed good pharmacokinetic profile and in vivo antitumor efficiency,in which we observed significant AXL phosphorylation suppression,and its antitumor efficacy at 20 mg/kg(qd)was comparable to that of BGB324 at 50 mg/kg(bid),the most advanced AXL inhibitor.Taken together,this work provided a valuable lead compound as a potential AXL inhibitor for the further antitumor drug development. | Feifei Fang Yang Dai Hao Wang Yinchun Ji Xuewu Liang Xia Peng Jiyuan Li Yangrong Zhao Chunpu Li Danyi Wangh Yazhou Li Dong Zhang Dan Zhang Meiyu Geng Hong Liu Jing Ai Yu Zhou | 2023 | Acta Pharmaceutica Sinica B2023，13，12： | 0 |
| 15 | Chromosome-scale genome assembly of Prunus pusilliflora provides novel insights into genome evolution, disease resistance, and dormancy release in Cerasus L.显示文摘Prunus pusilliflora is a wild cherry germplasm resource distributed mainly in Southwest China.Despite its ornamental and economic value,a high-quality assembled P.pusilliflora genome is unavailable,hindering our understanding of its genetic background,population diversity,and evolutionary processes.Here,we de novo assembled a chromosome-scale P.pusilliflora genome using Oxford Nanopore,Illumina,and chromosome conformation capture sequencing.The assembled genome size was 309.62 Mb,with 76 scaffolds anchored to eight pseudochromosomes.We predicted 33035 protein-coding genes,functionally annotated 98.27%of them,and identified repetitive sequences covering 49.08%of the genome.We found that P.pusilliflora is closely related to Prunus serrulata and Prunus yedoensis,having diverged from them∼41.8 million years ago.A comparative genomic analysis revealed that P.pusilliflora has 643 expanded and 1128 contracted gene families.Furthermore,we found that P.pusilliflora is more resistant to Colletotrichum viniferum,Phytophthora capsici,and Pseudomonas syringae pv.tomato(Pst)DC3000 infections than cultivated Prunus avium.P.pusilliflora also has considerably more nucleotide-binding site-type resistance gene analogs than P.avium,which explains its stronger disease resistance.The cytochrome P450 and WRKY families of 263 and 61 proteins were divided into 42 and 8 subfamilies respectively in P.pusilliflora.Furthermore,81 MADS-box genes were identified in P.pusilliflora,accompanying expansions of the SVP and AGL15 subfamilies and loss of the TM3 subfamily.Our assembly of a high-quality P.pusilliflora genome will be valuable for further research on cherries and molecular breeding. | Songtao Jiu Baozheng Chen Xiao Dong Zhengxin Lv Yuxuan Wang Chunjin Yin Yan Xu Sen Zhang Jijun Zhu Jiyuan Wang Xunju Liu Wanxia Sun Guoqian Yang Meng Li Shufeng Li Zhuo Zhang Ruie Liu Lei Wang Muhammad Aamir Manzoor Quero-García José Shiping Wang Yahui Lei Ling Yang Elisabeth Dirlewanger Yang Dong Caixi Zhang | 2023 | Horticulture Research2023，10，5： | 0 |
| 16 | A convenient method for distinguishing human and mouse cells in situ显示文摘Animal models play critical roles in the field of biomedical research.Mouse models with transplanted human cells or tissues,such as cell line-derived xenografts(CDX)and patient-derived xenografts(PDX),have been widely used[1].Tracking transplanted cells and understanding the spatial relationship between donor and host are extremely important for the study of these models.To distinguish cell sources in mouse xenograft models at the morphological level,antibody recognition methods(immunohistochemistry and immunofluorescence),transgenic reporter methods,and chromosome-specific probe labeling methods are widely used[2–5].However,these methods all need to consider the issues of label specificity,signal intensity,in situ applicability,and complexity of experimental operations,which increase the difficulty in use.In this report,we described a simple method for accurately distinguishing human and mouse nuclei based on 4´,6-diamidino-2-phenylindole(DAPI)staining.This method can accurately identify species not only in cultured cells,but also in mouse xenograft models.Using short-wavelength excitation and high brightness of DAPI stains,this easy-to-use method is expected to be widely used in the field of biomedical research. | Yongqiang Wang Zixian Huang Kaishun Hu Jiangyun Peng Weicheng Yao Weixi Deng Jiyuan Zuo Yin Zhang Dong Yin | 2021 | Acta Biochimica et Biophysica Sinica2021，53，1： | 0 |
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